CN102133338B - Yellow-purple-white-red soup used for curing ulcerative colitis - Google Patents

Abstract

The invention relates to the field of medicine formulas, in particular to yellow-purple-white-red soup used for curing ulcerative colitis, which is prepared by adopting 8-12% of coptis chinensis, 8-11% of amur corktree bark, 9-14% of raidx astragali, 8-12% of radix arnebiae seu lithospermi, 8-11% of rhizoma bletillae, 7-9% of radix angelicae, 6-9% of halloysitum rubrum, 7-10% of leonurus, 7-10% of hairyvein agrimony, 4-7% of fructus psoraleae, 3-5% of myrobalan, 3-6% of liquorice and 1-3% of pepper as raw materials according to weight percent, adding water in the raw materials for dipping, decocting, and then filtering slag, thereby obtaining filtrate. The soup has the beneficial effects of being low in cost, efficient in curing ulcerative colitis, free of toxic and side effects, and suitable for curing initial ulcerative colitis, chronic recurring type ulcerative colitis, chronic continuous type ulcerative colitis and the like.

Description

The yellow purple Bai Chitang that is used for ulcerative colitis

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of yellow purple Bai Chitang that is used for ulcerative colitis.

Background technology

Ulcerative colitis is a kind of cause of disease rectum still not fully aware of and colon chronic nonspecific inflammation property disease.Pathological changes mainly is limited to big intestinal mucosa and tela submucosa.Clinical manifestation is diarrhoea, mucopurulent bloody stool, stomachache.State of an illness weight does not wait, and is the chronic course of disease of outbreak repeatedly more.Primary disease belongs to disease scopes such as the traditional Chinese medical science alleged " hemorrhoidal hamorrhage ", " intestinal is warded off ", " chronic dysentery with frequent relapse ".The traditional Chinese medical science thinks mostly primary disease is damp and hot, epidemic disease is malicious, in the evil Yong Sai intestinal of cold-damp, the vim and vigour knot of fighting mutually with it, conduction mistake department, the fat network is impaired, coagulation of QI-blood turn to lipidemia and under the dysentery red in vain.Clinical no effect method treatment mainly is an anti symptom treatment, stresses rest, diet and nutrition; The application of pain relieving, infection, glucocorticoid and immunosuppressant, therapeutic purposes are control acute attacks, keep alleviation; Prevent and treat complication, brought great misery and financial burden to the patient.

Summary of the invention

The object of the invention is exactly in order to overcome above-mentioned existing technical deficiency; A kind of yellow purple Bai Chitang that is used for ulcerative colitis is provided; Cost is low, treats ulcerative colitis curative effect height, has no side effect, and is applicable to just hair style, chronic recurrence type, chronic lasting type etc.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of yellow purple Bai Chitang that is used for ulcerative colitis, its technical characterictic are that adopting Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Arnebiae (Radix Lithospermi), Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Halloysitum Rubrum, Herba Leonuri, Herba Agrimoniae, Fructus Psoraleae, Fructus Chebulae, Radix Glycyrrhizae, Fructus Piperis is that raw material is soaked in water, and removes slag to such an extent that filtrate after decocting; Raw material is formed: Rhizoma Coptidis 8～12%, Cortex Phellodendri 8～11%, the Radix Astragali 9～14%, Radix Arnebiae (Radix Lithospermi) 8～12%; The Radix Angelicae Dahuricae 7～9%, Pseudobulbus Bletillae (Rhizoma Bletillae) 8～11%, Halloysitum Rubrum 6～9%; Herba Leonuri 7～10%, Herba Agrimoniae 7～10%, Fructus Psoraleae 4～7%; The Fructus Chebulae 3～5%, Radix Glycyrrhizae 3～6%, Fructus Piperis 1～3%.

The invention has the beneficial effects as follows that cost is low, treat ulcerative colitis curative effect height, have no side effect, be applicable to just hair style, chronic recurrence type, chronic lasting type etc.

The specific embodiment

Below in conjunction with embodiment the present invention is done further description:

Embodiment 1:

Adopting Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Arnebiae (Radix Lithospermi), Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Halloysitum Rubrum, Herba Leonuri, Herba Agrimoniae, Fructus Psoraleae, Fructus Chebulae, Radix Glycyrrhizae, Fructus Piperis is that feedstock production forms.Its component (weight %) is Rhizoma Coptidis 10, Cortex Phellodendri 10, the Radix Astragali 10, Radix Arnebiae (Radix Lithospermi) 10, Pseudobulbus Bletillae (Rhizoma Bletillae) 11, the Radix Angelicae Dahuricae 8, Halloysitum Rubrum 8, Herba Leonuri 8, Herba Agrimoniae 9, Fructus Psoraleae 6, Fructus Chebulae 4, Radix Glycyrrhizae 4, Fructus Piperis 2 for every pair.Getting above-mentioned 13 flavor raw material gross weights is 146 grams, at room temperature 13 flavor Chinese herbal medicine is added water to 1100～1200ml, soaks about 5 hours; The water boil slow fire of useing force then decocts to about 90 minutes, removes slag to such an extent that filtrate about 300ml, adds water 400ml again; Fried in shallow oil again 50 minutes, remove slag filtrating 100ml, twice altogether about medicinal liquid 400ml; Shake up 1 dose of every day.About 38 ℃ of medicinal liquids, emptying defecation before getting 100ml and sleeping is every night got left lateral position, raises the about 10cm of buttocks, with aseptic disposable No. 14 catheters insertion anal 12cm retention enema.Surplus 300ml medicinal liquid divide every day 2 times oral, sooner or later about each (medicine) being taken before meal 150ml.Retention enema adds the purple Bai Chitang of oral Huang and disappears to the clinical symptoms sign, and it is all to consolidate the curative effect application 1 again.

Principal agent Rhizoma Coptidis of the present invention all has obvious inhibitory action to dysentery bacterium, bordetella pertussis, Bacillus typhi, tuberculosis, staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae and Candida albicans.Influenza A virus, Influenza B virus etc. all there is obvious inhibitory action, leptospira and infusorian are all had killing action.No matter in vivo or external leukocyte phagocytosis in the enhancing canine blood arranged all.Nature and flavor are bitter, cold, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Has heat clearing and damp drying, the function of eliminating fire and detoxication.Be used for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, acute bacillary dysentery, acute gastroenteritis, haematemesis, blood nosebleed, pain furuncle infections etc.Cortex Phellodendri has antibacterial, strengthens leukocyte phagocytic function in the blood, and the effect of coronary artery dilator has protective effect to make it should not be broken to platelet, alleviates hyperemia, effects such as blood sugar lowering.Nature and flavor are bitter, cold, have heat-clearing and toxic substances removing, and the function of pathogenic fire purging dampness cures mainly acute bacillary dysentery, acute enteritis, icterohepatitis, aphtha, rheumatic arthritis, urinary system infection, seminal emission, leucorrhea etc.The Radix Astragali can make the expansion of coronary vasodilator and renal blood vessels, the expansion of whole body peripheral vessel, and the skin blood circulation is freely contained, and brings high blood pressure down, and can strengthen myocardial contraction, and the heart of depletion is had cardiotonic.Blood glucose is descended, diuresis and sedation are arranged.Bacteriostasis and Rhizoma Coptidis, Cortex Phellodendri are identical.Sweet, the tepor of nature and flavor has invigorating QI to consolidate the body surface resistance, the function of holder skin ulcer granulation promoting.Cure mainly weak spontaneous perspiration, chronic diarrhea, proctoptosis, uterine prolapse, body is impractical swollen, chronic ulcer, open sore part disunion of a specified duration is burst for a long time and is not held back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, diabetes etc.The Radix Arnebiae (Radix Lithospermi) decoct has demulcent refrigeration function, and heart is had appreciable stimulating action, and dermatophytes etc. is had inhibitory action.Nature and flavor are sweet, salty, cold, GUIXIN, Liver Channel.Have removing heat from blood, invigorate blood circulation, the function of detoxifcation rash is used for the heat in blood poison and contains, and macule is purple black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire etc.The Pseudobulbus Bletillae (Rhizoma Bletillae) haemostatic effect is remarkable, and nature and flavor are bitter, sweet, puckery, are slightly cold, and returns lung, liver, stomach warp.Have astringing to arrest bleeding, the function of detumescence and promoting granulation is used for spitting of blood, spits blood traumatic hemorrhage, sore swollen toxin, chapped skin, hemoptysis of pulmonary tuberculosis, ulcer haemorrhage.Radix Angelicae Dahuricae nature and flavor are hot, warm, return stomach, large intestine, lung meridian, have diffusing wind dehumidifying, understand things pain-stopping, and the function of detumescence and apocenosis is used for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Halloysitum Rubrum has adsorption, the poisonous substance that can adsorb in the digestive tract for oral administration; Can adsorb inflammatory exudate, make inflammation be able to alleviate, gastrointestinal hemorrhage are had anastalsis.Its nature and flavor are sweet, sour, puckery, warm, return stomach, large intestine channel.Function with astringing intestine to stop diarrhea, hemostasis, promoting tissue regeneration and ulcer healing.Be used for the chronic diarrhea chronic dysentery, it is hemorrhage to defecate, bleeding not during menses, external treatment ulcer being unable to heal etc.The Herba Leonuri nature and flavor are bitter, hot, be slightly cold, and return liver, pericardium channel.Have promoting blood flow to regulate menstruation, the function of inducing diuresis to remove edema is used for menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria, acute nephritis edema.The Herba Agrimoniae nature and flavor are bitter, puckery, flat, GUIXIN, Liver Channel.Has astringing to arrest bleeding, dysentery relieving, antidotal function.Be used for spitting of blood, spit blood, metrostaxis, malaria is taken off the power impairment caused by overstrain, carbuncle sore tumefacting virus etc.The Fructus Psoraleae nature and flavor are hot, bitter, warm, return kidney, spleen channel.Have the kidney warming and help resistance, improving inspiration by invigorating kidney-QI, the antidiarrheal function is used for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, and has loose bowels just before dawn etc.Fructus Chebulae's nature and flavor are bitter, sour, puckery, flat, return lung, large intestine channel.Have astringing intestine to stop diarrhea and astringe the lung, the function of pathogenic fire reducing sore-throat relieving is used for the chronic diarrhea chronic dysentery, the proctoptosis of having blood in stool, and the deficiency of the lung is breathed with cough, and chronic cough is more than, the pharyngalgia hoarseness.The Radix Glycyrrhizae nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the function of coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.The Fructus Piperis nature and flavor are hot, hot, return stomach, large intestine channel.Be used for gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration.The ingenious prescription of 13 flavor Chinese herbal medicine, the mutual coordinative role of medicine is played the ulcerative colitis specially good effect altogether.

But each raw material of the present invention also blended embodiment of the listed ratio of according to the form below (percentage by weight) is realized.Its processing technique is identical with embodiment 1.

Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Shandong Province Wendeng Central Hospital, Weihai City is done further detailed description to the present invention:

Clinical data: from July, 2005 to 2010 year December, 58 examples according to the clinical symptoms sign, and are combined x line barium meal or fiberscopy, be diagnosed as ulcerative colitis 58 routine patients; Man's 28 examples, women 30 examples, 14～73 years old age; First hair style 24 examples, chronic recurrence type 25 examples, chronic lasting type 9 examples.Extent of disease: proctitis 14 examples, proctosigmoiditis 17 examples, scorching 15 examples of left hemicolon, popularity or close colitis 12 examples.Light-duty 16 examples of the course of disease, heavy 18 examples, medium-sized 24 examples.

Diagnostic criteria: " internal medicine " the 7th edition according to Lu Zaiying, Zhong Nanshan chief editor is diagnosed as patients of ulcerative colitis.

Therapeutic Method: every day, 1 dose of branch 2 times was oral, and every day is each oral 150ml on an empty stomach sooner or later, and retention enema 100ml uses 40 days every night, and it is all to consolidate the curative effect application 1 again.

The therapeutic evaluation standard:

With reference to " the disease of tcm diagnosis criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's promulgation, produce effects: patient's stomachache after the medication, diarrhoea; The mycopus hemafecia disappears, and the outer clinical manifestation symptom and sign of intestinal disappears, and x line barium meal or fiberscopy are normal; Effectively, patient's stomachache after the medication, diarrhoea obviously alleviates; A little mucopurulent bloody stool is arranged, and the outer clinical manifestation symptom and sign of intestinal is alleviated; Invalid; Clinical symptoms signs such as patient's stomachache is suffered from diarrhoea after the medication, mucopurulent bloody stool and x line barium meal or fiber enteric cavity spectroscopy do not have change, and it effectively is total effective rate that produce effects adds.

Therapeutic outcome:

Use the present invention to be used for yellow purple Bai Chitang 58 examples of ulcerative colitis, produce effects 43 examples account for 74.1%; Effective 13 examples account for 22.4%; Invalid 2 examples account for 5.5%.Total effective 56 people, effective percentage 96.5%.

Claims (1)

1. yellow purple Bai Chitang who is used for ulcerative colitis, its technical characterictic be, adopting Rhizoma Coptidis, Cortex Phellodendri, the Radix Astragali, Radix Arnebiae (Radix Lithospermi), Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Halloysitum Rubrum, Herba Leonuri, Herba Agrimoniae, Fructus Psoraleae, Fructus Chebulae, Radix Glycyrrhizae, Fructus Piperis is that raw material is soaked in water, remove slag after decocting filtrating; Raw material is formed: Rhizoma Coptidis 8～12%, Cortex Phellodendri 8～11%, the Radix Astragali 9～14%, Radix Arnebiae (Radix Lithospermi) 8～12%; The Radix Angelicae Dahuricae 7～9%, Pseudobulbus Bletillae (Rhizoma Bletillae) 8～11%, Halloysitum Rubrum 6～9%; Herba Leonuri 7～10%, Herba Agrimoniae 7～10%, Fructus Psoraleae 4～7%; The Fructus Chebulae 3～5%, Radix Glycyrrhizae 3～6%, Fructus Piperis 1～3%.