CN101601729A - A kind of health product that is used for mastopathy and preparation method thereof - Google Patents
A kind of health product that is used for mastopathy and preparation method thereof Download PDFInfo
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- CN101601729A CN101601729A CNA2009100223367A CN200910022336A CN101601729A CN 101601729 A CN101601729 A CN 101601729A CN A2009100223367 A CNA2009100223367 A CN A2009100223367A CN 200910022336 A CN200910022336 A CN 200910022336A CN 101601729 A CN101601729 A CN 101601729A
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Abstract
The present invention relates to a kind of health product that is used for mastopathy and preparation method thereof.Mastopathy be women's commonly encountered diseases, frequently-occurring disease, for a long time control difficult, sickness rate is up to 80%, and in recent years, breast disease was in the peak period, and canceration rate is higher, and breast carcinoma is leapt to the first by several years ago the 5th on the ranking list of women's tumor becomes the No.1 killer of women's health.The present invention is made up of Radix Angelicae Sinensis, Flos Carthami, Retinervus Luffae Fructus, Fructus Forsythiae, Olibanum, Myrrha, Cortex Cinnamomi, Flos Caryophylli, Borneolum Syntheticum, the side in Radix Angelicae Sinensis, Flos Carthami promoting blood circulation to restore menstrual flow, pain relieving, be monarch drug; Retinervus Luffae Fructus dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain; The Fructus Forsythiae heat-clearing and toxic substances removing, the diffusing furuncle of detumescence is a ministerial drug; Olibanum, Myrrha promoting blood circulation and stopping pain, detumescence and promoting granulation; The Cortex Cinnamomi cold expelling is promoted blood circulation, and promoting blood circulation and stopping pain is an adjuvant drug; The Flos Caryophylli reinforcing the kidney and supporting YANG; The Borneolum Syntheticum refreshment of having one's ideas straightened out is just medicine.The present invention is rapid-action, and it is outstanding that effect is, and does not have obvious toxic and side effects.
Description
Technical field
The present invention relates to a kind of health product that is used for mastopathy and preparation method thereof.
Background technology
Mastitis are that the acute festering type of breast infects, by antibacterial (golden yellow staphylococcus etc.) is caused through nipple crowfoot cracks place or latex dust mouth intrusion mammary gland tissue, primary disease with the primipara for seeing more, good being sent out in the 3rd～4 week of puerperal, premorbid often has the nipple crowfoot cracks, the latent deformity of nipple, and breast is squeezed, inducements such as human milk silt are from the beginning of mammary swelling, pain, red and swollen, the heating in lump tenderness surface; As continue development, sx then, breast throbbing pain, severe patient is with hyperpyrexia, shiver with cold, and breast swell and pain is obvious, the local skin redness, scleroma, tenderness, the enlargement of Ipsilateral axillary lymph knot are arranged, and tenderness, inflammation are softening in a couple of days, the formation breast is swollen, and fluctuation is arranged, and skin rubefaction and fluctuation that abscess is dark are not obvious, clinical characters is anxious for morbidity, can be with heating, fear of cold, sick side breast red and swollen heat pain, lump occurs, form abscess etc. at last.
Cyclomastopathy is lump to occur and distending pain is that a kind of of main clinical manifestation is neither inflammation with breast, proliferative lesion that neither tumor, it is with the epithelial cell of mammary gland, acinus, conduit and connective tissue degeneration and the variation of carrying out property structurally, and the galactophore epithelial cell number increases to the general name of a class disease of basic pathology variation because of abnormal non-physiologic.Its basic pathology is characterized as: lump in breast, pain, many bilaterals, also can be one-sided, persistence suppress bloated pain, and be accompanied by spirit, the variation of psychological aspects, this phenomenon can not disappear along with the end in menstrual period, the women is in fatigue, angry, Changes in weather, breast is suppressed bloated during emotion changes, pain increases the weight of, and pain character is with distending pain, twinge, dull pain, scurry pain, dull pain, touch a tender spot, lancinating pain, the bright sample pain of fire etc., part patient has nipple to itch, discharge and bitter taste rib expand, uncomfortable in chest, anorexia, General Symptomies such as menoxenia, cyclomastopathy are the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy, should be the trend that rises year by year by the disease sickness rate in the last few years, age also more and more becomes younger, and has 70%～80% women that in various degree cyclomastopathy is all arranged according to investigations approximately, is more common in 25～45 years old women.
The traditional Chinese medical science thinks that breast and Liver and kidney two are the closest through relation, next is to dash wantonly two arteries and veins, stagnation of QI due to depression of the liver, feelings will internal injury have material impact in the pathogenic process of nodules of the breast, depressed emotion usually, the stagnation of QI is not relaxed, and QI and blood week loss degree pents up in breast stomach network, breast network meridian and vessels obstruction is obstructed, stagnation of QI and blood may bring about pain and cause mastalgia; Liver-QI transversely invading the stomach, dysfunction of the spleen in transportation, it is poly-for nuclear that the stagnant blood stasis of expectorant foul smell is held the expectorant knot under the arm, follows through staying poly-Ruzhong, so the Ruzhong caking, deficiency of the liver and kindey, Chong and Ren channel disorder also are the major reasons that causes nodules of the breast, and kidney is a source of vital essence of five ZANG-organs, kidney qiization is given birth to menses, and menses excites to dash appoints, and dashes and appoints a following uterus, on connect breast, the QI and blood of dash appointing, last behavior breast, following behavior warp, if deficiency of kidney-QI, Chong and Ren channel disorder, QI and blood stagnates, and the long-pending stasis of blood is gathered in breast, uterus or mastalgia and lump or disorderly imbalance of menses.
Summary of the invention
The object of the present invention is to provide a kind ofly has good therapeutic effect and does not have health product of obvious toxic-side effects and preparation method thereof mastopathy.
For achieving the above object, the technical solution used in the present invention is:
A kind of raw materials of effective components that is used for the health product of mastopathy forms and weight proportion is:
40～60 parts of 90～110 parts of Retinervus Luffae Fructuss of 90～110 parts of Flos Carthamis of Radix Angelicae Sinensis
10～30 parts of 10～30 parts of Myrrhas of 40～60 parts of Olibanums of Fructus Forsythiae
1～5 part of 3～8 parts of Borneolum Syntheticum of 5～15 portions of Flos Caryophyllis of Cortex Cinnamomi.
Above-mentioned a kind of raw materials of effective components that is used for the health product of mastopathy forms and weight proportion is:
50 parts of 100 parts of Retinervus Luffae Fructuss of 100 parts of Flos Carthamis of Radix Angelicae Sinensis
20 parts of 20 parts of Myrrhas of 50 parts of Olibanums of Fructus Forsythiae
3 parts of 5 parts of Borneolum Syntheticums of 10 portions of Flos Caryophyllis of Cortex Cinnamomi.
Above-mentioned a kind of dosage form that is used for the health product of mastopathy is a patch.
The adjuvant of the health product that above-mentioned a kind of dosage form that is used for mastopathy is a patch is formed and weight proportion is:
10 parts of 3 parts of Mel of sodium benzoate.
The preparation method that above-mentioned a kind of dosage form that is used for mastopathy is the health product of patch is:
Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli pulverize separately sieving for standby, Radix Angelicae Sinensis, Flos Carthami, Retinervus Luffae Fructus, Fructus Forsythiae, Cortex Cinnamomi adds 8～16 times of water gagings respectively and decocted 1～2.5 hour, filter, the decocting that adds 6～12 times of amounts again boiled 1～2.5 hour, filter, merge filtrate twice, be evaporated to mixture 1～2g/ml, add 70% ethanol and make that to contain the alcohol amount be 70%, left standstill 24 hours, and filtered, decompression recycling ethanol is standby to thick paste, with Mel, Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli fine powder and sodium benzoate add above-mentioned thick paste successively, stir, cool off, the ointment of making is pressed on the special medical medicine plaster carrier makes plaster.
Beneficial effect of the present invention is at the cause of disease and the pathological characters of mastopathy, and clinical employing prevents and treats bonded aggregate measures, and treatment is based on promoting blood circulation to remove obstruction in the collateral, dispersing swelling and dissipating binds, alleviating pain, adopt patch, medicine directly infiltrates skin, and is rapid-action, it is outstanding that effect is, and do not have obvious toxic and side effects.
The specific embodiment
The performance characteristics of raw material among the present invention:
1, Radix Angelicae Sinensis: be the dry root of umbrella section plant Radix Angelicae Sinensis.
Nature and flavor: sweet, hot, warm.
Performance characteristics: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving moistens just unimpeded.Be used for the blood deficiency dull yellowish colored skin, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores.
2, Flos Carthami: be the dried floral of feverfew Flos Carthami.
Nature and flavor: hot, warm.
Performance characteristics: the ware of living stimulates the menstrual flow eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, lochia is not all right, little abdominal mass mass in the abdomen, traumatic injury, skin infection swells and ache.
3, Retinervus Luffae Fructus: be the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae.
Nature and flavor: sweet, little hardship, cold.
Performance characteristics: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens is moisturized laxation.Be used for the cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, constipation.
4, Fructus Forsythiae: be the dry fruit of rhinoceros large bamboo hat with a conical crown and broad brim plant Fructus Forsythiae.
Nature and flavor: bitter, be slightly cold.
Performance characteristics: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Be used for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease, from the beginning of, warm joining the army, the hyperpyrexia excessive thirst, coma is sent out speckle, the pyretic stranguria urine retention.
5, Olibanum: the oleo-gum-resin of oozing out for olive subject plant Ka Shi XIANGSHU and congener trunk skin zone thereof.
Nature and flavor: hot, bitter, warm.
Performance characteristics: promoting blood circulation and stopping pain, detumescence and promoting granulation.Be used for dysmenorrhea, amenorrhea, stomachache with cool feeling, rheumatic arthralgia, traumatic pain and ulcer sore pain, diseases such as acute appendicitis.
6, Myrrha: for the olive subject plant myrrh or belong to the oleo-gum-resin that several plant trunk skin zones ooze out together.
Nature and flavor: bitter, flat.
Performance characteristics: promoting blood circulation and stopping pain, detumescence and promoting granulation.Be used for amenorrhea, dysmenorrhea, stomach abdomen cold type of pain is fallen the button pain of injury, diseases such as ulcer sore pain and acute appendicitis.
7, Cortex Cinnamomi: be the cinnamomic dry bark of canella.
Nature and flavor: hot, sweet, big heat.
Performance characteristics: it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, dizziness due to yang deficiency, the conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
8, Flos Caryophylli: be the alabastrum of dicotyledon Oleaceae plant of clove.
Nature and flavor: hot, warm.
Performance characteristics: warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.Be used for Deficiency and coldness of spleen and stomach, singultus vomiting, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.
9, Borneolum Syntheticum: be water white transparency or the crisp crystallization of white translucent lamellar.
Nature and flavor: hot, bitter, be slightly cold.
Performance characteristics: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Be used for the calentura coma, convulsion is fainted, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
The present invention is made up of Radix Angelicae Sinensis, Flos Carthami, Retinervus Luffae Fructus, Fructus Forsythiae, Olibanum, Myrrha, Cortex Cinnamomi, Flos Caryophylli, Borneolum Syntheticum, the side in Radix Angelicae Sinensis, Flos Carthami promoting blood circulation to restore menstrual flow, pain relieving, be monarch drug; Retinervus Luffae Fructus dispelling wind and removing obstruction in the collateral, promoting blood circulation and stopping pain, the Fructus Forsythiae heat-clearing and toxic substances removing, the diffusing furuncle of detumescence is a ministerial drug; Olibanum, Myrrha promoting blood circulation and stopping pain, detumescence and promoting granulation, Cortex Cinnamomi dispersing cold for relieving pain, invigorating blood circulation analgesia are adjuvant drug; The refreshment of having one's ideas straightened out of Flos Caryophylli reinforcing the kidney and supporting YANG, Borneolum Syntheticum is just medicine.Monarch is played the effect of promoting blood circulation to remove obstruction in the collateral, promoting the circulation of QI to relieve pain altogether.
The present invention identifies to this medicine that through the disease prevention and control center, Shaanxi Province the result shows:
One, character, weight differential, volatile oil are differentiated:
Assay:
1. shape: yellowish-brown unguentum.
2. weight differential :+3.55%.
3. volatile oil is differentiated: be positive reaction.
Two, microbiological indicator
Assay:
| Lot number | 20041026 |
| Total number of bacterial colonies (cfu/g) | ＜10 |
| Mold colony sum (cfu/g) | ＜10 |
| Coliform | Do not detect |
| Bacillus pyocyaneus | Do not detect |
| Staphylococcus aureus | Do not detect |
Estimate: according to DB61-266-1998 " health product hygienic requirements ", institute's sample product are up to specification.
Three, rat acute percutaneous toxicity test
1, tried thing: the present invention's " mammary gland subsides ".
2, experimental animal: 20 of SD rat, male and female half and half, body weight 180-220g, one-level animal (the moving word of doctor 08-005 number) is proposed by Xian Medical Univ's Experimental Animal Center.
3, animal housing's environment: temperature: 24-27 ℃, relative humidity: 60 ± 5%.
4, test method: tested preceding 24 hours, its back wool is sloughed, the depilation scope is 10% of a body surface area, dosage (with an amount of vaseline furnishing ointment) by 0.5g/100g applies and fixes examination Mus depilation position, after 24 hours, warm water is removed the residual thing that tried, and observes continuously 7 days.
5, result of the test: do not see examination Mus whole body ANOMALOUS VARIATIONS in the observation period, do not see the phenomena of mortality yet, be coated with tried the thing part not show swell, fester, reaction such as inflammation necrosis, the results are shown in Table.
| The animal sex | Dosage (mg/kg) | Examination Mus number (only) | Dead animal number (only) | Mortality rate (%) |
| Female Mus | 5000 | 10 | 0 | 0 |
| Male Mus | 5000 | 10 | 0 | 0 |
Last table expression, the present invention's " mammary gland subsides " is to female rat acute dermal toxicity LD
50All greater than 5000mg/kg.
6, evaluation of result: according to acute dermal toxicity grade scale among the DB61-267-1998 " health product peace sage's property toxicological evaluation program and shuttle proved recipe method ", the nontoxic level in the present invention's " mammary gland subsides " true border of rat toxicity percutaneous toxicity.
Four, skin irritation test
1, tried thing: the present invention's " mammary gland subsides ", yellowish-brown patch.
2, experimental animal: 4 of Japan large ear rabbits, body weight 2.5 ± 0.5kg, one-level animal (the moving word of doctor 08-018 number) is proposed by Xian Medical Univ's Experimental Animal Center.
3, animal environment: temperature: 24-27 ℃, relative humidity: 60 ± 5%.
4, test method: will be tried each unhairing 3cm * 6cm of rabbit back spinal column both sides in preceding 24 hours to trying thing, and get and only tried thing 0.5g/, and add an amount of vaseline furnishing ointment, and evenly be coated in a side unhairing place, opposite side is coated with distilled water as blank.Remove the residual thing that tried with warm water after 4 hours, observe 1,24,48,72 hour local skin response situation.
Mammary gland pastes skin irritation reaction appraisal result
6, evaluation of result: according to skin irritation strength grading standard among the DB61-267-1998 " the health product safety toxicological evaluation program and the method for inspection ", the present invention's " mammary gland subsides " belongs to nonirritant to skin irritation intensity.
Five, skin anaphylactic test
1, tried thing: the present invention's " mammary gland subsides " is the yellowish-brown unguentum.Positive control: 2,4-dinitro-chloro-benzene (DNCB), chemical reagent factory in Beijing produces.
2, laboratory animal: 30 of Britain Cavia porcelluss, male and female half and half, body weight 250-300g is provided by The Fourth Military Medical University experimental animal center.
3, animal environment: temperature: 24-27 ℃, relative humidity: 60 ± 5%.
4, test method: Give is tried preceding 24 hours of thing guinea pig back spinal column diamond wool is taken off the about 3cm * 3cm of the every side of unhairing scope.To test Cavia porcellus and be divided into three groups at random by body weight, sex, 10 every group, female, hero half and half is respectively and is tried thing group, negative control group and positive controls.
Sensitization contact; Get and tried thing 0.2g, evenly be coated in depilation district, back, animal left side, continue 6 hours.The 7th day and fortnight are used with quadrat method and are repeated once, and positive controls is coated with 1%DNCB, and negative control group does not deal with.
Excite contact: to fortnight after being tried thing, will be tried thing 0.2g in last, and evenly be coated on depilation district, guinea pig back right side, and remove after 6 hours and tried thing, and observe the anaphylaxis situation at once, and observe again in 1,24,48,72 hour then.Positive controls is coated with 0.1%DNCB, and negative control group does not deal with.Observational technique is with being tried the thing group.The result estimates by relevant sensitization of skin standard among the DB61-267-1998 " the health product safety toxicological evaluation program and the method for inspection ".
| Group | Number of animals | The sensitization number | The sensitization rate | Intensity |
| Tried thing | 10 | 0 | 0 | No sensitization |
| Negative control | 10 | 0 | 0 | No sensitization |
| Positive control | 10 | 10 | 100 | The extreme sensitization |
Observed result: being tried thing group sensitization rate is 0.
5, evaluation of result: according to relevant sensitization of skin standard among the DB61-267-1998 " the health product safety toxicological evaluation program and the method for inspection ", the present invention's " mammary gland subsides " belongs to no sensitization.
Six, antiinflammatory test, analgesic test, microcirculation test
1, assay:
(1), antiinflammatory test: the test of the present invention's " mammary gland subsides " mouse corrosion disease, test group and matched group relatively have significant difference, illustrate that mammary gland posts the effect that anti-dimethylbenzene causes the auricular concha inflammation.
(2), analgesic test: mice analgesic test (writhing method), relatively there were significant differences for test group and matched group, illustrates that mammary gland posts analgesic activity.
(3), microcirculation test: what be subjected to examination group Mice Auricle fine motion vein bore and capillary vessel number and matched group relatively has a significant difference, illustrates that mammary gland posts the effect of microcirculation improvement.
2, estimate: the present invention's " mammary gland subsides " has the effect of antiinflammatory, analgesia and microcirculation improvement.
Embodiment 1:
Chinese medicine of the present invention is made by following materials of weight proportions:
50 parts of 100 parts of Retinervus Luffae Fructuss of 100 parts of Flos Carthamis of Radix Angelicae Sinensis
20 parts of 20 parts of Myrrhas of 50 parts of Olibanums of Fructus Forsythiae
3 parts of 5 parts of Borneolum Syntheticums of 10 portions of Flos Caryophyllis of Cortex Cinnamomi.
Dosage form of the present invention is that the preparation method processing step of patch is as follows:
Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli pulverize separately sieving for standby, Radix Angelicae Sinensis, Flos Carthami, Retinervus Luffae Fructus, Fructus Forsythiae, Cortex Cinnamomi adds 8～16 times of water gagings respectively and decocted 1～2.5 hour, filter, the decocting that adds 6～12 times of amounts again boiled 1～2.5 hour, filter, merge filtrate twice, be evaporated to mixture 1～2g/ml, add 70% ethanol and make that to contain the alcohol amount be 70%, left standstill 24 hours, and filtered, decompression recycling ethanol is standby to thick paste, with Mel, Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli fine powder and sodium benzoate add thick paste successively, stir, cool off, the ointment of making is pressed on the special medical medicine plaster carrier makes plaster.
Embodiment 2:
Chinese medicine of the present invention is made by following materials of weight proportions:
40 parts of 90 parts of Retinervus Luffae Fructuss of 90 parts of Flos Carthamis of Radix Angelicae Sinensis
10 parts of 10 parts of Myrrhas of 40 parts of Olibanums of Fructus Forsythiae
1 part of 3 parts of Borneolum Syntheticum of 5 portions of Flos Caryophyllis of Cortex Cinnamomi.
Dosage form of the present invention is that the preparation method processing step of patch is the same.
Embodiment 3:
Chinese medicine of the present invention is made by following materials of weight proportions:
60 parts of 110 parts of Retinervus Luffae Fructuss of 110 parts of Flos Carthamis of Radix Angelicae Sinensis
30 parts of 30 parts of Myrrhas of 60 parts of Olibanums of Fructus Forsythiae
5 parts of 8 parts of Borneolum Syntheticums of 15 portions of Flos Caryophyllis of Cortex Cinnamomi.
Dosage form of the present invention is that the preparation method processing step of patch is the same.
Claims (5)
1, a kind of health product that are used for mastopathy is characterized in that: the raw materials of effective components of described health product is formed and weight proportion is:
40～60 parts of 90～110 parts of Retinervus Luffae Fructuss of 90～110 parts of Flos Carthamis of Radix Angelicae Sinensis
10～30 parts of 10～30 parts of Myrrhas of 40～60 parts of Olibanums of Fructus Forsythiae
1～5 part of 3～8 parts of Borneolum Syntheticum of 5～15 portions of Flos Caryophyllis of Cortex Cinnamomi.
2, a kind of health product that are used for mastopathy according to claim 1 is characterized in that: the raw materials of effective components of described health product is formed and weight proportion is:
50 parts of 100 parts of Retinervus Luffae Fructuss of 100 parts of Flos Carthamis of Radix Angelicae Sinensis
20 parts of 20 parts of Myrrhas of 50 parts of Olibanums of Fructus Forsythiae
3 parts of 5 parts of Borneolum Syntheticums of 10 portions of Flos Caryophyllis of Cortex Cinnamomi.
3, a kind of health product that are used for mastopathy according to claim 1 and 2, it is characterized in that: described dosage form is a patch.
4, a kind of health product that are used for mastopathy according to claim 3 is characterized in that: described dosage form is that the adjuvant of patch is formed and weight proportion is:
10 parts of 3 parts of Mel of sodium benzoate.
5, a kind of health product that are used for mastopathy according to claim 3 and preparation method thereof is characterized in that: described dosage form is that the preparation method of patch is:
Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli pulverize separately sieving for standby, Radix Angelicae Sinensis, Flos Carthami, Retinervus Luffae Fructus, Fructus Forsythiae, Cortex Cinnamomi adds 8～16 times of water gagings respectively and decocted 1～2.5 hour, filter, the decocting that adds 6～12 times of amounts again boiled 1～2.5 hour, filter, merge filtrate twice, be evaporated to mixture 1～2g/ml, add 70% ethanol and make that to contain the alcohol amount be 70%, left standstill 24 hours, and filtered, decompression recycling ethanol is standby to thick paste, with Mel, Olibanum, Myrrha, Borneolum Syntheticum, Flos Caryophylli fine powder and sodium benzoate add above-mentioned thick paste successively, stir, cool off, the ointment of making is pressed on the special medical medicine plaster carrier makes plaster.
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| CNA2009100223367A CN101601729A (en) | 2009-05-05 | 2009-05-05 | A kind of health product that is used for mastopathy and preparation method thereof |
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| CNA2009100223367A CN101601729A (en) | 2009-05-05 | 2009-05-05 | A kind of health product that is used for mastopathy and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105380982A (en) * | 2015-11-17 | 2016-03-09 | 刘国灿 | Traditional Chinese medicine composition for treating breast diseases and preparation method thereof |
| CN111228385A (en) * | 2020-03-06 | 2020-06-05 | 昆山聚康堂中医门诊部有限公司 | Mammary gland health-care patch and preparation method thereof |
-
2009
- 2009-05-05 CN CNA2009100223367A patent/CN101601729A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105380982A (en) * | 2015-11-17 | 2016-03-09 | 刘国灿 | Traditional Chinese medicine composition for treating breast diseases and preparation method thereof |
| CN111228385A (en) * | 2020-03-06 | 2020-06-05 | 昆山聚康堂中医门诊部有限公司 | Mammary gland health-care patch and preparation method thereof |
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Open date: 20091216 |