CN101698011B - Medicine for treating epidemic diarrhea of livestock and poultry - Google Patents
Medicine for treating epidemic diarrhea of livestock and poultry Download PDFInfo
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- CN101698011B CN101698011B CN2009102235284A CN200910223528A CN101698011B CN 101698011 B CN101698011 B CN 101698011B CN 2009102235284 A CN2009102235284 A CN 2009102235284A CN 200910223528 A CN200910223528 A CN 200910223528A CN 101698011 B CN101698011 B CN 101698011B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for treating epidemic diarrhea of livestock and poultry, which is a pure traditional Chinese medicine preparation prepared from various traditional Chinese medicine materials in certain weight proportions. The invention has good medicinal synergy effect and strong effect of killing bacteria or viruses causing the epidemic diarrhea of livestock and poultry, and can quickly enhance the body resistance of the livestock and poultry, prevent dehydration and exhaustion, promote recovery, remove heat from the blood and relieve diarrhea, clear away heat and toxic material, strengthen the spleen and stimulate the appetite, and ensure the treatment effect.
Description
Technical field
The present invention relates to the veterinary and use medicine, a kind of specifically veterinary drug for the treatment of epidemic diarrhea of livestock and poultry.
Background technology
Animal husbandry is the basic industry concerning food security in China and economic development.Livestock and poultry breeding industry is one of major industry of China's animal husbandry development.Greatly develop the scale livestock and poultry breeding industry, become just the enrich people important industry on road of shop, the crossbeam of provoking increasing peasant income gradually.The effect of livestock and poultry breeding industry in developing rural economy more and more paid attention to by governments at all levels, is listed in pillar industry in many places, becomes the important source of farmers' income.Yet normal easily the generation with diarrhoea of poultry is the disease of cardinal symptom, and universality exists in the raiser of various places.Epidemic diarrhea of livestock and poultry divides two kinds of bacterial infection and viral infections.Bacterial infection is by normal HUANGBAI(sic) dysentery, paratyphoid fever, swine dysentery and the piglet red dysentery etc. that cause such as escherichia coli, Salmonella, dysentery bacterium, bacillus pyocyaneus, clostridieum welchii; Viral infection: transmissible gastroenteritis of swine, epidemic diarrhea, rotavirus disease etc. all can cause piglet diarrhea.The main harm of epidemic diarrhea is to cause body dehydration and electrolyte disturbance rapidly, and then influences the activity of enzyme, hinders normal physiological activity, cause serious dysbolismus, cause anoxia, acidosis, make the vital movement of body be in the edge of collapse, directly cause depleted dead.Epidemic diarrhea is propagated rapidly, can involve peripheral plant in a few days, causes serious economy loss to aquaculture.To treat diarrhoea dialectically, can not see just to rush down and end, see just to rush down and mend, can not merely carry out symptomatic treatment, be at causing that diarrheal protopathy is because of implementing the etiological treatment measure.Treatment diarrheal technical essential key is bowel relieving system ferment, fluid infusion heart tonifying, is also noted that simultaneously and adjusts archenteric flora and recuperating gastrointestinal tract function.
Present domestic employing Sulfamethoxazole, amikacin, ciprofloxacin, ceftiofur sodium wait treats this disease.This cause of disease is all responsive to above chemical drugs, but toxic and side effects is big, and carcinogenic teratogenesis is in various degree arranged.The Ministry of Agriculture makes the industry standard (NY5029-2001) of " pollution-free food-Carnis Sus domestica ", has stipulated organoleptic indicator, physical and chemical index, microbiological indicator of nuisanceless Carnis Sus domestica etc.
Summary of the invention
Purpose of the present invention just provides a kind of good effect, short treating period, consumption is few, cost is low, residual few treatment diarrheal pure Chinese medicinal preparation medicine.Is the epoch at center now with back to nature with life sciences, and directional steerings that some developed countries propose from synthetics are sought the medicine for the treatment of at the natural Chinese medicine medicine.So we take active action, again through clinical trial for many years, go out prescription with pure Chinese medicine extraction effective ingredient, repeatedly small quantities of demonstration test, show according to available data: evident in efficacy, treating both the principal and secondary aspects of a disease, safely, have no side effect, noresidue is favored by numerous raisers deeply, help improving the physique of the nation people, for vast breeding enterprise escorts.
The present invention be directed to the pathogeny of epidemic diarrhea of livestock and poultry: due to illness poison, pathogenic bacteria, coccidiosis, change in weather, feedstuff are changed or stimulating factors such as feed mold, destroy animal intestinal mucosa and microvillus system, cause digesting mould system disorders simultaneously, microecosystem is unbalance or destruction, these factors are permeated body fluid in a large number in enteric cavity, the diarrhoea that causes having loose bowels, and dehydration is become thin, depleted dead pathogeny is chosen and is had good synergistic medicine and carry out the compatibility preparation.Trade name of the present invention " Fructus Mume diarrhoea is stopped injection ", prescription of the present invention are to form by following materials of weight proportions is refining: Fructus Mume 6-16 part, Radix Pulsatillae 5-15 part, Herba Patriniae 5-15 part, Rhizoma Atractylodis 4-15 part.
Fang Yi: Fructus Mume is sour and astringent, and the function astringing intestine to stop diarrhea ends the chronic dysentery chronic diarrhea, and sour in the mouth promotes the production of body fluid and replenishes body fluid nutrition, promote the pituitary hormone secretion, activate pancreatic function, thereby improve the state of organism endocrine system, organism metabolism with useful adjusting, is corrected electrolyte imbalance and recovered gastrointestinal road microecosystem.According to pharmacological evaluation, the Fructus Mume antiviral also all has inhibitory action to escherichia coli, dysentery bacterium, bacillus pyocyaneus, clostridieum welchii, salmonella etc., is treatment enteritis, the just first-selected good medicine of dysentery pus and blood.Radix Pulsatillae heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery can be gone into the blood system intestine toxic material clearing, for controlling the good medicine of toxic-heat and blood stasis and hygropyretic dysentery.Assistant makes Herba Patriniae and Rhizoma Atractylodis.Herba Patriniae is controlled the scorchingly hot stasis of blood and stagnates, diarrhoea dysentery; The promoting the circulation of blood of Rhizoma Atractylodis dampness removing, spleen benefiting and stimulating the appetite.
All medicine compatibilities, the drug effect Synergistic, the treatment livestock and poultry diarrhea, necrotic enteritis, evident in efficacy.Curative effect to epidemic diarrhea of livestock and poultry is better than most antibiotics and antiviral drugs.
Specific implementation method:
The present invention can be prepared into powder, oral liquid, granule, aqueous injection, wherein with aqueous injection treatment directly, rapidly, should deposit.
The injection that is used for the treatment of the epidemic diarrhea of livestock and poultry disease, trade name " Fructus Mume diarrhoea is stopped injection " and other antibiotic therapy test: Fructus Mume diarrhoea is stopped injection by per kilogram of body weight 0.1ml, intramuscular injection logotype 3 days; Sulfamethoxazole per kilogram of body weight 0.1-0.5ml, intramuscular injection is 5 days continuously; Amikacin per kilogram 5-10mg, every day 2 times, intramuscular injection logotype 5 days; Ciprofloxacin lactate per kilogram of body weight domestic animal 2.5mg, poultry 5mg, every day 2 times, intramuscular injection logotype 5 days; Ceftiofur sodium per kilogram of body weight 3-5mg, intramuscular injection logotype 5 days.
Duration of test: test is unified feeding and management with positive pig.
Criterion: clinical symptom disappearance, diet recover normal.
Result of the test:
Therapeutic effect compares:
| Grouping | The test number | Cure number | The produce effects number | Death toll | Cure rate (%) |
| Fructus Mume diarrhoea is stopped injection | 3560 | .3352 | 208 | 0 | 94.16 |
| Sulfamethoxazole | 16 | 14 | 1 | 1 | 87.5 |
| Ciprofloxacin lactate | 19 | 16 | 2 | 1 | 84.21 |
| Amikacin | 22 | 19 | 2 | 1 | 86.36 |
| Ceftiofur sodium | 18 | 16 | 2 | 0 | 88.89 |
| Matched group | 5 | 1 | 2 | 2 | 20 |
Clinical trial certificate: experiment effect obviously is better than other medicine, can substitute other similar drug, and side effect is little, and cure rate height, meat do not have the melancholy of commodity inspection, helps improving the overall quality of the population, and help animal husbandry and develop in a healthy way,
Innovative point:
1, according to motherland's Chinese medicine theory, in conjunction with knowledge such as modern Chinese medicine, reasonable compatibility cooperation potentiation is set up prescription and is determined most preferred dosage form.
2, according to infective pathogen, directly select medicine, from natural goods, extract anti-epidemic diarrhea of livestock and poultry active substance, with strong points.
3, according to clinical symptoms, from the dynamic change of molecular biology horizontal adjustment body related immune competent cell and cytokine, careful to the basic mechanism of this treatment of diseases, effect is remarkable.
4, by research to pharmacokinetics, selected the dosage form that the most suitable body absorbs, be optimal treatment approach and Therapeutic Method at type.
5, this product is a pure Chinese medicinal preparation, does not contain any antibiotic, chemical hormone etc., and noresidue has no side effect, and is safe, is the environmental type preparation.
Claims (1)
1. a medicine for the treatment of epidemic diarrhea of livestock and poultry is characterized in that its component is Fructus Mume, the Radix Pulsatillae, Herba Patriniae, Rhizoma Atractylodis, and its described composition weight proportioning is Fructus Mume 6-16 part, Radix Pulsatillae 5-15 part, Herba Patriniae 5-15 part, Rhizoma Atractylodis 4-15 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102235284A CN101698011B (en) | 2009-11-23 | 2009-11-23 | Medicine for treating epidemic diarrhea of livestock and poultry |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102235284A CN101698011B (en) | 2009-11-23 | 2009-11-23 | Medicine for treating epidemic diarrhea of livestock and poultry |
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| Publication Number | Publication Date |
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| CN101698011A CN101698011A (en) | 2010-04-28 |
| CN101698011B true CN101698011B (en) | 2011-11-30 |
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| CN2009102235284A Expired - Fee Related CN101698011B (en) | 2009-11-23 | 2009-11-23 | Medicine for treating epidemic diarrhea of livestock and poultry |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102488767B (en) * | 2011-12-27 | 2013-12-25 | 张朝晖 | Compound composition for treating bacterial diarrhoea of livestock and poultry |
| CN102600282B (en) * | 2012-04-10 | 2013-11-27 | 中国农业科学院兰州畜牧与兽药研究所 | Medicament for treating cold and deficiency type calf diarrhea and preparation method thereof |
| CN103919882A (en) * | 2013-05-16 | 2014-07-16 | 黎秋萍 | Chinese herbal medicine and food for treating chronic diarrhea |
| CN104383081B (en) * | 2014-12-05 | 2016-09-21 | 河南科技学院 | A kind of for treating the Chinese medicine preparation that diarrhea of pigs is sick |
| CN107334878A (en) * | 2017-07-14 | 2017-11-10 | 中国农业科学院兰州畜牧与兽药研究所 | It is a kind of to be used to treat Chinese medicine composition of piglet necrotic enteritis and preparation method thereof caused by C.perfringens |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002927A (en) * | 2007-01-25 | 2007-07-25 | 潘金火 | Traditional Chinese medicine capsule for treating chronic ulcerosa colitis, its component and preparing method |
| CN101579408A (en) * | 2008-05-13 | 2009-11-18 | 天津生机集团股份有限公司 | Chinese medicine powder for preventing and treating white diarrhea for baby pigs and preparation method thereof |
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2009
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002927A (en) * | 2007-01-25 | 2007-07-25 | 潘金火 | Traditional Chinese medicine capsule for treating chronic ulcerosa colitis, its component and preparing method |
| CN101579408A (en) * | 2008-05-13 | 2009-11-18 | 天津生机集团股份有限公司 | Chinese medicine powder for preventing and treating white diarrhea for baby pigs and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 王春成.加味附子薏苡败酱散合并锡类散灌肠治疗慢性溃疡性结肠炎86例临床观察.《光明中医》.2009,第24卷(第7期),1354-1355. * |
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