CN101766557A - Whitening cosmetic compound - Google Patents
Whitening cosmetic compound Download PDFInfo
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- CN101766557A CN101766557A CN200810233781A CN200810233781A CN101766557A CN 101766557 A CN101766557 A CN 101766557A CN 200810233781 A CN200810233781 A CN 200810233781A CN 200810233781 A CN200810233781 A CN 200810233781A CN 101766557 A CN101766557 A CN 101766557A
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Abstract
The invention discloses a whitening cosmetic compound, which consists of flores tiliae extract, mulberry root extract, tropaeolum majus extract and the other cosmetic substrate; Wherein, the ratios of the flores tiliae extract, the mulberry root extract, the tropaeolum majus extract in the total weight of the compound are respectively 1 percent to 20 percent. The preparation form of the compound can be selected as cosmetic water, liquid cream, cream, skin essence, massage ointment and gelled polymers. After three components are combined, the compound thereof has the efficacy of spot removing, spot dissolving, spot diluting and whitening as well as moisture retaining. The efficacy is significant and consolidated. And as the compound contains active components of natural plants, the stimulation to skin is small, the invention is a skin whitening agent compound which is safe and has a certain health function for skin, and the invention meets the safety requirement of people on cosmetics.
Description
One, technical field
The present invention relates to a kind of cosmetics that are specifically designed to human skin, particularly a kind of cosmetic composition of Pear Power effect.
Two, background technology
Have many reasons to cause people's skin darkening, wherein, the contact ultraviolet is well-known.In case the contact skin ultraviolet enlivens synthesis of melanin in the dermal melanin cell, and is discharged into epidermis.Melanin in the melanocyte is synthetic to be mediated by tryrosinase.Specifically, cell tyrosine is converted into the DOPA quinone by tryrosinase, produces melanin from it by spontaneous enzyme reaction.Therefore, melanic generation can be reacted by some of blocking-up melanin route of synthesis and be suppressed, and this notion has been suppressed the typical method of skin darkening and has accepted.
The conventional whitening agent that uses has kojic acid, hydroquinone, arbutin etc., by the copper ion in the sequestration tyrosinase activity site, plays the effect of inhibitory enzyme activity.Although but they have high tyrosinase inhibitory activity, also can not be widely used because of the safety problem of they and other cosmetic material intermiscibility difference and chafe.
Three, summary of the invention
Many in recent years discovering, there are a lot of medical herbs can make whiteness of skin, comprise: the extract of Radix Glycyrrhizae, Radix Paeoniae, Cortex Cinnamomi, Radix Sophorae Flavescentis, wild Radix Puerariae, Radix Sophorae Flavescentis etc. has the activity of restraint of tyrosinase, and the invention provides a kind of is the whitening cosmetic compound of main active with Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract etc.
Be specially:
A kind of whitening cosmetic compound is made up of Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract and other cosmetic bases.Wherein, to account for the composition total weight proportioning respectively be 1%-20% for Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract.Other cosmetic base is conventional emollient, wetting agent, emulsifying agent, dispersant, antioxidant, solvent, aromatic, the antiseptic that uses, and among vitamin C derivatives, arbutin, kojic acid, Radix Notoginseng extract, Cortex Mori extract, Radix Angelicae Sinensis extract, black rice extract, coenzyme Q10, Radix Glycyrrhizae extract, citron extract, vitamin C, vitamin E, vitamin B3 and the B5 one or more.
When preparation Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract activated feedstock, can from Flos tiliae miquelianae, Fructus Mori root, nasturtium, obtain respectively by drying, washing, solvent extraction, ageing and filtration, concentration step.The solvent for use extracting all is to use water and ethanol to carry out in leaching process, or makes water separately or unite 1,3 butanediol or propylene glycol carries out.Use distilling under reduced pressure when concentrating, temperature is 60-70 ℃, and pressure is 100-120Pa.
The dosage form of compositions can be selected cosmetic water, moisturizer, cream, essence, massage cream, gelatinous product, promptly can be used for the daily care program of family, also can be used for the care program of beauty parlor.
Concrete experiment is as follows:
(1) tryrosinase suppresses experiment:
Reaction generates in the melanic process, and the catalytic action of tryrosinase mainly is to occur in that tyrosine is converted into the L-DOPA and the L-DOPA is converted in these two reactions of DOPA quinone.The DOPA quinone is a coloring matter, can observe and measure with ultraviolet spectrometer (475nm).
(2) cell experiment:
Animal subject is added in the B16 mouselet melanoma cell of In vitro culture, cultivated 48 hours, observe the influence of animal subject cell growth, collect the cell on each culture dish more respectively, carry out light color degree (seeing the following form) centrifugal, that observe harvesting.
Whitening agent is to the influence of B16 cell growth
| Animal subject | Viable count (individual/ml) | The light color degree of harvesting |
| Blank | ??5.0×10 5 | ??0 |
| Lightening compositions (embodiment 1) | ??5.6×10 5 | ??++++ |
| Arbutin | ??0 | ??++ |
| L-lactic acid | ??0 | ??+++ |
++ ++ expression cell light color degree is the highest
+++expression cell light color degree is higher
++ expression cell light color degree is general
Result of the test shows that the said lightening compositions pair cell of the present invention light color degree is the highest, and the ability that suppresses the generation of B 16 cell melanin is the strongest, and L-lactic acid takes second place, and arbutin is minimum, and the present invention has no side effect to human body skin.
The present invention is based upon under the Chinese herbal medicine research background for many years, having chosen the Flos tiliae miquelianae extract, Fructus Mori root extract, the nasturtium extract that obtain through purification refine cooperates other cosmetic base feedstock production to form, work in coordination with after three components cooperate and have the effect of speckle dispelling, molten speckle, light speckle and whitening skin and preserving moisture, obvious, the consolidation of curative effect.And because be active components of natural plants, little to skin irritation, be a kind of safe, skin is had the skin-whitening agents compositions of certain function of health care, meet the requirement of people to cosmetics safety.
Four, the specific embodiment
Embodiment 1:
A kind of whitening cosmetic compound is made up of Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract and other cosmetic bases, and its dosage form is a cleawhite over-night essences.When preparation Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract activated feedstock, can from Flos tiliae miquelianae, Fructus Mori root, nasturtium, obtain respectively by drying, washing, solvent extraction, ageing and filtration, concentration step.The solvent for use extracting all is to use water and ethanol to carry out in leaching process, or makes water separately or unite 1,3 butanediol or propylene glycol carries out.Use distilling under reduced pressure when concentrating, temperature is 60-70 ℃, and pressure is 100-120Pa.
Concrete prescription (by weight percentage):
Flos tiliae miquelianae extract 10.0%
Fructus Mori root extract 8.5%
Nasturtium extract 7.5%
Hyaluronic acid 0.01%
Dispersion agent 2.0%
Aloe gel 5.0%
Antiseptic, essence are an amount of
Deionized water is added to 100.0%
Stir under the above each component room temperature, in the disinfectant bottle of packing into, get final product.
Embodiment 2:
A kind of whitening cosmetic compound is made up of Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract and other cosmetic bases, and its dosage form is the freckle removing and whitening revitalizer.Preparation Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract activated feedstock are with embodiment 1.
Concrete prescription (by weight percentage):
A: Flos tiliae miquelianae extract 1.0% B: tristerin 2.5%
Fructus Mori root extract 3.0% stearic acid 1.0%
Nasturtium extract 4.0% certain herbaceous plants with big flowers acid glycerol three esters 6.5%
The 0.5% ethyl acetic acid cetearyl alcohol acid 6.0% of glucose wetting agent
Card ripple glue 0.2% cocos nucifera oil certain herbaceous plants with big flowers ester 5.0%
Emulsifying agent 3.0% American Avocado Tree oil 3.0%
Antiseptic, essence are an amount of
Deionized water is added to 100%
The mix homogeneously after 75-80 ℃ of fusing with A phase component and appropriate amount of deionized water, this is a liquid A.With B phase component mix homogeneously after 75-80 ℃ of fusing, this is a liquid B.Liquid A and liquid B are mixed emulsifying stir, and be cooled to 40-45 ℃, add an amount of antiseptic, essence continues to stir, in the disinfectant bottle of packing into, get final product.
Embodiment 3:
A kind of whitening cosmetic compound is made up of Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract and other cosmetic bases, and its dosage form pastes for the cleawhite pack of preserving moisture.Preparation Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract activated feedstock are with embodiment 1.
Concrete prescription (by weight percentage):
Flos tiliae miquelianae extract 20.0%
Fructus Mori root extract 2.5%
Nasturtium extract 3.5%
Propylene glycol 3.0%
Hyaluronic acid 2.0%
Water-soluble gel 10.0%
Waterborne-type preservation, essence are an amount of
Deionized water adds to 100%
Water-soluble gel, propylene glycol, hyaluronic acid are added in the appropriate amount of deionized water, mix homogeneously, the degassing, Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract, Aloe extract are added wherein, stir, add waterborne-type preservation, essence, balance of deionized water water again and stir, facial mask liquid.The non-woven fabrics facial film is pasted folding, in the disinfectant aluminum foil bag of packing into, quantitatively add facial mask liquid, seal, ultraviolet disinfection gets final product.
Above-mentioned cleawhite over-night essences, freckle removing and whitening revitalizer, the cleawhite pack of preserving moisture are attached to the clinical potency test of having carried out, and use color difference meter its effect has been carried out the assessment observation.
The volunteer is 50 women about 35 years old, and position on probation is a face; After clean, be applied to the test position for twice on the one, observe with the test position be the narrow positions of two faces, the contrast position is untreated right forearm inboard.At the beginning of time on-test is midsummer: measured a position respective value with color difference meter before on-test on June 15th, 2008, measured once in after this every month.Show through overtesting:, have obviously before its L-value (lightness) uses and increase (P＜0.05%) through trimestral use.The right forearm inboard at position L-value (lightness) in entire test has decline in contrast.This result of the test shows that this lightening compositions can not only increase facial lightness, and can resist the blackening effect of ultraviolet to skin.
Claims (3)
1. whitening cosmetic compound, it is characterized in that: form by Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract and other cosmetic bases, wherein, to account for the composition total weight proportioning respectively be 1%-20% for Flos tiliae miquelianae extract, Fructus Mori root extract, nasturtium extract.
2. a kind of whitening cosmetic compound according to claim 1, it is characterized in that: the solvent for use extracting in leaching process of Caulis Hederae Sinensis extract, Radix Orthosiphonis Wulfenioidis extract is to use water and ethanol to carry out, or make water separately or unite 1,3 butanediol or propylene glycol carries out.
3. a kind of whitening cosmetic compound according to claim 1 is characterized in that: the dosage form of compositions can be selected cosmetic water, moisturizer, cream, essence, massage cream, gelatinous product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810233781A CN101766557A (en) | 2008-12-31 | 2008-12-31 | Whitening cosmetic compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810233781A CN101766557A (en) | 2008-12-31 | 2008-12-31 | Whitening cosmetic compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101766557A true CN101766557A (en) | 2010-07-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810233781A Pending CN101766557A (en) | 2008-12-31 | 2008-12-31 | Whitening cosmetic compound |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102257962A (en) * | 2011-06-09 | 2011-11-30 | 中国科学院植物研究所 | Method for obtaining banyan regeneration plants by tissue culture and culture medium thereof |
| CN102836098A (en) * | 2012-09-14 | 2012-12-26 | 刘婷 | Chinese medicinal herb composition beauty essence |
| CN102895173A (en) * | 2012-10-31 | 2013-01-30 | 倪金福 | Whitening cleansing cream |
| CN104288019B (en) * | 2014-09-25 | 2016-10-26 | 江苏奇力康皮肤药业有限公司 | A kind of moisturizing Aloe glue and preparation method thereof |
| CN108272736A (en) * | 2018-04-19 | 2018-07-13 | 王风云 | A kind of toner and preparation method thereof with high activity |
| CN109771346A (en) * | 2019-03-11 | 2019-05-21 | 广东大鹏医药科技有限公司 | A kind of lily feet flower composition and its preparation and use with whitening ecchymose removing function |
| CN111973538A (en) * | 2020-07-16 | 2020-11-24 | 重庆珂蓝健康管理集团有限公司 | Cosmetic for improving skin purification function |
-
2008
- 2008-12-31 CN CN200810233781A patent/CN101766557A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102257962A (en) * | 2011-06-09 | 2011-11-30 | 中国科学院植物研究所 | Method for obtaining banyan regeneration plants by tissue culture and culture medium thereof |
| CN102257962B (en) * | 2011-06-09 | 2012-12-26 | 中国科学院植物研究所 | Method for obtaining banyan regeneration plants by tissue culture and culture medium thereof |
| CN102836098A (en) * | 2012-09-14 | 2012-12-26 | 刘婷 | Chinese medicinal herb composition beauty essence |
| CN102895173A (en) * | 2012-10-31 | 2013-01-30 | 倪金福 | Whitening cleansing cream |
| CN104288019B (en) * | 2014-09-25 | 2016-10-26 | 江苏奇力康皮肤药业有限公司 | A kind of moisturizing Aloe glue and preparation method thereof |
| CN108272736A (en) * | 2018-04-19 | 2018-07-13 | 王风云 | A kind of toner and preparation method thereof with high activity |
| CN109771346A (en) * | 2019-03-11 | 2019-05-21 | 广东大鹏医药科技有限公司 | A kind of lily feet flower composition and its preparation and use with whitening ecchymose removing function |
| CN111973538A (en) * | 2020-07-16 | 2020-11-24 | 重庆珂蓝健康管理集团有限公司 | Cosmetic for improving skin purification function |
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Open date: 20100707 |