CN101632691A - Effervescing agent of geranium strictipes - Google Patents

Effervescing agent of geranium strictipes Download PDF

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Publication number
CN101632691A
CN101632691A CN200910094585A CN200910094585A CN101632691A CN 101632691 A CN101632691 A CN 101632691A CN 200910094585 A CN200910094585 A CN 200910094585A CN 200910094585 A CN200910094585 A CN 200910094585A CN 101632691 A CN101632691 A CN 101632691A
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Prior art keywords
radix
fructus
agent
rhizoma
geranium strictipes
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CN200910094585A
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Chinese (zh)
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阳瑞鸿
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Abstract

The invention relates to an effervescing agent of geranium strictipes, which belongs to the class of medicaments and health care products and comprises the components by weight portions: 12 to 18 portions of geranium strictipes extract powder, disintegrator comprising 15-30 portions of acid agent and 40 to 60 portions of alkali agent, 2 to 5 portions of lubricant, a flavouring agent and a toner being used for regulating tastes and colors and comprising 0 to 10 portions of sweetening agent, 0 to 5 portions of aromatizer, and the like. The geranium strictipes extract powder is prepared by the technologies of aqueous extract, spray drying and the like, and is prepared into an effervescing tablet of geranium strictipes by a direct powder compression method together with other assistant materials. The effervescing agent of geranium strictipes has the characteristics of convenient administration, high bioavailability, good mouth feel, easy acceptance and the like.

Description

Effervescing agent of geranium strictipes
Technical field
The present invention relates to a kind of effervescing agent of geranium strictipes, belong to medicine, health care products.
Background technology
Radix Geranii Strictipedis is a Southwest China national folk medicinal plants, other popular name Radix cynanchi wilfordii of the Mang cattle Seedling Geraniaceae of section Geranium Geranium Radix Geranii Strictipedis Geranium strictipes R.Knuth, Geranium strictipes R. Kunth (Lijing, Chuxiong, rich people), passeris montani saturati food Radix Sanguisorbae (Kunming), Radix Potentillae griffithii (Yuxi), white Radix Sanguisorbae (Chuxiong), Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Sanguis Draxonis, blood are through stumble (Qujing), the domestic distribution of the hundred major separating (Baoshan) Yunnan (most of area, Yunnan), habitat, Sichuan: grass slope, in the shrubbery, the using method root is used as medicine in the woods, and bitterness is slightly cold.Promoting digestion and invigorating the stomach, hemostasis and dysentery-stopping, invigorating blood circulation analgesia.Cure mainly dysentery, diarrhoea, internal hemorrhage, menorrhagia, gastropathy.Root is used as medicine, the middle regions of the Yunnan Province and the NW YUNNAN Yi nationality, distributed over Yunnan, Sichuan and Guizhou, and Bai nationality, Naxi uses.At present, the Radix Geranii Strictipedis preparation has only decoct, medicated wine, powder etc., can't satisfy the different crowd needs, has restricted the popularization development of this medicine.
Summary of the invention
Purpose of the present invention just provides a kind of novel form of Radix Geranii Strictipedis, provides convenience so as to the curative effect of enhancing Radix Geranii Strictipedis with for people take Radix Geranii Strictipedis.
The object of the present invention is achieved like this: a kind of effervescing agent of geranium strictipes can be folk prescription or compound recipe effervescing agent of geranium strictipes;
(1) the folk prescription effervescing agent of geranium strictipes is characterized in that: contain Radix Geranii Strictipedis effective ingredient and chance water and can produce the acid of carbon dioxide (effervescent), the preparation that alkaline constituents is formed.
(2) the compound recipe effervescing agent of geranium strictipes is characterized in that: contain the Radix Geranii Strictipedis effective ingredient and can produce the acid of carbon dioxide (effervescent), the preparation that alkaline constituents is formed with containing other edible, effective medicinal components and meeting water.
Effervescing agent of geranium strictipes is a kind of confession solid preparation for oral administration that water can produce bubble (being effervescent) and disintegrate rapidly rapidly of putting into.Be with a kind of or several organic acid (sour agent) and a kind of or several meet acid and can produce CO2Common composition of inorganic salt (alkaline agent), it is met waterishlogging and gives birth to the acid-base integration reaction and emits CO2And disintegrate.Effervescing agent of geranium strictipes has following characteristics as a kind of new formulation.
(1) its production, transportation, StorageThe Tibetan is a solid form, so have dosage of solid formulations accurately, characteristics such as steady quality, production automation degree height, cost be low, portable;
(2) effervescing agent of geranium strictipes is taken facing with before being made into liquid, and liquid preparation is easy to swallow, the bioavailability height so have, and to characteristics such as GI irritation are little;
(3) its disintegrate is made of sour agent and alkaline agent, and disintegration is powerful, can make the rapid disintegrate of medicine become fine particle and dissolving rapidly;
(4 effervescing agent of geranium strictipes are met the water generates bubble and seethed (being effervescent) up and down, and are interesting, satisfy people's curious psychology, are particularly useful for children taking;
(5) effervescing agent of geranium strictipes flavouring instant, user is easily accepted.
The exploitation effervescing agent of geranium strictipes has vast market prospect, and businessman also can obtain good economic benefit surely.
The specific embodiment
Effervescing agent of geranium strictipes is meant the effervescing agent of geranium strictipes that contains the Radix Geranii Strictipedis effective ingredient that uses effervescive production technology to process.The component of effervescing agent of geranium strictipes is mainly divided two parts:
A, Radix Geranii Strictipedis effective ingredient: the Radix Geranii Strictipedis effective ingredient can be from the former powder of various natural or artificial Radix Geranii Strictipedis, cell wall breaking powder, nano powder, active ingredient extract, chemical analysis separator, concentrate etc.; Also can contain other edible, medicinal active ingredient simultaneously.
The component of B, generation effervescent effect: can be disintegrating agent, lubricant etc.; In order to regulate taste, color, can also add seasoning, toner.
Two parts are pressed the desired content film-making or granulate get final product.
Embodiment:
One, preparation folk prescription Radix Geranii Strictipedis effervescent tablet
[set of dispense ratio]:
Tartaric acid 67.8g
Sodium bicarbonate 86.4g
Sodium carbonate 86.4g
Radix Geranii Strictipedis extract powder 63.0g
FEG6000 9.0g
Aspartame 2.9g
Flavoring orange essence 4.8g
Make 100
[preparation method]: by the said components proportioning
(1) spray-driedly obtain the airtight preservation of Radix Geranii Strictipedis extractum powder, tartaric acid is in 105 ℃ of dryings 2 hours, and sodium bicarbonate, sodium carbonate were respectively at 120 ℃ of dryings 2 hours, and pulverize separately is crossed 100 mesh sieves, airtight preservation; Aspartame and flavoring orange essence were pulverized 100 mesh sieves, and FEG6000 pulverized 140 mesh sieves, preserved standby in the exsiccator.In the preparation process control preparation ambient temperature and humidity respectively 25 ℃, below 45%;
(2) get Radix Geranii Strictipedis extract powder, tartaric acid mix homogeneously, by adding aspartame, flavoring orange essence mix homogeneously;
(3) sodium bicarbonate, sodium carbonate mix homogeneously are got powder;
(4) powder (2) is mixed with powder (3), add the abundant mixing of FEG6000;
(5) mixed-powder direct compression obtains 100 of Radix Geranii Strictipedis effervescent tablets.
Two, preparation compound recipe Radix Geranii Strictipedis effervescent tablet
Preparation compound recipe Radix Geranii Strictipedis effervescent tablet can be selected Radix Geranii Strictipedis extract powder and other one or more edibles; medicinal active ingredient material is formed compound recipe Radix Geranii Strictipedis effervescent tablet, as: Rhizoma Cibotii; bracken; Rhizoma Osmundae; Radix Et Rhizoma Rhei; Radix Polygoni Multiflori; Radix Achyranthis Bidentatae; Radix Cyathulae; Radix Phytolaccae; Radix Stellariae; Radix Pseudostellariae; Radix Clematidis; Radix Aconiti; Radix Aconiti Kusnezoffii; Radix Aconiti Lateralis Preparata; the Radix Paeoniae Alba; Radix Paeoniae Rubra; Rhizoma Coptidis; Rhizoma Cimicifugae; Radix Aristolochiae Fangchi; Radix Stephaniae Tetrandrae; Rhizoma Menispermi; Rhizoma Corydalis; Radix Isatidis; Radix Sanguisorbae; Radix Sophorae Flavescentis; Radix Sophorae Tonkinensis; Radix Puerariae; Radix Glycyrrhizae; the Radix Astragali; Radix Polygalae; Radix Ginseng; Radix Panacis Quinquefolii; Radix Notoginseng; the Radix Angelicae Dahuricae; Radix Angelicae Sinensis; Radix Angelicae Pubescentis; Rhizoma Et Radix Notopterygii; Radix Peucedani; Rhizoma Chuanxiong; Rhizoma Ligustici; Radix Saposhnikoviae; Radix Bupleuri; Radix Glehniae; Radix Gentianae; Radix Gentianae Macrophyllae; Radix Cynanchi Paniculati; Radix Arnebiae (Radix Lithospermi); Radix Salviae Miltiorrhizae; Radix Scutellariae; Radix Scrophulariae; Radix Rehmanniae; Rhizoma Picrorhizae; Radix Morindae Officinalis; Radix Rubiae; Radix Dipsaci; Radix Trichosanthis; Radix Platycodonis; Radix Codonopsis; Radix Adenophorae; the Radix Aucklandiae; Radix Vladimiriae; the Rhizoma Atractylodis Macrocephalae; Rhizoma Atractylodis; Radix Asteris; rhizoma sparganic; Rhizoma Alismatis; Rhizoma Cyperi; Rhizoma Arisaematis; the Rhizoma Pinelliae; Rhizoma Acori Graminei; the Radix Stemonae; Bulbus Fritillariae Cirrhosae; Bulbus Fritillariae Thunbergii; Rhizoma Polygonati; Rhizoma Polygonati Odorati; Radix Asparagi; Radix Ophiopogonis; Radix Liriopes; the Rhizoma Anemarrhenae; Rhizoma Dioscoreae; Rhizoma Belamcandae; Rhizoma Curcumae; Rhizoma Curcumae Longae; Radix Curcumae; Rhizoma Gastrodiae; Pseudobulbus Bletillae (Rhizoma Bletillae); Flos Magnoliae; Flos Sophorae; Flos Caryophylli; Flos Daturae; Flos Lonicerae; Flos Farfarae; Flos Chrysanthemi; Flos Carthami; Pollen Typhae; Stigma Croci; flavor; Semen Lepidii (Semen Descurainiae); Fructus Chaenomelis; Fructus Crataegi; Semen Armeniacae Amarum; Semen Persicae; Fructus Mume; Fructus Rosae Laevigatae; Semen Astragali Complanati; Semen Cassiae; Fructus Psoraleae; Fructus Aurantii; Fructus Evodiae; Fructus Crotonis; Semen Ziziphi Spinosae; Fructus Foeniculi; Fructus Cnidii; Fructus Forsythiae; Fructus Ligustri Lucidi; Semen Strychni; Semen Cuscutae; Semen Pharbitidis; Semen Hyoscyami; Fructus Lycii; Fructus Gardeniae; Fructus Trichosanthis; Fructus Carpesii; Fructus Arctii; Semen Coicis; Semen Arecae; Fructus Amomi; Fructus Amomi Rotundus; Fructus Alpiniae Oxyphyllae; Sargassum; Ganoderma; Poria; Polyporus; Usnea; Cacumen Platycladi; Folium Mori; Folium Polygoni Tinctorii; Folium Isatidis; Folium Eriobotryae; Folium Sennae; Folium Perillae; Caulis Aristolochiae Manshuriensis; Caulis Clematidis Armandii; Caulis Sargentodoxae; Ramulus Cinnamomi; Lignum Sappan; Caulis Spatholobi; Lignum Dalbergiae Odoriferae; Lignum Aquilariae Resinatum; Ramulus Uncariae Cum Uncis; Resina Ferulae; Benzoinum; Olibanum; Myrrha; Sanguis Draxonis; Cortex Mori; Cortex Moutan; Cortex Magnoliae Officinalis; Cortex Cinnamomi; the Cortex Eucommiae; Cortex Phellodendri; Cortex Acanthopancis; Cortex Fraxini; Cortex Periplocae; Cortex Lycii; Folium Pyrrosiae; Herba Ephedrae; Herba Asari; Herba Epimedii; Herba Violae; Herba Lysimachiae; Herba Pogostemonis; Herba Schizonepetae; the Herba Leonuri Herba Menthae; Herba Cistanches; Herba Andrographis; Herba Plantaginis; Herb Gynostemmae Pentaphylli; Herba Artemisiae Annuae; Herba Artemisiae Scopariae; Herba Taraxaci; Spora Lygodii; Indigo Naturalis; catechu; Borneolum Syntheticum; Galla Chinensis; Pheretima; Hirudo; Concha Haliotidis; Margarita; Concha Ostreae; Endoconcha Sepiae; Scorpio; Scolopendra; Eupolyphaga Seu Steleophaga; Ootheca Mantidis; Periostracum Cicadae; Mylabris; Bombyx Batryticatus; Hippocampus; Venenum Bufonis; Oviductus Ranae; Carapax Et Plastrum Testudinis; Carapax Trionycis; Gecko; money is white; Serpentis; Agkistrodon; Zaocys; Fel Ursi; Moschus; Cornu Cervi Pantotrichum; Calculus Bovis; Cornu Saigae Tataricae; Cinnabaris; Realgar; Pyritum; Haematitum; Arsenicum sablimatum; Calamina; Talcum; Gypsum Fibrosum; Natrii Sulfas; Flos Caryophylli; Fructus Anisi Stellati; Semen Canavaliae; Fructus Foeniculi; Herba Cirsii; Rhizoma Dioscoreae; Fructus Crataegi; Herba Portulacae; Zaocys; Fructus Mume; Fructus Chaenomelis; Fructus Cannabis; CitrusaurantiumL.Var.amara Engl.; Rhizoma Polygonati Odorati; Radix Glycyrrhizae; the Radix Angelicae Dahuricae; Semen Ginkgo; Semen Lablab Album; Flos Semen Lablab Album; Arillus Longan; Semen Cassiae; Bulbus Lilii; Semen Myristicae; Cortex Cinnamomi; Fructus Phyllanthi; Fructus Citri Sarcodactylis; Semen Armeniacae Amarum is (sweet; bitter); Fructus Hippophae; Concha Ostreae; Semen Euryales; Pericarpium Zanthoxyli; Semen Phaseoli; Colla Corii Asini; Endothelium Corneum Gigeriae Galli; Fructus Hordei Germinatus; Thallus Laminariae (Thallus Eckloniae); Fructus Jujubae (Fructus Jujubae; Ziziphi Spinosae; Fructus Jujubae); Fructus Momordicae; Semen Pruni; Flos Lonicerae; Fructus Canarii; Herba Houttuyniae; Rhizoma Zingiberis Recens (Rhizoma Zingiberis Recens; Rhizoma Zingiberis); Semen Hoveniae (Fructus Hoveniae); Fructus Gardeniae; Fructus Amomi; Semen Sterculiae Lychnophorae; Poria; Fructus Citri; Herba Moslae; Semen Persicae; Folium Mori; Fructus Mori; orange; Radix Platycodonis; Fructus Alpiniae Oxyphyllae; Folium Nelumbinis; Semen Raphani; Semen Nelumbinis; Rhizoma Alpiniae Officinarum; Herba Lophatheri; Semen Sojae Preparatum; Flos Chrysanthemi; Herba Cichorii; Semen Sinapis; Rhizoma Polygonati; Folium Perillae; Fructus Perillae; Radix Puerariae; Semen Sesami Nigrum; black pepper; the Flos Sophorae Immaturus; Flos Sophorae; Herba Taraxaci; Mel; Semen Torreyae; Semen Ziziphi Spinosae; fresh Rhizoma Imperatae; fresh Rhizoma Phragmitis; Agkistrodon halys; Pericarpium Citri tangerinae; Herba Menthae; Semen Coicis; Bulbus Allii Macrostemonis; Fructus Rubi; Herba Pogostemonis; Folium Ginseng; Herba Herminii; Radix Cirsii Japonici; Fructus Ligustri Lucidi; Fructus Corni; Radix Cyathulae; Bulbus Fritillariae Cirrhosae; Rhizoma Chuanxiong; Embryo cervi; cervus elaphus linnaeus; Cervus elaphus Linnaeas bone; Radix Salviae Miltiorrhizae; Cortex Acanthopancis; Fructus Schisandrae Chinensis; Rhizoma Cimicifugae; Radix Asparagi; Rhizoma Gastrodiae; Radix Pseudostellariae; Radix Morindae Officinalis; the Radix Aucklandiae; the Herba Equiseti Hiemalis; Fructus Arctii; Radix Arctii; Semen Plantaginis; Herba Plantaginis; Radix Glehniae; Bulbus Fritillariae Ussuriensis; Radix Scrophulariae; Radix Rehmanniae; Radix Polygoni Multiflori; Pseudobulbus Bletillae (Rhizoma Bletillae); the Rhizoma Atractylodis Macrocephalae; the Radix Paeoniae Alba; Fructus Amomi Rotundus; Concha Haliotidis; Herba Dendrobii; Cortex Lycii; Caulis Bambusae In Taenia; Flos Carthami; Radix Rhodiolae; Radix Panacis Quinquefolii; Fructus Evodiae; Radix Achyranthis Bidentatae; the Cortex Eucommiae; Folium Eucommiae; Semen Astragali Complanati; Cortex Moutan; Aloe; Rhizoma Atractylodis; Fructus Psoraleae; the Fructus Chebulae; Radix Paeoniae Rubra; Radix Polygalae; Radix Ophiopogonis; Carapax Et Plastrum Testudinis; Herba Eupatorii; Cacumen Platycladi; Radix et Rhizoma Rhei (processed); Radix Polygoni Multiflori Preparata; Radix Et Caulis Acanthopanacis Senticosi; rose hip; the Herba Lycopi; Rhizoma Alismatis; Flos Rosae Rugosae; Calyx Hibisci Sabdariffae; the Rhizoma Anemarrhenae; Herba Apocyni veneti; Folium Ilicis; Rhizoma Fagopyri Dibotryis; Fructus Rosae Laevigatae; Pericarpium Citri Reticulatae Viride; Cortex Magnoliae Officinalis; Flos Magnoliae Officinalis; Rhizoma Curcumae Longae; Fructus Aurantii; Fructus Aurantii Immaturus; Semen Platycladi; Margarita; Herb Gynostemmae Pentaphylli; Semen Trigonellae; Radix Rubiae; Fructus Piperis Longi; Semen Allii Tuberosi; Caulis Polygoni Multiflori; Rhizoma Cyperi; Rhizoma Drynariae; Radix Codonopsis; Cortex Mori; Ramulus Mori; Bulbus Fritillariae Thunbergii; Herba Leonuri; Herba Centellae; Herba Epimedii; Semen Cuscutae; Flos Chrysanthemi Indici; Folium Ginkgo; the Radix Astragali; Hupeh Fritillary Bulb; Folium Sennae; Gecko; Pericarpium Citri tangerinae; Fructus Sophorae; Pollen Typhae; Fructus Tribuli; propolis; Fructus Tamarindi Indicae; Herba Ecliptae; Radix Et Rhizoma Rhei; Radix Rehmanniae Preparata; Carapax Trionycis etc.Present embodiment is described in detail as the composition with the common use of Radix Geranii Strictipedis with Herba Dendrobii.
[set of dispense ratio]:
Tartaric acid 67.8g
Sodium bicarbonate 86.4g
Sodium carbonate 86.4g
Radix Geranii Strictipedis extract powder 33.0g
Herba Dendrobii extract powder 30.0g
FEG6000 9.0g
Aspartame 2.9g
Flavoring orange essence 4.8g
Make 100
[preparation method]: by the said components proportioning
(6) spray-driedly obtain Radix Geranii Strictipedis extractum powder, the airtight preservation of Herba Dendrobii extractum powder, tartaric acid is in 105 ℃ of dryings 2 hours, and sodium bicarbonate, sodium carbonate were respectively at 120 ℃ of dryings 2 hours, and pulverize separately is crossed 100 mesh sieves, airtight preservation; Aspartame and flavoring orange essence were pulverized 100 mesh sieves, and FEG6000 pulverized 140 mesh sieves, preserved standby in the exsiccator.In the preparation process control preparation ambient temperature and humidity respectively 25 ℃, below 45%;
(7) get Radix Geranii Strictipedis extract powder, Herba Dendrobii extract powder, tartaric acid be mixed even, by adding aspartame, flavoring orange essence mix homogeneously;
(8) sodium bicarbonate, sodium carbonate mix homogeneously are got powder;
(9) powder (2) is mixed with powder (3), add the abundant mixing of FEG6000;
(10) mixed-powder direct compression obtains 100 of Radix Geranii Strictipedis effervescent tablets.

Claims (1)

  1. Figure A2009100945850002C1
    A kind of effervescing agent of geranium strictipes can be folk prescription or compound recipe effervescing agent of geranium strictipes:
    Figure A2009100945850002C2
    The folk prescription effervescing agent of geranium strictipes is characterized in that: contain Radix Geranii Strictipedis effective ingredient and chance water and can produce the acid of carbon dioxide (effervescent), the preparation that alkaline constituents is formed.
    Figure A2009100945850002C3
    The compound recipe effervescing agent of geranium strictipes is characterized in that: contain the Radix Geranii Strictipedis effective ingredient and can produce the acid of carbon dioxide (effervescent), the preparation that alkaline constituents is formed with containing other edible, effective medicinal components and meeting water.
CN200910094585A 2009-06-16 2009-06-16 Effervescing agent of geranium strictipes Pending CN101632691A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068680A (en) * 2010-12-02 2011-05-25 韩世昌 Omphaloidean external medicament for treating enteritis and preparation method thereof
CN103251865A (en) * 2013-05-31 2013-08-21 吴萍 Traditional Chinese medicine composite for treating diarrhea
CN103520519A (en) * 2013-09-04 2014-01-22 刘祥义 Gastrodia elata submicron powder effervescent tablet and preparation method thereof
CN106798055A (en) * 2016-12-08 2017-06-06 曾琼 A kind of liver-protecting tea and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068680A (en) * 2010-12-02 2011-05-25 韩世昌 Omphaloidean external medicament for treating enteritis and preparation method thereof
CN103251865A (en) * 2013-05-31 2013-08-21 吴萍 Traditional Chinese medicine composite for treating diarrhea
CN103251865B (en) * 2013-05-31 2014-11-26 吴萍 Traditional Chinese medicine composite for treating diarrhea
CN103520519A (en) * 2013-09-04 2014-01-22 刘祥义 Gastrodia elata submicron powder effervescent tablet and preparation method thereof
CN106798055A (en) * 2016-12-08 2017-06-06 曾琼 A kind of liver-protecting tea and preparation method thereof

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Application publication date: 20100127