CN101688854A - 用于横跨微构分离通道分配试样和载液的设备 - Google Patents

用于横跨微构分离通道分配试样和载液的设备 Download PDF

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Publication number
CN101688854A
CN101688854A CN200880022752A CN200880022752A CN101688854A CN 101688854 A CN101688854 A CN 101688854A CN 200880022752 A CN200880022752 A CN 200880022752A CN 200880022752 A CN200880022752 A CN 200880022752A CN 101688854 A CN101688854 A CN 101688854A
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China
Prior art keywords
flow distribution
distribution region
little structure
matrix
equipment
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Pending
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CN200880022752A
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English (en)
Chinese (zh)
Inventor
G·德斯梅
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Vrije Universiteit Brussel VUB
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Vrije Universiteit Brussel VUB
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Publication of CN101688854A publication Critical patent/CN101688854A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CN200880022752A 2007-05-23 2008-05-23 用于横跨微构分离通道分配试样和载液的设备 Pending CN101688854A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2007/055008 2007-05-23
EP2007055008 2007-05-23
PCT/EP2008/056369 WO2008142160A1 (en) 2007-05-23 2008-05-23 Device for the distribution of sample and carrier liquid across a micro-fabricated separation channel

Publications (1)

Publication Number Publication Date
CN101688854A true CN101688854A (zh) 2010-03-31

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ID=39745221

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880022752A Pending CN101688854A (zh) 2007-05-23 2008-05-23 用于横跨微构分离通道分配试样和载液的设备

Country Status (5)

Country Link
US (1) US8652420B2 (https=)
JP (1) JP5345136B2 (https=)
CN (1) CN101688854A (https=)
DK (1) DK2150809T3 (https=)
WO (1) WO2008142160A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102933961A (zh) * 2010-06-15 2013-02-13 通用电气健康护理生物科学股份公司 流体分配器单元
CN103008035A (zh) * 2011-09-26 2013-04-03 三星电子株式会社 流体控制装置及包括该流体控制装置的过滤器和生物芯片
CN105102113A (zh) * 2013-02-05 2015-11-25 制药流体股份有限公司 化学反应器装置
CN113365725A (zh) * 2019-01-31 2021-09-07 制药流体股份有限公司 用于化学反应器的过滤器
CN117280207A (zh) * 2020-12-30 2023-12-22 制药流体股份有限公司 柱结构

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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WO2009043057A2 (en) 2007-09-27 2009-04-02 Massachusetts Institute Of Technology Cell rolling separation
EP2213364A1 (en) * 2009-01-30 2010-08-04 Albert-Ludwigs-Universität Freiburg Phase guide patterns for liquid manipulation
US20140138312A1 (en) * 2011-06-09 2014-05-22 Waters Technologies Corporation Reducing Dispersion Due To Vias In Planar Microfluidic Separation Devices
US20140227777A1 (en) * 2011-09-30 2014-08-14 Brigham And Women's Hospital Cell sorting by 3d flow and adhesive rolling
JP6075735B2 (ja) * 2011-09-30 2017-02-08 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 配列された微小構造を用いて流体流れをプログラムするデバイスおよび方法
KR101911436B1 (ko) * 2011-12-13 2018-10-25 삼성전자주식회사 높은 종횡비를 갖는 세포 포획용 필터
EP2618149B1 (en) 2012-01-20 2016-07-27 Ortho-Clinical Diagnostics, Inc. Assay device having uniform flow around corners
US9103468B2 (en) * 2012-07-30 2015-08-11 University Of South Carolina Enhanced flow boiling in microchannels by high frequency microbubble-excited and -modulated oscillations
EP3396355A1 (en) * 2017-04-27 2018-10-31 Pharmafluidics NV Lateral detection of fluid properties
CN112816608B (zh) * 2021-01-22 2025-05-13 中国科学院上海微系统与信息技术研究所 微色谱柱及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427663A (en) * 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
US6156273A (en) * 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
EP1044047A4 (en) * 1997-11-14 2008-04-16 Biotage Inc LIQUID CHROMATOGRAPHY COLUMN
EP0977030B1 (en) * 1998-07-29 2001-03-21 Hewlett-Packard Company Chip for performing an electrophoretic separation of molecules and method using same
EP1154828A1 (en) * 1999-02-25 2001-11-21 Pall Corporation Chromatography devices and flow distributor arrangements used in chromatography devices
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US20050095602A1 (en) * 2003-11-04 2005-05-05 West Jason A. Microfluidic integrated microarrays for biological detection
US20060065528A1 (en) 2004-02-03 2006-03-30 Gabriel Lopez Nanostructured devices for separation and analysis
SE528233C2 (sv) 2005-06-20 2006-09-26 Aamic Ab Metod och medel för att åstadkomma vätsketransport
US8288151B2 (en) * 2005-06-29 2012-10-16 Canon Kabushiki Kaisha Biochemical reaction cassette
JP4878200B2 (ja) * 2005-06-29 2012-02-15 キヤノン株式会社 生化学反応カセット

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102933961A (zh) * 2010-06-15 2013-02-13 通用电气健康护理生物科学股份公司 流体分配器单元
CN102933961B (zh) * 2010-06-15 2015-02-11 通用电气健康护理生物科学股份公司 流体分配器单元
CN103008035A (zh) * 2011-09-26 2013-04-03 三星电子株式会社 流体控制装置及包括该流体控制装置的过滤器和生物芯片
CN103008035B (zh) * 2011-09-26 2018-04-24 三星电子株式会社 流体控制装置及包括该流体控制装置的过滤器和生物芯片
CN105102113A (zh) * 2013-02-05 2015-11-25 制药流体股份有限公司 化学反应器装置
CN105102113B (zh) * 2013-02-05 2018-05-29 制药流体股份有限公司 化学反应器装置
CN113365725A (zh) * 2019-01-31 2021-09-07 制药流体股份有限公司 用于化学反应器的过滤器
CN117280207A (zh) * 2020-12-30 2023-12-22 制药流体股份有限公司 柱结构

Also Published As

Publication number Publication date
US8652420B2 (en) 2014-02-18
JP5345136B2 (ja) 2013-11-20
WO2008142160A1 (en) 2008-11-27
JP2010528276A (ja) 2010-08-19
US20100166611A1 (en) 2010-07-01
DK2150809T3 (da) 2019-08-05

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Application publication date: 20100331