CN101692822A - New application of lupeol - Google Patents
New application of lupeol Download PDFInfo
- Publication number
- CN101692822A CN101692822A CN200910180616A CN200910180616A CN101692822A CN 101692822 A CN101692822 A CN 101692822A CN 200910180616 A CN200910180616 A CN 200910180616A CN 200910180616 A CN200910180616 A CN 200910180616A CN 101692822 A CN101692822 A CN 101692822A
- Authority
- CN
- China
- Prior art keywords
- lupeol
- emulsifier
- synergist
- solubilizer
- bleeding agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a botanical acaricides applied to preventing mites on industrial crops such as fruit trees, vegetables and the like as well as a preparation method and new application thereof. The botanical acaricides is prepared from lupeol adding with surfactant, emulsifier, penetrant, synergist and the like, and has the characteristics of high efficiency, low toxicity, low residue, environment friendliness and the like.
Description
Technical field
The present invention relates to the new purposes of lupeol, particularly the new purposes of lupeol in the preparation plant acaricide.
Background technology
Lupeol (Lupeol) another name Fagarasterol, molecular formula C
30H
50O molecular weight 426.7174.Phytophagous mites is the important pest in the agricultural production, and it has a very wide distribution, and the harm host is many, and it is big that area takes place, and medicine resistance ability is strong, and is serious and restive to the loss that agricultural production causes.But still there be not the application report of lupeol in the preparation plant acaricide in the existing document; Still do not have at present a kind of good with environment compatibility, to the harmonious miticide of mammalian safe.
Summary of the invention
The new purposes that the objective of the invention is to open lupeol; Another object of the present invention is to the new purposes of open lupeol in preparation plant resource miticide.
The present invention seeks to be achieved through the following technical solutions:
The application of lupeol in the preparation plant acaricide.Mite extremely of the present invention can be to kill the female one-tenth mite of Tetranychus cinnabarinus.Lupeol of the present invention adds conventional auxiliary material, according to common process, makes various forms of miticides, for example missible oil, suspending agent, pulvis, spray etc.
Prepare plant with the organic solvent lixiviate---chemical composition in the Inula britannica chinensis, according to extraction and chromatographic theory knowledge, chemical composition is divided into different material segments, and extract is by the separation of separation chromatography post, purifying active substance, and the pure active substance that obtains is accredited as lupeol through GC/MS; In the process of separation and purification material, follow the tracks of biological activity determination, active substance---lupeol has acaricidal activity to the laboratory test proof; From Singma company buy the pure product of standard---lupeol has acaricidal activity.
Lupeol miticide of the present invention is with the lupeol dissolution with solvents, can selectively add the dissolving of solubilizer, synergist, emulsifier, bleeding agent promotion lupeol therein, promptly can be used for mite extremely.
Among the acaricidal preparation method, solvent is selected from a kind of in water, ethanol, methyl alcohol, acetone, cyclohexanone, toluene, dimethylbenzene, benzinum, petroleum aromatic, the purified petroleum benzin; Solubilizer be neopelex, Potassium dodecylbenzenesulfonate, polysorbate, polyethylene glycol, sorbierite polyoxy ether, lignosulfonates, tea withered, take any in the Chinese honey locust; Synergist is any in Tea Saponin, 2-C1C6H4-N=OCH3SCH3, methylenedioxy benzene derivative, 6-vinyl capraldehyde, the Octachlorodipropyl Ether; Emulsifier is any in C15~17H31~37COONa, odium stearate, lauryl sodium sulfate, N-domiphen, APEO, polyethenoxy ether, paraoctyl phenol APEO, aliphatic alcohol polyethenoxy base ether, aliphatic acid polyethenoxy base ester, the alkylaryl sulfonates, can utilize the HLB value to select emulsifier, the HLB value obtains the good missible oil of emulsifiability between 15-18; Bleeding agent is any in emulsifier BP, azone, the triphen phosphorus.
The component of this missible oil is: lupeol 20%~50%, solubilizer 50%~20%, emulsifier 10%, synergist 10%, bleeding agent 10%. Preferred lupeol 50%, solubilizer 20%, emulsifier 10%, synergist 10%, bleeding agent 10%; Lupeol 40%, solubilizer 30%, emulsifier 10%, synergist 10%, bleeding agent 10% or lupeol 30%, solubilizer 40%, emulsifier 10%, synergist 10%, bleeding agent 10%; Lupeol 20%, solubilizer 50%, emulsifier 10%, synergist 10%, bleeding agent 10%.Adopt spray pattern control herbivore mite, it is 2mg/ml that the pure lupeol concentration of mite biological activity test missible oil is killed in the laboratory.
The invention provides a kind of and environment compatibility good, to the novel harmonious miticide of mammalian safe, the comprehensive regulation of ecological long term growth, human beings'health and evil mite is all had profound significance.Compare with traditional agricultural chemicals, the present invention has following characteristics and advantage: 1, lupeol is general at occurring in nature, content is big, can become well to exploit natural resources; 2, fat-soluble characteristics do not cause pesticide injury, toxic residue to mammalian safe, to people and animals, ecological environment security; 3, carry out synthetic easily, very help carrying out suitability for industrialized production; 4, in conjunction with other effectively kill acaricidal composition in the preparation type plant, pharmaceutical mixture can further increase effective acaricidal action.
Following experimental example and embodiment are used to further specify but are not limited to the present invention.
Experimental example
With the lupeol petroleum ether dissolution, add emulsifier tween-80, according to lupeol 50%, solubilizer 20%, emulsifier 10%, synergist 10%, bleeding agent 10%.Experimental result sees the following form:
Table 1 lupeol is to the biologically active (24h, FAO method) of the female one-tenth mite of Tetranychus cinnabarinus
Table 2 lupeol is to the bioactive gradient (24h, FAO method) of the female one-tenth mite of Tetranychus cinnabarinus
Annotate: lowercase alphabet shows that the F value less than 0.05, has significant difference among the figure.
The result proves that lupeol of the present invention has significant contact toxicity to the female adult worm of Tetranychus cinnabarinus.
Following embodiment all can realize the beneficial effect of experimental example of the present invention.
Embodiment
Embodiment 1
Lupeol 50%, solubilizer 20%, emulsifier 10%, synergist 10%, bleeding agent 10% are got above-mentioned raw materials and are made missible oil according to common process, adopt spray pattern control herbivore mite.
Embodiment 2
Lupeol 40%, solubilizer 30%, emulsifier 10%, synergist 10%, bleeding agent 10% are got above-mentioned raw materials and are made suspending agent according to common process, adopt spray pattern control herbivore mite.
Embodiment 3
Lupeol 30%, solubilizer 40%, emulsifier 10%, synergist 10%, bleeding agent 10% are got above-mentioned raw materials and are made pulvis according to common process, adopt the spraying mode to prevent and treat the herbivore mite.
Embodiment 4
Lupeol 20%, solubilizer 50%, emulsifier 10%, synergist 10%, bleeding agent 10% are got above-mentioned raw materials and are made spray according to common process, adopt spray pattern control herbivore mite.
Claims (13)
1. the application of lupeol in the preparation plant acaricide.
2. application as claimed in claim 1 is characterized in that described mite extremely is to kill the female one-tenth mite of Tetranychus cinnabarinus.
3. application as claimed in claim 1 is characterized in that described miticide is that lupeol adds solubilizer, synergist, emulsifier and/or suspending agent, bleeding agent auxiliary material therein.Among the acaricidal preparation method, solvent is selected from a kind of in water, ethanol, methyl alcohol, acetone, cyclohexanone, toluene, dimethylbenzene, benzinum, petroleum aromatic, the purified petroleum benzin; Solubilizer be neopelex, Potassium dodecylbenzenesulfonate, polysorbate, polyethylene glycol, sorbierite polyoxy ether, lignosulfonates, tea withered, take any in the Chinese honey locust; Synergist is any in Tea Saponin, 2-C1C6H4-N=OCH3SCH3, methylenedioxy benzene derivative, 6-vinyl capraldehyde, the Octachlorodipropyl Ether; Emulsifier is any in C15~17H31~37COONa, odium stearate, lauryl sodium sulfate, N-domiphen, APEO, polyethenoxy ether, paraoctyl phenol APEO, aliphatic alcohol polyethenoxy base ether, aliphatic acid polyethenoxy base ester, the alkylaryl sulfonates; Bleeding agent is any in emulsifier BP, azone, the triphen phosphorus.
4. an acaricidal cream is characterized in that the component of this missible oil is: lupeol 20%~50%, solubilizer 50%~20%, emulsifier 10%, synergist 10%, bleeding agent 10%.
5. the described acaricidal cream of claim 4 is characterized in that the component of this missible oil is: lupeol 50%, solubilizer 20%, emulsifier 10%, synergist 10%, bleeding agent 10%.
6. acaricidal cream as claimed in claim 4 is characterized in that the component of this missible oil is: lupeol 40%, solubilizer 30%, emulsifier 10%, synergist 10%, bleeding agent 10%.
7. acaricidal cream as claimed in claim 4 is characterized in that the component of this missible oil is: lupeol 30%, solubilizer 40%, emulsifier 10%, synergist 10%, bleeding agent 10%.
8. acaricidal cream as claimed in claim 4 is characterized in that the component of this missible oil is: lupeol 20%, solubilizer 50%, emulsifier 10%, synergist 10%, bleeding agent 10%.
9. the application of lupeol as claimed in claim 1 or 2 in the preparation miticide.
10. solubilizer as claimed in claim 3, synergist, emulsifier and/or suspending agent, the application of bleeding agent in the preparation miticide.
11. the application of lupeol as claimed in claim 4 in the preparation miticide.
12. as the application of the described lupeol of claim 5-8 in the preparation miticide.
13. the application of lupeol in the preparation miticide farm chemical.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101806160A CN101692822B (en) | 2009-10-27 | 2009-10-27 | New application of lupeol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009101806160A CN101692822B (en) | 2009-10-27 | 2009-10-27 | New application of lupeol |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101692822A true CN101692822A (en) | 2010-04-14 |
CN101692822B CN101692822B (en) | 2012-07-25 |
Family
ID=42091851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009101806160A Expired - Fee Related CN101692822B (en) | 2009-10-27 | 2009-10-27 | New application of lupeol |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101692822B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113383785A (en) * | 2021-06-18 | 2021-09-14 | 中国农业科学院郑州果树研究所 | Application of betulin in preparation of aphicide and aphicide |
WO2021213483A1 (en) * | 2020-04-24 | 2021-10-28 | 珠海岐微生物科技有限公司 | Application of compounds in controlling or killing mites |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100466911C (en) * | 2006-05-30 | 2009-03-11 | 北京农学院 | Wikstroemia chamedaphne Meissn.vegetative acaricides and method for making same |
-
2009
- 2009-10-27 CN CN2009101806160A patent/CN101692822B/en not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021213483A1 (en) * | 2020-04-24 | 2021-10-28 | 珠海岐微生物科技有限公司 | Application of compounds in controlling or killing mites |
CN115607555A (en) * | 2020-04-24 | 2023-01-17 | 珠海岐微生物科技有限公司 | Application of compound in inhibiting or killing acarid |
CN115607555B (en) * | 2020-04-24 | 2024-04-19 | 广州岐微生物医药科技有限公司 | Use of compounds for inhibiting or killing mites |
CN113383785A (en) * | 2021-06-18 | 2021-09-14 | 中国农业科学院郑州果树研究所 | Application of betulin in preparation of aphicide and aphicide |
CN113383785B (en) * | 2021-06-18 | 2022-07-01 | 中国农业科学院郑州果树研究所 | Application of betulin in preparation of aphicide and aphicide |
Also Published As
Publication number | Publication date |
---|---|
CN101692822B (en) | 2012-07-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102283258A (en) | Plant protecting agent for plant source and preparation method thereof | |
CN101703077B (en) | Nimbin film-spreading oil solution | |
CN101731216A (en) | Methyl linoleate acaricide and preparation method therof | |
CN104255815A (en) | Preparation method of botanical insecticide | |
CN103271100B (en) | Camphor fruit extract provided with activity resistant to crop pathogenic fungus, as well as preparation method and application of camphor fruit extract | |
CN103262847B (en) | Biogenic pesticide containing xanthoxylin and abamectin and preparation method thereof | |
CN102067834A (en) | Linoleic acid miticide and preparation method thereof | |
CN101692822B (en) | New application of lupeol | |
CN101692811A (en) | New application of ethyl palmitate | |
CN101731215A (en) | Taraxeryl acetate miticide and method for preparing same | |
CN103355326A (en) | High-efficiency pesticide composition | |
CN104996423A (en) | Application of ethyl oleate and ethyl oleate acaricide | |
CN100531569C (en) | Novel use of methyl palmitate | |
CN101869107A (en) | Scopoletin lactone plant miticide and purposes thereof | |
CN101869103A (en) | Plant miticide of squalene and applications thereof | |
CN101692821A (en) | New application of stigmasterol | |
CN1647644A (en) | Natural pyrethrin cream preparation | |
CN101743961A (en) | Alpha-amyrin acaricide and preparation method thereof | |
CN101731212A (en) | Beta-amyrin acaricide and preparation method thereof | |
CN107897217A (en) | A kind of natural volatile mosquito driving and killing agent of plant source property and preparation method thereof | |
CN102273470B (en) | Daucosterol plant miticide and purpose thereof | |
CN102067835A (en) | 4-pentylbenzoyl chloride miticide and preparation method thereof | |
CN108113929A (en) | A kind of mosquito-expelling and antipruritic compound essential oil of pure plant | |
CN104642407A (en) | Environmental protection plant source pesticide | |
Zhang et al. | Bio-activity of Lavandula angustifolia Mill. essential oil against Spodoptera litura (Fabricius). |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120725 Termination date: 20131027 |