CN101683412A - Chinese medicine patch for treating children's bronchus asthma and method for producing the same - Google Patents
Chinese medicine patch for treating children's bronchus asthma and method for producing the same Download PDFInfo
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- CN101683412A CN101683412A CN200810151813A CN200810151813A CN101683412A CN 101683412 A CN101683412 A CN 101683412A CN 200810151813 A CN200810151813 A CN 200810151813A CN 200810151813 A CN200810151813 A CN 200810151813A CN 101683412 A CN101683412 A CN 101683412A
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Abstract
The invention provides a Chinese medicine patch for treating children's bronchus asthma and a method for producing the same. The invention contains the following components in proportion by weight: seeds of brassica alba 5-10, almond 3-10, white pepper 3-10; the invention includes the steps of: proportionally mixing raw materials, grinding until particle diameter of each component is 100-200 mu m;using CO2 supercritical extraction, fractionating acquired distillates with a fractionating tower, mixing each component in the formula into nano medicinal pulp according to the formula proportionality through the nano dispersing apparatus, adding accelerating agent for percutaneous absorption and contact adhesive into the circular type low temperation drying coater, and after coating, executingshearing, quality test, packaging and then sending the product into warehouse. The invention uses a scientific method for processing and extracting medicinal materials, which are filled in the framework of the substrate, and the paster substrate has a good compatibility with skin, and is good for medicament molecule to pass; the medicament has the advantages of slow release, smooth and steady administration, small irritation, without toxic and side effects, thereby preventing toxic and side effects for human body brought by oral medication and injection.
Description
Technical field
The present invention relates to a kind of Chinese herbs paste, relate in particular to a kind of Chinese herbs paste and manufacture method for the treatment of bronchial asthma of child.
Background technology
Children's suffers from cough illness, and how due to illness evil visitor blocks lung meridian in the lung network, has influenced the normal operation of lung qi.Impairment of purifying and descending function of the lung, superinverse is then coughed, and lung loses a surname and sends out, and does not declare then and breathes heavily.So the key of treatment infantile asthma is eliminating evil, heresy goes then all disease knowing to remove.General patient adopts medicament to treat usually, mostly is oral drugs or injection, but the equal toxic side effect of oral drugs and injection, can produce through liver first-pass effect and gastrally releases light reaction, so just brings safety problem to the patient.
Summary of the invention
Main purpose of the present invention is to solve the toxic and side effects that oral drugs and injection bring human body, provide a kind of toxic and side effects of having avoided oral administration to use, also without liver first-pass effect and gastral Chinese herbs paste and the manufacture method of releasing light treatment bronchial asthma of child.
The technical solution adopted for the present invention to solve the technical problems is:
Form by following weight proportion component: Semen Sinapis Albae 5-10 part, Semen Armeniacae Amarum 3-10 part, Radix orixae japonicae 3-10 part.To bronchial asthma of child, intractable infantile cough, infantile pneumonia, infantile anorexia etc. are all effective in cure.
The Chinese herbs paste of treatment bronchial asthma of child and the crude drug that manufacture method is following column weight amount proportioning part are made according to following method: Semen Sinapis Albae 5-10 part, Semen Armeniacae Amarum 3-10 part, Radix orixae japonicae 3-10 part.
Respectively Semen Sinapis Albae, Semen Armeniacae Amarum and white pepper powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: 60 parts of polyvinyl alcohol, 120 parts in gelatin, 60 parts of sodium carboxymethyl cellulose, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Dressing is Kaolin, bentonite, zinc oxide, titanium dioxide, adopts more than one at least.Promoter is methyl salicylate, Camphora, Mentholum, adopts more than one at least.Gel matrix is pressure sensitive adhesive, resin glue, rubber, adopts more than one at least.
The present invention is the Chinese herbs paste and the manufacture method of treatment bronchial asthma of child.Extract medical material with scientific method processing, fill in the skeleton that is stated from substrate, paster substrate and skin intermiscibility are good, help drug molecule and pass through, drug release is slow, and administration is steady, zest is little, do not have toxic and side effects, can alleviate disease rapidly, easy to use, medicine is cheap simultaneously, therapeutic effect is good, the toxic and side effects of having avoided oral drugs and injection that human body is brought, also without liver first-pass effect and gastral release light.Can be through the skin iuntercellular with blood circulation to focus, improve bioavailability more than 10 times than like product, therapeutic effect has significance to improve.The present invention compares with the biography its preparation process, aspect the raising and improvement curative effect of bioavailability, with matched group significance statistical significance (P＜0.01) is arranged all.
The specific embodiment
Embodiment 1 (high dose)
Treatment Chinese herbs paste of bronchial asthma of child and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Semen Sinapis Albae 10kg, Semen Armeniacae Amarum 10kg, Radix orixae japonicae 10kg.
Respectively Semen Sinapis Albae, Semen Armeniacae Amarum and white pepper powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Embodiment 2 (low dosage)
Treatment Chinese herbs paste of bronchial asthma of child and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Semen Sinapis Albae 5kg, Semen Armeniacae Amarum 3kg, Radix orixae japonicae 3kg.
Respectively Semen Sinapis Albae, Semen Armeniacae Amarum and white pepper powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Embodiment 3 (median dose)
Treatment Chinese herbs paste of bronchial asthma of child and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Semen Sinapis Albae 7.5kg, Semen Armeniacae Amarum 6.5kg, Radix orixae japonicae 6.5kg.
Respectively Semen Sinapis Albae, Semen Armeniacae Amarum and white pepper powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Claims (3)
1, the Chinese herbs paste of treatment bronchial asthma of child, it is characterized in that being: it is made up of following weight proportion component: Semen Sinapis Albae 5-10 part, Semen Armeniacae Amarum 3-10 part, Radix orixae japonicae 3-10 part.
2, the Chinese herbs paste and the manufacture method of treatment bronchial asthma of child is characterized in that: it is that the crude drug of following column weight amount proportioning part is made according to following method: Semen Sinapis Albae 5-10 part, Semen Armeniacae Amarum 3-10 part, Radix orixae japonicae 3-10 part; Respectively Semen Sinapis Albae, Semen Armeniacae Amarum and white pepper powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20; Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: 60 parts of polyvinyl alcohol, 120 parts in gelatin, 60 parts of sodium carboxymethyl cellulose, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream; Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and cold drying is pasted on the ventilative adhesive plaster, and the lid lining cuts into pieces, quality inspection, finished product packing warehouse-in.
3, the Chinese herbs paste of treatment bronchial asthma of child according to claim 2 and manufacture method is characterized in that dressing is Kaolin, bentonite, zinc oxide, titanium dioxide, adopts more than one at least; Promoter is methyl salicylate, Camphora, Mentholum, adopts more than one at least; Gel matrix is pressure sensitive adhesive, resin glue, rubber, adopts more than one at least.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810151813A CN101683412A (en) | 2008-09-26 | 2008-09-26 | Chinese medicine patch for treating children's bronchus asthma and method for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810151813A CN101683412A (en) | 2008-09-26 | 2008-09-26 | Chinese medicine patch for treating children's bronchus asthma and method for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101683412A true CN101683412A (en) | 2010-03-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810151813A Withdrawn CN101683412A (en) | 2008-09-26 | 2008-09-26 | Chinese medicine patch for treating children's bronchus asthma and method for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101683412A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111514242A (en) * | 2020-06-28 | 2020-08-11 | 西南民族大学 | Medicine and method for treating tracheobronchitis asthma by sala nationality |
-
2008
- 2008-09-26 CN CN200810151813A patent/CN101683412A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111514242A (en) * | 2020-06-28 | 2020-08-11 | 西南民族大学 | Medicine and method for treating tracheobronchitis asthma by sala nationality |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C04 | Withdrawal of patent application after publication (patent law 2001) | ||
| WW01 | Invention patent application withdrawn after publication |
Open date: 20100331 |