CN101658602B - Drug for treating peripheral facial paralysis - Google Patents
Drug for treating peripheral facial paralysis Download PDFInfo
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- CN101658602B CN101658602B CN2009100752375A CN200910075237A CN101658602B CN 101658602 B CN101658602 B CN 101658602B CN 2009100752375 A CN2009100752375 A CN 2009100752375A CN 200910075237 A CN200910075237 A CN 200910075237A CN 101658602 B CN101658602 B CN 101658602B
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- rhizoma
- scorpio
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Abstract
The invention relates to a drug for treating peripheral facial paralysis, which is a capsule prepared by the steps of evenly mixing giant typhonium rhizome, scorpion, ground beetle and stiff silkworm after being processed with earthworm, cicada slough, Chinese angelica, szechuan lovage rhizome, radix salviae miltiorrhizae, red paeony root, white paeony root, divaricate saposhnikovia root, common floweringquince fruit, grassleaf sweelflag rhizome and liquoric root, adding water for decoction, then concentrating into a thick paste, drying, smashing, packaging in capsules and carrying out sterilization and disinfection. The drug has the effects of dispelling pathogenic wind, reducing phlegm, promoting blood circulation, removing blood stasis, dredging channels and activating collaterals, is used for treating the peripheral facial paralysis and is characterized by actual efficacy, rapidness, convenience and safe administration, and the clinical observation shows that the total effective rate is 100%.
Description
Technical field
The present invention relates to the bullate medicine of a kind of treatment infranuclear facial palsy, particularly relating to a kind of is the medicine of the treatment infranuclear facial palsy of crude drug preparation with Chinese medicine.
Background technology
Infranuclear facial palsy claims peripheral facial inflammation, peripheral facial paralysis again, is the empty interior facial root inflammation of a kind of acute apyetous stem breast.Its etiology unknown, modern medicine think with suffer from cold, factor such as viral infection and autonomic nerve instability is relevant.This disease onset is rapid, and patients more than half caused nervus facialis seriously to benumb in 48 hours, and symptom peaks in general 1 week.Main clinical manifestation is that the Ipsilateral face is amimia, the forehead wrinkle disappears, palpebral fissure enlarges, smooth, the ptosis of labial angle of nasolabial fold.Sick side can not be done and frown, the wrinkle volume, close order, grinningly, air-blowing, action such as whistle, often with shed tears, sialorrhea, food is detained between sick side cheek and gums, can occur hypogeusia or hyperacusis sometimes, even external auditory meatus herpes etc.
The western medical treatment infranuclear facial palsy adopts vasodilation, adrenocortical hormone, vitamin B1, B12, adenosine triphosphate, coenzyme A, cell growth peptide BFGF and physical therapy etc., the capable facial nerve decompression operative treatment of severe patient more at present.The expectant treatment effect often is difficult to certainly, and operative treatment has a big risk, and the patient is difficult to accept, and is difficult to fundamentally thoroughly to solve the left facial hemiparalysis of infranuclear facial palsy patient, sheds tears, symptom such as sialorrhea.
Summary of the invention
The purpose of this invention is to provide a kind of medicine that is used for the treatment of infranuclear facial palsy, this medicine has dispelling pathogenic wind and eliminating phlegm, blood circulation promoting and blood stasis dispelling, the effect of dredge the meridian passage, the treatment infranuclear facial palsy can play treating both the principal and secondary aspects of a disease, and drug effect is rapid, the purpose that therapeutic effect is good.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Scorpio 5～15 Bombyx Batryticatus 10～20
Eupolyphaga Seu Steleophaga 8～20 Pheretimas 8～20
Rhizoma Typhonii 5～15 Periostracum Cicadaes 5～15
Radix Angelicae Sinensis 10～30 Rhizoma Chuanxiongs 8～20
Radix Salviae Miltiorrhizae 10～30 Radix Paeoniae Rubra 10～30
The Radix Paeoniae Alba 10～30 Radix Saposhnikoviaes 8～20
Fructus Chaenomelis 8～20 Rhizoma Acori Graminei 8～20
Radix Glycyrrhizae 3～10.
Further, medicine of the present invention is that crude drug makes by following parts by weight of traditional Chinese medicines:
Scorpio 6 Bombyx Batryticatus 12
Eupolyphaga Seu Steleophaga 10 Pheretimas 12
Rhizoma Typhonii 8 Periostracum Cicadaes 8
Radix Angelicae Sinensis 15 Rhizoma Chuanxiongs 12
Radix Salviae Miltiorrhizae 15 Radix Paeoniae Rubra 15
The Radix Paeoniae Alba 12 Radix Saposhnikoviaes 10
Fructus Chaenomelis 15 Rhizoma Acori Graminei 12
Radix Glycyrrhizae 5.
Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a capsule.
The concrete preparation method of medicine of the present invention being made capsule is:
Rhizoma Typhonii is soaked in water to the interior no dried heart, decocts with the Rhizoma Zingiberis Recens smashed to pieces, Alumen and suitable quantity of water and taste pepperyly slightly to mouth, taking out dries in the air to sixty percent does cut into serving pieces; Scorpio, Eupolyphaga Seu Steleophaga is even with yellow wine companion respectively, fry to little take out when yellow dry standby; Bombyx Batryticatus preparata to little oil spilling, is fried once after the spray vinegar again, taken out after vexed half an hour and dry.
To cook Rhizoma Typhonii, Scorpio, Eupolyphaga Seu Steleophaga and Bombyx Batryticatus and Pheretima, Periostracum Cicadae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Saposhnikoviae, Fructus Chaenomelis, Rhizoma Acori Graminei, Radix Glycyrrhizae according to above-mentioned parts by weight mix homogeneously, decoct with water 2～4 times, each 1～2 hour, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.1～1.3, after 50～60 ℃ of dryings, be ground into 100～120 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
Infranuclear facial palsy belongs to categories such as Chinese medicine " facial paralysis ", " facial hemiparalysis ", how because of positive QI-insufficiency, venation inanition, weakened defensive QI, ailment said due to cold or exposure are taken advantage of a weak point in opponent's defence into apoplex involving the channels and collaterals, cause the resistance of QI and blood numbness, the few sun of face, Yangming Channel muscle lose in moistening foster, so that vertical delaying of muscle do not receive and send out.Control suitable dispelling pathogenic wind and eliminating phlegm, blood circulation promoting and blood stasis dispelling, dredge the meridian passage.In the prescription of the present invention, the hot temperature of Rhizoma Typhonii, dispelling pathogenic wind and eliminating phlegm is good at the wind of controlling women's head-ornaments; Scorpio, Bombyx Batryticatus can be expellingged wind and relieving convulsion; Rhizoma Acori Gramineiization is turbid eliminates the phlegm resuscitation inducing and mind tranquilizing; Light clear liter of Periostracum Cicadae loose, and is apt to away myocutaneous junction, site where the skin and muscle are joined, the heresy of energy dispelling wind and heat pathogens; Radix Saposhnikoviae is the panacea that dispels the wind, can expelling wind and cold pathogens, and again can dispelling wind and heat pathogens; The Pheretima clearing away heat and relieving the wind syndrome, dredge the meridian passage; The Eupolyphaga Seu Steleophaga removing blood stasis; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, dredge the meridian passage; The Radix Paeoniae Alba, Fructus Chaenomelis relaxing muscles and tendons and activating QI and blood in the collateral; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicines share, and play dispelling pathogenic wind and eliminating phlegm altogether, blood circulation promoting and blood stasis dispelling, and the merit of dredge the meridian passage is used for the treatment of the infranuclear facial palsy curative effect really, rapidly, conveniently, takes safety.
For further investigating the clinical efficacy and the safety of medicine of the present invention, select 200 routine infranuclear facial palsy patients that the curative effect of medicine of the present invention has been carried out clinical observation.
Among the 200 routine patients, male 89 examples, women 111 examples, 14～70 years old age, average 47.2 years old, the course of disease 1～32 day, average 14.7 days.
Diagnostic criteria: Ipsilateral volume stricture of vagina disappears, widening of palpebral fissure, shed tears, nasolabial fold shoals, ptosis of labial angle, can not do the wrinkle volume, frown, close order, the drum cheek, action such as whistle.Before the mastoid process tenderness can be arranged.Is central facial palsy as facial hemiparalysis with the hemiplegia symptom, does not include scope in case.
Therapeutic Method: oral medicine of the present invention, 1 time 3,3 times on the 1st, 10 days is 1 course of treatment.Take 3 courses of treatment altogether.
Efficacy assessment standard:
Recovery from illness: sings and symptoms all disappears, and the facial muscle functional rehabilitation is normal; Produce effects: sings and symptoms disappears substantially, need examine to find that facial muscle is unusual; Take a turn for the better: outward appearance is normal when static, and it is slight sagging or catacleisis is slow slightly to laugh at the bicker of seasonal disease side; Invalid: sings and symptoms does not have any variation.
200 routine patients cure 160 examples (80.0%), produce effects 26 examples (13.0%), 14 examples that take a turn for the better (7.0%), invalid 0 example, total effective rate 100% after treatment.
The specific embodiment
Embodiment 1
Getting Rhizoma Typhonii 400g is soaked in water a few days, change water every day 2～3 times, as spume, add when changing water Alumen a little with anticorrosion, steep again and changed water on the 1st, bubble takes out during to the interior no dried heart, put into pot, add Rhizoma Zingiberis Recens, Alumen and the water smashed to pieces and decoct in right amount, boil taste to mouth peppery slightly, taking-up is dried in the air to sixty percent and is done cut into serving pieces; It is even that Scorpio 300g, Eupolyphaga Seu Steleophaga 500g are added the yellow wine companion respectively, puts into pot, and taking-up is dried standby when frying to light yellow complexion with slow fire; When Bombyx Batryticatus 600g is put into pot and fries extremely little oil spilling, spray into vinegar and fry again once, add pot cover and take out after vexed half an hour and dry.
To cook Chinese medicine and Pheretima 600g, Periostracum Cicadae 400g, Radix Angelicae Sinensis 750g, Rhizoma Chuanxiong 600g, Radix Salviae Miltiorrhizae 750g, Radix Paeoniae Rubra 750g, Radix Paeoniae Alba 600g, Radix Saposhnikoviae 500g, Fructus Chaenomelis 750g, Rhizoma Acori Graminei 600g, Radix Glycyrrhizae 250g mix homogeneously, decoct with water 3 times, each 2 hours, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.2, after 60 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
Embodiment 2
Getting Rhizoma Typhonii 480g is soaked in water a few days, change water every day 2～3 times, as spume, add when changing water Alumen a little with anticorrosion, steep again and changed water on the 1st, bubble takes out during to the interior no dried heart, put into pot, add Rhizoma Zingiberis Recens, Alumen and the water smashed to pieces and decoct in right amount, boil taste to mouth peppery slightly, taking-up is dried in the air to sixty percent and is done cut into serving pieces; It is even that Scorpio 360g, Eupolyphaga Seu Steleophaga 600g are added the yellow wine companion respectively, puts into pot, and taking-up is dried standby when frying to light yellow complexion with slow fire; When Bombyx Batryticatus 720g is put into pot and fries extremely little oil spilling, spray into vinegar and fry again once, add pot cover and take out after vexed half an hour and dry.
To cook Chinese medicine and Pheretima 720g, Periostracum Cicadae 480g, Radix Angelicae Sinensis 900g, Rhizoma Chuanxiong 720g, Radix Salviae Miltiorrhizae 900g, Radix Paeoniae Rubra 900g, Radix Paeoniae Alba 720g, Radix Saposhnikoviae 600g, Fructus Chaenomelis 900g, Rhizoma Acori Graminei 720g, Radix Glycyrrhizae 300g mix homogeneously, decoct with water 3 times, each 1.5 hours, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.25, after 50 ℃ of dryings, be ground into 100 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
Claims (2)
1. medicine that is used for the treatment of infranuclear facial palsy is a crude drug by the Chinese medicine of following portions by weight:
Scorpio 5～15 Bombyx Batryticatus 10～20
Eupolyphaga Seu Steleophaga 8～20 Pheretimas 8～20
Rhizoma Typhonii 5～15 Periostracum Cicadaes 5～15
Radix Angelicae Sinensis 10～30 Rhizoma Chuanxiongs 8～20
Radix Salviae Miltiorrhizae 10～30 Radix Paeoniae Rubra 10～30
The Radix Paeoniae Alba 10～30 Radix Saposhnikoviaes 8～20
Fructus Chaenomelis 8～20 Rhizoma Acori Graminei 8～20
Radix Glycyrrhizae 3～10
Adopt following preparation method to prepare:
Rhizoma Typhonii is soaked in water to the interior no dried heart, decocts with the Rhizoma Zingiberis Recens smashed to pieces, Alumen and suitable quantity of water and taste pepperyly slightly to mouth, taking out dries in the air to sixty percent does cut into serving pieces; Scorpio, Eupolyphaga Seu Steleophaga is even with yellow wine companion respectively, fry to little take out when yellow dry standby; Bombyx Batryticatus preparata to little oil spilling, is fried once after the spray vinegar again, taken out after vexed half an hour and dry;
To cook Rhizoma Typhonii, Scorpio, Eupolyphaga Seu Steleophaga and Bombyx Batryticatus and Pheretima, Periostracum Cicadae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Saposhnikoviae, Fructus Chaenomelis, Rhizoma Acori Graminei, Radix Glycyrrhizae according to above-mentioned parts by weight mix homogeneously, decoct with water 2～4 times, each 1～2 hour, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.1～1.3, after 50～60 ℃ of dryings, be ground into 100～120 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
2. the medicine that is used for the treatment of infranuclear facial palsy according to claim 1 is characterized in that the parts by weight of described each Chinese medicine are:
Scorpio 6 Bombyx Batryticatus 12
Eupolyphaga Seu Steleophaga 10 Pheretimas 12
Rhizoma Typhonii 8 Periostracum Cicadaes 8
Radix Angelicae Sinensis 15 Rhizoma Chuanxiongs 12
Radix Salviae Miltiorrhizae 15 Radix Paeoniae Rubra 15
The Radix Paeoniae Alba 12 Radix Saposhnikoviaes 10
Fructus Chaenomelis 15 Rhizoma Acori Graminei 12
Radix Glycyrrhizae 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100752375A CN101658602B (en) | 2009-08-25 | 2009-08-25 | Drug for treating peripheral facial paralysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100752375A CN101658602B (en) | 2009-08-25 | 2009-08-25 | Drug for treating peripheral facial paralysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101658602A CN101658602A (en) | 2010-03-03 |
| CN101658602B true CN101658602B (en) | 2011-05-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100752375A Expired - Fee Related CN101658602B (en) | 2009-08-25 | 2009-08-25 | Drug for treating peripheral facial paralysis |
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| CN (1) | CN101658602B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893294B (en) * | 2014-04-22 | 2015-11-11 | 谭展玉 | A kind of Chinese medicine composition for the treatment of peripheral facial paralysis |
| CN104547352A (en) * | 2015-01-27 | 2015-04-29 | 张小凤 | Pharmaceutical composition for treating facioplegia |
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2009
- 2009-08-25 CN CN2009100752375A patent/CN101658602B/en not_active Expired - Fee Related
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| CN101658602A (en) | 2010-03-03 |
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Granted publication date: 20110511 Termination date: 20110825 |