CN101664480A - Chinese herbal medicine medicament for treating hyperosteogeny - Google Patents
Chinese herbal medicine medicament for treating hyperosteogeny Download PDFInfo
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Abstract
The invention relates to a Chinese herbal medicine medicament for treating hyperosteogeny, which is a plaster or a tincture prepared from 13 Chinese herbal medicine materials of Chinese dodder, spatholobus stem, honeysuckle stem, rhizoma drynariae, psoralea corylifolia, eucommia bark, radix cyathulae, medlar, glossy privet fruit, herba ecliptae, Wu Chia Pee, radix puerariae and pubescent angelicaroot. The medicament is suitable for treating various bone diseases, such as hyperosteogeny, rheumatism, rheumatoid arthritis, femoral head necrosis, cervical spondylosis, scapulohumeral periarthritis, lumbar vertebrae disk protrusion, sciatica, osteoporosis and no bone healing after fracture, has obvious curative effect, high cure rate, low relapse rate, no side effect, convenient taking and lowcost and treats the superficiality and the origin of the diseases.
Description
Technical field
The invention belongs to field of Chinese herbal medicine technology, particularly a kind of herbal mediciment for the treatment of bone matrix hyperplasia.
Background technology
Bone matrix hyperplasia has another name called hyperplastic osteoarthritis, degenerative osteoarthritis, hypertrophiarthritis, osteoarthritis, and a yellow tame team of four horses " surgery " is referred to as osseous arthritis, is general reference degeneration joint disease, belongs to the category of the traditional Chinese medical science " arthromyodynia ", " rheumatism involving the bone ".Support because congenital defect or the day after tomorrow lose, cause Liver and kidney two void, be difficult to full muscles and bones, the withered then marrow of bone subtracts, sclerotin thereby loose, and long-term over loading is born a heavy burden, skeleton and then distortion, muscles and bones must not be moistened and be moistened fosterly, arthralgia then occurs, and is movable unfavorable.With the passing of time deficiency of the liver and kindey must involve deficiency of qi and blood, so bone matrix hyperplasia is a basis with deficiency of the liver and kindey, essence and blood loss, experiences wind, cold, wet, hot, and qi stagnation blood stasis is mark.Bone matrix hyperplasia can make any joint involvement, and is the most common with cervical vertebra, lumbar vertebra and knee joint especially, is the important cause of disease that causes neck shoulder, lumbago and skelalgia.Bone matrix hyperplasia is comparatively common, the multiple and chronic diseases that are difficult to cure of a kind of person in middle and old age, does not find to stop the medicine of lesion growth so far as yet, and the also incompetent medicine that reverses degeneration comes out.At present, the medicine for the treatment of bone matrix hyperplasia clinically is many and random, can only symptomatic treatment, having many drawbacks, as NSAID (non-steroidal anti-inflammatory drug) ibuprofen, piroxicam etc., mainly is analgesia, antiinflammatory and analgesic, though energy respite pain, drug withdrawal is promptly recurred, and side effect is bigger, and nausea,vomiting,diarrhea, stomachache, digestive tract ulcer and hemorrhage are often arranged; Headache, dizzy, tinnitus, edema, depression, sleepy, insomnia, blurred vision, erythra etc.; Idol has abnormal liver function, renal function injury, granulocyte and thrombocytopenia etc.Though glucocorticoid has powerful antiinflammatory action, and the rapid relief of symptoms of energy, it also can cause hypertension, hyperlipidemia, diabetes, osteoporosis and rebound phenomenon and withdrawal symptom except that above-mentioned side effect is arranged.In nearly period, middle medical circles release many comprehensive improvement prescriptions successively, and how not obvious therapeutic effect is also.
Summary of the invention
The object of the present invention is to provide and a kind ofly can treat various osteopathia effectively, and can stop or delay the generation of bone matrix hyperplasia, alleviate or eliminate the herbal mediciment of treatment bone matrix hyperplasia of the various incompatibility symptoms of bone matrix hyperplasia.
The technical scheme of being taked is for achieving the above object: this Chinese herbal medicine is formulated by the Chinese medicinal herbs of following weight portion: 30～90 parts of Semen Cuscutae, 30～90 parts of Caulis Spatholobis, 30～90 parts of Caulis Loniceraes, 20～60 parts of Rhizoma Drynariae, 20～60 parts of Fructus Psoraleaes, 20～60 parts of the Cortexs Eucommiae, 20～60 parts of Radix Cyathulaes, 15～35 parts of Fructus Lycii, 15～35 parts of Fructus Ligustri Lucidi, 15～35 parts of Herba Ecliptaes, 10～30 parts of Cortex Acanthopanciss, 10～30 parts of Radix Puerariaes, 10～30 parts of Radix Angelicae Pubescentiss.
Among the present invention, Semen Cuscutae acrid in the mouth, sweet, flat is gone into the Liver and kidney warp, and invigorating the liver and kidney is arranged, beneficial marrow, and effect such as make eye bright cures mainly soreness of waist and knee joint, passes out semen, quenches one's thirst, disease such as dripping urination and order are dark." book on Chinese herbal medicine converge with speech " be loaded with " Herba cuscutae is fictitious can be mended, in fact can in order to, cold can temperature, heat can be cool, wet can be dry, dry can the profit.The congenital foundation is kidney, kidney storing essence, gives birth to marrow, main bone, and liver governing tendons, kidney fill that then bone is strong, and liver fills that then muscle is strong, and song is stretched utilization, all belongs to muscle.Kidney storing essence master bone, blood stored in the liver master muscle, two through void, and then pain along the spinal column and vital essence are weary, and muscles and bones is soft and can not trample ground also, wind, cold, wet, hot evil multiple abscess meridians cause meridians to be stranded resistance, qi stagnation blood stasis, stagnation of QI and blood may bring about pain ".Caulis Spatholobi property hardship, sweet, warm is gone into the heart, spleen channel, and the energy relaxing muscles and tendons to promote blood circulation is controlled soreness of waist and knee joint, paralysis and numbness, menoxenia.Caulis Lonicerae is sweet, cold, can heat-clearing and toxic substances removing, collateral dredging, the rattan class is agile, easily easing joint movement and reach extremity.So with Semen Cuscutae, Caulis Spatholobi, Caulis Lonicerae invigorating the liver and kidney, beneficial marrow, bone and muscle strengthening, relaxing muscles and tendons to promote blood circulation, removing obstruction in the collateral to relieve pain is monarch drug altogether." book on Chinese herbal medicine converge with speech " point out " void of all parts of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the non-Cortex Eucommiae is not mended, the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, the non-Cortex Eucommiae is unfavorable, the acid of sufficient shin, the non-Cortex Eucommiae is not understood, the waist knee joint is painful, the non-Cortex Eucommiae is not removed." help kidney yang with Rhizoma Drynariae, Fructus Psoraleae, the Cortex Eucommiae, Radix Cyathulae, bone and muscle strengthening, dissipating blood stasis blood is more gone into kidney with the Radix Cyathulae priming, is ministerial drug altogether.Fructus Lycii is sweet, flat, goes into the Liver and kidney warp, and liver is moistened in nourishing kidney, and tonifying liver makes eye bright, the treating the liver deficiency of the kidney yin, and soreness of the waist and knees is had a dizzy spell, the many tears of blurred vision, cough due to consumptive disease, seminal emission is quenched one's thirst, " Treatise on Dietetic Therapy " year Fructus Lycii " hard muscle is anti-old, removes wind, tonification muscles and bones, and the beneficial people of energy removes asthenia.Fructus Lycii can make gas fill, and blood can be mended, Yang Kesheng, and the moon can be grown, and fire can fall, and rheumatism can be gone, and perfect magical effect is arranged here." the Zhang Jingyue cloud: " kind YANG invigorating person must be in treating YANG within YIN, then positive cloudy helping and biochemical infinite; Kind nourishing YIN person must be in treating YIN within YANG, then YIN matched with sufficient YANG making living things fully vivid." Gu Zuo is with Fructus Lycii, Fructus Ligustri Lucidi, Herba Ecliptae invigorating the liver and kidney, nourishing YIN and benefiting blood, treating YIN within YANG, treating YANG within YIN, yin nourishing blood is with coordination of potent and mild therapies.The Cortex Acanthopancis wind-damp dispelling, strengthening bone and muscle, blood circulation promoting and blood stasis dispelling." herbal justice " meaning " medicine of Radix Angelicae Pubescentis dispelling wind and removing obstruction in the collateral ... can declare logical hundred arteries and veins, the mediation meridians lead to muscles and bones and sharp joint ... so be the essential medicine of the soft big disease of migratory arthralgia flaccidity." its gas of Radix Puerariae is frivolous, can uply control headache, stiffness of the nape, pain along the spinal column, and osteodynia person all over, the priming power sick institute that go directly, three medicines and with making of calling.Because the present invention adopts said medicine to make up, all medicine compatibilities, monarch is coordinated mutually, on reach top top, in to back, down to ankle, walk crosswise support arm, easing joint movement and reach the extremity bones of the body collectively has liver and kidney tonifying, strong muscles and bones, nourishing YIN and benefiting blood, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the function of removing obstruction in the collateral to relieve pain can stop or delay the generation of bone matrix hyperplasia effectively, alleviates or eliminate the various incompatibility symptoms of bone matrix hyperplasia.Its pathological process of bone matrix hyperplasia is a carrying out property and irreversible, and therefore anti-overweighting controlled, to reach the effect of effective prevention and treatment bone matrix hyperplasia.
According to the herbal mediciment that such scheme is made, by all medicine compatibilities, monarch is coordinated mutually, on reach top top, in to back, down to ankle, walk crosswise support arm, easing joint movement and reach the extremity bones of the body collectively has liver and kidney tonifying, strong muscles and bones, nourishing YIN and benefiting blood, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the function of removing obstruction in the collateral to relieve pain can stop or delay the generation of bone matrix hyperplasia effectively, alleviates or eliminate the various incompatibility symptoms of bone matrix hyperplasia.This medicament is applicable to the treatment bone matrix hyperplasia, rheumatism, rheumatoid arthritis, femur head necrosis, cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, sciatica, various osteopathia such as osteoporosis and the sclerotin disunion of fracture back are effective composition of medicine of prevention and treatment bone matrix hyperplasia, it is remarkable that this medicament has therapeutic effect, treating both the principal and secondary aspects of a disease, cure rate height, relapse rate is low, has no side effect taking convenience, with low cost, the patient is easy to advantages such as acceptance.
The specific embodiment
The present invention is used for the treatment of the herbal mediciment of bone matrix hyperplasia, be to be got through the long term test institute by the inventor, its each component medical material all can be received better therapeutic effect in following weight portion ratio range: 30～90 parts of Semen Cuscutae, 30～90 parts of Caulis Spatholobis, 30～90 parts of Caulis Loniceraes, 20～60 parts of Rhizoma Drynariae, 20～60 parts of Fructus Psoraleaes, 20～60 parts of the Cortexs Eucommiae, 20～60 parts of Radix Cyathulaes, 15～35 parts of Fructus Lycii, 15～35 parts of Fructus Ligustri Lucidi, 15～35 parts of Herba Ecliptaes, 10～30 parts of Cortex Acanthopanciss, 10～30 parts of Radix Puerariaes, 10～30 parts of Radix Angelicae Pubescentiss.
Embodiment 1
The present invention treats the Chinese herbal medicine of bone matrix hyperplasia, and the weight portion proportioning of its each component medical material can be: 30 parts of Semen Cuscutae, 30 parts of Caulis Spatholobis, 30 parts of Caulis Loniceraes, 20 parts of Rhizoma Drynariae, 20 parts of Fructus Psoraleaes, 20～60 parts of the Cortexs Eucommiae, 20 parts of Radix Cyathulaes, 15 parts of Fructus Lycii, 15 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 10 parts of Cortex Acanthopanciss, 10 parts of Radix Puerariaes, 10 parts of Radix Angelicae Pubescentiss.
The preparation method of this herbal mediciment is: get above-mentioned each component Chinese herbal medicine and clean respectively and dry, remove impurity, and earlier the medicine that Caulis Spatholobi, Caulis Lonicerae, the Cortex Eucommiae and Radix Cyathulae are difficult for pulverizing is decocted according to a conventional method by described proportioning, produce concentrated medicament, again all the other each component pulverizing medicinal materials are crossed 150～200 mesh sieves and make powder,, dry sterilizing then with the concentrated medicament uniform mixing, incapsulate or make according to a conventional method the watered pill and get final product, also can be made into tablet or granule.
This herbal mediciment is applicable to the treatment bone matrix hyperplasia, rheumatism, rheumatoid arthritis, femur head necrosis, cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, sciatica, diseases such as osteoporosis and the sclerotin disunion of fracture back.When taking, can be according to state of an illness weight, take 6～8 grams every day, divides 2～3 times oral, 30 days is a course of treatment, the interval is 3 days between two courses of treatment, diet Semen phaseoli radiati, raw food, pungent greasy food during taking.
Embodiment 2
The present invention treats the Chinese herbal medicine of bone matrix hyperplasia, and the weight portion proportioning of its each component medical material can be: 55 parts of Semen Cuscutae, 55 parts of Caulis Spatholobis, 55 parts of Caulis Loniceraes, 40 parts of Rhizoma Drynariae, 40 parts of Fructus Psoraleaes, 40 parts of the Cortexs Eucommiae, 40 parts of Radix Cyathulaes, 25 parts of Fructus Lycii, 25 parts of Fructus Ligustri Lucidi, 25 parts of Herba Ecliptaes, 20 parts of Cortex Acanthopanciss, 20 parts of Radix Puerariaes, 20 parts of Radix Angelicae Pubescentiss.
The preparation of this herbal mediciment and instructions of taking are identical with embodiment 1.
Embodiment 3
The present invention treats the Chinese herbal medicine of bone matrix hyperplasia, and the weight portion proportioning of its each component medical material can be: 90 parts of Semen Cuscutae, 90 parts of Caulis Spatholobis, 90 parts of Caulis Loniceraes, 60 parts of Rhizoma Drynariae, 60 parts of Fructus Psoraleaes, 60 parts of the Cortexs Eucommiae, 60 parts of Radix Cyathulaes, 35 parts of Fructus Lycii, 35 parts of Fructus Ligustri Lucidi, 35 parts of Herba Ecliptaes, 30 parts of Cortex Acanthopanciss, 30 parts of Radix Puerariaes, 30 parts of Radix Angelicae Pubescentiss.
The preparation of this herbal mediciment and instructions of taking are identical with embodiment 1.
The inventor since two thousand two accepts out-patient's 400 examples for medical treatment, and the patient is divided into two groups at random, and 260 examples are organized in treatment, give Drug therapy of the present invention, and matched group 140 examples have Drug therapy; Wherein minimum 25 years old of age, maximum 70 years old, the course of disease is the shortest 1 year, and was the longest 20 years, and clinical observation is the shortest 1 month, and is the longest 1 year.Two groups of patients are in mean age, the course of disease, the state of an illness, and are basic identical, have comparability.
Diagnostic criteria: the card diagnosis criterion of therapeutical effect of all curing the desease among People's Republic of China's Chinese medicine industry standard of case with reference to State Administration of Traditional Chinese Medicine's issue is determined diagnosis.
Therapeutic Method: Therapeutic Method is under the voluntary prerequisite of patient, the patient is divided into two groups at random, 260 examples are organized in treatment, take Drug therapy of the present invention, every days 6～8 gram divide 2～3 times oral, be a course of treatment January, as not more drug withdrawal took again next course of treatment in 3 days, minimum taking for 1 course of treatment took for 6 courses of treatment at most; Matched group 140 examples are taken existing Drug therapy, and every day 2～3 times, minimum taking for 1 course of treatment took for 6 courses of treatment at most.
Efficacy assessment standard:
Clinical cure: sings and symptoms disappears, and vertebra and joint motion are normal, does not have recurrence in 3 years.
Produce effects: sings and symptoms disappears, and vertebra and joint motion are normal substantially, has the uncomfortable back of having a rest of slight neck, shoulder or waist lower limb to take a turn for the better when tired.
Invalid: pain does not alleviate, and symptom is not improved.
5, interpretation of result (seeing Table 1)
Table 1 liang group Comparison of therapeutic table
As can be seen from Table 1, treatment group curative effect obviously is better than matched group, and its total effective rate, cure rate (95.4%, 58.5%) are all apparently higher than matched group (75.7%, 38.6%).
Model case 1
Lee, the woman, 65 years old, Tanghe County, Henan Province king collects the village people, first visit on January 20 in 2004, readme cervical vertebra medical history 6 years, neck, the back of the body, arm, finger pain numbness, companioned with headache, dizziness, tinnitus check that through the X ray film making cervical curvature becomes straight C3-4, C4-5, the C5-6 front and rear edge is all seen obvious hypertrophy, spinal canal stenosis.Be diagnosed as hyperosteogeny of cervical vertebra (myeloid form).After two courses of treatment, symptom and sign disappears, and follows up a case by regular visits to and does not see recurrence in 3 years with Drug therapy of the present invention.
Model case 2
Zhao, woman, 60 years old, Bu Jiang Zhen Jianghe people from village, Tongbo County, on March 18th, 2004 went to a doctor.It is surplus that patient's dizziness, headache, two upper limb numbness, two weakness of the lower extremities are seemingly stepped on Cotton Gossypii sense 2 years, dizziness and tinnitus during severe symptoms, can not get up, moving then nausea and vomiting, tenderness by the palpation vertebra.The X-ray sheet shows that it is straight that the physiology curvature becomes, C4-5 vertebral body trailing edge hyperosteogeny, and strong, the limitation of activity of cervical region revolves neck and levies the positive, through taking medicine of the present invention symptom and sign elimination after three courses of treatment, follows up a case by regular visits to not recurrence in 2 years.
Model case 3
Zhang, man, 65 years old, port, Tongbo County, Henan Province people from village of Jiang Zhengao stockaded village come to go to a doctor 2005 days 5.1 year cause of patient is shouldered weight and lumbago occurred, and companion's right lower extremity radiating pain is not felt any better through Comprehensive Treatments such as clothes Chinese medicine and western medicine, physical therapys, with coming here to go to a doctor.Check: vertebra is lateral bending to the right, and the lumbar vertebra prolapse exists between waist L3/4-L5S1 spinous process and all there is tenderness the both sides, the waist limitation of activity, and left-handed or dextrorotation bacterium is 15 degree, it is positive that straight lower limb is raised experiment; CT shows that (1) L4/5 intervertebral disc is right back slight outstanding, and gently organizes shadow in the intervertebral foramina of right side; (2) L3/4-L5S1 intervertebral disk hernia; (3) L4/5 hyperosteogeny, L5S1 right side transverse process is big.The inventor advises its flat bed for sleeping in, gives Drug therapy of the present invention lumbago transference cure after 3 courses of treatment, and recurrence does not appear in 2 years patients of outpatient service check, and it is as usual to work and live.
Model case 4
High certain, woman, 40 years old, Nanyang Wancheng District people, went to a doctor on November 23rd, 2004, readme hyperosteogeny of cervical vertebra 3 years was from the beginning of left hand discontinuity pain numbness 1 year, recently both hands all often have numbness to suppress bloated pain, heavier to rise in night and morning, usually influence sleep, movable back is alleviated, over nearly three months the both sides cervical region stiff by force, ache, movable dumb.X-ray examination cervical vertebra 3-6 vertebral body hyperosteogeny, the physiology curvature changes; Diagnosis: hyperosteogeny of cervical vertebra (spondylotic radiculopathy).Drug administration of the present invention is the clinical disease recovery from illness after two courses of treatment, follows up a case by regular visits to and does not see recurrence in 2 years.
Model case 5
Huang, woman, 42 years old, area just outside a city gate people from town, Tongbo County, Henan Province, on July 29th, 2004 went to a doctor, it is surplus that rheumatoid arthritis 2 years is suffered from patient's readme, and with Drug therapys such as hormone, piroxicams, arthralgia alleviates in the outer court, but can't take care of oneself, the X sheet shows: two finger-joint gaps are narrower, and phalanges has distortion a little, and two handss have the osteoporosis phenomenon; Erythrocyte sedimentation rate: 68mm/h, RF:(+): ASO: greater than 300lu/ml; Diagnosis: rheumatoid arthritis.3 courses of treatment of oral medicine of the present invention, wrist, refer to, ankle, the gonalgia disappear, stiff improvement, hormone is also all removed, check erythrocyte sedimentation rate: 12mm/h ,-RF:(-); Be almost recovered.
Claims (1)
1, a kind of herbal mediciment for the treatment of bone matrix hyperplasia is characterized in that: it is formulated by the Chinese medicinal herbs of following weight portion: 30～90 parts of Semen Cuscutae, 30～90 parts of Caulis Spatholobis, 30～90 parts of Caulis Loniceraes, 20～60 parts of Rhizoma Drynariae, 20～60 parts of Fructus Psoraleaes, 20～60 parts of the Cortexs Eucommiae, 20～60 parts of Radix Cyathulaes, 15～35 parts of Fructus Lycii, 15～35 parts of Fructus Ligustri Lucidi, 15～35 parts of Herba Ecliptaes, 10～30 parts of Cortex Acanthopanciss, 10～30 parts of Radix Puerariaes, 10～30 parts of Radix Angelicae Pubescentiss.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013174812A1 (en) * | 2012-05-22 | 2013-11-28 | Nestec S.A. | Fructus ligustri lucidi for bones in young subjects |
| CN103768230A (en) * | 2014-02-08 | 2014-05-07 | 孙永国 | Traditional Chinese medicinal fumigation lotion for treating rheumatoid arthritis |
| CN104107272A (en) * | 2014-07-09 | 2014-10-22 | 逄海东 | Medicine composition for treating fracture |
| CN104147512A (en) * | 2014-07-30 | 2014-11-19 | 樊继绪 | Traditional Chinese medicine composition for treating wet and cold type sciatica |
| CN105477051A (en) * | 2014-11-27 | 2016-04-13 | 深圳市众安和生物科技有限公司 | Plant formulation capable of promoting bone metabolism |
| WO2022237873A1 (en) * | 2021-05-14 | 2022-11-17 | 天津中医药大学 | Pharmaceutical composition for preventing and treating osteoporosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4325237B2 (en) * | 2003-03-24 | 2009-09-02 | パナソニック株式会社 | Plasma display panel |
| CN100423744C (en) * | 2004-12-23 | 2008-10-08 | 张生全 | Medication for treating hyperosteogeny and complicating disease |
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2009
- 2009-10-10 CN CN2009101723736A patent/CN101664480B/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013174812A1 (en) * | 2012-05-22 | 2013-11-28 | Nestec S.A. | Fructus ligustri lucidi for bones in young subjects |
| CN103768230A (en) * | 2014-02-08 | 2014-05-07 | 孙永国 | Traditional Chinese medicinal fumigation lotion for treating rheumatoid arthritis |
| CN103768230B (en) * | 2014-02-08 | 2016-05-18 | 史红梅 | A kind of Chinese medicine fuming-lotion for the treatment of rheumatoid arthritis |
| CN104107272A (en) * | 2014-07-09 | 2014-10-22 | 逄海东 | Medicine composition for treating fracture |
| CN104107272B (en) * | 2014-07-09 | 2017-09-22 | 逄海东 | A kind of pharmaceutical composition for treating fracture |
| CN104147512A (en) * | 2014-07-30 | 2014-11-19 | 樊继绪 | Traditional Chinese medicine composition for treating wet and cold type sciatica |
| CN105477051A (en) * | 2014-11-27 | 2016-04-13 | 深圳市众安和生物科技有限公司 | Plant formulation capable of promoting bone metabolism |
| WO2022237873A1 (en) * | 2021-05-14 | 2022-11-17 | 天津中医药大学 | Pharmaceutical composition for preventing and treating osteoporosis |
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