CN101569704A - Traditional Chinese medicine for adjuvant therapy of hypnotic poisoning - Google Patents
Traditional Chinese medicine for adjuvant therapy of hypnotic poisoning Download PDFInfo
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- CN101569704A CN101569704A CNA2008100949923A CN200810094992A CN101569704A CN 101569704 A CN101569704 A CN 101569704A CN A2008100949923 A CNA2008100949923 A CN A2008100949923A CN 200810094992 A CN200810094992 A CN 200810094992A CN 101569704 A CN101569704 A CN 101569704A
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Abstract
The invention relates to a traditional Chinese medicine for the adjuvant therapy of hypnotic poisoning. The invention develops a pure traditional Chinese medicine compound preparation according to the Chinese medicine theory, the experience of the medical circle, the clinical experience of the inventor and the modern pharmacological knowledge of the traditional Chinese medicine. The invention mainly aims at the therapy of a patient suffering from hypnotic poisoning by the alimentary canal, and eliminates a weak link of the residual toxin of the intestinal canal. By the clinical application of many years, the traditional Chinese medicine obtains a better therapy effect. The traditional Chinese medicine is characterized by the effects of strong cathartic function, toxin adsorption, toxin expelling, detoxification and emiction assistance. The traditional Chinese medicine is better than other cathartic methods adopted clinically, and has a leading superiority in the technique. The formula of the traditional Chinese medicine comprises rhubarb, talcum, raw rhizome of cyrtomium, aloe, tea leaves, senna, raw liquorice, raw mung bean, and the like. The invention is compound decocted decoction with professional production in a bottling mode, and every bottle contains 250 milliliters. After gastric lavage, a patient suffering from hypnotic poisoning orally takes the compound decocted decoction or is infused with the compound decocted decoction of 250-1000 milliliters every time according to an illness condition.
Description
Technical field
The Chinese medicine that adjuvant therapy of hypnotic is poisoned
Technical background
Because the extensive use of sleeping pill (hypnotic, tranquilizer) makes it to become the modal poisonous substance of poisoning through digestive tract of town dweller.Tool statistics, poisoning with hypnotic account for 1.31% of all outpatient service emergency treatment diseases
[1]Account for 31% of all poisoning class diseases
[2]Account for 73.17% of drug intoxication
[3]Add up my 3 years (1998～2000 years) cases of emergency department of institute, find that such poisoning accounts for 83% of all drug intoxication.So its hazardness is very big.Therapeutic Method mainly is application of special effects antidote, emetic, gastric lavage, catharsis and suits the medicine to the illness.The method that at present both at home and abroad conventional removing enters the gastrointestinal tract poisonous substance is emetic, gastric lavage and catharsis.Though the poisoning back through repeatable gastrolavage, is still adhered on the gastrointestinal mucosa gauffer, remaining a lot of poisonous substances, people's intestinal tube has about 7 meters long, and residual quantity is very big sometimes, as untimely removing, will continue to be absorbed into blood, causes the state of an illness to increase the weight of, and increases mortality rate.Thus, catharsis is to remove the very important ring of residual poisonous substance.But in clinical position, often have the heavily tendency of the light catharsis of gastric lavage, the present also method of neither one catharsis preferably clinically, especially tcm field also the effective preparation of neither one to it.
At present the method for catharsis mainly is to use Chinese medicine or Western medicine in the hospital, for example: 1. magnesium sulfate, sodium sulfate, mannitol: increase enteral osmotic pressure, height oozes catharsis; 2. phenolphthalein: zest catharsis; 3. glycerol, sorbitol etc.: permeability, slight zest catharsis; 4. Chinese medicine DACHENGQI TANG; 5. single medicinal material Radix Et Rhizoma Rhei, Folium Sennae etc.; 6. aloe capsule etc. is a laxative.Overall merit is as follows: 1, curative effect is not high, the curative effect height that has but side effect is big; 2, do not possess absorption poisonous substance, functions of expelling toxin; 3, do not possess non-special function of detoxification; 4, the function of no tonneau urine.For example, magnesium sulfate: coma patient should not be used limitation with event; Curative effects such as sodium sulfate, mannitol, glycerol are low; Chinese medicine DACHENGQI TANG in situ preparation has little time; Single medicinal material Radix Et Rhizoma Rhei, Folium Sennae etc. are too swift and fierce again, and the bad grasp of dose-effect has been used many and can have been caused this medicine to poison; Phenolphthalein and other laxatives etc. are not suitable for the emergency call salving of acute poisoning.
At above-mentioned situation, be sought after a kind of above-mentioned shortcoming that overcome clinically, not only efficiently but also conveniently use, few side effects, possess the Chinese medicine preparation of dispelling toxicity, detoxicating, tonneau urine simultaneously.
Annotate: [1] Li Jiguang etc." research of the Northeast's emergency treatment spectrum of disease " the emergency medicine fifth phase in 1997 [2] Yang Zhenfa etc." acute poisoning 182 examples are analyzed " the academic meeting of national emergency treatment collection of thesis [3] Li Huande in 1999 etc." clinical meaning of therapeutic drug monitoring in salvage drug toxonosis people " Chinese emergency medicine fifth phase inside front cover in 1992
Summary of the invention
The present invention is the Chinese medicine that a kind of adjuvant therapy of hypnotic is poisoned
When being mainly used in the acute poisoning with hypnotic patient of clinical rescue, remove this important step of the residual poisonous substance of gastrointestinal tract.Dosage form is the compound recipe pure Chinese medicinal preparation, is aqueous solution (decocting decoction), and professional processing and preparing, aseptic bottled, 250 milliliters/bottle.Its composition is the legal Chinese medicine of national Chinese medicine pharmacopeia approval.The present invention according to the Chinese medicine and pharmacy theory, sum up forefathers and my clinical experience, gain knowledge in conjunction with the Chinese medicine modern pharmacology, and through research, clinical experiment gained repeatedly.
In the present invention prescription, mainly adopted: 1. 2. Folium Sennae of Radix Et Rhizoma Rhei: contain anthraquinone component, can stimulate colon to advance the property wriggling; Its tool bitter cold of theory of Chinese medical science has effects such as rushing down heat clearing away down, detoxifcation, blood circulation promoting and blood stasis dispelling, stronger purging heat to relax the bowels, relaxing the bowels with lubricant drugs softening the hard mass is arranged, cleanse gastrointestinal effect.3. give birth to 4. 5. Folium Camelliae sinensis of Aloe of Rhizoma Osmundae: non-specific Detoxication is arranged; 6. Talcum: adsorbable intestinal poison, diuresis with toxin expelling, set upright the poison of dispelling.7. the 8. living Semen phaseoli radiati of Radix Glycyrrhizae: turn round and look at and protect gastric qi, Fuzheng Jiedu.All medicines share in order to absorption poisonous substance, toxin expelling, detoxify, set upright the poison of dispelling, tonneau two just.
The present invention severe hypnotic tranquilizers poisoning patient's in 90 examples clinical studies show: add with the doctor trained in Western medicine conventional treatment and to use auxiliary treatment of the present invention, treatment group obvious effective rate is 68.3%; Total effective rate is 91.7%.The matched group obvious effective rate is 51.7%; Total effective rate is 70.9%.Both relatively have significant difference (P＜0.05).Treatment group and matched group are relatively gone up in reduction blood drug level, the short indexs such as time, defecation time and number of times of waking up, and significant difference (P＜0.05) is all arranged.Zoopery confirms that also the present invention all has remarkable positive impact to white mice gastric emptying, white mice intestinal propulsion rate, rabbit isolated smooth muscle etc.Also measure and turn out to be the very wide medicine of safety range through LD50.
Its main feature is: 1. the catharsis effect is strong, and absorption poisonous substance, detoxicating, toxin expelling effect are powerful and reliable; 2. has non-specific function of detoxification; 3. tonneau urine function; 4. pure compound Chinese medicinal preparation, no ill effect; 5. bottling liquid is used conveniently.Its finished product is brown than concentrated solution, the 250ml/ bottle; Usage: patient's gastric lavage does not wait (looking state of an illness weight and patient reaction) after stomach tube pours into (clear-headed can be oral) each consumption 250 ~ 1000ml.Can every day twice ~ ~ three times.
Shortcoming: unsuitable stored for a long time, unstable properties, curative effect reduces.Three months time limits guaranteed the quality.(the present invention obtains Yantai City's progress prize in scientific and collective technology third prize in 2002.Certificate number: 2002-3-41a-1)
The specific embodiment
Recipe ingredient of the present invention and content embodiment:
Prescription and consumption are: Radix Et Rhizoma Rhei 25 grams; Talcum 30 grams; Give birth to Rhizoma Osmundae 30 grams; Aloe 5 grams; Folium Camelliae sinensis 30 grams; Folium Sennae 5 grams; Radix Glycyrrhizae 30 grams; Living Semen phaseoli radiati 30 grams.
Claims (1)
- A kind of Chinese medicine preparation is characterized in that: prescription and consumption are: Radix Et Rhizoma Rhei 25 grams; Talcum 30 grams; Give birth to Rhizoma Osmundae 30 grams; Aloe 5 grams; Folium Camelliae sinensis 30 grams; Folium Sennae 5 grams; Radix Glycyrrhizae 30 grams; Living Semen phaseoli radiati 30 grams.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100949923A CN101569704A (en) | 2008-04-30 | 2008-04-30 | Traditional Chinese medicine for adjuvant therapy of hypnotic poisoning |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100949923A CN101569704A (en) | 2008-04-30 | 2008-04-30 | Traditional Chinese medicine for adjuvant therapy of hypnotic poisoning |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101569704A true CN101569704A (en) | 2009-11-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008100949923A Pending CN101569704A (en) | 2008-04-30 | 2008-04-30 | Traditional Chinese medicine for adjuvant therapy of hypnotic poisoning |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860933A (en) * | 2014-03-13 | 2014-06-18 | 杨芳 | Traditional Chinese medicine for treating endosulfan toxication |
-
2008
- 2008-04-30 CN CNA2008100949923A patent/CN101569704A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860933A (en) * | 2014-03-13 | 2014-06-18 | 杨芳 | Traditional Chinese medicine for treating endosulfan toxication |
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| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Cao Maiyuan Document name: Notification of before Expiration of Request of Examination as to Substance |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091104 |