CN101721495A

CN101721495A - Chinese herbal medicine wine for treating rheumatoid arthritis

Info

Publication number: CN101721495A
Application number: CN200810158136A
Authority: CN
Inventors: 李桂英
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-10-24
Filing date: 2008-10-24
Publication date: 2010-06-09
Anticipated expiration: 2028-10-24
Also published as: CN101721495B

Abstract

The invention provides a Chinese herbal medicine wine for treating rheumatoid arthritis, which is prepared by decocting and filtering Chinese herbal medicines of Chinese angelica, cassia bark, common monkshood mother root, himalayan teasel root, safflower, twotooth achyranthes root and the like for obtaining a medicament and further being blended with liquor. The Chinese herbal medicine wine has the advantages of significant efficacy, simple formula, easy production and low cost, and is mainly used for treating the rheumatoid arthritis and applicable to needs of most of patients.

Description

A kind of herbal wine for the treatment of rheumatic arthritis

Technical field

The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese herbal medicine medicated wine for the treatment of rheumatic arthritis.

Background technology

Rheumatic arthritis is a kind of systemic disease of the non-infectious inflammation based on joint and joint surrounding tissue by its ill reason of viewpoint of doctor trained in Western medicine, it is relevant with inherited genetic factors, autoimmune response that a lot of scholars think, doctor trained in Western medicine is not clear and definite as yet to using up to etiology and pathology at present.The traditional Chinese medical science thinks that pathogenic factor and pathogenic process have substantially: the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, and wind-cold damp pathogen impatency meridians and joint, stagnation of QI and blood may bring about pain is so cause joint swelling and pain.Ying-qi is defended the blood imbalance, disharmony of nutrient QI with defensive QI, and pathogen is taken advantage of a weak point, and causes the rheumatism outbreak.Internal organs negative and positive internal injury, the negative and positive imbalance inclined to one side Sheng occurs and declines partially, is subjected to pathogen and invades, so rheumatismal heat and cold symptom performance take place.Give birth in the phlegm-turbidity and blood stasis blood: the pathogenic factor going from the exterior into the interior, by light and weigh, cause visceral dysfunction, and the result of visceral dysfunction just produces the turbid and blood stasis of expectorant, these are exactly the touching and basic reason of refractory of the rheumatism state of an illness.

The patient who suffers from rheumatic arthritis, since patient age, sex, body constitution difference, suffered pathogenic factor difference, the reason difference of just falling ill, so the clinical symptoms that shows is successively different, but generally speaking the earliest symptom is a pain, sometimes the string pain is local acute painful sometimes.Pain is the symptom of each first appearance of patient, next the pathological changes in joint occurs, joint, somewhere, two joints, or pain, swelling, heating, distortion appear in many places joint simultaneously, and joint motion is limited, deadlock in morning (WA joint deadlock every morning), a series of symptoms such as ankylosis, the little joint of the finger of human body (toe), neck, breast, joint of lumbar vertebra, the shoulder of upper limb, elbow, joints such as the hip of wrist, lower limb, knee joint, ankle all can take place.For rheumatic arthritis treatment, be divided into generally that Western medicine alleviates pain, the pain relieving of medicine for external use relaxing muscles and tendons and activating QI and blood in the collateral.As using bigcatkin willow acid supplement and on-steroidal preparation, diminish inflammation the control active rheumatism with alleviating pain.With dog skin plaster (plaster) functions dispelling wind and clearing away cold, removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral pain relieving.Also have ten thousand clever muscles and bones cream, ZHUIFENG GAO, Herba Erodii cream etc. in addition.Because " curing the symptoms, not the disease ", and easily recurrence after the drug withdrawal are so it is generally acknowledged there is not specific drug to the treatment of rheumatic arthritis.

Summary of the invention

The object of the present invention is to provide a kind of herbal wine, this medicated wine can have been cured rheumatic arthritis preferably in the shorter course of treatment, and through clinical trial, this medicated wine is controlled the cure rate height, cures not repeatedly, has no side effect.

The present invention treats the medicated wine of rheumatic arthritis, by following bulk drugs: Radix Angelicae Sinensis 5-15 weight portion, Cortex Cinnamomi 5-15 weight portion, Radix Aconiti 5-10 weight portion, Radix Dipsaci 5-10 weight portion, Flos Carthami 5-10 weight portion, Radix Achyranthis Bidentatae 5-15 weight portion, Herba Ephedrae 10-20 weight portion, Radix Glycyrrhizae 10-20 weight portion, above-mentioned Chinese medicine is mixed the back decocting 2 times, the elimination medicinal residues, the gained medicinal liquid is blent in the 1000 weight portion 40-60 degree Chinese liquor, shaken up and promptly get medicated wine.

In the above-mentioned Chinese medicine, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.It is supporing yang that Cortex Cinnamomi is mended fire, let the fire back to its origin, and dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow is used for trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, warming the meridian and promoting blood circulation.The Radix Dipsaci invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating cures mainly aching pain in waist and back, the foot and knee being feeble, traumatic injury.Flos Carthami invigorate blood circulation latus rectum, eliminating stasis to stop pain are used for lump in the abdomen mass in the abdomen, traumatic injury.The Radix Achyranthis Bidentatae invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards is used for soreness of waist and knee joint, muscles and bones is unable.Herba Ephedrae diaphoresis cold expelling, the carbuncle of yin nature that looses, eliminating mass knot.The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity.Chinese liquor has blood circulation and channel invigorating, helps the effect of the efficacy of a drug.

When taking this medicated wine, with hot water heating and add and put brown sugar less, effect is better with medicated wine.This medicated wine has unique curative effect to rheumatic arthritis.

The specific embodiment

The fill a prescription weight portion proportioning of best each raw material of the present invention: Radix Angelicae Sinensis 9 weight portions, Cortex Cinnamomi 10 weight portions, Radix Aconiti 6 weight portions, Radix Dipsaci 6 weight portions, Flos Carthami 6 weight portions, Radix Achyranthis Bidentatae 7 weight portions, Herba Ephedrae 12 weight portions, Radix Glycyrrhizae 12 weight portions, to fry in shallow oil 2 times after the above-mentioned Chinese medicine mixing, the elimination medicinal residues are blent the gained medicinal liquid in the 1000 weight portion 40-60 degree Chinese liquor and promptly to be got medicated wine.

Process for preparing medicine of the present invention is, with the gram is unit of weight, take by weighing each medicine (Radix Angelicae Sinensis 9 weight portions by said ratio, promptly take by weighing Radix Angelicae Sinensis 9 grams, all the other are same), will mix after each medicine pulverizing, with warm fiery fried 25-30 minute, the elimination medicinal residues are blent the gained medicinal liquid in the 1000 weight portion 40-60 degree Chinese liquor and promptly to be got medicated wine.

When taking, medicated wine with hot water heating and add and put brown sugar less, can be played better effect.Take every day 3 times, early, middle and late each once, a 30mL, period in a medicine fasting raw food food.

It below is clinical observation material of the present invention.

The inventor is to 200 routine case clinical observations, wherein, male 120 examples, women 80 examples, at minimum 35 years old of age, maximum 70 years old, the course of disease was the longest 19 years, the shortest person half a year, average 6 years.The case selection is diagnosed as the patient of rheumatic arthritis according to symptom and examination in hospital.Wherein, test group 120 examples, male 80 examples, women 40 examples, at minimum 35 years old of age, maximum 70 years old, the course of disease was the longest 19.2, the shortest person half a year, average 6.2 years.Test group 80 examples, male 45 examples, women 35 examples, at minimum 36 years old of age, maximum 69 years old, the course of disease was the longest 18.8, the shortest person half a year, average 5.7 years.The course of disease of two groups of cases, degrees of symptoms etc., comprehensive average back there was no significant difference has comparability between each group.The Chinese medicinal liquor that test group adopts the present invention's medicine to make is treated, during treatment, the administrated method of test group is: with medicated wine with hot water heating and add and serve after putting brown sugar less, take every day 3 times, early, middle and late each once, a 30mL, period in a medicine fasting raw food food, every 1000ml Chinese liquor is a course of treatment, serve on 3 courses of treatment.Matched group gives homemade ibuprofen 0.4g oral, every day three times, serve on 2 months.

Two groups of cases all the 1st week, the 2nd week, the 1st month, the 2nd month are observed cardinal symptom and sign after medication.

The criterion of curative effect, the percentage scoring method that adopts Huskisson to propose, i.e. visual simulation pain scale (VAPS) is promptly used 100 millimeters straight lines, and an end is painless, and the other end is for the most painful.Patient regularly marks the degree of its pain on line in the same time of this day.In conjunction with clinical practice, curative effect is divided basic healing, produce effects, effective and invalid.The concrete standard of curative effect is as follows:

The basic healing: pain symptom disappears, and VAPS is less than 20;

Produce effects: pain symptom obviously alleviates, and VAPS is between 20-50;

Effectively: pain symptom alleviates, and VAPS is between 21-80;

Invalid: pain symptom alleviates not obvious, and VAPS is more than 80.

Curative effect situation catalog

Group	The basic healing	Produce effects	Effectively	Invalid	Total effective rate
Group	The basic healing	Produce effects	Effectively	Invalid	Total effective rate	Test group	??75	??20	??11	??14	??88.33％
Matched group	??16	??15	??29	??20	??75％	Test group	??75	??20	??11	??14	??88.33％

As can be seen from the above table, the cure rate of test group is 62.5%, and the cure rate of matched group is 20%.The cure rate of test group has been compared the significance effect with matched group.The total effective rate of test group is 88.33%, and the total effective rate of matched group is 75%.The effective percentage of test group has been compared with two contrasts the significance effect.

Healing case in the test group is paid a return visit after 1 year and is not all had recurrence.In sum, the therapeutic effect of the present invention's medicine obviously is better than matched group.

Claims

1. herbal wine for the treatment of rheumatic arthritis, it is characterized in that, it is prepared from by the following weight proportion raw material: Radix Angelicae Sinensis 5-15 weight portion, Cortex Cinnamomi 5-15 weight portion, Radix Aconiti 5-10 weight portion, Radix Dipsaci 5-10 weight portion, Flos Carthami 5-10 weight portion, Radix Achyranthis Bidentatae 5-15 weight portion, Herba Ephedrae 10-20 weight portion, Radix Glycyrrhizae 10-20 weight portion, to fry in shallow oil 2 times after the above-mentioned Chinese medicine mixing, the elimination medicinal residues are blent the gained medicinal liquid in the 1000 weight portion 40-60 degree Chinese liquor and promptly to be got medicated wine.

2. a kind of medicine that ash refers to for the treatment of according to claim 1, it is characterized in that, it is prepared from by the following weight proportion raw material: Radix Angelicae Sinensis 9 weight portions, Cortex Cinnamomi 10 weight portions, Radix Aconiti 6 weight portions, Radix Dipsaci 6 weight portions, Flos Carthami 6 weight portions, Radix Achyranthis Bidentatae 7 weight portions, Herba Ephedrae 12 weight portions, Radix Glycyrrhizae 12 weight portions, to fry in shallow oil 2 times after the above-mentioned Chinese medicine mixing, the elimination medicinal residues are blent the gained medicinal liquid in the 1000 weight portion 40-60 degree Chinese liquor and promptly to be got medicated wine.