CN101700292B - Traditional Chinese medicine composite for curing lymphatic tuberculosis - Google Patents

Traditional Chinese medicine composite for curing lymphatic tuberculosis Download PDF

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CN101700292B
CN101700292B CN2009102349389A CN200910234938A CN101700292B CN 101700292 B CN101700292 B CN 101700292B CN 2009102349389 A CN2009102349389 A CN 2009102349389A CN 200910234938 A CN200910234938 A CN 200910234938A CN 101700292 B CN101700292 B CN 101700292B
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CN101700292A (en
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申丽
吴永海
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Yangzhou University
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Abstract

The invention relates to a traditional Chinese medicine composite, in particular to a traditional Chinese medicine composite for curing lymphatic tuberculosis which is prepared by the raw medicinal materials of blister beetle, cinnabaris, camphol, white pepper, croton and peach seed. Compared with the prior art, the traditional Chinese medicine composite in the invention has the advantages of short treatment course, obvious curative effect, convenience and safety and low cost.

Description

The scrofulous Chinese medicine composition of a kind of treatment
Technical field
The present invention relates to a kind of Chinese medicine composition, the concrete scrofulous Chinese medicine composition of a kind of treatment that relates to.
Background technology
The lymphoid tuberculosis traditional Chinese medical science is called " sucutaneous nodule ", " scrofula ", also has " expectorant scrofula ", " string scrofula ", " overlapping scrofula " and multiple titles such as " sabre and beadstring scrofulaes " on the document, how because of anxiety and rage, disposition is not smooth, and irritability is held phlegm-fire under the arm and stagnated in liver and gall two warps, from the beginning of tuberculosis such as bean, one piece or three, five pieces is not waited, and scurries life gradually, and color of the leather is constant, hard by it, push away actively, do not make cold and heat, unconsciously pain, with the passing of time then little have the pain and swelling, it is motionless that its nuclear pushes away.Lymph tuberculosis mainly refers to betide chronic, the specific infection disease of lymph nodes such as cervical region, oxter, groin, and the patient mostly is child and adolescence, and minority is secondary to lung or bronchial tuberculosis.Modern medicine thinks that lymphoid tuberculosis is by the lymph node chronic inflammation due to the mycobacterium tuberculosis infection, so be also referred to as tuberculous lymphadenitis, is the more common disease of surgery.
At present, western medical treatment generally adopts the tuberculosis therapeutic regimen, as 2HRZE/4HR (H: isoniazid; R: rifampicin; Z: pyrazinamide; E: ethambutol), 3HRZS (E)/9HR (H: isoniazid, R: rifampicin, S: streptomycin, Z: pyrazinamide, E: ethambutol), 2DL 2ZS/4DL 2(D: Dipasic, L: rifapentine, Z: pyrazinamide, S: streptomycin) etc.But but antituberculotics mostly makes and organizes the inaccessible effective bacteriocidal concentration of Chinese medicine concentration because of being difficult to penetrate pathological tissues, can not realize effectively bactericidal action; Or make treatment failure because of untoward reaction such as liver function injury.Operative treatment cooperates antituberculosis drugs treat, can improve curative effect to a certain extent, but the preoperative and postoperative administration time is of a specified duration, and the course of treatment is longer, in case drug withdrawal, normal easily recurrence, expense is also expensive.Therapy of combining Chinese and Western medicine can improve symptom to a certain extent, improve curative effect, the toxic and side effects of antagonism chemotherapeutics, but still have situations such as treatment is loaded down with trivial details, the course of treatment is long.
Summary of the invention
The technical problem to be solved in the present invention is: a kind of short treating period is provided, and lymphoid tuberculosis medicine evident in efficacy, convenient and safe, cheap overcomes the weak point that prior art is treated.
Scheme of the present invention is:
The scrofulous Chinese medicine composition of a kind of treatment is made up of following crude drug: Mylabris, Cinnabaris, Borneolum Syntheticum, Radix orixae japonicae, Fructus Crotonis, Semen Persicae.
The weight proportion of above-mentioned traditional Chinese medicinal composition raw materials is: 5~20 parts of Mylabris, 10~30 parts in Cinnabaris, 5~20 parts of Borneolum Syntheticums, 50~70 parts of Radix orixae japonicaes, 50~100 parts of Fructus Crotonis, 5~20 parts in Semen Persicae.
Chinese medicine composition via intranasal application of the present invention administration, because of the nasal membrane area is big, rich blood vessel, the medicine abnormal smells from the patient is absorbed rapidly and the through tuberculose focus treatment of the quick conduction of meridians lymphoid tuberculosis in body.
This medicine claims standard by above-mentioned prescription prescription consumption, pulverizes into powder, with Mel and even, transfers to mix the big piller of Semen Glycines.
In the prescription of the present invention:
Mylabris: the nature and flavor suffering, cold, poisonous.Return large intestine, small intestinal, liver, kidney channel.Counteracting toxic substances, removing blood stasis.Malignant boil is controlled in external, stubborn dermatitis, facial hemiparalysis, throat moth; The scrofula, lyssodexis controlled for oral administration.
Cinnabaris: nature and flavor are sweet, and cold is poisonous.The GUIXIN warp.Calm the nerves arresting convulsion, tomorrow, detoxifcation.Control demented, the palpitation with fear, vexed, the insomnia: dizzy, blurred vision, toxic swelling, skin infection, scabies.
Borneolum Syntheticum: nature and flavor suffering, hardship, cold.Go into the heart, lung meridian.Logical all keys, the stagnated fire of loosing, removing nebula makes eye bright, reducing swelling and alleviating pain.Control the apoplexy locked mouth, the calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is the nebula film also, enterobiasis.
Radix orixae japonicae: nature and flavor suffering, heat.Return stomach, large intestine channel.Warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, expectorant, detoxifcation.Control the cold-phlegm food stagnation, coldness and pain in the epigastrium, regurgitation, the vomiting clear water is had loose bowels cold-dysentery.And separate bromatotoxin.
Fructus Crotonis: the nature and flavor suffering, heat, poisonous.Return stomach, large intestine channel.Rush down cold amassing, orifice opening, by expectorant, row water, parasite killing.Control cold long-pending stagnating, the distension and fullness of the chest and abdomen shoot, abdominal mass due to blood stasis, accumulation of phlegm in the hypochondrium, dysentery, edema, acute throat trouble is controlled in external, sore throat, malignant boil scabies.
Semen Persicae: nature and flavor hardship, sweet, flat.GUIXIN, liver, large intestine channel.Blood stasis removing and clots absorbing is moisturized laxation.Control amenorrhea , mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Mel: nature and flavor are sweet, and are flat.Return lung, board, large intestine channel.Invigorating middle warmer is moisturized, pain relieving, detoxifcation.Control the xeropulmonary cough, the dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup is separated the Aconitum carmichjaelii Debx. poison.
Chinese medicine composition of the present invention compared with prior art has short treating period, and is evident in efficacy, convenient and safe, the advantage that cost is low.
The specific embodiment
Compositing formula consumption weighting raw materials is pulverized into powder according to the present invention.Get an amount of medicated powder, drip 2~3 of Mel, transfer with cotton swab to mix the big piller of Semen Glycines, fill in (man left and woman right) in the nostril.Once in a week, each four hours, four times was a course of treatment.In the medication process, skid off from the nostril for preventing pill or snotter, can lie low bed or medication tampon are lived the nostril mouth.Only produce slighter reaction after the drug use, promptly the nasal mucosa excitement bubbles sometimes, can smear a small amount of anti-inflammatory ointment in nostril after each medication finishes.The minority image has laxativeness and bottleneck throat drying.Fasting cock, Cyprinus carpio, pig head meat, beef, egg etc. during the medication.Use this Drug therapy, have do not have an injection, do not take medicine, motionless operation, the characteristics of not being in hospital, each phase lymphoid tuberculosis is all had significant curative effect, acute and chronic tonsillitis, pharyngolaryngitis etc. are also had good curative effect.Clinical in addition this medicine of also finding also has special efficacy to metrocystosis and hysteromyoma.
Case selects MethodsThe cases enrolled to be the lymphoid tuberculosis patient who makes a definite diagnosis, totally 48 people.Be divided into two groups at random, experimental group is 24 examples, wherein male 14 examples, women 10 examples, year mean age (34.2 ± 23.1); Matched group 24 examples, male 15 examples, women 9 examples, year mean age (35.4 ± 24.5).Two groups of patients no difference of science of statistics aspect age, sex composition.
The clinical manifestation lymphoid tuberculosis can be divided into initial stage, mid-term, three periods of late period according to ill process and symptom.In early days, lymphoid tuberculosis such as finger size, one piece or several pieces is not waited, color of the leather is constant, by it is solid, push away active, not bitterly.In mid-term, the volume of pathological changes lymph node increases gradually, and activity reduces gradually with the surrounding tissue adhesion.Be fused into mutually between the lump that has and conspire to create piece, what push away is motionless, feels pain gradually.Gradually change dark red as color of the leather, by slight fever and little person that has the fluctuation, be interior formed pus.With low grade fever, night sweat, anorexia, agitation, fatigue etc.In late period, cheesy thin pus is flowed out in the diabrosis voluntarily of lymphoid tuberculosis part abscess, accompanies worn-out cotton wadding for quilt sample thing.Wound is moving under water property (ghost), and is purple dark all around, and this heals, and that is burst, and forms sinus tract, prolongedly do not heal.The lymphoid tuberculosis sinus tract can have a plurality of by-paths, stretches to all directions, and what have reaches several centimetres deeply, and this kind of is also referred to as ulceration-type clinically.Whole body is with hectic fever, hectic fever due to YIN-deficiency, cough, night sweat, or the few magnificent color of face, tired mind, dizziness, insomnia, or abdominal distention, just sugar, become thin, indigestion and loss of appetite etc.
Matched group: initial stages 15 example, mid-terms 7 example, late periods 2 example.Experimental group: initial stages 13 example, mid-terms 8 example, late periods 3 example.Two groups of comparing differences do not have significance.
It is the 2HRZE/4HR scheme that the Therapeutic Method matched group gives the oral anti-tuberculous drug thing.2 months reinforcement phases, 4 months continuation phases.H: isoniazid 0.6g, the next day 1 time; R: rifampicin 0.6g, the next day 1 time; Z: pyrazinamide 1.5g, the next day 1 time; E: ethambutol 1000g, the next day 1 time.Formed abscess or fistula person, pus, flushing are taken out in the part, and antituberculotics external application or injection are handled.
Experimental group adopts the treatment of medicine plug nose, has formed abscess or fistula person, and after pus, flushing were taken out in the part, medicine external application or injection were handled.
Curative effect is judged healing: lump dissipation or ulcer, sinus tract healing, and General Symptoms disappears; Produce effects: abscess is significantly dwindled, and ulcer, sinus tract heal substantially, and symptom is most of to disappear; Effectively: abscess is obviously dwindled and be there is no the diabrosis tendency; Ulcer, the more preceding improvement of sinus tract, General Symptoms improves; Invalid: lump does not disappear, the sinus tract disunion, and General Symptoms does not improve.
Curative effect relatively between table 1 liang group
Figure G2009102349389D00041
As can be seen from Table 1, experimental group 1 month is compared cure rate significant difference (P<0.05) with matched group; Experimental group 2 months is compared with matched group, and cure rate difference is (P<0.01) extremely significantly.It can also be seen that from table 1 experimental group is cured and obviously shortened the course of treatment, 2 months cure rate of experimental group is 58.3%, differs obvious with 2 months cure rate of matched group 16.7%.

Claims (1)

1. the scrofulous Chinese medicine composition of treatment is characterized in that its crude drug weight proportion is: 5 ~ 20 parts of Mylabris, 10 ~ 30 parts in Cinnabaris, 5 ~ 20 parts of Borneolum Syntheticums, 50 ~ 70 parts of Radix orixae japonicaes, 50 ~ 100 parts of Fructus Crotonis, 5 ~ 20 parts in Semen Persicae; The crude drug of above-mentioned formula ratio is pulverized into powder, drip the Mel accent and mix pill.
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CN110090248A (en) * 2019-05-27 2019-08-06 吴后义 A kind of mass dissipating and swelling eliminating, blood-activating analgetic receive nose medicine pill and preparation method thereof

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1132641A (en) * 1995-12-08 1996-10-09 张志明 Novel traditional Chinese medicine for treating scrofula
CN1166404C (en) * 2003-02-19 2004-09-15 姚明波 Medicine for resisting tuberculosis and preparation method
CN1237992C (en) * 2004-01-15 2006-01-25 金德成 Tuber culosis treating Chinese medicine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1132641A (en) * 1995-12-08 1996-10-09 张志明 Novel traditional Chinese medicine for treating scrofula
CN1166404C (en) * 2003-02-19 2004-09-15 姚明波 Medicine for resisting tuberculosis and preparation method
CN1237992C (en) * 2004-01-15 2006-01-25 金德成 Tuber culosis treating Chinese medicine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
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雍东播.中西医结合治疗颈淋巴结核临床效果观察.《实用中西医结合临床》.2009,第9卷(第4期),全文. *

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