CN101757544A - Traditional Chinese medicine composition for treating hepatic fibrosis after hepatitis treatment - Google Patents
Traditional Chinese medicine composition for treating hepatic fibrosis after hepatitis treatment Download PDFInfo
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- CN101757544A CN101757544A CN200810154479A CN200810154479A CN101757544A CN 101757544 A CN101757544 A CN 101757544A CN 200810154479 A CN200810154479 A CN 200810154479A CN 200810154479 A CN200810154479 A CN 200810154479A CN 101757544 A CN101757544 A CN 101757544A
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Abstract
The invention belongs to the field of traditional Chinese medicines and relates to a traditional Chinese medicine composition for treating hepatic fibrosis after hepatitis treatment. The traditional Chinese medicine composition is mainly prepared from the following traditional Chinese medicine components with the weight ratio: 10-15g of rhizoma sparganii, 10-15g of Rhizoma Zedoariae, 10-15g of green tangerine orange peel, 10-15g of Common Burreed Rhizome, 10-15g of Bupleurum, 10-15g of turmeric, 10-15g of angelica, 10-15g of red paeonia, 10-15g of turtle shell and 15-25g of raw oyster. The invention has the effects of activating blood circulation to dissipate blood stasis and resolving hard lumps and has exact curative effect on hepatic fibrosis after hepatitis.
Description
Technical field
The invention belongs to the field of Chinese medicines.
Background technology
Hepatic fibrosis (hepatic fibrosis) is meant diffusivity extracellular matrix (particularly collagen) over-deposit in the liver.It is not an independently disease, but many chronic hepatic diseases all can cause hepatic fibrosis, its cause of disease is broadly divided into infectivity (chronic type b, third type and hepatitis D, blood draws parasitosis etc.), inborn errors of metabolism (hepatolenticular degeneration, hemachromatosis, α1-Kang Yidanbaimeiquefazheng etc.) and chemical metabolization defective (chronic alcoholic liver disease, chronic drug-induced liver disease) and autoimmune hepatitis, constitutional liver juice liver cirrhosis and primary sclerosing cholangitis etc.
In normal liver tissue, various cells and extracellular matrix have accurate relative scale and specific relative tertiary location very much, accurately regulate and control structure, function and metabolism state by the signal transmission between the cell, between cell and the extracellular matrix, becoming a metastable microecosystem.From dynamic viewpoint, fibroplasia is meant the synthetic increase of various extracellular matrixs, and fiber decomposes the degradation of extracellular matrix process that then is meant; The generation of hepatic fibrosis, develop and lapse to " net effect " that depends on the two.The hepatic fibrosis hypertrophy is a kind of reparation reaction of body for the liver parenchyma damage due to the acute liver injury, and too much extracellular matrix is degraded in case the cause of disease is removed, and hepatic tissue inner cell inner cell and substrate are recovered normally very much, thereby do not produce hepatic fibrosis.But the lasting or liver parenchyma inflammation necrosis repeatedly due to the chronic hepatopathy can cause a large amount of hypertrophy of fibrous connective tissue and the relative or absolute deficiency of its degrading activity, and therefore extrtacellular matrix depositions get off to form hepatic fibrosis in a large number.If hepatic fibrosis then is called liver cirrhosis simultaneously with lobules of liver structural damage (hepatic regenerative nodules).But, be difficult to both clinically well-separated because chronic hepatopathy is a successive evolution by hepatic fibrosis to liver cirrhosis.In recent years basis and clinical research show, if can give effective etiological treatment, or can directly suppress the synthetic of extracellular matrix and/or promote its degraded, and hepatic fibrosis that has then formed even early stage liver cirrhosis also can reverse.It should be the task of top priority that effective medicine is provided so.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of the hepatitis heptic fibrosis.
A kind of Chinese medicine composition for the treatment of the hepatitis heptic fibrosis mainly comprises following traditional Chinese medicine components by weight ratio: rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.
Rhizoma sparganic, Rhizoma Curcumae removing blood stasis in the side, pain in the circulation of qi promoting is as controlling the principal agent that gathers card; Radix Angelicae Sinensis blood stasis dispelling blood is supported fresh blood; Radix Paeoniae Rubra pathogenic fire purging sending down the abnormal ascending QI, the promoting the circulation of blood dissipating blood stasis; Be combined into the eliminating pathogen in the liver of nourishing blood, control the effect of the stasis of blood with auxilliary principal agent; Pericarpium Citri Reticulatae Viride, Radix Curcumae, Fructus Aurantii, Radix Bupleuri is Liver Channel QI and blood medical treatment medicine all, and Pericarpium Citri Reticulatae Viride is unclogged and readjusted irritability, and eliminating stagnation disappears stagnant; Radix Bupleuri is discongested stagnation of liver-QI, and bar reaches mechanism of qi; Radix Curcumae goes into septum pectorale, blood-activating and qi-promoting; Fructus Aurantii walks the gastral cavity abdomen, and alleviating distention in middle-JIAO relaxes and expands; Four medicines are assistant; Carapax Trionycis draws it with Radix Bupleuri, goes the side of body hard down; Concha Ostreae master trusted subordinate lump in the abdomen is hard long-pending, and two medicines are got its hard masses softening and resolving, and assistant helps softening liver Pi.Wherein, all through Liver Channel of little Radix Bupleuri, Pericarpium Citri Reticulatae Viride, Carapax Trionycis, Radix Angelicae Sinensis, all medicines of Radix Paeoniae Rubra can be messenger drug.
The present invention has blood circulation promoting and blood stasis dispelling, and the effect of hard masses softening and resolving is used for the treatment of the hepatitis heptic fibrosis and has definite curative effect.
The specific embodiment
Example 1
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 2
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Ascites very person adds the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Polyporus, each 10～15g of Poria.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 3
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Abdominal distention very person adds Radix Aucklandiae (Radix Vladimiriae), each 10～15g of Semen Arecae.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 4
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.The epistaxis person adds Pollen Typhae carbon, Colla Corii Asini, Radix Rubiae, each 10～15g of Rhizoma Imperatae.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 5
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Bitter taste, xerostomia are received, difference adds Endothelium corneum, each 10～15g of Fructus Crataegi, consumer product dredge stasis; Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 6
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Side of body patient adds Fructus Toosendan, each 10～15g of Rhizoma Corydalis.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 7
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Costalgia, gastral cavity expand and add the Radix Aucklandiae, each 10～15g of Cortex Magnoliae Officinalis, and alleviating distention in middle-JIAO is regulated the flow of vital energy.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Example 8
Rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, each 10～15g of Carapax Trionycis, Concha Ostreae 15～25g.Constipation adds Rhizoma Coptidis, Radix Scutellariae, each 5～10g of Radix Et Rhizoma Rhei, function of gallbladder promoting relieving constipation.Every day potion, the decocting extracting juice is used for the treatment of the hepatitis heptic fibrosis, one month is 1 course of treatment.
Adopt the present invention to treat hepatitis heptic fibrosis 80 examples.Male's 54 examples wherein, women's 26 examples; Minimum 17 years old of age, maximum 59 years old, average 36.5 years old; The course of disease is the shortest 1.5 years, and is the longest 13.4, average 4.8 years; Chronic active hepatitis 64 examples, early stage liver cirrhosis 16 examples; Accompany slight ascites 8 examples, companion's splenomegaly 10 examples.The clinical basic healing of criterion of therapeutical effect: subjective symptoms and positive sign disappear, and it is normal that biochemical indicators such as liver function, B ultrasonic and HA recover.Produce effects: subjective symptoms disappears, and positive sign takes a turn for the better, the more preceding improvement of liver function B ultrasonic, and it is normal that biochemical indicators such as HA recover substantially.Effectively: subjective symptoms takes a turn for the better, and positive sign is improved or be stable, and biochemical indicators such as liver function, B ultrasonic and HA improve.Invalid: as not reach effective standard or deterioration person.As a result, produce effects 24 examples, effective 42, total effective rate has reached 82.5%.Therapeutic effect is not subjected to the influence of the course of disease and age size, and improves along with the prolongation of treatment time.
Claims (8)
1. a Chinese medicine composition for the treatment of the hepatitis heptic fibrosis is characterized in that, mainly comprises following traditional Chinese medicine components by weight ratio: rhizoma sparganic, Rhizoma Curcumae, Pericarpium Citri Reticulatae Viride, Fructus Aurantii, Radix Bupleuri, Radix Curcumae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Carapax Trionycis each 10～15, Concha Ostreae 15～25.
2. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: the Rhizoma Atractylodis Macrocephalae, Rhizoma Alismatis, Polyporus, Poria each 10～15.
3. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Radix Aucklandiae (Radix Vladimiriae), Semen Arecae each 10～15.
4. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Pollen Typhae carbon, Colla Corii Asini, Radix Rubiae, Rhizoma Imperatae each 10～15.
5. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Endothelium corneum, Fructus Crataegi each 10～15.
6. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Fructus Toosendan, Rhizoma Corydalis each 10～15.
7. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: the Radix Aucklandiae, Cortex Magnoliae Officinalis 10～15.
8. the Chinese medicine composition of treatment hepatitis heptic fibrosis according to claim 1 is characterized in that, also comprises following traditional Chinese medicine components by weight ratio: Rhizoma Coptidis, Radix Scutellariae, Radix Et Rhizoma Rhei each 5～10.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810154479A CN101757544A (en) | 2008-12-24 | 2008-12-24 | Traditional Chinese medicine composition for treating hepatic fibrosis after hepatitis treatment |
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| CN200810154479A CN101757544A (en) | 2008-12-24 | 2008-12-24 | Traditional Chinese medicine composition for treating hepatic fibrosis after hepatitis treatment |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230556A (en) * | 2013-05-15 | 2013-08-07 | 周富贵 | Traditional Chinese medicine for treating cirrhosis and liver cancer and preparation method thereof |
| CN104587416A (en) * | 2015-02-17 | 2015-05-06 | 聂玮 | Traditional Chinese medicinal composition for treating early hepatocirrhosis |
| CN104826024A (en) * | 2015-05-22 | 2015-08-12 | 广西中医药大学 | Anti-hepatic fibrosis plumbagin preparation and preparation method thereof |
| CN104826019A (en) * | 2015-05-15 | 2015-08-12 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine composition for treating hepatitis B with hepatic fibrosis |
-
2008
- 2008-12-24 CN CN200810154479A patent/CN101757544A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230556A (en) * | 2013-05-15 | 2013-08-07 | 周富贵 | Traditional Chinese medicine for treating cirrhosis and liver cancer and preparation method thereof |
| CN103230556B (en) * | 2013-05-15 | 2015-09-09 | 周富贵 | A kind of Chinese medicine and preparation method thereof for the treatment of liver cirrhosis, hepatocarcinoma |
| CN104587416A (en) * | 2015-02-17 | 2015-05-06 | 聂玮 | Traditional Chinese medicinal composition for treating early hepatocirrhosis |
| CN104826019A (en) * | 2015-05-15 | 2015-08-12 | 青岛辰达生物科技有限公司 | Traditional Chinese medicine composition for treating hepatitis B with hepatic fibrosis |
| CN104826024A (en) * | 2015-05-22 | 2015-08-12 | 广西中医药大学 | Anti-hepatic fibrosis plumbagin preparation and preparation method thereof |
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Addressee: Zhongbao Pharmaceutical Co., Ltd., Tianjin Liang You Document name: Notification that Application Deemed to be Withdrawn |
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Application publication date: 20100630 |