CN101775347A - Health-care vinegar, vinegar drink preparation method and anti-alcohol liver-protection application thereof - Google Patents
Health-care vinegar, vinegar drink preparation method and anti-alcohol liver-protection application thereof Download PDFInfo
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Abstract
The invention provides health-care vinegar, a vinegar drink preparation method and anti-alcohol liver-protection application thereof. The method comprises the following steps: (1) grinding rice and kudzuvine root into thick liquid with water, regulating the concentration of starch to be over 10 percent with sterile water or traditional Chinese medicinal extract, and heating the mixture at the temperature of between 125 and 130 DEG C; (2) adding rhizopus, activated dried yeast, aroma-producing yeast and lactic acid bacteria into the sterilized mixture to ferment distilled wort, and stopping alcoholic fermentation when the alcohol content is between 10 and 15 percent; (3) regulating the alcohol concentration to be between 6 and 8 percent with the sterile water or the traditional Chinese medicinal extract, adding acetic acid bacteria solution which is 10 percent of fermentation broth by volume into the mixture at the temperature of between 26 and 34 percent, and stopping fermentation until the acidity of the fermentation broth is between 4 and 6 percent; and (4) ageing the fermented acid solution for over 15 days at the temperature of between 12 and 20 DEG C, and filtering the solution to obtain the health-care vinegar. The invention extracts effective ingredients of traditional Chinese medicament in a flash way to perform alcohol fermentation and acetic fermentation with the kudzuvine root and the rice, not only can effectively maintain the effective ingredients of the traditional Chinese medicament, but also can better play the functions of relieving alcohol, dispelling the effect of alcohol and protecting liver.
Description
Technical field
The present invention relates to a kind of preparation method with quick relieving alcoholism and protecting liver health vinegar and beverage thereof.
Background technology
Acute alcoholism is meant that once drink goes into central nervous system that excessive alcohol or inebriant cause is transferred to inhibition by excitement state.This disease is common clinical, frequently-occurring disease, grievous injury patient body health not only, and very easily cause a series of social concerns.Along with growth in the living standard, the number of the acute alcoholism that China causes by drinking beyond one's capacity is more and more, and the social concern that causes therefrom is also more and more.Therefore, how the treatment of acute alcoholism and the prevention harmonious development to entire society is had great significance.Control main quiet of Narlan that adopts on doctor trained in Western medicine to acute alcoholism cooperates symptomatic treatment at present; though can comparatively fast impel acute alcoholism person clear-headed; but alcohol metabolism there is not definite influence; and the various malaise symptoms in back of waking up still exist; therefore developing a kind of can urging fast wakes up; accelerate alcohol metabolism and protection liver, the taste food that relieves the effect of alcohol preferably has great social significance and economic worth.
Vinegar production has long history in China, and its health-care effect is confirmed in practice.The vinegar of fermentation contains rich nutrient contents, as acetic acid, newborn vinegar, grape acid, succsinic acid etc., the nutritive ingredient that needed by human body such as multiple amino acids, sugar, glycerine are wanted.Particularly effect such as can improve liver function, detoxify and enhance metabolism such as acetic acid, lactic acid, oxysuccinic acid, succsinic acid, amino acid.In addition, show according to the study that vinegar also has the effect of removing free radical.The topmost in vivo metabolic characteristic of alcohol is to be oxidized to acetaldehyde and water under the effect of the ethanol dehydrogenase of liver cytoplasm, changes into acetate again, further transforms into CO at last again
2And H
2O.If ethanol content is too high, cellular metabolism is disturbed, and can produce free radical, promotes liver injury.If can be in conjunction with vinegar specific, the Chinese medicine of selecting for use some to have antialcoholism function ferments, and develops a kind of relieving alcoholism and protecting liver health vinegar, has good meaning.
The root of kudzu vine is the Chinese medicine of integration of drinking and medicinal herbs, also is a kind of clinical medicine that relieves the effect of alcohol commonly used, and wherein puerarin, Daidzin and daidzein are its main effective constituent, can reduce ethanol in blood concentration, promotes alcohol metabolism, the protection liver.Trifoliate orange seed is the dry mature seed of Rhamnaceae plant trifoliate orange Dulcis, and trifoliate orange seed is the seed of Rhamnaceae plant honey raisin tree, is the food that relieves the effect of alcohol commonly used among the people.Have data to prove, it can reduce alcohol concn in the acute alcoholism body, shortens and sobers up the time, has deinebriating effect.Semen Myristicae has oxidation resistant effect, and the traditional Chinese medical science is thought the function of warm stomach, antidiarrheal, promoting the circulation of qi, is to use more Sobering-up Chinese medicine simply.In the patent of in the past traditional Chinese medicine anti-inebriation beverage beverage, all be to adopt to decoct to Chinese medicine, this mode is destroyed bigger to some effective constituents of Chinese medicine.
Summary of the invention
Based on above background, the object of the invention is to provide a kind of short waking up of can relieving the effect of alcohol fast to have the health vinegar of liver protection effect and the preparation method of vinegar beverage thereof again.
To achieve these goals, the present invention adopts following technical scheme:
A kind of brewing method of health vinegar comprises the steps:
(1) getting rice 4-6 part cleans the back, dries;
(2) the fresh root of kudzu vine is cleaned, removes the peel, gone get 4-6 part behind the spot, the rice with step (1) gained adds the water mill slurry then, adopts aqua sterilisa or Chinese medicine extract to adjust starch quality concentration more than 10%, and heating is 5-10 minute under 125-130 ℃ of condition;
(3) mixture after will sterilizing adds head mold, activation dry yeast, SHENGXIANG yeast and becomes distiller's wort with lactobacillus-fermented, stops zymamsis when detecting the alcohol volume content for 10-15%;
(4) adopting aqua sterilisa or Chinese medicine extract to adjust the alcohol volumetric concentration is 6-8%, adds the acetic bacteria liquid that accounts for fermented liquid 10% volume then, and leavening temperature is 26-34 ℃, is to stop fermentation at 4 ~ 6% o'clock up to fermented liquid acidity;
(5) ageing under 12-20 ℃ of condition of the vinegar liquid after will fermenting filtered more than 15 days, promptly got this health vinegar.
Resulting health vinegar is added the aqua sterilisa dilution, add sugar, can obtain vinegar beverage.Sugar is preferably sucrose, glucose, fructose or honey.
In above-mentioned brewing method, described Chinese medicine extract carries out water extraction by the component mixing of following weight part and obtains: hawthorn 2-4 part, trifoliate orange seed 3-6, Semen Myristicae 1-3 part and chrysanthemum 1-3 part.
In above-mentioned brewing method, described Chinese medicine extract is extracted by following steps and obtains: get hawthorn 2-4 weight part, trifoliate orange seed 3-6 weight part, Semen Myristicae 1-3 weight part and chrysanthemum 1-3 weight part, add 6～10 times of volume water, decoct and extract 2～3 times, each 0.5～3 hour, filter merging filtrate, be condensed into relative density 1.05～1.15, promptly.
Compared with prior art, the present invention has following beneficial effect:
The present invention is by the effective constituent in the sudden strain of a muscle formula extraction Chinese medicine, carry out zymamsis and acetic fermentation with the root of kudzu vine and glutinous rice, can keep the effective constituent in the Chinese medicine effectively, can bring into play the function of relieving the effect of alcohol, sobering up and protecting liver better again, and adopt the deep layer liquid-state fermentation technology, solved the slow problem of solid state fermentation acid production speed.
Animal experiment proves; this health vinegar and vinegar beverage can reduce alcohol concn in the serum of acute alcoholism mice, the concentration that reduces mda in the hepatic tissue and the content of rising reduced form glutathione, have proved that this health vinegar and vinegar beverage have to sober up fast to relieve the effect of alcohol and liver-protective effect.
Embodiment
Below the invention will be further described by specific embodiment and test example.
Embodiment 1:
(1) getting rice 100kg cleans the back, dries;
(2) the fresh root of kudzu vine is cleaned, removes the peel, goes to get 150kg behind the spot, the Mi Yiqi with step (1) gained adds the water mill slurry then, adjusts starch quality concentration more than 10%, and heating is 5-10 minute under 125-130 ℃ of condition;
(3) mixture after will sterilizing adds 0.2% head mold, 0.4% activation dry yeast, 0.1% SHENGXIANG yeast and 1% lactobacillus-fermented and becomes distiller's wort, detects the alcohol volume content and is at 10% o'clock and stop zymamsis;
(4) adjusting the alcohol volumetric concentration with sterilized water is 6%, and the acetic bacteria that adds content then and be fermented liquid 10% is in fermented liquid, and leavening temperature is 30 ℃, stops fermentation when fermented liquid acidity is 5% left and right sides;
(5) ageing under 12 ℃ of conditions of the vinegar liquid after will fermenting filtered more than 25 days, promptly got this health vinegar.
Embodiment 2:
(1) getting rice 150Kg cleans the back, dries;
(2) the fresh root of kudzu vine is cleaned, removes the peel, goes to get 100kg behind the spot, the Mi Yiqi with step (1) gained adds the water mill slurry then, adjusts starch quality concentration more than 10%, and heating is 5-10 minute under 125-130 ℃ of condition;
(3) mixture after will sterilizing adds 0.1% head mold, 0.3% activation dry yeast, 0.2% SHENGXIANG yeast and 2% lactobacillus-fermented and becomes distiller's wort, detects the alcohol volume content and is at 10% o'clock and stop zymamsis;
(4) adjusting the alcohol volumetric concentration with sterilized water is 6%, and the acetic bacteria that adds content then and be fermented liquid 10% is in fermented liquid, and leavening temperature is 30 ℃, stops fermentation when fermented liquid acidity is 5% left and right sides;
(5) ageing at last must this health vinegar with ceramic membrane ultrafitration more than 20 days under 15 ℃ of conditions for the vinegar liquid after will fermenting.
Embodiment 3:
Press embodiment 1 used brewing method and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (2) replaces water to adjust starch concentration, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 10kg, trifoliate orange seed 30kg, Semen Myristicae 5kg and chrysanthemum 15kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 4:
Press embodiment 1 used brewing method and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (2) replaces water to adjust starch concentration, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 400kg, trifoliate orange seed 15g, Semen Myristicae 15kg and chrysanthemum 5kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 5:
Press embodiment 1 used brewing method and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (4) replaces water to adjust ethanol concn, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 10kg, trifoliate orange seed 30kg, Semen Myristicae 5kg and chrysanthemum 15kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 6:
Press embodiment 1 used brewing method and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (4) replaces water to adjust ethanol concn, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 40kg, trifoliate orange seed 15kg, Semen Myristicae 15kg and chrysanthemum 5kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 7:
Press embodiment 2 used brewing methods and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (2) replaces water to adjust starch concentration, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 10kg, trifoliate orange seed 30kg, Semen Myristicae 5kg and chrysanthemum 15kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 8:
Press embodiment 2 used brewing methods and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (2) replaces water to adjust starch concentration, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 40kg, trifoliate orange seed 15kg, Semen Myristicae 15kg and chrysanthemum 5kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 9:
Press embodiment 2 used brewing methods and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (4) replaces water to adjust ethanol concn, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 10kg, trifoliate orange seed 30kg, Semen Myristicae 5kg and chrysanthemum 15kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 10:
Press embodiment 2 used brewing methods and produce blood sugar reducing health vinegar, only the extracting solution that decocts with integration of drinking and medicinal herbs in step (4) replaces water to adjust starch concentration, and the preparation method of this extracting solution is as follows:
(1) getting hawthorn 40kg, trifoliate orange seed 15kg, Semen Myristicae 15kg and chrysanthemum 5kg respectively mixes;
(2) add 10 times of decoctings and boil three times, each 1 hour, merge three times cooking liquor, filter, concentrate.
Embodiment 11:
Press the health vinegar of embodiment 1-10 gained, carry out the evaluation of effective constituent, adopt nutrition and functional component in the analysis evaluation health vinegar such as high performance liquid chromatography-mass spectrometry, gas chromatograph-mass spectrometer, gas-chromatography, infrared spectroscopy.Analyze this health vinegar after testing and contain terpene substances such as Flavonoid substances such as acetic acid, lactic acid, oxysuccinic acid, Citric Acid, succsinic acid, citric acid, puerarin, Quercetin and dibydro myricetrin, ursolic acid and amino acid etc.
Embodiment 12:
Relieving alcoholism and protecting liver vinegar is to the antialcoholism action of experimental acute alcoholism mice fast
Animal grouping: healthy Kunming mouse (SPF level), male and female half and half, body weight 18-20g (experimentation on animals center, Guangdong Province provides), be divided into dosage group and anti-alcohol vinegar low dose group in blank group, positive controls (Pepp regain consciousness chewable tablet 1.3g/kg), modeling group (pouring into isometric(al) physiological saline), Chinese medicine compound extracted solution (comprising the root of kudzu vine, hawthorn, trifoliate orange seed, Semen Myristicae, chrysanthemum) group, anti-alcohol vinegar high dose group, the anti-alcohol vinegar at random, 11 every group.All by gastric infusion, blank group, modeling group are irritated stomach equal-volume tap water, and administration 7 days was weighed and once to be adjusted dosage in per 2 days.
Concentration of ethanol in serum: administration in the 7th day finishes back 30min, press 14ml/kg and irritate stomach 50% ethanol, blank group is irritated stomach equal-volume distilled water, after prohibiting water fasting 16h, eye socket is got blood and is put to death mouse, cuts open immediately and gets liver, clean with the precooling normal saline flushing, filter paper blots, and weighs, and 1.15% physiological saline that added precooling by 1: 10 is made liver homogenate.With ethanol concn in the gas chromatography determination serum of low latitude, chromatographic condition: chromatographic column is HP-20M (Carbowax 20M, 25m * 0.32mm * 0.3 μ m); Interior mark: n-propyl alcohol.
Mda and reduced glutathione concentration: with liver homogenate liquid
, 3000 leave heart 10min, get supernatant liquor and measure mda and glutathione concentrations in the mouse liver homogenate according to the test kit specification sheets.
Use the excel processing data, spss software package analytical data carries out homogeneity test of variance earlier, adopts the LSD method to carry out the modeling group when variance is neat and compares in twos with other groups, adopts the Games-Howell method to carry out the modeling group when heterogeneity of variance and compares in twos with other groups.
Ethanol content in the serum after table 1 administration
Annotate:
*P＜0.05vs model group
*P＜0.01vs model group
ΔP＜0.05vs is on the same group before the administration
The Δ ΔP＜0.01vs is on the same group before the administration
The concentration of mda and glutathione concentrations in table 2 hepatic tissue
Annotate:
*P＜0.05vs model group
Claims (7)
1. the brewing method of a health vinegar is characterized in that comprising the steps:
(1) getting rice 4-6 part cleans the back, dries;
(2) the fresh root of kudzu vine is cleaned, removes the peel, gone get 4-6 part behind the spot, the rice with step (1) gained adds the water mill slurry then, adopts aqua sterilisa or Chinese medicine extract to adjust starch quality concentration more than 10%, and heating is 5-10 minute under 125-130 ℃ of condition;
(3) mixture after will sterilizing adds head mold, activation dry yeast, SHENGXIANG yeast and becomes distiller's wort with lactobacillus-fermented, stops zymamsis when detecting the alcohol volume content for 10-15%;
(4) adopting aqua sterilisa or Chinese medicine extract to adjust the alcohol volumetric concentration is 6-8%, adds acetic bacteria liquid then, and leavening temperature is 26-34 ℃, is to stop fermentation at 4 ~ 6% o'clock up to fermented liquid acidity;
(5) ageing under 12-20 ℃ of condition of the vinegar liquid after will fermenting filtered more than 15 days, promptly got this health vinegar.
2. brewing method according to claim 1 is characterized in that described Chinese medicine extract carries out water extraction by the component mixing of following weight part and obtains: hawthorn 2-4 part, trifoliate orange seed 3-6, Semen Myristicae 1-3 part and chrysanthemum 1-3 part.
3. brewing method according to claim 1, it is characterized in that described Chinese medicine extract is obtained by the following steps extraction: get hawthorn 2-4 weight part, trifoliate orange seed 3-6 weight part, Semen Myristicae 1-3 weight part and chrysanthemum 1-3 weight part, add 6～10 times of volume water, decoct and extract 2～3 times, each 0.5～3 hour, filter merging filtrate, be condensed into relative density 1.05～1.15, promptly.
4. health vinegar that obtains by the described brewing method of claim 1.
5. the preparation method of a vinegar beverage, it is characterized in that comprising the steps: that health vinegar with claim 1 gained adds the aqua sterilisa dilution after, add sugar, promptly.
6. preparation method as claimed in claim 5 is characterized in that described sugar is sucrose, glucose, fructose or honey.
7. the application of the described health vinegar of claim 4 in preparation relieving alcoholism and protecting liver medicine or protective foods.
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| CN102676366A (en) * | 2012-05-29 | 2012-09-19 | 南君涛 | Hovenaia dulcis vinegar |
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| CN102676366A (en) * | 2012-05-29 | 2012-09-19 | 南君涛 | Hovenaia dulcis vinegar |
| CN102911849A (en) * | 2012-11-16 | 2013-02-06 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing agaricus blazei murrill wine through agaricus blazei murrill liquid fermentation products added with pueraria lobota slag |
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| CN103897976A (en) * | 2014-04-30 | 2014-07-02 | 彭常钧 | Processing method of honey raisin tree fruit vinegar |
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| CN107513488A (en) * | 2017-10-24 | 2017-12-26 | 广州市旺民实业有限公司 | Tie up arrowroot beverage vinegar and preparation method thereof |
| CN108546625A (en) * | 2018-03-28 | 2018-09-18 | 何治伟 | A kind of preparation method of probiotics anti-alcohol vinegar |
| CN109880732A (en) * | 2019-04-11 | 2019-06-14 | 天津科技大学 | A kind of relieving alcoholism and protecting liver fruit vinegar beverage and preparation method thereof |
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