CN101692817A - Pesticide composition and application thereof - Google Patents

Abstract

The invention relates to a pesticide composition, wherein effective components comprise buprofezin and flonicamid. The pesticide composition has the obvious synergy effect on the prevention and control of pests on agriculture, particularly on resistant homoptera pests. By using in the field, the invention can reduce the dosage in the field as well as environmental pollution and pesticide residues and delay the development speed of the pesticide resistance of the pests.

Description

A kind of Pesticidal combination and application thereof

Technical field

The present invention relates to a kind of composition pesticide and application thereof, be specially a kind of insecticides that contains Buprofezin, and be applied to prevent and treat the resistant insect on the plant.

Background technology

In agricultural production, breeding amount is big, the tangible insect of generation overlap, and is very fast as the resistance generation speed of insects such as plant hopper, aphid, aleyrodid, trialeurodes vaporariorum, and the speed of exploitation new varieties of pesticides does not catch up with the resistance development speed of insect far away.So, the composite of agricultural chemicals just seems very valuable, and particularly the different medicament of the mechanism of action is composite, can improve drug effect, and the development of delaying drug resistance, to prolong the service life of effective ingredient.

Rice hoppers: rice fulgorid is one of representative of homoptera pest, is migratory pest common on the paddy rice, and it directly stings suction rice juice, makes growth retardation, and the rice clump is agglomerating withered when serious, even the dead stalk lodging in full field.According to the result of rice fulgorid resistance monitoring, along with constantly migrating, the resistance of rice fulgorid constantly rises, and this has brought great difficulty for the control of rice fulgorid.Chang Yong Imidacloprid, Mobucin etc. used the rice fulgorid poor effect separately in the past.

Aleyrodid: aleyrodid is the important pests of China vegetables, melon and fruit, and the whole nation that distributes is the primary pest of northern greenhouse gardening crop, comprises Bemisia tabaci and trialeurodes vaporariorum.With adult with nymph is intensive sucks water at vacuum side of blade, secrete a large amount of honeydews, cause the generation of sooty mould, but transmitted virus also.In recent years, China's Trialeurodes vaporariorum Westwood and Bemisia tabaci resistance were obvious, and Imidacloprid, Buprofezin, Mobucin etc. are poor effect all.

Buprofezin, english common name buprofezin, chemical name 2-tertiary butyl imino group-3-isopropyl-5-phenyl-1,3,5-thiadiazine-4-ketone.Buprofezin belongs to the Thiadiazinone compound, though do not belong to benzoyl area kind, its desinsection principle is identical with process for preparation of benzoylurea compounds, all is to suppress insect chitin to synthesize.Plant hopper, leafhopper, aleyrodid and shell insects there is good control efficiency.But this medicament is invalid to adult, and speed of action is slow, and owing to use for many years, a lot of insects produce resistance to it, thereby cause control efficiency obviously to descend.

Flonicamid, English common name flonicamid is a kind of picolinamide class insect growth regulator, IGR, is mainly used on cotton, cucurbit, fruit, vegetables, potato, the operatic circle and the drupe.Its mechanism of action uniqueness has good effects on neural system and quick antifeedant activity to insect, does not have cross resistance with existing insecticide.But its pesticide resistance risk of using separately is also higher.

Summary of the invention

The purpose of this invention is to provide a kind of Pesticidal combination.Said composition synergy is remarkable, and the control spectrum is wide, and the antagonism pest controling effect is good, to producing the particularly evident of resistance rice planthopper and trialeurodes vaporariorum; Another purpose of invention provides the application of said composition in control of insect.

For achieving the above object, the inventor is by a large amount of biologicall test screenings, find that Buprofezin and flonicamid are composite with certain proportion, antagonism rice fulgorid and trialeurodes vaporariorum have obvious synergistic effect, to other insects, good field control effect is also arranged as homoptera pests such as trialeurodes vaporariorum, aphid, Bemisia tabaci, leafhopper.

Technical scheme of the present invention is:

Adopt the insecticide of the different mechanisms of action to carry out the biological activity determination of different proportionings, occur three kinds of different situations after the determination of activity of different proportionings usually: summation action, antagonism, synergistic effect.With the synergy proportioning is that effective ingredient is mixed with suitable preparation, is used to prevent and treat the insect on the crops, can effectively reduce the usage amount of medicament, reduces drug cost, the generation of delaying drug resistance, thus minimizing is to the pollution of environment.

The present invention adopts Buprofezin and flonicamid to carry out biological activity test, and the mass ratio of flonicamid and Buprofezin is 10: 1～1: 160, and preferred ratio is 1: 10～1: 40.

The present composition is processed in actual applications and is fit to any dosage formulation that agricultural goes up use, and preferred dosage form is missible oil, microemulsion, aqueous emulsion, water dispersible granules, wetting powder, suspending agent.Described Buprofezin and the flonicamid gross mass content in preparation is 1%-90%, preferred 10%-50%.

Present composition preparation can be used for preventing and treating the resistant insect on the plant, is particularly useful for preventing and treating the insect that existing medicament is produced resistance, is specially adapted to prevent and treat resistance plant hopper and aleyrodid.

Composition pesticide of the present invention compared with prior art produces following beneficial effect: two kinds of active ingredients in (1) composition have synergistic effect, and the outstanding apparition of the synergy of antagonism insect is compared with single agent, has obviously improved control efficiency; (2) can reduce the field dosage, effectively reduce environmental pollution and residue of pesticide, reduce harm beneficial organism; (3) mechanism of action of both active ingredients is different in the composition, and the application of composition helps to delay pest resistance development, prolongs medicament service life.

Embodiment

In order to make purpose of the present invention, technical scheme and technological merit are clearer, below in conjunction with embodiment summary of the invention are described in further detail.Should be appreciated that described specific embodiment only is used to explain the present invention, and be not used in qualification the present invention.All any modifications of being made within the spirit and principles in the present invention, be equal to and replace and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Embodiment one: Buprofezin and flonicamid are to rice fulgorid, the test of trialeurodes vaporariorum indoor virulence

It is tested object that paddy rice brown planthopper and trialeurodes vaporariorum are adopted in test, and concrete grammar is:

(1) test medicine:

The former medicine of 95% Buprofezin (Jiangsu Changlong Chemical Co);

The former medicine of 97.6% flonicamid (Japanese Ishihara Sangyo Kaisha, Ltd.);

Former medicine is mixed with according to a conventional method the test medicine that needs.

(2) subjects:

Paddy rice brown planthopper (Nilaparvata lugens (Stat)): indoor paddy rice seedling raise three age the brown planthopper nymph, responsive examination worm is from Agricultural University Of Nanjing; Resistance examination worm is picked up from the Zhanjiang City, Guangdong Province.

Trialeurodes vaporariorum (Trialeurodes vaporiorum): raise with cucumber seedling in the greenhouse, and tritonymph is for test; Responsive examination worm is picked up from beautiful rule food market, Shenzhen; Resistance examination worm is picked up from the Haikou city.

(3) test method:

Brown planthopper: test method is with reference to " the agricultural industry criteria NY/T1154.11-2008 of the People's Republic of China (PRC) ", adopt rice stem infusion process: extract with root the rice strain at healthy and strong tillering stage to booting initial stage, clean, be cut into the long band root rice stem of 15cm, one group of 3 strain locate to dry in the air not have washmarking to the surface in the cool place.The rice stem was soaked 30 seconds in the good medicament of dilution respectively, after taking-up is dried, encase root with the absorbent cotton that soaks and put into the cultivation cup, draw 3 mid-term in age nymph put into and cultivate cup, 20 every glass, put temperature and be 27 ℃, photoperiod and be in the incubator of 16h:8h (L:D) and raise, the clear water contrast, each concentration repeats 3 times.Check death toll after 5 days.

Trialeurodes vaporariorum: test method is with reference to " the agricultural industry criteria NY/T1154.7-2006 of the People's Republic of China (PRC) ".Test method adopts the potter spray-on process.Pluck the cucumber leaves of band trialeurodes vaporariorum nymph, shear posterior lobe and place the culture dish of being with the agar of preserving moisture back up, every ware a slice is with 30 nymphs for every.Spray every ware spray 2ml, 4 culture dishes of every repetition with the potter spray tower.The clear water contrast, fruit came to an end after 4 days.

(4) statistical analysis

Carry out statistical analysis with the DPS data processing software, calculate the LC of each medicament ₅₀And 95% confidence limit, estimate the insecticidal activity of reagent agent with this to the examination worm.

The co-toxicity coefficient of mixture (CTC value) calculates by following formula:

$\mathrm{ATI}=\frac{S}{M}\×100$

In the formula:

ATI---mixture actual measurement toxicity index;

The LC of S---standard insecticide ₅₀, unit is mg/l;

The LC of M---mixture ₅₀, unit is mg/l.

TTI＝TI _AxP _A+TI _BxP _B

In the formula:

The theoretical toxicity index of TTI---mixture;

TI _A----A medicament toxicity index;

P _AThe percentage composition of-----A medicament in mixture, unit is a percentage;

TI _B----B medicament toxicity index;

P _BThe percentage composition of-----B medicament in mixture, unit is a percentage.

$\mathrm{CTC}=\frac{\mathrm{ATI}}{\mathrm{TTI}}\×100$

In the formula:

The CTC----co-toxicity coefficient;

ATI---mixture actual measurement toxicity index;

The theoretical toxicity index of TTI---mixture.

Composite dose co-toxicity coefficient (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.

(5) interpretation of result

Resistance and responsive brown planthopper virulence test result see the following form 1 and 2:

Table 1 different disposal is to toxicity test result's (sensitive population) of responsive brown planthopper

Handle	??LC 50(mg/??L)	??AT1	??TTI	Co-toxicity coefficient CTC
					Flonicamid	??1.44	??100.00
Buprofezin	??3.58	??40.22
					Flonicamid 10+ Buprofezin 1	??0.89	??161.80	??94.57	??171.10
Flonicamid 1+ Buprofezin 1	??1.56	??92.31	??70.11	??131.66
					Flonicamid 1+ Buprofezin 5	??1.88	??76.60	??50.19	??152.62
Flonicamid 1+ Buprofezin 10	??1.89	??76.19	??45.66	??166.87
					Flonicamid 1+ Buprofezin 20	??1.77	??81.36	??43.07	??188.89
Flonicamid 1+ Buprofezin 40	??2.48	??58.06	??41.68	??139.31
					Flonicamid 1+ Buprofezin 80	??2.28	??63.16	??40.96	??154.19
Flonicamid 1+ Buprofezin 160	??2.81	??51.25	??40.59	??126.24

Toxicity test result's (resistant population) of table 2 different disposal antagonism brown planthopper

Handle	??LC 50??(mg/L)	??AT1	??TTI	Co-toxicity coefficient CTC	Resistance index
						Flonicamid	??1.49	??100.00			??1.03
Buprofezin	??94.34	??1.58			??26.35
						Flonicamid 10+ Buprofezin 1	??0.78	??191.03	??91.05	??209.80
Flonicamid 1+ Buprofezin 1	??1.33	??112.03	??50.79	??220.58
						Flonicamid 1+ Buprofezin 5	??2.92	??51.03	??17.98	??283.76
Flonicamid 1+ Buprofezin 10	??3.99	??37.34	??10.53	??354.75
						Flonicamid 1+ Buprofezin 20	??5.83	??25.56	??6.27	??407.87
Flonicamid 1+ Buprofezin 40	??9.15	??16.28	??3.98	??409.16

Handle	??LC 50??(mg/L)	??AT1	??TTI	Co-toxicity coefficient CTC	Resistance index
						Flonicamid 1+ Buprofezin 80	??23.84	??6.25	??2.79	??223.66
Flonicamid 1+ Buprofezin 160	??33.92	??4.39	??2.19	??200.52

Find out that from table 1,2 flonicamid and buprofezin compound, mass ratio are 10: 1-1:, the CTC of sensitive population and resistant population brown planthopper all greater than 120, is had synergistic effect at 160 o'clock.Wherein antagonism population (parathiazine ketone resistance index is up to 26.35) CTC is higher than sensitive population all greater than 200, shows that flonicamid and the synergy of buprofezin compound antagonism population are particularly evident.In the resistant population test, be 1 with flonicamid and Buprofezin mass ratio again: 10-1: CTC was obviously higher in 40 o'clock, illustrated that synergy is more obvious under this proportioning.

Resistance and responsive trialeurodes vaporariorum virulence test result see the following form 3 and 4:

Table 3 different disposal is to toxicity test result's (sensitive population) of responsive trialeurodes vaporariorum

Handle	??LC 50(mg/??L)	??AT1	??TTI	Co-toxicity coefficient CTC
					Flonicamid	??2.27	??100.00
Buprofezin	??8.94	??25.39
					Flonicamid 10+ Buprofezin 1	??1.88	??120.74	??93.22	??129.53
Flonicamid 1+ Buprofezin 1	??2.54	??89.37	??62.70	??142.55
					Flonicamid 1+ Buprofezin 5	??3.16	??71.84	??37.83	??189.91
Flonicamid 1+ Buprofezin 10	??3.99	??56.89	??32.17	??176.83
					Flonicamid 1+ Buprofezin 20	??4.17	??54.44	??28.94	??188.07
Flonicamid 1+ Buprofezin 40	??5.01	??45.31	??27.21	??166.51
					Flonicamid 1+ Buprofezin 80	??5.89	??38.54	??26.31	??146.47
Flonicamid 1+ Buprofezin 160	??6.71	??33.83	??25.85	??130.85

Toxicity test result's (resistant population) of table 4 different disposal antagonism trialeurodes vaporariorum

Handle	??LC 50??(mg/L)	??AT1	??TTI	Co-toxicity coefficient CTC	Resistance index
						Flonicamid	??2.91	??100.00			??1.28
Buprofezin	??256.95	??1.13			??28.74
						Flonicamid 10+ Buprofezin 1	??1.23	??236.59	??91.01	??259.95
Flonicamid 1+ Buprofezin 1	??2.43	??119.75	??50.57	??236.82
						Flonicamid 1+ Buprofezin 5	??6.47	??44.98	??17.61	??255.40
Flonicamid 1+ Buprofezin 10	??7.89	??36.88	??10.12	??364.43
						Flonicamid 1+ Buprofezin 20	??11.86	??24.54	??5.84	??420.11
Flonicamid 1+ Buprofezin 40	??19.87	??14.65	??3.54	??413.25
						Flonicamid 1+ Buprofezin 80	??44.27	??6.57	??2.35	??279.35
Flonicamid 1+ Buprofezin 160	??67.79	??4.29	??1.75	??245.77

Find out that from table 3,4 flonicamid and buprofezin compound, mass ratio are 10: 1-1:, the CTC of sensitive population and resistant population trialeurodes vaporariorum all greater than 120, is had synergistic effect at 160 o'clock.Wherein antagonism population (parathiazine ketone resistance index is up to 28.74) CTC is higher than sensitive population all greater than 200, shows that flonicamid and the synergy of buprofezin compound antagonism population are particularly evident.In the resistant population test, be 1 with flonicamid and Buprofezin mass ratio again: 10-1: CTC was obviously higher in 40 o'clock, illustrated that synergy is more obvious under this proportioning.

Embodiment three: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 2.63 grams of 95% Buprofezin, former medicine 2.60 grams of 97.6% flonicamid, calcium dodecyl benzene sulfonate 5.25 grams, polyoxyethylene nonylphenol ether 3.55 restrain, supply gross weight to 100 gram with toluene.The method that above component is prepared missible oil routinely drops in the mixing kettle mixes, and stirring forms preparation 5% flonicamid Buprofezin missible oil (mass ratio of flonicamid and Buprofezin is 1: 1).

Should fill a prescription by effective ingredient 40 gram/hectares dilution spraying, be used to prevent and treat rice hoppers (brown planthopper accounts for more than 90%, and parathiazine ketone resistance is 5.2 times, is 153.6 times to the Imidacloprid resistance).Behind the medicine 3 days control efficiency be 93.31%, 20% Buprofezin missible oil and 10% flonicamid missible oil according to using with quadrat method and dosage, 3 days preventive effects are respectively 73.56% and 83.35%, significant difference behind the medicine.Simultaneously composite dose also has certain effect (83.5%) to rice-leaf hopper.

Behind the present embodiment product medicine 21 days to the rice fulgorid control efficiency be 82.31%, 20% Buprofezin missible oil and 10% flonicamid missible oil according to using with quadrat method and dosage, 21 days preventive effects are respectively 26.12% and 71.37%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, thereby reduce environmental pollution, reduce residue of pesticide.

Embodiment four: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 26.32 grams of 95% Buprofezin, former medicine 2.60 grams of 97.6% flonicamid, calcium dodecyl benzene sulfonate 11.5 grams, dimethyl sulfoxide (DMSO) 10.2 grams, propane diols 8.2 gram waters are supplied gross weight to 100 gram.Buprofezin and the former medicine of flonicamid are used earlier dmso solution, ratio in prescription adds propane diols, calcium dodecyl benzene sulfonate mixes, under agitation mixture is added in the entry, obtain 27.5% flonicamid Buprofezin microemulsion (mass ratio of flonicamid and Buprofezin is 1: 10) after being stirred to evenly.

Should fill a prescription by effective ingredient 60 gram/hectares dilution spraying, be used to prevent and treat tea lesser leafhopper.Behind the medicine 3 days control efficiency be 96.58%, 20% Buprofezin microemulsion and 5% flonicamid microemulsion according to using with quadrat method and dosage, 3 days preventive effects are respectively 63.34% and 87.12%, significant difference behind the medicine.Check simultaneously and find that also this compound drug also has certain effect to Bemisia tabaci on the tea tree, preventive effect is 91.25%.

Behind the present embodiment product medicine 21 days to the tea lesser leafhopper control efficiency be 82.24%, 20% Buprofezin microemulsion and 5% flonicamid microemulsion according to using with quadrat method and dosage, 21 days preventive effects are respectively 35.35% and 76.47%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, the expanding prevention spectrum, thus reduce environmental pollution, reduce residue of pesticide.

Embodiment five: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 42.11 grams of 95% Buprofezin, former medicine 1.02 grams of 97.6% flonicamid, alkylaryl polyoxyethylene polyoxypropylene ether 6.5 grams, sodium lignin sulfonate 5.5 grams, xanthans 1.1 grams, water are supplied gross weight to 100 gram.Above component is mixed, after high speed shear, obtain 41% flonicamid buprofezin suspension agent (mass ratio of flonicamid and Buprofezin is 1: 40).

Should fill a prescription by effective ingredient 60 gram/hectares dilution spraying, be used to prevent and treat the plastic tent cucumber trialeurodes vaporariorum.Behind the medicine 3 days control efficiency be 98.55%, 20% buprofezin suspension agent and 5% flonicamid suspending agent according to using with quadrat method and dosage, 3 days preventive effects are respectively 72.13% and 90.27%, significant difference behind the medicine.Check simultaneously and find that also this compound drug also has certain effect to the cucumber aphid, preventive effect is 88.66%.

Behind the present embodiment product medicine 21 days to cucumber trialeurodes vaporariorum control efficiency be 83.88%, 20% buprofezin suspension agent and 5% flonicamid suspending agent according to using with quadrat method and dosage, 21 days preventive effects are respectively 38.17% and 78.86%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, the expanding prevention spectrum, thus reduce environmental pollution, reduce residue of pesticide.

Embodiment six: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 1.05 grams of 95% Buprofezin, former medicine 10.25 grams of 97.6% flonicamid, calcium dodecyl benzene sulfonate 4.4 grams, N-Methyl pyrrolidone 8.5 grams, dimethyl sulfoxide (DMSO) 8.8 restrain, supply gross weight to 100 gram with deionized water.The former medicine of Buprofezin and flonicamid, dimethyl sulfoxide (DMSO), calcium dodecyl benzene sulfonate added with N-Methyl pyrrolidone be in the same place, make dissolving, be stirred into oil phase; Under high-speed stirred, oil phase is mixed with water, make 11% flonicamid Buprofezin aqueous emulsion (mass ratio of flonicamid and Buprofezin is 10: 1).

Should fill a prescription by effective ingredient 20 gram/hectares dilution spraying, be used for control joint melon trialeurodes vaporariorum.Behind the medicine 3 days control efficiency be 94.44%, 20% Buprofezin aqueous emulsion and 5% flonicamid aqueous emulsion according to using with quadrat method and dosage, 3 days preventive effects are respectively 43.77% and 76.27%, significant difference behind the medicine.Check simultaneously and find that also this compound drug also has certain effect to joint melon thrips, preventive effect is 89.89%.

The present embodiment product to joint melon trialeurodes vaporariorum medicine after 21 days control efficiency be 83.54%, 20% Buprofezin aqueous emulsion and 5% flonicamid aqueous emulsion according to using with quadrat method and dosage, 21 days preventive effects are respectively 11.14% and 58.76%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, the expanding prevention spectrum, thus reduce environmental pollution, reduce residue of pesticide.

Embodiment six: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 84.21 grams of 95% Buprofezin, former medicine 0.52 gram of 97.6% flonicamid, sodium lignin sulfonate 2.1 grams, PO-EO block polyether 2.1 grams, carboxymethyl cellulose 1.4 grams, urea 3.6 restrain, supply gross weight to 100 gram with kaolin, above component is mixed, become wetting powder through comminution by gas stream, add a certain amount of water mixing extruder grain again, make 80.5% flonicamid Buprofezin water-dispersible granules (mass ratio of flonicamid and Buprofezin is 1: 160) after the drying screening.

Should fill a prescription by effective ingredient 70 gram/hectares dilution spraying, be used to prevent and treat the plastic tent cucumber Bemisia tabaci.Behind the medicine 3 days control efficiency be 98.22%, 50% Buprofezin water-dispersible granules and 50% flonicamid water-dispersible granules according to using with quadrat method and dosage, 3 days preventive effects are respectively 80.77% and 90.18%, significant difference behind the medicine.Check simultaneously and find that also this compound drug also has certain effect to the cucumber liriomyza bryoniae, preventive effect is 84.73%.

The present embodiment product to cucumber Bemisia tabaci medicine after 21 days control efficiency be 82.64%, 50% Buprofezin water-dispersible granules and 50% flonicamid water-dispersible granules are according to using with quadrat method and dosage, 21 days preventive effects are respectively 43.17% and 76.34%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, the expanding prevention spectrum, thus reduce environmental pollution, reduce residue of pesticide.

Embodiment seven: composite dose of preparation of Buprofezin and flonicamid and field efficacy

Take by weighing former medicine 22.22 grams of 95% Buprofezin, former medicine 0.52 gram of 97.6% flonicamid, lauryl sodium sulfate 2.0 grams, sodium lignin sulfonate 2.5 grams, naphthalene sulfonate 5.2 restrain, complement to 100 grams with kaolin.Above component is mixed, become wetting powder to make 20.5% flonicamid Buprofezin wetting powder (mass ratio of flonicamid and Buprofezin is 1: 40) through comminution by gas stream.

Should fill a prescription by effective ingredient 60 gram/hectares dilution spraying, be used to prevent and treat rice hoppers.Behind the medicine 3 days control efficiency be 98.65%, 50% Buprofezin water-wettable pulvis and 50% flonicamid wetting powder according to using with quadrat method and dosage, 3 days preventive effects are respectively 73.37% and 89.45%, significant difference behind the medicine.

Behind the medicine 21 days control efficiency be 83.64%, 50% Buprofezin wetting powder and 50% flonicamid wetting powder according to using with quadrat method and dosage, 21 days preventive effects are respectively 43.17% and 71.24%, significant difference behind the medicine.Show that composite dose of lasting period rise appreciably, can reduce the medication number of times, the expanding prevention spectrum, thus reduce environmental pollution, reduce residue of pesticide.

Claims (6)

1. composition pesticide, it is characterized in that: contain effective ingredient flonicamid and Buprofezin, the mass ratio between effective ingredient flonicamid and the Buprofezin is 10: 1-1: 160.

2. the described composition pesticide of claim 1, it is characterized in that: the mass ratio between effective ingredient flonicamid and the Buprofezin is 1: 10-1: 40.

3. composition pesticide according to claim 1 and 2 is characterized in that: effective ingredient Buprofezin and the flonicamid quality percentage composition in composition pesticide is 1%～90%.

4. the composition pesticide described in the claim 3 is characterized in that being mixed with one or more formulations in missible oil, microemulsion, aqueous emulsion, water dispersible granules, wetting powder and the suspending agent in agricultural is used.

5. composition pesticide preparation according to claim 4, its application on control crop resistance homoptera pest.

6. according to the application of the described composite preparation of claim 5, it is characterized in that: be used to prevent and treat resistance plant hopper, aleyrodid.