CN101669663B - Mulberry active juice beverage for sobering up and protecting liver and preparation method thereof - Google Patents
Mulberry active juice beverage for sobering up and protecting liver and preparation method thereof Download PDFInfo
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- CN101669663B CN101669663B CN200910090901A CN200910090901A CN101669663B CN 101669663 B CN101669663 B CN 101669663B CN 200910090901 A CN200910090901 A CN 200910090901A CN 200910090901 A CN200910090901 A CN 200910090901A CN 101669663 B CN101669663 B CN 101669663B
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 33
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- 208000007848 Alcoholism Diseases 0.000 description 7
- 201000007930 alcohol dependence Diseases 0.000 description 7
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- 238000002474 experimental method Methods 0.000 description 6
- 229930013930 alkaloid Natural products 0.000 description 5
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- 125000001931 aliphatic group Chemical group 0.000 description 4
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- 150000002632 lipids Chemical class 0.000 description 2
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- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000006587 Glutathione peroxidase Human genes 0.000 description 1
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- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- 240000000233 Melia azedarach Species 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
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- 208000010706 fatty liver disease Diseases 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
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- 239000008103 glucose Substances 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
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- 239000002245 particle Substances 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
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- 231100000331 toxic Toxicity 0.000 description 1
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- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 229930182493 triterpene saponin Natural products 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a mulberry active juice beverage for sobering up and protecting the liver and a preparation method thereof. The mulberry active juice beverage mainly comprises the following raw materials by mass percent: 128% of mulberry concentrate juice, 15% of mulberry, 1% of mulberry leaf and 512% of purified water. The juice beverage not only can prevent in advance or fast relieve various drunk symptoms such as dizziness and headache, nausea and vomiting, retch, inappetence and the like, but also can obviously palliate the damage to the liver by alcohol, thus effectively protecting liver function. Furthermore, the juice beverage belongs to pure natural organic juice beverage which contains no preservatives and stabilizing agents, tastes sour and sweet, and drinks conveniently, thus being easily accepted by consumers.
Description
Technical field
The present invention designs a kind of health drink, relates in particular to a kind of health drink with relieving alcoholism and protecting liver effect, the invention still further relates to this preparation method of health-care beverage, belongs to field of health care products.
Background technology
A statistics of mental hygiene research institute of Peking University shows, China's popularity of wine ascendant trend linearly always has 114100 people to die from alcoholism every year in recent years, accounts for 1.3% of general mortality rate; 2737000 people of disabling account for 3.0% of total disability rate.The most crucial chemical substance of wine is an alcohol, drunk actual be alcoholism.Alcohol gets in the human body more than 90% through liver metabolism; The alcoholic can produce symptoms such as dizzy headache, gastric disorder causing nausea, n and V, disequilibrium, and the metabolite of severe patient alcohol and its caused liver cell metabolic disorder meeting cause serious diseases such as fatty liver, alcoholic liver, cirrhosis.
The disintoxicating product that has had on the market has a variety of, and existing disintoxicating product takes effect slowly, drunk principle is not analyzed, and protection also strengthens liver function, fundamentally plays the effect of relieving the effect of alcohol.
Mulberry tree has had the plantation in more than 4000 year historical in China, and mulberry leaf, ramulus mori, mulberry skin etc. all can be used as the drug therapy disease.Along with high-tech development and utilization, the research degree of depth of mulberry tree significantly increases after the nineties, and the development and use direction is expanded gradually.Existing discovering contained flavones, alkaloid, aliphatic acid, triterpene saponin and butanols isoreactivity material among mulberry leaf, mulberry branch and the Sang Pi, and contains carbohydrate and a large amount of crude protein materials such as multienzyme tartaric acid, fructose, sucrose, glucose.These materials have certain function for protection liver, prevention alcoholism and accelerated decomposition alcohol.
Summary of the invention
The technical problem that the present invention will solve is to break through existing material and the technology of relieving the effect of alcohol; Principle from the alcohol absorption; The wine that drink is gone into decomposes rapidly earlier under one's belt with in the blood, reduces ethanol as far as possible and gets into the blood circulation system and go into liver, to alleviate burden of liver; Impel ethanol in stomach, to obtain biodegradation earlier, thereby reach the effect of relieving alcoholism and protecting liver.A kind of new relieving alcoholism and protecting liver active juice beverage is provided simultaneously, is from mulberry fruit and mulberry leaf, to extract flavones, alkaloid, aliphatic acid and butanols isoreactivity material, formulated by specific proportions.
The technical problem that the present invention at first will solve realizes through following scheme.Mulberry juice carbonated beverage is characterized in that it is made up of following component by mass percentage:
1. mulberry concentrated juice 128
2. mulberry fruit 15
3. mulberry leaf 1
4. pure water 512
The rising of serum glutaminic acid transaminase improves glutathione Peroxidase activity in serum and the liver due to reduction such as 1 flavones, alkaloid and the aliphatic acid alcohol, suppresses the generation of peroxidating product MDA.Biological flavone can be removed the free radical that alcohol produces at hepatic tissue.The body injury that alcohol is caused has protective effect.Alkaloid can resist the liver excretory function that causes of drinking and descend.Also can reduce high triglyceride in the blood that alcohol causes, reduce the gastric ulcer index.The triterpenoid saponin constituents also has the effect that the alcohol stomach and intestine absorb that suppresses in addition.
2 flavones, alkaloid and aliphatic acid etc. directly act on hepatic metabolism enzyme system, and the elimination speed of acceleration of alcohol and metabolite thereof alleviates its infringement to tissue and cell.Strengthen alcohol dehydrogenase, glutathione S-transferase activity, obviously reduce steatosis, sheet-like particle sex change and point-like meronecrosis that liver cell appears in alcohol.
3 low-density lipoproteins (LDL) oxidative deformation is one of key factor of incidence of atherosclerosis; The butanol extract of mulberry active thing has LDL oxidative deformation inhibitory action, and the hyperlipidemia serum lipids is increased mulberry active thing extract and atherosclerotic has inhibitory action; Can reduce blood fat, suppress the generation of harmful peroxide, thereby rising of hyperlipidemia serum lipids and atherosclerotic are had inhibitory action.
Mulberry active juice beverage of the present invention is prepared into beverage according to the conventional method of food processing field.Its preparation method comprises following step preface:
(1) cleans, the mulberry fruit cleaning and removing impurities;
(2) squeeze the juice, mulberry fruit through juice extractor, is collected fruit juice, filter out impurity, obtain raw muberry juice;
(3) Brix60 ° of inspissated juice adopts the low pressure concentration method, and it is 60% inspissated juice that raw muberry juice is condensed into pol
(4) mulberry concentrated juice, mulberry fruit was soaked 6 hours with edible alcohol fully, and taking out leachate is first not good liquor; Mulberries were soaked 9 hours with edible alcohol once more; Taking out leachate is second not good liquor, and second not good liquor is put into baking oven liquid adding for the first time after 15 minutes, obtains the mulberry fruit concentrate;
(5) mulberry leaf inspissated juice is put into deionized water with new fresh mulberry leaf and is heated 2min, the 1200r/min 5min that pulls an oar, and 150 orders filter, and 50 ℃ of vacuum are concentrated into dried.Get 10g and seal with filter paper, put into Soxhlet extractor, adding the 50ml absolute ethyl alcohol respectively is solvent, and the water-bath heating a little more than solvent boiling point temperature backflow 4h, is reclaimed solvent, obtains the mulberry leaf concentrate.
(6) host preparation after two kinds of concentrates mixing, is injected the concentrate of Brix60 ° of cloudy mulberry juice, fully mixes;
(7) strict control host pH value and pol slowly add entry in host, and the control pH value is 3.9-4.1, use citric acid to regulate in case of necessity.Pol is controlled to be 12 °.Do not stop to stir, keep in Dark Place.
(8) sterilization, 102-115 ℃, 45s high temperature sterilization are in time carried out in sterilization after solution prepares;
(9) can is cooled off in can after the sterilization.
The present invention really drinks and not only can prevent and the rapid drunk symptom (dizzy headache, gastric disorder causing nausea, n and V, disequilibrium etc.) of alleviating, and can also improve liver function, fundamentally solves the harm of alcohol to human body.In addition, the invention belongs to pure green organic food, do not contain any anticorrisive agent and stabilizing agent, special taste, without any side effects, accepted by the consumer easily.
The specific embodiment
Making has the mulberry active juice beverage of Soboring-up liver-protecting effect
1. prescription is equipped with (unit: kilogram) by following component
Mulberry concentrated juice 195
Mulberry fruit 23
Mulberry leaf 2
Pure water 780
2. preparation method comprises following operation:
(1) cleans, the mulberry fruit cleaning and removing impurities;
(2) squeeze the juice, mulberry fruit through juice extractor, is collected fruit juice, filter out impurity, obtain raw muberry juice;
(3) Brix60 ° concentrates, and adopts the vacuum concentration method, and it is 60% inspissated juice that raw muberry juice is condensed into pol, but long term storage is subsequent use;
(4) mulberry tree concentrate, mulberry fruit was soaked 6 hours with edible alcohol fully, and taking out leachate is first not good liquor; Mulberry fruit was soaked 9 hours with edible alcohol once more; Taking out leachate is second not good liquor, and second not good liquor is put into baking oven liquid adding for the first time after 15 minutes, obtains the mulberry fruit concentrate;
(5) mulberry leaf concentrate is put into deionized water with new fresh mulberry leaf and is heated 2min, and with the 1200r/min 5min that pulls an oar, the back is put into 50 ℃ of vacuum again and is concentrated into dried with the filtration of 150 orders.Get 10g and seal with filter paper, put into Soxhlet extractor, adding the 50ml absolute ethyl alcohol respectively is solvent, and the water-bath heating a little more than solvent boiling point temperature backflow 4h, is reclaimed solvent, obtains the mulberry leaf concentrate;
(6) host preparation after two kinds of concentrates mixing, is injected the concentrate of Brix60 ° of cloudy mulberry juice, fully mixes;
(7) strict control pH value and pol slowly add entry in host, and the control pH value is 3.9-4.1, use a small amount of citric acid to regulate in case of necessity.Pol is controlled to be 12 °.Do not stop to stir, keep in Dark Place;
(8) sterilization, 102-115 ℃, 45s high temperature sterilization are in time carried out in sterilization after solution prepares;
(9) can is cooled off in can after the sterilization.
Experiment
The experiment of relieving the effect of alcohol that the gloomy treasured of a specified duration of state is done at institute of Materia Medica,Chinese Academy of Medical Sciences, and toxic and side effect experiment.
Given the test agent: this programme is implemented prepared mulberry active juice beverage;
Mouse is chosen in anti-liquor-saturated experiment, random packet, and each is organized mouse and feeds with standard feed, freely drinks water.Test last group of mouse and only give water, another group gives mulberry active juice beverage, after 1 hour, gives every group of mouse equivalent liquor.Observe mouse from irritating wine to drunk situation, observe mice drunk and death toll.
Mouse is chosen in the experiment of relieving the effect of alcohol, random packet, and each is organized mouse and feeds with standard feed, freely drinks water.When beginning experiment gives every group of mouse equivalent liquor, after 30 minutes, every group of mouse give respectively low (0.4ml), in (0.6ml), high dose (0.8ml) mulberry active juice beverage, control group mice is irritated stomach and is given water 0.6ml, observes mouse and sobers up and death toll.
The conclusion mulberry active juice beverage can reduce drunk rate, the death rate of mouse, and prolongs the latent time of sleeping, and has tangible anti-drunk function.After drunk mouse gives the gloomy treasured of a specified duration of state, the mouse quantity showed increased of reviving in 10 hours, the death rate obviously descends, and antialcoholism action is arranged.
Experimental result shows that mulberry active juice beverage of the present invention has definite effects such as relieving alcoholism and protecting liver.
Claims (1)
1. method for preparing mulberry beverage,
Said mulberry beverage is equipped with by following component
Said method comprises the steps:
(1) with the mulberry fruit cleaning and removing impurities;
(2) mulberry fruit after will cleaning is collected fruit juice through juice extractor, filters out impurity, obtains raw muberry juice;
(3) adopt the vacuum concentration method, it is Brix60 ° mulberry concentrated juice that raw muberry juice is condensed into pol, subsequent use;
(4) mulberry fruit was soaked 6 hours with edible alcohol fully; Taking out leachate is first not good liquor, and mulberries were soaked 9 hours with edible alcohol once more, and taking out leachate is second not good liquor; Second not good liquor is put into baking oven after 15 minutes first not good liquor is added, obtain the mulberry fruit concentrate;
(5) new fresh mulberry leaf is put into deionized water and heat 2min, the 1200r/min 5min that pulls an oar, filter with 150 orders the back; It is dried to place 50 ℃ of vacuum to be concentrated into again, and the product 10g that obtains seals with filter paper, puts into Soxhlet extractor; Add solvent 50ml absolute ethyl alcohol respectively, water-bath heating is a little more than solvent boiling point temperature backflow 4h; Reclaim solvent, obtain the mulberry leaf concentrate;
(6) mulberry fruit concentrate and mulberry leaf concentrate are mixed, it is Brix60 ° mulberry concentrated juice that the mixed liquor that obtains is injected pol, fully mixes, and obtains mixed solution;
(7) in said mixed solution, slowly add entry, do not stop to stir, obtain product and keep in Dark Place, wherein the pol of product is 12 °, and pH value is 3.9-4.1;
(8) with the timely sterilization 45s under 102-115 ℃ temperature of the product that obtains;
(9) cool off the product after the sterilization canned.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910090901A CN101669663B (en) | 2009-08-13 | 2009-08-13 | Mulberry active juice beverage for sobering up and protecting liver and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910090901A CN101669663B (en) | 2009-08-13 | 2009-08-13 | Mulberry active juice beverage for sobering up and protecting liver and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101669663A CN101669663A (en) | 2010-03-17 |
| CN101669663B true CN101669663B (en) | 2012-08-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200910090901A Expired - Fee Related CN101669663B (en) | 2009-08-13 | 2009-08-13 | Mulberry active juice beverage for sobering up and protecting liver and preparation method thereof |
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| CN (1) | CN101669663B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102178222B (en) * | 2011-03-30 | 2012-12-12 | 北京同仁堂国际药业有限公司 | Edible composition as well as preparation method and application thereof |
| CN106560080A (en) * | 2015-09-30 | 2017-04-12 | 刘小会 | Health food for preventing and treating hepatic fibrosis of hepatitis B patients, and preparation process thereof |
| CN105410569B (en) * | 2015-12-08 | 2018-07-24 | 广东省农业科学院蚕业与农产品加工研究所 | A kind of preparation method to mulberry beverage of the alcoholic liver injury with protective effect |
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2009
- 2009-08-13 CN CN200910090901A patent/CN101669663B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN101669663A (en) | 2010-03-17 |
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