CN101687152B - 单分散微滴的生成 - Google Patents

单分散微滴的生成 Download PDF

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Publication number
CN101687152B
CN101687152B CN2008800232872A CN200880023287A CN101687152B CN 101687152 B CN101687152 B CN 101687152B CN 2008800232872 A CN2008800232872 A CN 2008800232872A CN 200880023287 A CN200880023287 A CN 200880023287A CN 101687152 B CN101687152 B CN 101687152B
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CN
China
Prior art keywords
fluid
cavity
droplet
flow
jet
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Expired - Fee Related
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CN2008800232872A
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English (en)
Chinese (zh)
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CN101687152A (zh
Inventor
A·克拉克
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Eastman Kodak Co
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Eastman Kodak Co
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Publication date
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Publication of CN101687152A publication Critical patent/CN101687152A/zh
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4337—Mixers with a diverging-converging cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Nozzles (AREA)
  • Colloid Chemistry (AREA)
CN2008800232872A 2007-07-03 2008-06-27 单分散微滴的生成 Expired - Fee Related CN101687152B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0712863.0A GB0712863D0 (en) 2007-07-03 2007-07-03 Monodisperse droplet generation
GB0712863.0 2007-07-03
PCT/GB2008/002217 WO2009004314A1 (en) 2007-07-03 2008-06-27 Monodisperse droplet generation

Publications (2)

Publication Number Publication Date
CN101687152A CN101687152A (zh) 2010-03-31
CN101687152B true CN101687152B (zh) 2013-02-06

Family

ID=38421116

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008800232872A Expired - Fee Related CN101687152B (zh) 2007-07-03 2008-06-27 单分散微滴的生成

Country Status (6)

Country Link
US (1) US8302880B2 (enExample)
EP (1) EP2164617B1 (enExample)
JP (1) JP5335784B2 (enExample)
CN (1) CN101687152B (enExample)
GB (1) GB0712863D0 (enExample)
WO (1) WO2009004314A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1861194A2 (en) * 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
EP2286125B1 (en) 2008-05-16 2015-07-08 President and Fellows of Harvard College Valves and other flow control in fluidic systems including microfluidic systems
US8609737B2 (en) * 2008-09-18 2013-12-17 Technische Universiteit Eindhoven Process for preparing monodispersed emulsions
EP2411133B1 (en) 2009-03-25 2013-12-18 Eastman Kodak Company Droplet generator
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
FR2958186A1 (fr) 2010-03-30 2011-10-07 Ecole Polytech Dispositif de formation de gouttes dans un circuit microfluide.
CN101994162A (zh) * 2010-12-10 2011-03-30 江南大学 微流体静电纺丝装置
WO2012162296A2 (en) 2011-05-23 2012-11-29 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
US8936354B2 (en) 2012-03-28 2015-01-20 Eastman Kodak Company Digital drop patterning device and method
US8602535B2 (en) 2012-03-28 2013-12-10 Eastman Kodak Company Digital drop patterning device and method
US8939551B2 (en) 2012-03-28 2015-01-27 Eastman Kodak Company Digital drop patterning device and method
US8936353B2 (en) 2012-03-28 2015-01-20 Eastman Kodak Company Digital drop patterning device and method
GB2502058B (en) * 2012-05-14 2014-08-06 Schlumberger Holdings Determining interfacial tension between first and second immiscible liquids
GB2513310B (en) 2013-04-22 2015-09-16 Schlumberger Holdings Determination of interfacial or surface tension
RU2703858C2 (ru) 2014-12-12 2019-10-22 Дженерал Электрик Компани Устройство и способ кондиционирования потока жирного газа
CN107405633A (zh) * 2015-05-22 2017-11-28 香港科技大学 基于高深宽比诱导生成液滴的液滴发生器
CN105498869B (zh) * 2015-11-27 2017-06-09 中国石油大学(华东) 一种微纳米液滴制备方法
DE102017105194A1 (de) * 2017-03-10 2018-09-13 Little Things Factory Gmbh Fokussiereinrichtung, Tropfengenerator und Verfahren zum Erzeugen einer Vielzahl von Tröpfchen
CN107029640B (zh) * 2017-05-23 2023-04-21 中国科学技术大学 基于液驱流动聚焦射流扰动的微液滴主动制备装置及方法
EP3837377A4 (en) * 2018-08-17 2022-05-18 The Regents of University of California DROPLET FORMATION TRIGGERED BY MONODISPERSE PARTICLES FROM STEADY JETS
CN111841439A (zh) * 2020-08-19 2020-10-30 中国科学技术大学 一种高通量制备均匀单乳液滴的装置及方法
CN112844895B (zh) * 2021-01-03 2021-08-17 清华大学 一种控制液体射流破碎的装置
CN114749219B (zh) * 2022-03-30 2023-06-02 北京航空航天大学 集成压电式均匀液滴发生器

Citations (2)

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US6347883B1 (en) * 1999-01-26 2002-02-19 Kvaerner Pulping Ab Apparatus for adding a first fluid into a second fluid with means to prevent clogging
DE102005048259A1 (de) * 2005-10-07 2007-04-19 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen

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JPS61138529A (ja) * 1984-12-10 1986-06-26 Idemitsu Petrochem Co Ltd サイズ用乳化液の製造方法
GB9406255D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
US5873523A (en) * 1996-02-29 1999-02-23 Yale University Electrospray employing corona-assisted cone-jet mode
AU745904B2 (en) 1997-12-17 2002-04-11 Universidad De Sevilla Device and method for creating spherical particles of uniform size
WO1999030812A1 (en) * 1997-12-17 1999-06-24 Universidad De Sevilla Device and method for aeration of fluids
US6377387B1 (en) 1999-04-06 2002-04-23 E Ink Corporation Methods for producing droplets for use in capsule-based electrophoretic displays
AU2001290879A1 (en) 2000-09-15 2002-03-26 California Institute Of Technology Microfabricated crossflow devices and methods
JP2006507921A (ja) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
WO2004091763A2 (en) * 2003-04-10 2004-10-28 President And Fellows Of Harvard College Formation and control of fluidic species
EP2662136A3 (en) * 2003-08-27 2013-12-25 President and Fellows of Harvard College Method for handling and mixing droplets
WO2005103106A1 (en) 2004-04-23 2005-11-03 Eugenia Kumacheva Method of producing polymeric particles with selected size, shape, morphology and composition
US7759111B2 (en) * 2004-08-27 2010-07-20 The Regents Of The University Of California Cell encapsulation microfluidic device
US20060234051A1 (en) * 2005-01-27 2006-10-19 Zhang Wendy W System and method of obtaining entrained cylindrical fluid flow
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
EP1861194A2 (en) * 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
JP4713397B2 (ja) * 2006-01-18 2011-06-29 株式会社リコー 微小流路構造体及び微小液滴生成システム
JP2008100182A (ja) * 2006-10-20 2008-05-01 Hitachi Plant Technologies Ltd 乳化装置および微粒子製造装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6347883B1 (en) * 1999-01-26 2002-02-19 Kvaerner Pulping Ab Apparatus for adding a first fluid into a second fluid with means to prevent clogging
DE102005048259A1 (de) * 2005-10-07 2007-04-19 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen

Non-Patent Citations (1)

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Title
JP特开昭62-286531A 1987.12.12

Also Published As

Publication number Publication date
EP2164617B1 (en) 2013-03-27
EP2164617A1 (en) 2010-03-24
US8302880B2 (en) 2012-11-06
CN101687152A (zh) 2010-03-31
JP2010531730A (ja) 2010-09-30
JP5335784B2 (ja) 2013-11-06
GB0712863D0 (en) 2007-08-08
US20100170957A1 (en) 2010-07-08
WO2009004314A1 (en) 2009-01-08

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Granted publication date: 20130206

Termination date: 20180627