CN101703157A - Poultry feed additive and preparation method and application thereof - Google Patents
Poultry feed additive and preparation method and application thereof Download PDFInfo
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- CN101703157A CN101703157A CN200910308231A CN200910308231A CN101703157A CN 101703157 A CN101703157 A CN 101703157A CN 200910308231 A CN200910308231 A CN 200910308231A CN 200910308231 A CN200910308231 A CN 200910308231A CN 101703157 A CN101703157 A CN 101703157A
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Abstract
The invention discloses a poultry feed additive and a preparation method and application thereof, and aims to provide the poultry feed additive used for detoxicating mycotoxin and preventing and controlling fungal infection, and the preparation method and application thereof. The feed additive comprises the following components in percentage by weight: 1 to 4 percent of clotrimazole or 1 to 3 percent of nystatin, 5 to 20 percent of malto-oligosaccharides, 5 to 12 percent of glucurolactone, 10 to 20 percent of glucomannan polymer, 20 to 40 percent of sepiolite, 0.2 to 1 percent of vitamin C and the balance of conventional feed additive auxiliary material. Different adsorbents are mixed in a proper ratio so as to contribute to improving detoxication effect. Various active components are reasonably compatible, so the feed additive has synergism, and has the effects in various aspects such as treating the fungal infection, avoiding mould damaging livestock organisms, detoxicating organisms and adsorbing the mycotoxin, and has quick response, good treatment effect and safe use when used for detoxicating the mycotoxin and preventing and controlling the fungal infection.
Description
Technical field
The present invention relates to a kind of detoxicating mycotoxin that is used for and prevent and treat livestock fodder additives of mycotic infection and its production and application simultaneously.
Background technology
In recent years, because increasing the weight of of Global Greenhouse Effect makes grain or feed be become clear day by day by the degree of mould and endotoxin contamination thereof and scope.
Mycotoxin is the secondary metabolism toxic products that is produced during growth and breeding in feed by the part mould, and mycotoxin is different from mould, and mycotoxin is the product of mould activity, only depends on naked eyes to be difficult for realizing.When you see that feed does not go mouldy as yet, a large amount of fatal mycotoxins might have wherein just been produced.According to FAO and WHO statistics, have 25% to be subjected to mycotoxin contamination in various degree approximately in the bread crop in the annual whole world.
The feed that contains mycotoxin by livestock and poultry edible after, tend to take place mycotoxin and poison.Domestic at present because the disease research that mould and mycotoxin are caused is less, often the disease wrong diagnosis that mycotoxin is caused is an infectious disease, false diagnosis causes the invalid or poor efficiency of medicine, incur loss through delay disease and control opportunity, thereby the chance of invasion is arranged for real infectious disease, cause the bigger loss of aquaculture.
Mycotoxin is except that directly making livestock and poultry poison to cause death, even more serious is that immunity function of livestock and poultry and production performance are descended, be in sub-health state for a long time, the disease that has caused many immuning failures and seriously taken place and be difficult to prevent and treat again and again produces harm by food chains such as meat, egg, milk to human health simultaneously.These serious problems do not cause the attention that people are enough as yet even exist some mistake to know now, should show great attention to this present situation.
At present,, adopt full group to add 3% glucose, treat with nystatin sheet or clotrimazole etc. to the livestock or poultry of having poisoned.But above-mentioned methods of treatment just produces effect to mycotic infection, and can not treat mycotoxin to the continuation of poultry body infringement, and the toxicity that can not toxonoid causes.
Theoretically the poison-removing method of mycotoxins in feed is had multiplely, but really can eliminate mycotoxin aborning fully and practical method is difficult to find.
At present, theoretic poison-removing method to mycotoxin mainly contains following several method:
(1) physics detoxification: reject mouldy or damaged seed, slough and contain more outer covering of a kernel of toxin or plumule, or eluriate with clear water, or by methods such as Exposure to Sunlight, radiation, heating, absorption with minimizing content of toxins or toxicity.Wherein, physisorphtion has bentonite absorption method and active carbon adsorption.The bentonite that uses in the bentonite absorption method is with the particulate clay of montmorillonite as main component, and montmorillonite belongs to 2: 1 type layer aluminosilicate quasi-minerals.Contain weanling pig and growth pig and to add 1% sodium bentonite in the daily ration of AF 922 μ g/kg, can partial offset AF to the harmful effect of growth of animal and animal blood biochemical indicator.Bentonite have certain absorption to lysine with supporting one's family.The selective adsorption capacity of active carbon adsorption is relatively poor, also can adsorb nutriment in absorbing toxin, is often lost the adsorption capacity of contratoxin in the body by the saturated back of some nutritional labeling in the feed.
(2) chemical detoxication: some mycotoxin can be destroyed degraded by the chemicals of part, as the common mouldy seed of soda lye wash of using, with ammoniacal liquor degradable part aflatoxin etc., but different chemical substances often only effectively can not be degraded to other toxin to certain toxin. have chemical substance has high residue in feed problem with the chemical method detoxification, from and produced new poisonous and harmful effect.
(3) biological detoxication: mainly contain enzymatic isolation method and microbe fermentation method, these class methods equally only have certain effect to certain toxin, and enzyme is thermo-labile, the easy inactivation of process in feed processing, and the effect of microbe fermentation method is slow.Use biological detoxication method cost higher and effect is unstable, thus in production practices still difficulty apply.
Other detoxicity method: add antioxidant, sulfur-containing amino acid, vitamin and trace element etc. in feed, alleviating the illeffects of mycotoxin, but their contratoxin do not have specificity.But the daily ration of chicken substantially all is by the preparation of feed producer, is sold to the raiser and uses there, and the raiser is difficult to the composition of control feed, and feed factory is difficult to accomplish to add amino acid etc., control the infringement of mycotoxin to poultry in order to save cost more.
In a word, though detoxification, detoxification are a lot, all have certain limitation: detoxification is not thorough, and addition is bigger, and expense is higher, destroys or adsorption feed nutrition etc.
Summary of the invention
The present invention is in order to overcome deficiency of the prior art, a kind of livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously that is used for to be provided.
Second purpose of the present invention provides a kind of preparation method that detoxicating mycotoxin is prevented and treated the livestock fodder additives of mycotic infection simultaneously that is used for.
The 3rd purpose of the present invention provides a kind of detoxicating mycotoxin that is used for and prevents and treats the livestock fodder additives of mycotic infection simultaneously and be used for the application that detoxicating mycotoxin is prevented and treated the poultry feed of mycotic infection simultaneously in preparation.
The present invention is achieved through the following technical solutions:
A kind ofly be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously, it is characterized in that consisting of of percentage by weight: clotrimazole 1-4% or nystatin 1-3%, oligomeric maltose 5%-20%, Glucurolactone 5%-12%, glucomannans polymer 10-20%, sepiolite 20-40%, vitamin C 0.2%-1%, surplus is a conventional feed additive auxiliary material.
Wherein, best group becomes: percentage clotrimazole 2% or nystatin 1.5%, oligomeric maltose 10%, Glucurolactone 10%, glucomannans polymer 15%, sepiolite 30%, vitamin C 0.2% by weight, surplus is a conventional feed additive auxiliary material.
Described conventional feed additive auxiliary material is at least a in zeolite powder, rice husk, the talcum powder.Multiple auxiliary material can be by the arbitrary proportion proportioning.
A kind ofly be used for the preparation method that detoxicating mycotoxin is prevented and treated the livestock fodder additives of mycotic infection simultaneously, it is characterized in that comprising the steps: with clotrimazole or nystatin, oligomeric maltose, Glucurolactone, the glucomannans polymer, sepiolite, vitamin C and conventional feed additive auxiliary material are respectively after pulverizing and sieving, percentage is got clotrimazole 1-4% or nystatin 1-3% by weight, oligomeric maltose 5%-20%, Glucurolactone 5%-12%, glucomannans polymer 10-20%, sepiolite 20-40%, vitamin C 0.2%-1%, surplus is a conventional feed additive auxiliary material, mix, promptly make and originally be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
A kind of detoxicating mycotoxin that is used for is prevented and treated the livestock fodder additives of mycotic infection simultaneously and is used for the application that detoxicating mycotoxin is prevented and treated the poultry feed of mycotic infection simultaneously in preparation.
The present invention has following technique effect:
In the feed addictive of the present invention, clotrimazole claims agisten again, new broad-spectrum antifungal medicine for chemical synthesis, belong to bacteriostatic, multiple pathogenic fungus all there is inhibitory action. antibacterial action mechanism changes the permeability of endochylema film for optionally combining with the lipid of fungi endochylema film, and produces bacteriostasis, fungi is difficult for producing drug resistance to this product. and toxicity is little, and bad reaction is very rare.
Nystatin: the effect of nystatin tool broad-spectrum antifungal, to antibacterial activity height such as aspergillus flavus, aspergillus parasiticus, Aspergillus ochraceus, fusarium moniliformes.
The present invention has utilized the effect of the absorbing mycotoxin of sepiolite.Sepiolite is a kind of hydrous magnesium silicate clay mineral, has largest specific surface area in the nonmetallic mineral (reaching as high as 900m2/g) and unique inside pore passage structure, is the strongest clay mineral of adsorption capacity of generally acknowledging.The absorption property of sepiolite brilliance, rheological property and high security can be widely used in the feed industry.Compare with other loam mould adsorbents (if you would take off stone, kaolin, medical stone etc.) product, the maximum characteristics of meerschaum adsorbent product are: sepiolite absorption property shelter has the hat of clay mineral, be far superior to unselected clay mineral institutes such as montmorillonite, kaolin, sepiolite possesses superpower absorption property.Sepiolite has the advantage of clay mineral adsorbent simultaneously: high security, high stability.Avirulence, with other material generation chemical reactions, the Chemical Physics stable performance does not have high security and stability.
The glucomannans polymer: it is a class novel antigens active material that extracts from yeast cell wall, has the porous characteristics, and its surface area is bigger, and the pH value scope internal stability height different helps absorbing mycotoxin quickly and efficiently.By in the body of pig, poultry, milk cow and external evidence, it can adsorb dissimilar mycotoxins effectively, and addition is low, thereby is a kind of application mycotoxin antidote more widely.
Oligomeric maltose adds in the feed, can effectively keep the colony balance in the enteron aisle, suppresses growth and the breeding of harmful bacterium, thereby avoids the injury of mould to the livestock and poultry body.
Glucurolactone is for strengthening the hepatoprotective agent of liver detoxification function, when hepatocellular injury, the function of detoxification of liver descends, it is interior under the effect of enzyme that Glucurolactone enters body, become glucuronic acid, can combine with the poisonous substance that contains hydroxyl or carboxyl, form the glucuronide conjugate of nontoxic or low toxicity, from urine, discharge.
Vitamin C can be alleviated the toxic action of bacteriotoxin to body effectively, can neutralize and destroy bacterial endotoxin, and the production of energy enhancing antibody, increases the resistance of body to disease; Simultaneously, also have function of detoxification, improve the activity of mixed-function oxidase, promote the hydroxylation of medicine or poisonous substance, thereby play detoxication.
The present invention carries out suitable proportioning with dissimilar adsorbents, helps to improve detoxification efficiency.
Feed addictive of the present invention is by the reasonable compatibility of each active ingredient, has synergy, from the treatment mycotic infection, avoid mould that many-sides such as the injury of livestock and poultry body, body detoxifcation, absorbing mycotoxin are played a role, the detoxification and the control livestock and poultry mycotic infection instant effect that are used for mycotoxin, good effect, safe in utilization.
The specific embodiment
Below in conjunction with specific embodiment to the detailed description of the invention.
Clotrimazole, nystatin, oligomeric maltose, Glucurolactone, glucomannans polymer, sepiolite, vitamin C, zeolite powder, rice husk, talcum powder is standby behind pulverizing and mistake 80 mesh sieves respectively.
Embodiment 1:
Get clotrimazole 20g, oligomeric maltose 100g, Glucurolactone 50g, glucomannans polymer 100g, sepiolite 400g, vitamin C 2g, talcum powder 328g mixes, and promptly makes to be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 2
Get clotrimazole 40g, oligomeric maltose 200g, Glucurolactone 50g, glucomannans polymer 200g, sepiolite 200g, vitamin C 10g, rice husk 300g mixes, and promptly makes to be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 3
Get clotrimazole 10g, oligomeric maltose 50g, Glucurolactone 100g, glucomannans polymer 100g, sepiolite 400g, vitamin C 5g, zeolite powder 335g mixes, and promptly makes to be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 4
Get nystatin 10g, oligomeric maltose 150g, Glucurolactone 100g, glucomannans polymer 200g, sepiolite 250g, vitamin C 4g, rice husk 286g mixes, and promptly makes to be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 5
Get nystatin 20g, oligomeric maltose 80g, Glucurolactone 100g, glucomannans polymer 150g, sepiolite 350g, vitamin C 6g, talcum powder 200g, rice husk 94g, mix, promptly make and be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 6
Get nystatin 15g, oligomeric maltose 100g, Glucurolactone 100g, glucomannans polymer 150g, sepiolite 300g, vitamin C 2g, zeolite powder 230g, rice husk 103g, mix, promptly make and be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Embodiment 7
Get clotrimazole 20g, oligomeric maltose 100g, Glucurolactone 100g, glucomannans polymer 150g, sepiolite 300g, vitamin C 2g, talcum powder 200g, rice husk 128g, mix, promptly make and be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
Feed addictive of the present invention can be used for detoxicating mycotoxin and the control mycotic infection of poultry.Below be that example is tested feed addictive of the present invention with commercial meat bird in the poultry.
Clinical report
One, check experiment
1, test one
(1) trial drug:
The feed addictive of the embodiment of the invention 6 preparations, our unit's development;
(main component: endotoxin adsorbent-montmorillonite), the Tianjin Shengshilai Science and Technology Co., Ltd produces in mould poison spirit.
(2) test method
The chicken house that 9000 commercial meat birds are arranged, 3000 chickens of every hen house, 3 hen house generation mycotoxicosis under identical raising condition, are changed feed.Wherein, the 1st hen house uses the product treatment of the embodiment of the invention 6, using method: the feed addictive of the 100g embodiment of the invention 6 preparations is joined in the 200kg feed, and whole day is fed, logotype 4 days; The 2nd hen house uses mould poison spirit treatment, and using method: the mould malicious spirit of 100g is used for the 200kg feed, and whole day is fed, logotype 4 days; The 3rd hen house do not treated.
(3) result of the test
After the treatment beginning, the record situation of change, treatment results is as shown in table 1.
A l hen house to the stopped death in 3 days, and the death rate is 0.5%; The 2nd hen house stops death in the time of the 5th day, the death rate is 1.9%; The 3rd hen house to the stops death substantially in the time of 8 days, the death rate is 6.3%.
(4) analysis of experiments
As can be seen, when mycotoxicosis took place, the embodiment of the invention 6 use groups did not compare with using the medicine group from table l, and the death rate is low, differs 5.8%, through t check, significant difference; The product of the embodiment of the invention 6 and mould malicious miraculous cure thing control group compare, and the death rate is low, through t check, significant difference.
Table 1
| Group | Deposit the number (only) of raising chickens | Death toll (only) | The death rate |
| The embodiment of the invention 6 product experimental group | ??3000 | ??15 | ??0.5％ |
| The clever control group of mould poison | ??3000 | ??56 | ??1.9％ |
| Medication control group not | ??3000 | ??189 | ??6.3％ |
2, test two
(1) trial drug:
The feed addictive of the embodiment of the invention 7 preparations, our unit's development;
(main component: endotoxin adsorbent-montmorillonite), the Tianjin Shengshilai Science and Technology Co., Ltd produces in mould poison spirit.
(2) test method
The chicken house that 9000 commercial meat birds are arranged, 3000 chickens of every hen house, 3 hen house generation mycotoxicosis under identical raising condition, are changed feed.Wherein, the 1st hen house uses the product treatment of the embodiment of the invention 7, using method: the feed addictive of the 100g embodiment of the invention 7 preparations is joined in the 200kg feed, and whole day is fed, logotype 4 days; The 2nd hen house uses mould poison spirit treatment, and using method: the mould malicious spirit of 100g is used for the 200kg feed, and whole day is fed, logotype 4 days; The 3rd hen house do not treated.
(3) result of the test
After the treatment beginning, the record situation of change, treatment results is as shown in table 2.
A l hen house to the stopped death in 3 days, and the death rate is 0.5%; The 2nd hen house stops death in the time of the 5th day, the death rate is 1.9%; The 3rd hen house to the stops death substantially in the time of 8 days, the death rate is 6.3%.
Table 2:
| Hen house | Deposit the number (only) of raising chickens | Death toll (only) | The death rate |
| 1 | ??3000 | ??15 | ??0.5％ |
| 2 | ??3000 | ??57 | ??1.9％ |
| 3 | ??3000 | ??189 | ??6.3％ |
(4) analysis of experiments
As can be seen from Table 2, when mycotoxicosis took place, the embodiment of the invention 7 use groups did not compare with using the medicine group, and the death rate is low, differs 5.8%, through t check, significant difference; The product of the embodiment of the invention 7 and mould malicious miraculous cure thing control group compare, and the death rate is low, through t check, significant difference.
Two, use-case
In May, 2009,10000 fryer generation lassitudes that Baodi two meat sold on the market chicken houses in Tianjin are raised, the decline of searching for food, diarrhoea, the dead rising are dissected and the feed observation analysis according to clinical symptoms, case, and tentative diagnosis is that mycotoxin is poisoned.
Clinical symptoms:
In nosotoxic early stage, paralysis appears in sick chicken, and quantity increases gradually, expiratory dyspnea is dehisced to stretch neck and is breathed, and is short of breath, the sick chicken that has also shows drowsiness, and appetite is given up and cut off, becomes thin, thirsty desire increases, diarrhoea, and row is white, green or black also have the ight soil that does not digest feed.If esophageal mucosa membrane is contaminated by mould, visible dysphagia.Later stage, symptom such as that chicken is mainly is fluffy and disorderly, matt by hair, diarrhea, feed intake are few, poor growth.
Pathological change:
The acute chicken dehydration of dying of illness; Tracheorrhagia has the brief summary of yellow-white caseous necrosis on tracheae, lungs, the air bag; The liver enlargement, matter is crisp; Splenomegaly, softness, the tangent plane structure is unclear; The kidney enlargement, gray purple; Duodenal hemorrhage; Muscular stomach and glandular stomach intersection are hemorrhage, ulcer, erosion; Intestinal mucosa has blood spots, have and come off.
The chronic chicken that dies of illness shows as the necrosis of the visible white wheat bran sample of crop wall; The bursa of farbricius and thymic weight alleviate, atrophy, interstitial edema; The liver enlargement, color and luster is pale thin out, and the blutpunkte is arranged, and the liver hand is pinched and is resembled rubber, is commonly called as " rubber liver "; Cholecystectasia; The kidney gout has lithate deposition (piebald kidney); Chest is subcutaneous and muscle is common hemorrhage; Sometimes fibrinous pericarditis and perihepatitis appear in secondary Mycoplasma or Escherichia coli.According to the characteristics of mycotoxicosis, we have chosen the product treatment that the embodiment of the invention 6 is made.The product 100g that embodiment 6 is produced is used for feed 200kg, and whole day is fed.
Use after 3 days, symptom improves.Death in the 4th day stops.
Claims (5)
1. one kind is used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously, it is characterized in that consisting of of percentage by weight: clotrimazole 1-4% or nystatin 1-3%, oligomeric maltose 5%-20%, Glucurolactone 5%-12%, glucomannans polymer 10-20%, sepiolite 20-40%, vitamin C 0.2%-1%, surplus is a conventional feed additive auxiliary material.
2. according to claim 1ly be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously, it is characterized in that consisting of of percentage by weight: clotrimazole 2% or nystatin 1.5%, oligomeric maltose 10%, Glucurolactone 10%, glucomannans polymer 15%, sepiolite 30%, vitamin C 0.2%, surplus are conventional feed additive auxiliary material.
3. according to claim 1ly be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously, it is characterized in that consisting of of percentage by weight: clotrimazole 2% or nystatin 1.5%, oligomeric maltose 10%, Glucurolactone 10%, glucomannans polymer 15%, sepiolite 30%, vitamin C 0.2%, surplus are conventional feed additive auxiliary material.
4. a claim 1 is described is used for the preparation method that detoxicating mycotoxin is prevented and treated the livestock fodder additives of mycotic infection simultaneously, it is characterized in that comprising the steps: with clotrimazole or nystatin, oligomeric maltose, Glucurolactone, the glucomannans polymer, sepiolite, vitamin C and conventional feed additive auxiliary material are respectively after pulverizing and sieving, percentage is got clotrimazole 1-4% or nystatin 1-3% by weight, oligomeric maltose 5%-20%, Glucurolactone 5%-12%, glucomannans polymer 10-20%, sepiolite 20-40%, vitamin C 0.2%-1%, the conventional feed additive auxiliary material of surplus, mix, promptly make and be used for the livestock fodder additives that detoxicating mycotoxin is prevented and treated mycotic infection simultaneously.
5. each described detoxicating mycotoxin that is used for is prevented and treated the livestock fodder additives of mycotic infection simultaneously and is used for the application that detoxicating mycotoxin is prevented and treated the poultry feed of mycotic infection simultaneously in preparation among the claim 1-3.
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| CN200910308231A CN101703157A (en) | 2009-10-13 | 2009-10-13 | Poultry feed additive and preparation method and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200910308231A CN101703157A (en) | 2009-10-13 | 2009-10-13 | Poultry feed additive and preparation method and application thereof |
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| CN101703157A true CN101703157A (en) | 2010-05-12 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116001A (en) * | 2013-04-27 | 2014-10-29 | 天津瑞贝特科技发展有限公司 | Feed additive capable of reducing mycotoxin and preparation method thereof |
| CN113367248A (en) * | 2021-06-17 | 2021-09-10 | 江苏省家禽科学研究所 | Feed, preparation method thereof and feeding method of laying hens |
| CN113367249A (en) * | 2021-06-17 | 2021-09-10 | 江苏省家禽科学研究所 | Additive and application thereof |
| GB2610895B (en) * | 2021-05-21 | 2023-12-06 | Anpario Plc | Composition for use in the treatment and/or prevention of mycotoxic disease |
| CN117243292A (en) * | 2023-08-23 | 2023-12-19 | 江苏省家禽科学研究所 | Additive, antibacterial feed, antibacterial method and application |
-
2009
- 2009-10-13 CN CN200910308231A patent/CN101703157A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116001A (en) * | 2013-04-27 | 2014-10-29 | 天津瑞贝特科技发展有限公司 | Feed additive capable of reducing mycotoxin and preparation method thereof |
| GB2610895B (en) * | 2021-05-21 | 2023-12-06 | Anpario Plc | Composition for use in the treatment and/or prevention of mycotoxic disease |
| CN113367248A (en) * | 2021-06-17 | 2021-09-10 | 江苏省家禽科学研究所 | Feed, preparation method thereof and feeding method of laying hens |
| CN113367249A (en) * | 2021-06-17 | 2021-09-10 | 江苏省家禽科学研究所 | Additive and application thereof |
| CN113367249B (en) * | 2021-06-17 | 2022-09-06 | 江苏省家禽科学研究所 | Additive and application thereof |
| CN117243292A (en) * | 2023-08-23 | 2023-12-19 | 江苏省家禽科学研究所 | Additive, antibacterial feed, antibacterial method and application |
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Application publication date: 20100512 |