CN101791006A - Raw milk with high melatonin content and method for obtaining raw milk with high melatonin content - Google Patents
Raw milk with high melatonin content and method for obtaining raw milk with high melatonin content Download PDFInfo
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- CN101791006A CN101791006A CN201010152578A CN201010152578A CN101791006A CN 101791006 A CN101791006 A CN 101791006A CN 201010152578 A CN201010152578 A CN 201010152578A CN 201010152578 A CN201010152578 A CN 201010152578A CN 101791006 A CN101791006 A CN 101791006A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
Abstract
The invention discloses raw milk with high melatonin content and a method for obtaining the raw milk with high melatonin content, and relates to raw milk containing melatonin and a method for increasing the content of the melatonin in the raw milk. The invention solves the problem of the existing method for increasing the content of the melatonin in the raw milk that the content of lactose in the raw milk is low. The nutrition constituents in the raw milk include the melatonin, fat, protein, lactose, mineral substances and water. The method is characterized in that the feed of dairy cows during lactation period are divided into a light period, a dark period and a milking period according to illumination intensity, and then the raw milk with high melatonin content is obtained. The contents of the melatonin and the lactose in the raw milk are higher.
Description
Technical field
The present invention relates to a kind of method that contains the raw milk of epiphysin and improve melatonin content in the raw milk.
Background technology
Epiphysin can help to regulate the rhythm and pace of moving things of health, high epiphysin milk can help children to form the underdeveloped daily life rhythm and pace of moving things of birth fashion at night, there is research to point out to drink the milk that is rich in epiphysin, can improve old man's sleep quality, and increase their day's activities, also can from drink milk, be benefited for the young man.Good action based on epiphysin, epiphysin can be used as a dairy products market newcomer, but synthetic epiphysin can not exist as additive, natural biological epiphysin dairy products become the research focus, because the natural biological epiphysin is present in the raw milk more, therefore how to improve the content of epiphysin in the raw milk, become the most important thing of this research field.The MaijaValtonen professor of biochemistry research institute of Kuopio university; be universally acknowledged epiphysin expert; he has formulated a unique detection method; make its easier milk of monitoring melatonin levels exactly; and formulated secretion how to control the milk cow epiphysin; to realize best concentration epiphysin; for this innovation; this university patent protection (patent name is for producing the method for high epiphysin raw milk; application number is WO/2001/001784); and in this patent application, clearly put down in writing the method that how to improve melatonin content in the milk; though melatonin content is higher in the resulting raw milk of this method, lactose content is lower in the resulting raw milk of this method.
Summary of the invention
The objective of the invention is existing to improve the low problem of lactose content in the raw milk that the melatonin content method exists in the raw milk, and the high raw milk of a kind of melatonin content is provided and has obtained the method for the high raw milk of melatonin content in order to solve.
Nutritional labeling in the high raw milk of melatonin content of the present invention comprises epiphysin, fat, protein, lactose, mineral matter and water, and wherein the content of each nutritional labeling is in the raw milk: epiphysin 50 ~ 71pg/mL, fat 32 ~ 36mg/mL, protein 30 ~ 39mg/mL, lactose 44 ~ 56mg/mL, mineral matter 8 ~ 12mg/mL, water 880 ~ 920mg/mL.
The method that the present invention obtains the high raw milk of melatonin content is as follows: lactational raising dairy cattle is divided into illumination period, dark period according to intensity of illumination and adopts the milk phase, and illumination period is 540 ~ 600lux from 3 o'clock to 15 o'clock every day, intensity of illumination; Dark period from 15 o'clock to 2: 30 next day, dark period was that blue green light illumination 15 ~ 30min, the blue green light intensity of illumination of 420 ~ 480nm is 240 ~ 300lux every 1 ~ 2 hour with the illumination wavelength, and intensity of illumination is controlled to be 20 ~ 40lux remaining time outside the illumination of dark period blue green light; Adopting the milk phase is 2: 30~3: 00, and adopting the milk phase is that 420 ~ 480nm, intensity of illumination are that the blue green light of 240 ~ 300lux throws light on the illumination wavelength, has promptly obtained the high raw milk of melatonin content; The day feed of wherein every cow head feeding is 10 ~ 14kg, and the water that every cow head is drunk is 23 ~ 30kg, and feed is made up of the basal feed of 0.9 ~ 1.5kg, the red bean of 100 ~ 500g, the dusty yeast of 10 ~ 50mg and the millet of 100 ~ 200g.
The lactational raising dairy cattle of method of the present invention is divided into illumination period according to intensity of illumination, dark period and adopting the milk phase, pineal secretion plays positive facilitation to epiphysin in dark period, simultaneously, blue green light adopts batch (-type) illumination, but the sensitization gangliocyte on the repetitious stimulation retina, then light stimulus is conducted and given hypothalamus, conduct the pineal body of giving again, further accelerated the speed of secretion epiphysin, and the present invention adopt the milk phase adopt blue green light guarantee to adopt milk everything goes well with your work carry out in, do not influence pineal body secretion epiphysin, the raw milk that method of the present invention obtains detects as can be known through high performance liquid chromatography, the content of epiphysin is 50 ~ 71pg/mL in the raw milk, and method of the present invention has obtained the high raw milk of melatonin content; Feeding contains the feed of red bean, yeast and millet in the method for the present invention, red bean and millet enter in the cud and by the Institute of Micro-biology in the cud and decompose, and saccharomycete has improved the activity of carboxymethylcelluloenzyme enzyme, salicin enzyme and zytase in the cud, further improved the digest and decompose ability of cud, accelerate the decomposition of red bean and millet, promoted the generation of propionic acid, thereby accelerated the synthetic of lactose, the content of the lactose in the raw milk of the present invention is 44 ~ 56mg/mL, the lactose content height.
The specific embodiment
Technical solution of the present invention is not limited to the following cited specific embodiment, also comprises any combination between each specific embodiment.
The specific embodiment one: the nutritional labeling in the high raw milk of present embodiment melatonin content comprises epiphysin, fat, protein, lactose, mineral matter and water, and wherein the content of each nutritional labeling is in the raw milk: epiphysin 50 ~ 71pg/mL, fat 32 ~ 36mg/mL, protein 30 ~ 39mg/mL, lactose 44 ~ 56mg/mL, mineral matter 8 ~ 12mg/mL, water 880 ~ 920mg/mL.
The specific embodiment two: what present embodiment and the specific embodiment one were different is: the content of each nutritional labeling is in the raw milk: epiphysin 60 ~ 68pg/mL, fat 33 ~ 35mg/mL, protein 32 ~ 37mg/mL, lactose 48 ~ 52mg/mL, mineral matter 9 ~ 11mg/mL, water 890 ~ 910mg/mL.Other are identical with the specific embodiment one.
The specific embodiment three: what present embodiment and the specific embodiment one were different is: the content of each nutritional labeling is in the raw milk: epiphysin 60pg/mL, fatty 35mg/mL, protein 32mg/mL, lactose 52mg/mL, mineral matter 9mg/mL, water 910mg/mL.Other are identical with the specific embodiment one.
The specific embodiment four: what present embodiment and the specific embodiment one were different is: the content of each nutritional labeling is in the raw milk: epiphysin 68pg/mL, fatty 33mg/mL, protein 37mg/mL, lactose 48mg/mL, mineral matter 11mg/mL, water 890mg/mL.Other are identical with the specific embodiment one.
The specific embodiment five: what present embodiment and the specific embodiment one were different is: the content of each nutritional labeling is in the raw milk: epiphysin 65pg/mL, fatty 34mg/mL, protein 35mg/mL, lactose 50mg/mL, mineral matter 10mg/mL, water 900mg/mL.Other are identical with the specific embodiment one.
The specific embodiment six: what present embodiment was different with one of specific embodiment one to five is: also include cholesterol in the high raw milk of melatonin content, content of cholesterol is 0.13 ~ 0.5mg/mL in the raw milk.Other are identical with one of specific embodiment one to five.
The specific embodiment seven: what present embodiment was different with one of specific embodiment one to five is: also include cholesterol in the high raw milk of melatonin content, content of cholesterol is 0.2 ~ 0.4mg/mL in the raw milk.Other are identical with one of specific embodiment one to five.
The specific embodiment eight: what present embodiment was different with one of specific embodiment one to five is: also include cholesterol in the high raw milk of melatonin content, content of cholesterol is 0.3mg/mL in the raw milk.Other are identical with one of specific embodiment one to five.
The specific embodiment nine: what present embodiment was different with one of specific embodiment one to five is: also include cholesterol in the high raw milk of melatonin content, content of cholesterol is 0.4mg/mL in the raw milk.Other are identical with one of specific embodiment one to five.
The specific embodiment ten: what present embodiment was different with one of specific embodiment one to five is: also include cholesterol in the high raw milk of melatonin content, content of cholesterol is 0.2mg/mL in the raw milk.Other are identical with one of specific embodiment one to five.
The specific embodiment 11: present embodiment obtains the method for the high raw milk of melatonin content and carries out in accordance with the following methods: lactational raising dairy cattle is divided into illumination period, dark period according to intensity of illumination and adopts the milk phase, and illumination period is 540 ~ 600lux from 3 o'clock to 15 o'clock every day, intensity of illumination; Dark period from 15 o'clock to 2: 30 next day, dark period was that blue green light illumination 15 ~ 30min, the blue green light intensity of illumination of 420 ~ 480nm is 240 ~ 300lux every 1 ~ 2 hour with the illumination wavelength, and intensity of illumination is controlled to be 20 ~ 40lux remaining time outside the illumination of dark period blue green light; Adopting the milk phase is 2: 30~3: 00, and adopting the milk phase is that 420 ~ 480nm, intensity of illumination are that the blue green light of 240 ~ 300lux throws light on the illumination wavelength, has promptly obtained the high raw milk of melatonin content; The day feed of wherein every cow head feeding is 10 ~ 14kg, and the water that every cow head is drunk is 23 ~ 30kg, and feed is made up of the basal feed of 0.9 ~ 1.5kg, the red bean of 100 ~ 500g, the dusty yeast of 10 ~ 50mg and the millet of 100 ~ 200g.
Adopt the milk phase adopt blue green light guarantee to adopt milk everything goes well with your work carry out in, do not influence pineal body secretion epiphysin.
Illumination in the present embodiment is natural daylight.
Blue green light in the present embodiment is sent by light emitting diode, can buy from the market to obtain.
The raw milk that present embodiment obtains detects as can be known through high performance liquid chromatography, and the content of epiphysin is 50 ~ 71pg/mL in the raw milk, and the content of the lactose in the raw milk is 44 ~ 56mg/mL.
The specific embodiment 12: what present embodiment and the specific embodiment 11 were different is: the illumination period intensity of illumination is 560 ~ 580lux.Other steps and parameter are identical with the specific embodiment 11.
The specific embodiment 13: what present embodiment and the specific embodiment 11 were different is: the illumination period intensity of illumination is 560lux.Other steps and parameter are identical with the specific embodiment 11.
The specific embodiment 14: what present embodiment and the specific embodiment 11 were different is: the illumination period intensity of illumination is 580lux.Other steps and parameter are identical with the specific embodiment 11.
The specific embodiment 15: what present embodiment was different with one of specific embodiment 11 to 14 is: dark period was that blue green light illumination 20min, the blue green light intensity of illumination of 460nm is 260lux every 1.5 hours with the illumination wavelength.Other steps and parameter are identical with one of specific embodiment 11 to 14.
The specific embodiment 16: what present embodiment was different with one of specific embodiment 11 to 14 is: dark period was that blue green light illumination 30min, the blue green light intensity of illumination of 480nm is 260lux every 1 hour with the illumination wavelength.Other steps and parameter are identical with one of specific embodiment 11 to 14.
The specific embodiment 17: what present embodiment was different with one of specific embodiment 11 to 16 is: intensity of illumination is controlled to be 25 ~ 35lux remaining time outside the illumination of dark period blue green light.Other steps and parameter are identical with one of specific embodiment 11 to 16.
The specific embodiment 18: what present embodiment was different with one of specific embodiment 11 to 16 is: intensity of illumination is controlled to be 35lux remaining time outside the illumination of dark period blue green light.Other steps and ginseng
Number is identical with one of specific embodiment 11 to 16.
The specific embodiment 19: what present embodiment was different with one of specific embodiment 11 to 16 is: intensity of illumination is controlled to be 25lux remaining time outside the illumination of dark period blue green light.Other steps and parameter are identical with one of specific embodiment 11 to 17.
The specific embodiment 20: what present embodiment was different with one of specific embodiment 11 to 16 is: intensity of illumination is controlled to be 30lux remaining time outside the illumination of dark period blue green light.Other steps and parameter are identical with one of specific embodiment 11 to 16.
The specific embodiment 21: what present embodiment was different with one of specific embodiment 11 to 20 is: the day feed of every cow head feeding is 11 ~ 13kg.Other steps and parameter are identical with one of specific embodiment 11 to 20.
The specific embodiment 22: what present embodiment was different with one of specific embodiment 11 to 20 is: the day feed of every cow head feeding is 13kg.Other steps and parameter are identical with one of specific embodiment 11 to 20.
The specific embodiment 23: what present embodiment was different with one of specific embodiment 11 to 20 is: the day feed of every cow head feeding is 11kg.Other steps and parameter are identical with one of specific embodiment 11 to 20.
The specific embodiment 24: what present embodiment was different with one of specific embodiment 11 to 23 is: the water that every cow head is drunk is 25 ~ 28kg.Other steps and parameter are identical with one of specific embodiment 11 to 23.
The specific embodiment 25: what present embodiment was different with one of specific embodiment 11 to 23 is: the water that every cow head is drunk is 26kg.Other steps and parameter are identical with one of specific embodiment 11 to 24.
The specific embodiment 26: what present embodiment was different with one of specific embodiment 11 to 23 is: the day feed of every cow head feeding is 25kg.Other steps and parameter are identical with one of specific embodiment 11 to 24.
The specific embodiment 27: what present embodiment was different with one of specific embodiment 11 to 26 is: the day feed of every cow head feeding is 28kg.Other steps and parameter are identical with one of specific embodiment 11 to 26.
The specific embodiment 28: what present embodiment was different with one of specific embodiment 11 to 26 is: feed is made up of the basal feed of 1.1 ~ 1.3kg, the red bean of 200 ~ 400g, the dusty yeast of 20 ~ 40mg and the millet of 120 ~ 180g.Other steps and parameter are identical with one of specific embodiment 11 to 26.
The specific embodiment 29: what present embodiment was different with one of specific embodiment 11 to 26 is: feed is made up of the basal feed of 1.2g, the red bean of 300g, the dusty yeast of 30mg and the millet of 160g.Other steps and parameter are identical with one of specific embodiment 11 to 26.
The specific embodiment 30: what present embodiment was different with one of specific embodiment 11 to 26 is: feed is made up of the basal feed of 1.1kg, the red bean of 400g, the dusty yeast of 20mg and the millet of 180g.Other steps and parameter are identical with one of specific embodiment 11 to 26.
The specific embodiment 31: what present embodiment was different with one of specific embodiment 11 to 26 is: feed is made up of the basal feed of 1.3kg, the red bean of 200g, the dusty yeast of 40mg and the millet of 120g.Other steps and parameter are identical with one of specific embodiment 11 to 26.
The specific embodiment 32: what present embodiment was different with one of specific embodiment 11 to 31 is: basal feed is made up of 42 ~ 48 parts corn, 13 ~ 15 parts wheat bran, 31 ~ 33 parts cottonseed cake, 3 ~ 4 parts bone meal, 2 ~ 4 parts salt and 0.7 ~ 0.8 part sodium acid carbonate according to ratio of weight and number.Other steps and parameter are identical with one of specific embodiment 11 to 31.
The specific embodiment 33: what present embodiment was different with one of specific embodiment 11 to 31 is: basal feed is made up of 46 parts corn, 14 parts wheat bran, 32 parts cottonseed cake, 3.5 parts bone meal, 3 parts salt and 0.75 part sodium acid carbonate according to ratio of weight and number.Other steps and parameter are identical with one of specific embodiment 11 to 31.
The specific embodiment 34: what present embodiment was different with one of specific embodiment 11 to 31 is: basal feed is made up of 42 parts corn, 15 parts wheat bran, 31 parts cottonseed cake, 4 parts bone meal, 2 parts salt and 0.8 part sodium acid carbonate according to ratio of weight and number.Other steps and parameter are identical with one of specific embodiment 11 to 31.
The specific embodiment 35: what present embodiment was different with one of specific embodiment 11 to 31 is: basal feed is made up of 48 parts corn, 13 parts wheat bran, 33 parts cottonseed cake, 3 parts bone meal, 4 parts salt and 0.7 part sodium acid carbonate according to ratio of weight and number.Other steps and parameter are identical with one of specific embodiment 11 to 31.
The specific embodiment 36: the method that present embodiment obtains the high raw milk of melatonin content is as follows: lactational raising dairy cattle is divided into illumination period, dark period according to intensity of illumination and adopts the milk phase, and illumination period is 560lux from 3 o'clock to 15 o'clock every day, intensity of illumination; Dark period from 15 o'clock to 2: 30 next day, dark period was that blue green light illumination 20min, the blue green light intensity of illumination of 460nm is 260lux every 1.5 hours with the illumination wavelength, intensity of illumination is controlled to be 30lux remaining time outside the illumination of dark period blue green light; Adopting the milk phase is 2: 30~3: 00, and adopting the milk phase is that 460nm, intensity of illumination are that the blue green light of 260lux throws light on the illumination wavelength, has promptly obtained the high raw milk of melatonin content; The day feed of wherein every cow head feeding is 12kg, and the water that every cow head is drunk is 25kg, and feed is made up of the basal feed of 1.2kg, the red bean of 300g, the dusty yeast of 40mg and the millet of 150g.
Adopt the milk phase adopt blue green light guarantee to adopt milk everything goes well with your work carry out in, do not influence pineal body secretion epiphysin.
Blue green light in the present embodiment is sent by light emitting diode, can buy from the market to obtain.
Basal feed in the present embodiment is made up of 45 parts corn, 14 parts wheat bran, 32 parts cottonseed cake, 3.5 parts bone meal, 3 parts salt and 0.75 part sodium acid carbonate according to ratio of weight and number.
Adopting the method for present embodiment and application number respectively is the raw milk that the method for the high epiphysin raw milk of production of WO/2001/00178 record obtains to contain epiphysin, wherein the kind of milk cow in lactation period is Chinese holstein cattle, Xinjiang brown ox and Dutch dairy, and the result is as shown in table 1.
Table 1
From the data of table 1 as can be seen, the method of producing high epiphysin raw milk is for Dutch dairy, and the content of epiphysin is higher, but the content of lactose is all lower in the raw milk, and this method is for Chinese holstein cattle and Xinjiang ox, and the content of the content of lactose and epiphysin is all lower in the raw milk; Adopt no matter the method for present embodiment is Chinese holstein cattle and Xinjiang ox, or Dutch dairy, the content of epiphysin and lactose all is higher than the method for producing high epiphysin raw milk in the raw milk, the method of present embodiment that hence one can see that is not only applicable to the milk cow of national kind, be suitable for too for Dutch dairy, and the content of the content of lactose and epiphysin is all higher in the resultant raw milk of the method for present embodiment.
The acquisition of success of the present invention the high raw milk of melatonin content, and lactose content height in the raw milk, the present invention provides good raw material for China makes the dairy products that contain epiphysin, has filled up the present domestic blank that also is not rich in melatonin milk products.
Claims (10)
1. raw milk that melatonin content is high, it is characterized in that the nutritional labeling in the high raw milk of melatonin content comprises epiphysin, fat, protein, lactose, mineral matter and water, wherein the content of each nutritional labeling is in the raw milk: epiphysin 50 ~ 71pg/mL, fat 32 ~ 36mg/mL, protein 30 ~ 39mg/mL, lactose 44 ~ 56mg/mL, mineral matter 8 ~ 12mg/mL, water 880 ~ 920mg/mL.
2. the high raw milk of a kind of melatonin content according to claim 1 is characterized in that the content of each nutritional labeling in the raw milk is: epiphysin 60 ~ 68pg/mL, fat 33 ~ 35mg/mL, protein 32 ~ 37mg/mL, lactose 48 ~ 52mg/mL, mineral matter 9 ~ 11mg/mL, water 890 ~ 910mg/mL.
3. the high raw milk of a kind of melatonin content according to claim 1 and 2 is characterized in that also including cholesterol in the high raw milk of melatonin content, and content of cholesterol is 0.13 ~ 0.5mg/mL in the raw milk.
4. obtain the method for the high raw milk of melatonin content, the method that it is characterized in that obtaining the high raw milk of melatonin content is as follows: lactational raising dairy cattle is divided into illumination period, dark period according to intensity of illumination and adopts the milk phase, and illumination period is 540 ~ 600lux from 3 o'clock to 15 o'clock every day, intensity of illumination; Dark period was put 30 fens from 15 o'clock to next day, dark period was that blue green light illumination 15 ~ 30min, the blue green light intensity of illumination of 420 ~ 480nm is 240 ~ 300lux every 1 ~ 2 hour with the illumination wavelength, and intensity of illumination is controlled to be 20 ~ 40lux remaining time outside the illumination of dark period blue green light; Adopting the milk phase is 2: 30~3: 00, and adopting the milk phase is that 420 ~ 480nm, intensity of illumination are that the blue green light of 240 ~ 300lux throws light on the illumination wavelength, has promptly obtained the high raw milk of melatonin content; The day feed of wherein every cow head feeding is 10 ~ 14kg, and the water that every cow head is drunk is 23 ~ 30kg, and feed is made up of the basal feed of 0.9 ~ 1.5kg, the red bean of 100 ~ 500g, the dusty yeast of 10 ~ 50mg and the millet of 100 ~ 200g.
5. the method for the raw milk that acquisition melatonin content according to claim 4 is high is characterized in that the illumination period intensity of illumination is 560 ~ 580lux.
6. according to the method for the high raw milk of claim 4 or 5 described acquisition melatonin contents, it is characterized in that dark period was that blue green light illumination 20min, the blue green light intensity of illumination of 460nm is 260lux every 1.5 hours with the illumination wavelength.
7. the method for the raw milk that acquisition melatonin content according to claim 6 is high is characterized in that outside the illumination of dark period blue green light that remaining time, intensity of illumination was controlled to be 25 ~ 35lux.
8. according to the method for claim 4, raw milk that 5 or 7 described acquisition melatonin contents are high, it is characterized in that feed is made up of the basal feed of 1.1 ~ 1.3kg, the red bean of 200 ~ 400g, the dusty yeast of 20 ~ 40mg and the millet of 120 ~ 180g.
9. according to the method for claim 4, raw milk that 5 or 7 described acquisition melatonin contents are high, it is characterized in that feed is made up of the basal feed of 1.2kg, the red bean of 300g, the dusty yeast of 30mg and the millet of 160g.
10. the method for the raw milk that acquisition melatonin content according to claim 8 is high is characterized in that basal feed is made up of 42 ~ 48 parts corn, 13 ~ 15 parts wheat bran, 31 ~ 33 parts cottonseed cake, 3 ~ 4 parts bone meal, 2 ~ 4 parts salt and 0.7 ~ 0.8 part sodium acid carbonate according to ratio of weight and number.
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Cited By (2)
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CN106720376A (en) * | 2017-03-30 | 2017-05-31 | 辽宁辉山生物科技研究有限公司 | A kind of night adopts milk formulas milk powder and preparation method thereof |
CN115777624A (en) * | 2023-02-08 | 2023-03-14 | 北京三元食品股份有限公司 | Method for improving melatonin content in milk and application thereof |
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Cited By (3)
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CN106720376A (en) * | 2017-03-30 | 2017-05-31 | 辽宁辉山生物科技研究有限公司 | A kind of night adopts milk formulas milk powder and preparation method thereof |
CN115777624A (en) * | 2023-02-08 | 2023-03-14 | 北京三元食品股份有限公司 | Method for improving melatonin content in milk and application thereof |
CN115777624B (en) * | 2023-02-08 | 2023-09-26 | 北京三元食品股份有限公司 | Method for increasing melatonin content in milk and application thereof |
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