CN101748046B - Full temperature micro volume blending incubation and hybridization instrument - Google Patents
Full temperature micro volume blending incubation and hybridization instrument Download PDFInfo
- Publication number
- CN101748046B CN101748046B CN 200910262876 CN200910262876A CN101748046B CN 101748046 B CN101748046 B CN 101748046B CN 200910262876 CN200910262876 CN 200910262876 CN 200910262876 A CN200910262876 A CN 200910262876A CN 101748046 B CN101748046 B CN 101748046B
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- Prior art keywords
- hybridization
- temperature
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- micro volume
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- 238000009396 hybridization Methods 0.000 title claims abstract description 34
- 238000002156 mixing Methods 0.000 title claims abstract description 23
- 238000011534 incubation Methods 0.000 title claims abstract description 17
- 238000010438 heat treatment Methods 0.000 claims abstract description 9
- 238000005057 refrigeration Methods 0.000 claims abstract description 8
- 239000011521 glass Substances 0.000 claims description 6
- 238000009413 insulation Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 9
- 239000000463 material Substances 0.000 abstract description 4
- 239000007791 liquid phase Substances 0.000 abstract description 3
- 238000005034 decoration Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000002086 nanomaterial Substances 0.000 description 14
- 239000007788 liquid Substances 0.000 description 5
- 239000002105 nanoparticle Substances 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000005484 gravity Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
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- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000012295 chemical reaction liquid Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000007899 nucleic acid hybridization Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000002751 oligonucleotide probe Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
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- 229910052710 silicon Inorganic materials 0.000 description 1
- 230000005476 size effect Effects 0.000 description 1
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/16—Vibrating; Shaking; Tilting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/14—Incubators; Climatic chambers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/42—Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910262876 CN101748046B (en) | 2009-12-14 | 2009-12-14 | Full temperature micro volume blending incubation and hybridization instrument |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200910262876 CN101748046B (en) | 2009-12-14 | 2009-12-14 | Full temperature micro volume blending incubation and hybridization instrument |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101748046A CN101748046A (en) | 2010-06-23 |
CN101748046B true CN101748046B (en) | 2012-08-15 |
Family
ID=42475663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200910262876 Expired - Fee Related CN101748046B (en) | 2009-12-14 | 2009-12-14 | Full temperature micro volume blending incubation and hybridization instrument |
Country Status (1)
Country | Link |
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CN (1) | CN101748046B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103992945B (en) * | 2014-05-19 | 2015-09-23 | 东南大学 | A kind of constant-temperature incubation hybrid device |
CN106872432A (en) * | 2017-03-30 | 2017-06-20 | 杭州晶格科学仪器有限公司 | A kind of fluorescence detection device and temperature control method with temperature control mechanism |
CN109486650B (en) * | 2018-09-20 | 2022-03-25 | 宁波新芝生物科技股份有限公司 | Microorganism growth curve tester |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19925154A1 (en) * | 1998-06-02 | 1999-12-09 | Kendro Lab Prod Gmbh | Controlling internal temperature of e.g. an incubator cabinet equipped with heater and coolant compressor |
CN1401760A (en) * | 2002-09-09 | 2003-03-12 | 梁朝 | Energy-saving magnetic suspension nucleic acid hybridizing furnace |
CN2727185Y (en) * | 2004-06-09 | 2005-09-21 | 李勇 | Incubation device with ice bath |
CN2789267Y (en) * | 2005-03-22 | 2006-06-21 | 肖先进 | Molecular hybridization instrument |
CN101063078A (en) * | 2007-04-20 | 2007-10-31 | 博奥生物有限公司 | Biological chip hybrid cleaning device |
CN201062262Y (en) * | 2007-06-26 | 2008-05-21 | 北京和利时系统工程股份有限公司 | Biochip hybridization instrument |
-
2009
- 2009-12-14 CN CN 200910262876 patent/CN101748046B/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19925154A1 (en) * | 1998-06-02 | 1999-12-09 | Kendro Lab Prod Gmbh | Controlling internal temperature of e.g. an incubator cabinet equipped with heater and coolant compressor |
CN1401760A (en) * | 2002-09-09 | 2003-03-12 | 梁朝 | Energy-saving magnetic suspension nucleic acid hybridizing furnace |
CN2727185Y (en) * | 2004-06-09 | 2005-09-21 | 李勇 | Incubation device with ice bath |
CN2789267Y (en) * | 2005-03-22 | 2006-06-21 | 肖先进 | Molecular hybridization instrument |
CN101063078A (en) * | 2007-04-20 | 2007-10-31 | 博奥生物有限公司 | Biological chip hybrid cleaning device |
CN201062262Y (en) * | 2007-06-26 | 2008-05-21 | 北京和利时系统工程股份有限公司 | Biochip hybridization instrument |
Also Published As
Publication number | Publication date |
---|---|
CN101748046A (en) | 2010-06-23 |
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PB01 | Publication | ||
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SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: NAIJING ZHONGKE SHENGUANG TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: SOWTHEAST UNIV. Effective date: 20141011 |
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C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 210096 NANJING, JIANGSU PROVINCE TO: 210038 NANJING, JIANGSU PROVINCE |
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TR01 | Transfer of patent right |
Effective date of registration: 20141011 Address after: Xinghe Nanjing economic and Technological Development Zone Road Qixia District of Nanjing City, Jiangsu province 210038 No. 18 Patentee after: NANJING ZHONGKE SHENGUANG TECHNOLOGY Co.,Ltd. Address before: 210096 No. four archway, Xuanwu District, Jiangsu, Nanjing 2 Patentee before: Southeast University |
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TR01 | Transfer of patent right |
Effective date of registration: 20201120 Address after: Room 201, building A1, Longgang science and Technology Park, Hengyuan Road, Nanjing Economic and Technological Development Zone, Qixia District, Nanjing City, Jiangsu Province Patentee after: Nanjing Zhongke Tongyi Technology Co.,Ltd. Address before: Xinghe Nanjing economic and Technological Development Zone Road Qixia District of Nanjing City, Jiangsu province 210038 No. 18 Patentee before: NANJING ZHONGKE SHENGUANG TECHNOLOGY Co.,Ltd. |
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TR01 | Transfer of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120815 |
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CF01 | Termination of patent right due to non-payment of annual fee |