CN101680898A - Timp-1作为结肠直肠癌标志的用途 - Google Patents

Timp-1作为结肠直肠癌标志的用途 Download PDF

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Publication number
CN101680898A
CN101680898A CN200880015574A CN200880015574A CN101680898A CN 101680898 A CN101680898 A CN 101680898A CN 200880015574 A CN200880015574 A CN 200880015574A CN 200880015574 A CN200880015574 A CN 200880015574A CN 101680898 A CN101680898 A CN 101680898A
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CN
China
Prior art keywords
timp
complex
colorectal cancer
sample
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880015574A
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English (en)
Chinese (zh)
Inventor
W·罗林杰
H·安德烈斯
U·加查雷克
A·盖斯坦杰
P·海斯
J·卡尔
F·克劳斯
N·威尔德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN101680898A publication Critical patent/CN101680898A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200880015574A 2007-05-10 2008-05-07 Timp-1作为结肠直肠癌标志的用途 Pending CN101680898A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07009396 2007-05-10
EP07009396.8 2007-05-10
PCT/EP2008/003642 WO2008138522A1 (en) 2007-05-10 2008-05-07 Use of timp-1 as a marker for colorectal cancer

Publications (1)

Publication Number Publication Date
CN101680898A true CN101680898A (zh) 2010-03-24

Family

ID=38521224

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880015574A Pending CN101680898A (zh) 2007-05-10 2008-05-07 Timp-1作为结肠直肠癌标志的用途

Country Status (6)

Country Link
US (1) US20100159479A1 (enExample)
EP (1) EP2145190A1 (enExample)
JP (1) JP2010526995A (enExample)
CN (1) CN101680898A (enExample)
CA (1) CA2684024A1 (enExample)
WO (1) WO2008138522A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102803967A (zh) * 2009-04-07 2012-11-28 基督教高等教育科学研究及病人护理协会 用于结直肠腺癌的诊断的基于蛋白质的方法和组合物
CN103140760A (zh) * 2010-07-14 2013-06-05 联邦科学与工业研究组织 结肠直肠癌的诊断
CN104178562A (zh) * 2013-05-21 2014-12-03 生物梅里埃股份公司 一种大肠癌预后试剂盒
CN105891372A (zh) * 2016-06-12 2016-08-24 上海阿趣生物科技有限公司 原发性肝癌伴胆管癌栓生物标志物及其用途
CN113122544A (zh) * 2021-04-25 2021-07-16 杭州广科安德生物科技有限公司 一种特异性结合timp1蛋白的核酸适配体及其应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE521894T1 (de) * 2007-11-20 2011-09-15 Hoffmann La Roche Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324636A (en) * 1991-07-24 1994-06-28 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Radiorespirometer and method of use
US5455160A (en) * 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
US6037138A (en) * 1996-04-26 2000-03-14 The Children's Medical Center Corp. Enzyme screen for breast cancer
US7374886B2 (en) * 1999-04-09 2008-05-20 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
DE60021068T2 (de) * 1999-04-09 2006-05-18 Rigshospitalet Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker
AU1169702A (en) * 2000-10-13 2002-04-22 Childrens Medical Center Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2005095978A1 (en) * 2004-03-30 2005-10-13 Roche Diagnostics Gmbh Pyrroline-5-carboxylate reductase as a marker for colorectal concer
FR2919063B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
FR2919065B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102803967A (zh) * 2009-04-07 2012-11-28 基督教高等教育科学研究及病人护理协会 用于结直肠腺癌的诊断的基于蛋白质的方法和组合物
CN103140760A (zh) * 2010-07-14 2013-06-05 联邦科学与工业研究组织 结肠直肠癌的诊断
CN103140760B (zh) * 2010-07-14 2016-01-27 联邦科学与工业研究组织 结肠直肠癌的诊断
CN104178562A (zh) * 2013-05-21 2014-12-03 生物梅里埃股份公司 一种大肠癌预后试剂盒
CN105891372A (zh) * 2016-06-12 2016-08-24 上海阿趣生物科技有限公司 原发性肝癌伴胆管癌栓生物标志物及其用途
CN113122544A (zh) * 2021-04-25 2021-07-16 杭州广科安德生物科技有限公司 一种特异性结合timp1蛋白的核酸适配体及其应用

Also Published As

Publication number Publication date
US20100159479A1 (en) 2010-06-24
JP2010526995A (ja) 2010-08-05
CA2684024A1 (en) 2008-11-20
WO2008138522A1 (en) 2008-11-20
EP2145190A1 (en) 2010-01-20

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