CN101622013A - 包含丁丙诺啡和纳洛酮的改善的药用组合物 - Google Patents

包含丁丙诺啡和纳洛酮的改善的药用组合物 Download PDF

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Publication number
CN101622013A
CN101622013A CN200880006847A CN200880006847A CN101622013A CN 101622013 A CN101622013 A CN 101622013A CN 200880006847 A CN200880006847 A CN 200880006847A CN 200880006847 A CN200880006847 A CN 200880006847A CN 101622013 A CN101622013 A CN 101622013A
Authority
CN
China
Prior art keywords
buprenorphine
naloxone
composition
administration
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880006847A
Other languages
English (en)
Chinese (zh)
Inventor
克利斯托弗·波恩·夏普利奥
尼尔·海德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Reckitt Benckiser Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt Benckiser Healthcare UK Ltd filed Critical Reckitt Benckiser Healthcare UK Ltd
Publication of CN101622013A publication Critical patent/CN101622013A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200880006847A 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物 Pending CN101622013A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0703967.0 2007-03-01
GB0703967A GB2447015A (en) 2007-03-01 2007-03-01 Analgesic composition comprising a specific ratio of buprenorphine and naltrexone

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012101207560A Division CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Publications (1)

Publication Number Publication Date
CN101622013A true CN101622013A (zh) 2010-01-06

Family

ID=37965734

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880006847A Pending CN101622013A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物
CN2012101207560A Pending CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2012101207560A Pending CN102670610A (zh) 2007-03-01 2008-02-15 包含丁丙诺啡和纳洛酮的改善的药用组合物

Country Status (16)

Country Link
US (1) US20100168147A1 (OSRAM)
EP (1) EP2114453A1 (OSRAM)
JP (1) JP2010520185A (OSRAM)
KR (1) KR20090115863A (OSRAM)
CN (2) CN101622013A (OSRAM)
AR (1) AR065581A1 (OSRAM)
AU (1) AU2008220573A1 (OSRAM)
BR (1) BRPI0807905A2 (OSRAM)
CA (1) CA2678675A1 (OSRAM)
CL (1) CL2008000610A1 (OSRAM)
GB (1) GB2447015A (OSRAM)
MX (1) MX2009009133A (OSRAM)
PE (1) PE20081874A1 (OSRAM)
TW (1) TW200836738A (OSRAM)
WO (1) WO2008104737A1 (OSRAM)
ZA (1) ZA200905691B (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550136B (zh) 2006-07-21 2016-04-13 生物递送科学国际公司 吸收增强的经粘膜递送装置
CN105833420A (zh) * 2008-06-23 2016-08-10 生物递送科学国际公司 多向粘膜给药装置及使用方法
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
ES2660116T3 (es) 2011-08-18 2018-03-20 Biodelivery Sciences International, Inc. Dispositivos mucoadhesivos resistentes al uso inadecuado para la administración de buprenorfina
EP2915525B1 (en) 2011-09-19 2021-08-11 Orexo AB Sublingual abuse-resistant tablets comprising buprenorphine and naloxone
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US20140275148A1 (en) * 2013-03-15 2014-09-18 Novus Pharma LLC Orally administrable, self-supporting dissolving film dosage forms
CA2875384A1 (en) 2013-12-20 2015-06-20 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
US9480644B2 (en) 2014-03-14 2016-11-01 Opiant Pharmaceuticals, Inc. Nasal drug products and methods of their use
US10085937B2 (en) 2014-03-14 2018-10-02 Adapt Pharma Limited Nasal drug products and methods of their use
US9561177B2 (en) 2014-03-14 2017-02-07 Adapt Pharma Limited Nasal drug products and methods of their use
RU2016136714A (ru) 2014-03-14 2018-04-19 ОПИАНТ ФАРМАСЮТИКАЛС, Инк. Назальные готовые лекарственные формы и способы их применения
US20250144015A1 (en) 2023-11-06 2025-05-08 Extrovis Ag Pharmaceutical Compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457933A (en) * 1980-01-24 1984-07-03 Bristol-Myers Company Prevention of analgesic abuse
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions
EP1041988A4 (en) * 1997-12-22 2002-03-13 Euro Celtique Sa METHOD FOR PREVENTING ABUSE OF OPIOID DOSES FORMS
AR031682A1 (es) 1999-11-19 2003-10-01 Reckitt Benckiser Helthcare Uk Composiciones farmaceuticas
US20050191340A1 (en) * 2002-08-09 2005-09-01 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
PT1526848E (pt) * 2002-08-09 2007-08-08 Gruenenthal Gmbh Antagonistas dos receptores de opióides em sistemas transdérmicos contendo buprenorfina
EP1584335A3 (en) * 2004-04-05 2006-02-22 Laboratorios Del Dr. Esteve, S.A. Active substance combination comprising a carbinol composition and an opioid
US8236751B2 (en) * 2007-03-07 2012-08-07 The Johns Hopkins University Methods of increasing muscle mass using follistatin-like related gene (FLRG)

Also Published As

Publication number Publication date
US20100168147A1 (en) 2010-07-01
WO2008104737A1 (en) 2008-09-04
CL2008000610A1 (es) 2008-09-05
CN102670610A (zh) 2012-09-19
GB2447015A (en) 2008-09-03
CA2678675A1 (en) 2008-09-04
MX2009009133A (es) 2009-09-03
JP2010520185A (ja) 2010-06-10
EP2114453A1 (en) 2009-11-11
BRPI0807905A2 (pt) 2014-06-17
KR20090115863A (ko) 2009-11-09
TW200836738A (en) 2008-09-16
AR065581A1 (es) 2009-06-17
ZA200905691B (en) 2010-10-27
PE20081874A1 (es) 2009-01-26
AU2008220573A1 (en) 2008-09-04
GB0703967D0 (en) 2007-04-11

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