JP2010526995A - 結腸直腸癌のマーカーとしてのｔｉｍｐ−１の使用 - Google Patents

結腸直腸癌のマーカーとしてのｔｉｍｐ−１の使用 Download PDF

Info

Publication number
JP2010526995A
JP2010526995A JP2010506846A JP2010506846A JP2010526995A JP 2010526995 A JP2010526995 A JP 2010526995A JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010526995 A JP2010526995 A JP 2010526995A
Authority
JP
Japan
Prior art keywords
timp
stool
colorectal cancer
marker
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010506846A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010526995A5 (enExample
Inventor
ロリンガー，ウォルフガング
アンドレス，ヘルベルト
ガルツァレック，ウルズラ
ガイスタンガー，アンドレア
ハイス，ペーター
カール，ヨハン
クラウゼ，フリーデマン
ヴィルト，ノルベルト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2010526995A publication Critical patent/JP2010526995A/ja
Publication of JP2010526995A5 publication Critical patent/JP2010526995A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • G01N33/57535—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2010506846A 2007-05-10 2008-05-07 結腸直腸癌のマーカーとしてのｔｉｍｐ−１の使用 Withdrawn JP2010526995A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07009396 2007-05-10
PCT/EP2008/003642 WO2008138522A1 (en) 2007-05-10 2008-05-07 Use of timp-1 as a marker for colorectal cancer

Publications (2)

Publication Number Publication Date
JP2010526995A true JP2010526995A (ja) 2010-08-05
JP2010526995A5 JP2010526995A5 (enExample) 2011-02-17

Family

ID=38521224

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010506846A Withdrawn JP2010526995A (ja) 2007-05-10 2008-05-07 結腸直腸癌のマーカーとしてのｔｉｍｐ−１の使用

Country Status (6)

Country Link
US (1) US20100159479A1 (enExample)
EP (1) EP2145190A1 (enExample)
JP (1) JP2010526995A (enExample)
CN (1) CN101680898A (enExample)
CA (1) CA2684024A1 (enExample)
WO (1) WO2008138522A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5227418B2 (ja) * 2007-11-20 2013-07-03 エフ．ホフマン−ラ ロシュ アーゲー マーカー組み合わせカルプロテクチンおよびヘモグロビン／ハプトグロビン複合体の使用による便試料からの結腸直腸癌の評価方法
EP2239577A1 (en) * 2009-04-07 2010-10-13 Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma
CN103140760B (zh) * 2010-07-14 2016-01-27 联邦科学与工业研究组织 结肠直肠癌的诊断
US10072300B2 (en) * 2013-05-21 2018-09-11 Biomerieux Kit for the prognosis of colorectal cancer
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
CN105891372B (zh) * 2016-06-12 2018-11-02 上海阿趣生物科技有限公司 原发性肝癌伴胆管癌栓生物标志物及其用途
CN113122544A (zh) * 2021-04-25 2021-07-16 杭州广科安德生物科技有限公司 一种特异性结合timp1蛋白的核酸适配体及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324636A (en) * 1991-07-24 1994-06-28 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Radiorespirometer and method of use
US5455160A (en) * 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
AU2681997A (en) * 1996-04-26 1997-11-19 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2000062070A2 (en) * 1999-04-09 2000-10-19 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (timp-1) as a cancer marker
US7374886B2 (en) * 1999-04-09 2008-05-20 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
AU1169702A (en) * 2000-10-13 2002-04-22 Childrens Medical Center Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2005095978A1 (en) * 2004-03-30 2005-10-13 Roche Diagnostics Gmbh Pyrroline-5-carboxylate reductase as a marker for colorectal concer
FR2919065B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
FR2919063B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.

Also Published As

Publication number Publication date
US20100159479A1 (en) 2010-06-24
CN101680898A (zh) 2010-03-24
EP2145190A1 (en) 2010-01-20
CA2684024A1 (en) 2008-11-20
WO2008138522A1 (en) 2008-11-20

Similar Documents

Publication Publication Date Title
EP2021794B1 (en) Use of protein s100a 12 as a marker for colorectal cancer
ES2527649T3 (es) Panel de marcadores para el cáncer colorrectal
CA2701341C (en) Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex
US20080064047A1 (en) Methods for diagnosis and prognosis of epithelial cancers
CA2629071A1 (en) Method of assessing colorectal cancer by measuring hemoglobin and m2-pk in a stool sample
US20100159479A1 (en) Timp-1 as a marker for colorectal cancer
JP4847873B2 (ja) 上皮起源の癌を診断および予後診断するための方法
CN108369233B (zh) 基于标志物人附睾蛋白4 (he4)检测肺腺癌的复发的方法及相关用途
US20220390453A1 (en) Ovarian cancer biomarker and methods of using same
HK1142130A (en) Use of timp-1 as a marker for colorectal cancer
CA3163199A1 (en) Ovarian cancer biomarker and methods of using same
HK1149956B (en) Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101221

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20101221

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20120118