CN101664038A - Bait for controlling sterilization of female pest rats - Google Patents
Bait for controlling sterilization of female pest rats Download PDFInfo
- Publication number
- CN101664038A CN101664038A CN200810198281A CN200810198281A CN101664038A CN 101664038 A CN101664038 A CN 101664038A CN 200810198281 A CN200810198281 A CN 200810198281A CN 200810198281 A CN200810198281 A CN 200810198281A CN 101664038 A CN101664038 A CN 101664038A
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- China
- Prior art keywords
- bait
- female
- percent
- rats
- bandicoot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000700159 Rattus Species 0.000 title abstract description 14
- 241000607479 Yersinia pestis Species 0.000 title abstract description 14
- 230000001954 sterilising effect Effects 0.000 title abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 title abstract description 4
- VKHAHZOOUSRJNA-GCNJZUOMSA-N mifepristone Chemical compound C1([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=CC=C(N(C)C)C=C1 VKHAHZOOUSRJNA-GCNJZUOMSA-N 0.000 claims abstract description 13
- 229960003248 mifepristone Drugs 0.000 claims abstract description 12
- 235000013336 milk Nutrition 0.000 claims abstract description 8
- 239000008267 milk Substances 0.000 claims abstract description 8
- 210000004080 milk Anatomy 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 8
- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 7
- 235000021307 Triticum Nutrition 0.000 claims abstract description 6
- 240000008042 Zea mays Species 0.000 claims abstract description 6
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 6
- 235000005822 corn Nutrition 0.000 claims abstract description 6
- 240000007594 Oryza sativa Species 0.000 claims abstract description 5
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 5
- 235000009566 rice Nutrition 0.000 claims abstract description 5
- 235000017060 Arachis glabrata Nutrition 0.000 claims abstract description 4
- 244000105624 Arachis hypogaea Species 0.000 claims abstract description 4
- 235000010777 Arachis hypogaea Nutrition 0.000 claims abstract description 4
- 235000018262 Arachis monticola Nutrition 0.000 claims abstract description 4
- 235000020232 peanut Nutrition 0.000 claims abstract description 4
- 244000068988 Glycine max Species 0.000 claims description 3
- 235000010469 Glycine max Nutrition 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 244000098338 Triticum aestivum Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 9
- 239000003814 drug Substances 0.000 abstract description 7
- 230000035935 pregnancy Effects 0.000 abstract description 7
- 241000209140 Triticum Species 0.000 abstract description 5
- 230000008901 benefit Effects 0.000 abstract description 3
- 235000019629 palatability Nutrition 0.000 abstract description 3
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- 241000266501 Ormosia ormondii Species 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 241000289702 Peramelidae Species 0.000 description 25
- 206010035148 Plague Diseases 0.000 description 9
- 230000008859 change Effects 0.000 description 6
- 238000005303 weighing Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 241000283984 Rodentia Species 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 241000282414 Homo sapiens Species 0.000 description 3
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Natural products C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- PXZAWHSJYIECNQ-UHFFFAOYSA-N apholate Chemical compound C1CN1P1(N2CC2)=NP(N2CC2)(N2CC2)=NP(N2CC2)(N2CC2)=N1 PXZAWHSJYIECNQ-UHFFFAOYSA-N 0.000 description 2
- -1 butanediol dicarboxylic acid esters Chemical class 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000000186 progesterone Substances 0.000 description 2
- 229960003387 progesterone Drugs 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 230000003559 chemosterilizing effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 208000021267 infertility disease Diseases 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 230000003397 luteinic effect Effects 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 229960001424 quinestrol Drugs 0.000 description 1
- PWZUUYSISTUNDW-VAFBSOEGSA-N quinestrol Chemical compound C([C@@H]1[C@@H](C2=CC=3)CC[C@]4([C@H]1CC[C@@]4(O)C#C)C)CC2=CC=3OC1CCCC1 PWZUUYSISTUNDW-VAFBSOEGSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000003128 rodenticide Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Landscapes
- Feed For Specific Animals (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention relates to a bait for controlling the sterilization of female pest rats, which is characterized by comprising the following components on the basis of total 100 mass percent: 0.005 to 0.05 percent of mifeprex, 0.1 to 1 percent of edible oil, 0.1 to 5 percent of edible sugar and/or milk powder and the balance of one of unhulled rice, rice, wheat, corn, yellow bean the pea nut. The bait for controlling sterilization of the female pest rats has the advantages of long-lasting control effect, no medicament resistance, high palatability, no environmental pollution, no safety hazard andthe like, is low in cost, simple in process, suitable to be promoted to control pest rat disaster in a large range and capable of reducing the population quantity of pest rats by over 80 percent within 6 months, reduces the pregnancy rate of female rates and even completely eradicates pregnant females.
Description
Invention field
The present invention relates to a kind of bait that kills mouse, relate to a kind of novel sterile bait that kills mouse of the female bandicoot of control specifically.
Background technology
China is a developing country that the plague of rats is very serious, and the plague of rats has not only endangered the production and operation of industry-by-industry, and tens kinds of Amphixenosises that propagated by the plague of rats are threatening human beings'health especially constantly.Why the plague of rats is difficult to control, mainly be because bandicoot fertility is extremely strong, after the experience short-term is killed on a large scale, killing the food in district and space resources still can provide safeguard for the individual breeding of moving into of remaining mouse and border, cause the bandicoot population to recover original quantity in the short period of time again, even finally surpassed original level.
Early stage protection against rodents control evil mainly depends on various physics and kills mouse and the protection against rodents apparatus, and various chemical deratization medicines etc.But, the implementation cost height that physics kills mouse is big to the manpower and materials demand, ageing poor with continuation.Then toxicity is big for the chemical deratization medicine of instant effect, and continuation is poor, and harm is big, and some chemical deratization medicine has also caused serious pollution to environment, causes non-target biotoxications such as bandicoot natural enemy, domestic animal even the mankind.At the beginning of the fifties in last century, the appearance of anticoagulation class rodent poison bait has solved the problem that much kills mouse, but only depends on single anticoagulant can not control the plague of rats fully.
At present, under the tactful situation about losing efficacy day by day of killing mouse of original " raising lethality ", the focus of plague of rats control research has accumulated on the strategy that kills mouse of " reduction fertility-rate ", and based on sterile control (Contraception control), promptly rely on some technology and method to make male or female bandicoot sterile (or sterilization), or hinder that its embryo nidation is grown and the young grows, with this fertility-rate that reduces bandicoot, control quantity and the density of its population.Theoretically, apholate is more safer than chemical rodenticide, pollutes for a short time even pollution-free, and biggest advantage is that control action is lasting, and effect is more remarkable when the bandicoot low-density.But because human early stage industrial technology is immature, the cost of apholate is on the contrary than general hypertoxic rodent poison bait height, and the medicine that can put on market also only has two kinds of male chemosterilants of the pure and mild butanediol dicarboxylic acid esters of alpha-chloro, and effect is barely satisfactory.But through domestic and international research in recent years to family planning, and be used for the hormone of human genital regulating and the maturation of chaff interference production technology, add the marriage system that it is found that bandicoot and mostly be the system of handing over of mixing, carry out sterile control and can play the control effect of taking away the firewood under the cauldron female, thereby filter out the female sterile medicine that some are applicable to bandicoot control, as quinestrol and progesterone compound etc.
Mifepristone (mifepristone, RU486) be a kind of lutern antagonist, significant feature mechanism is the recipient of blocking-up progesterone, suppress luteinic activity to reach the effect of terminal pregnancy, can bring into play sterile effect in a plurality of stages of female reproduction, cause sterile effects such as infertile, pregnancy termination, miscarriage and stillborn foetus.But also mifepristone is not used to control at present sterile report of bandicoot and patent.
Summary of the invention
The objective of the invention is to utilize mifepristone to develop and a kind ofly can control the sterile bait that kills mouse of female bandicoot effectively.
We are by being mixed into mifepristone in the bait, and the bait that obtains is to the bandicoot good palatability, and the edible back of female bandicoot pregnancy rate is low, and population quantity obviously descends, thereby has realized purpose of the present invention.
The bait that kills mouse that the female bandicoot of control of the present invention is sterile, it is characterized in that it always forms by mass fraction 100%, form by following compositions: mifepristone 0.005%～0.05%, edible oil 0.1%～1%, sugar and/or milk powder 0.1%～5% and its surplus are a kind of in paddy, rice, wheat, corn, soya bean or the peanut.
Under the environment of humidity, above-mentioned sugar can be used asccharin, and milk powder can replace with cream, to avoid the bait fermentation or to assemble insect
The preparation method of the bait that kills mouse that the female bandicoot of control of the present invention is sterile be after mifepristone, edible oil, sugar or asccharin and milk powder or cream are mixed in warm water again with paddy, rice, wheat, corn, soya bean or peanut in obtain a kind of the mixing.
The bait that kills mouse that the female bandicoot of control of the present invention is sterile is used for high density plague of rats district or when using first, take the intensive medicine of putting, saturated input, make bandicoot absorption capacity as much as possible bait in the scope of killing, be used for low-density plague of rats district or when reusing, can suitably disperse the dispensing point and reduce dosage, in addition, should in 30 days, carry out the secondary dispenser after first the use, can prolong the dosing interval time later on and reduce dosage.
Advantages such as the bait that kills mouse that the female bandicoot of control of the present invention is sterile has that the control effect is lasting, no pesticide resistance, good palatability, non-environmental-pollution and security risk, and it is with low cost, technology is simple, plague of rats control applies in being suitable on a large scale, the population quantity of bandicoot is descended more than 80%, and female mouse pregnancy rate reduces even does not have pregnant female body and occurs.
Embodiment
Following examples are to further specify of the present invention, are not limitations of the present invention.
Embodiment 1:
Take by weighing 985g paddy and be put in the container, take by weighing the 0.05g mifepristone, 10g edible oil, 4.95g sugar is mixed to be dissolved in the 100mL warm water, and again with the paddy mixing, normal temperature dries in the shade and obtains bait.
Bait is fixed a point to throw in for a long time in a large number: select two identical sealing fences of mouse density, throw in bait 5 places therein in the fence, the each 200g in every place, replenish weekly and throw in, another fence is not bait throwing in contrast, the number change of 1st month " Invest, Then Investigate " mouse, the result shows that the mouse population quantity comparison of testing fence descends 56% according to fence, investigate the pregnant situation of mouse after 3rd month once more, the bandicoot of experiment fence does not have the female body of gestation breeding and occurs, the number change of 6th month " Invest, Then Investigate " bandicoot, result show that the mouse population quantity comparison of testing fence descends 94% according to fence.
Embodiment 2:
Take by weighing the 988.85g wheat and be put in the container, take by weighing the 0.15g mifepristone, 10g edible oil, 1g milk powder is mixed to be dissolved in the 100mL warm water, and again with the wheat mixing, normal temperature dries in the shade and obtains bait.
Bait is fixed a point to throw in batches: select two identical sealing fences of mouse density, throw in bait 5 places therein in the fence, the each 100g in every place, replenish input once every 3 weeks, another fence is not bait throwing in contrast, the number change of 1st month " Invest, Then Investigate " mouse, the result shows that the mouse population quantity comparison of testing fence descends 60% according to fence, investigate the pregnant situation of mouse after 3rd month once more, the bandicoot of experiment fence does not have the female body of gestation breeding and occurs, the number change of 6th month " Invest, Then Investigate " bandicoot, result show that the mouse population quantity comparison of testing fence descends 82% according to fence.
Embodiment 3:
Take by weighing the 948.5g corn and be put in the container, take by weighing the 0.5g mifepristone, 1g edible oil, 10g milk powder, 40g sugar is mixed to be dissolved in the 100mL warm water, and again with the corn mixing, normal temperature dries in the shade and obtains bait.
Bait is carried out the multiple spot bulk storage: select two identical sealing fences of mouse density, throw in bait 8 places therein in the fence, the each 40g in every place, replenished in every month and throw in once, another fence is not bait throwing in contrast, and the number change of the 1st month " Invest, Then Investigate " mouse, result show that the mouse population quantity comparison of testing fence descends 64% according to fence, the number change of 6th month " Invest, Then Investigate " bandicoot, result show that the mouse population quantity comparison of testing fence descends 88% according to fence.
Claims (2)
1. bait that kills mouse, it is characterized in that it always forms by mass fraction 100%, form by following compositions: mifepristone 0.005%～0.05%, edible oil 0.1%～1%, sugar and/or milk powder 0.1%～5% and its surplus are a kind of in paddy, rice, wheat, corn, soya bean or the peanut.
2. a kind of bait that kills mouse according to claim 1 is characterized in that described sugar replaces with asccharin, and described milk powder replaces with cream.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810198281A CN101664038A (en) | 2008-09-03 | 2008-09-03 | Bait for controlling sterilization of female pest rats |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810198281A CN101664038A (en) | 2008-09-03 | 2008-09-03 | Bait for controlling sterilization of female pest rats |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101664038A true CN101664038A (en) | 2010-03-10 |
Family
ID=41800945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810198281A Pending CN101664038A (en) | 2008-09-03 | 2008-09-03 | Bait for controlling sterilization of female pest rats |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101664038A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102057926A (en) * | 2011-01-10 | 2011-05-18 | 广东省昆虫研究所 | Murine chemosterilant bait for inhibiting digenetic propagation |
| CN102113494A (en) * | 2011-01-10 | 2011-07-06 | 广东省昆虫研究所 | Rat sterility bait for inhibiting reproduction of female rats |
| CN103783052A (en) * | 2014-01-24 | 2014-05-14 | 河南科技大学 | Novel rodent sterile bait and preparation method thereof |
-
2008
- 2008-09-03 CN CN200810198281A patent/CN101664038A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102057926A (en) * | 2011-01-10 | 2011-05-18 | 广东省昆虫研究所 | Murine chemosterilant bait for inhibiting digenetic propagation |
| CN102113494A (en) * | 2011-01-10 | 2011-07-06 | 广东省昆虫研究所 | Rat sterility bait for inhibiting reproduction of female rats |
| CN102057926B (en) * | 2011-01-10 | 2013-05-22 | 广东省昆虫研究所 | A rodent sterility bait that inhibits sexual reproduction |
| CN103783052A (en) * | 2014-01-24 | 2014-05-14 | 河南科技大学 | Novel rodent sterile bait and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100310 |