CN101683388A - Patch applied on navel for treating enuresis of children and method for producing the same - Google Patents
Patch applied on navel for treating enuresis of children and method for producing the same Download PDFInfo
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- CN101683388A CN101683388A CN200810151812A CN200810151812A CN101683388A CN 101683388 A CN101683388 A CN 101683388A CN 200810151812 A CN200810151812 A CN 200810151812A CN 200810151812 A CN200810151812 A CN 200810151812A CN 101683388 A CN101683388 A CN 101683388A
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- clear paste
- dressing
- navel
- cortex cinnamomi
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Abstract
The invention provides a patch applied on navel for treating enuresis of children and a method for producing the same. The invention contains the following components in proportion by weight: Chinesemagnoliavine 5-10, gallnut 3-10, Cinnamomum Cassia Presl 3-10; the invention includes the steps of: proportionally mixing raw materials, grinding until particle diameter of each component is 100-200 mu m; using CO2 supercritical extraction, fractionating acquired distillates with a fractionating tower, mixing each component in the formula into nano medicinal pulp according to the formula proportionality through the nano dispersing apparatus, adding accelerating agent for percutaneous absorption and contact adhesive into the circular type low temperation drying coater, and after coating, executing shearing, quality test, packaging and then sending the product into warehouse. The invention uses a scientific method for processing and extracting medicinal materials, which are filled in the framework of the substrate, and the paster substrate has a good compatibility with skin, and is good for medicament molecule to pass; the medicament has the advantages of slow release, smooth and steadyadministration, small irritation, without toxic and side effects.
Description
Technical field
The present invention relates to a kind of Chinese herbs paste, relate in particular to a kind of navel patch and manufacture method for the treatment of infantile enuresis.
Background technology
The enuresis is meant more than 3 years old incontinence of urine in children's's sleep, a kind of disease that feel at the rear of waking up.Be because of insufficiency of kidney-YANG, following first deficiency and coldness can not the replenishing vital QI with drugs of warm nature bladder, and hypofunction of the urinary bladder can not restrict due to the water channel.The disease opinion middle enuresis of sleeping, a few days once, or the enuresis every night, very then a night for several times, often with clear urine in large amounts or frequent micturition.In medical the kidney warming consolidate medicine and suit the medicine to the illness, cause curative effect difference because of selecting the medicine difference.
Summary of the invention
Main purpose of the present invention is to provide a kind of navel patch and manufacture method for the treatment of infantile enuresis.
The technical solution adopted for the present invention to solve the technical problems is:
Form by following weight proportion component: Fructus Schisandrae Chinensis 5-10 part, Galla Chinensis 3-10 part, Cortex Cinnamomi 3-10 part.
We have the effect of the kidney warming reducing urination.Select Galla Chinensis for use, Fructus Schisandrae Chinensis is sour and astringent convergence reducing urination; Especially with the Cortex Cinnamomi warming YANG to expel cold, in fragrant priming is gone into, promote functioning of bladder, make its folding degree of having, and the enuresis is from ending.
The navel patch of treatment infantile enuresis and the crude drug that manufacture method is following column weight amount proportioning part are made according to following method: Fructus Schisandrae Chinensis 5-10 part, Galla Chinensis 3-10 part, Cortex Cinnamomi 3-10 part.
Respectively Fructus Schisandrae Chinensis, Galla Chinensis and Cortex Cinnamomi powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: 60 parts of polyvinyl alcohol, 120 parts in gelatin, 60 parts of sodium carboxymethyl cellulose, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Dressing is Kaolin, bentonite, zinc oxide, titanium dioxide, adopts more than one at least.Promoter is methyl salicylate, Camphora, Mentholum, adopts more than one at least.Gel matrix is pressure sensitive adhesive, resin glue, rubber, adopts more than one at least.
The present invention is the navel patch and the manufacture method of treatment infantile enuresis.Extract medical material with scientific method processing, fill in the skeleton that is stated from substrate, paster substrate and skin intermiscibility are good, help drug molecule and pass through, drug release is slow, and administration is steady, zest is little, does not have toxic and side effects, can alleviate disease rapidly, easy to use, simultaneously medicine is cheap, and therapeutic effect is good, can be through the skin iuntercellular with blood circulation to focus, improve bioavailability more than 10 times than like product, therapeutic effect has significance to improve.The present invention compares with the biography its preparation process, aspect the raising and improvement curative effect of bioavailability, with matched group significance statistical significance (P＜0.01) is arranged all.
The specific embodiment
Embodiment 1 (high dose)
Treatment navel patch of infantile enuresis and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Fructus Schisandrae Chinensis 10kg, Galla Chinensis 10kg, Cortex Cinnamomi 10kg.
Respectively Fructus Schisandrae Chinensis, Galla Chinensis and Cortex Cinnamomi powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Embodiment 2 (low dosage)
Treatment navel patch of infantile enuresis and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Fructus Schisandrae Chinensis 5kg, Galla Chinensis 3kg, Cortex Cinnamomi 3kg.
Respectively Fructus Schisandrae Chinensis, Galla Chinensis and Cortex Cinnamomi powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Embodiment 3 (median dose)
Treatment navel patch of infantile enuresis and manufacture method be crude drug by weight ratio every part in 1kg, make according to following method: Fructus Schisandrae Chinensis 7.5kg, Galla Chinensis 6.5kg, Cortex Cinnamomi 6.5kg.
Respectively Fructus Schisandrae Chinensis, Galla Chinensis and Cortex Cinnamomi powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20.
Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: polyvinyl alcohol 60kg, gelatin 120kg, sodium carboxymethyl cellulose 60kg, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream.
Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and the low humidity drying is pasted on the ventilative adhesive plaster, and the lid lining is cut into pieces, quality inspection, packing warehouse-in.
Claims (3)
1, a kind of navel patch for the treatment of infantile enuresis is characterized in that being: it is made up of following weight proportion component: Fructus Schisandrae Chinensis 5-10 part, Galla Chinensis 3-10 part, Cortex Cinnamomi 3-10 part.
2, a kind of navel patch and manufacture method for the treatment of infantile enuresis is characterized in that: it is that the crude drug of following column weight amount proportioning part is made according to following method: Fructus Schisandrae Chinensis 5-10 part, Galla Chinensis 3-10 part, Cortex Cinnamomi 3-10 part; Respectively Fructus Schisandrae Chinensis, Galla Chinensis and Cortex Cinnamomi powder are broken into coarse powder, decoct with water 1-3 time respectively then, each 1-3 hour, collecting decoction filtered, and surveying relative density when filtrate is concentrated into 80 ℃ is the clear paste of 1.00-1.20; Merge above-mentioned clear paste, surveying relative density when continuing to be concentrated into 80 ℃ is the clear paste of 1.10-1.30, adds dressing then; Dressing is: 60 parts of polyvinyl alcohol, 120 parts in gelatin, 60 parts of sodium carboxymethyl cellulose, 480 parts of glycerol and an amount of distilled water, add mix homogeneously, and be prepared into cloth cream; Cloth cream is coated on cloth or non-woven fabrics or the polyethylene sheets, and cold drying is pasted on the ventilative adhesive plaster, and the lid lining cuts into pieces, quality inspection, finished product packing warehouse-in.
3, the navel patch of treatment infantile enuresis according to claim 2 and manufacture method is characterized in that dressing is Kaolin, bentonite, zinc oxide, titanium dioxide, adopts more than one at least; Promoter is methyl salicylate, Camphora, Mentholum, adopts more than one at least; Gel matrix is pressure sensitive adhesive, resin glue, rubber, adopts more than one at least.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810151812A CN101683388A (en) | 2008-09-26 | 2008-09-26 | Patch applied on navel for treating enuresis of children and method for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810151812A CN101683388A (en) | 2008-09-26 | 2008-09-26 | Patch applied on navel for treating enuresis of children and method for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101683388A true CN101683388A (en) | 2010-03-31 |
Family
ID=42046918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810151812A Withdrawn CN101683388A (en) | 2008-09-26 | 2008-09-26 | Patch applied on navel for treating enuresis of children and method for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101683388A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194638A (en) * | 2015-11-10 | 2015-12-30 | 冷军 | Hilum therapy medicine for treating urination and defecation disorders |
| CN109939085A (en) * | 2019-02-20 | 2019-06-28 | 杭州美迪生物医药技术开发有限公司 | A kind of infantile enuresis physical therapy plaster and preparation method thereof |
-
2008
- 2008-09-26 CN CN200810151812A patent/CN101683388A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194638A (en) * | 2015-11-10 | 2015-12-30 | 冷军 | Hilum therapy medicine for treating urination and defecation disorders |
| CN109939085A (en) * | 2019-02-20 | 2019-06-28 | 杭州美迪生物医药技术开发有限公司 | A kind of infantile enuresis physical therapy plaster and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C04 | Withdrawal of patent application after publication (patent law 2001) | ||
| WW01 | Invention patent application withdrawn after publication |
Open date: 20100331 |