CN101559176B - Chinese materia medica preparation for lowering blood pressure - Google Patents
Chinese materia medica preparation for lowering blood pressure Download PDFInfo
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- CN101559176B CN101559176B CN200910015166XA CN200910015166A CN101559176B CN 101559176 B CN101559176 B CN 101559176B CN 200910015166X A CN200910015166X A CN 200910015166XA CN 200910015166 A CN200910015166 A CN 200910015166A CN 101559176 B CN101559176 B CN 101559176B
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Abstract
The present invention relates to a Chinese materia medica preparation for lowering blood pressure, which is prepared by the bulk drugs with weight as follows: 25-35g of rhizoma gastrodiae, 50-70g of uncaria, 80-100g of crude cassia seeds, 90-110g of caulis polygoni multiflori, 80-100g of motherwort, 80-100g of Chinese taxillus twig, 55-65g of radix scutellariae, 50-70g of radix cyathulae, 50-70g of angelica, 50-70g of peach seeds, 35-45g of safflower, 25-35g of figwort, 50-70g of white paeony root, 80-100g of dried rhizome of rehmannia, 50-70g of raw oysters, 50-70g of shizandra, 25-35g of fructus gardeniae, 80-100g of cortex lycii radicis and 50-70g of seabuckthorn. The Chinese materia medica preparation has the beneficial effects of scientific compatibility of drugs, high effective rate, rapid effect, low recurrence rate, no obvious toxic side effect, simple preparing process and lower production cost.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of blood pressure lowering, belong to technical field of Chinese medicines.
Background technology
Hypertension is a kind of long-term chronic disease of progress gradually, often changes with organ dysfunction such as heart and brain, kidney or device matter, and as can not in time treating, its complication is many can to make the people disable or cause death.This disease can be by due to the pathogenesis of multiple pathogenic factors and complexity, and heredity is secreted in the central nervous system function imbalance in the body fluid, and the dysfunction of kidney cerebrovascular pressure receptor etc. all can cause hypertension.
At present, though the antihypertensive drug kind of clinical use is more, effect is relatively poor during owing to single drug, and side effect is more, generally adopts the several drugs use in conjunction, and need take medicine throughout one's life, brings a lot of inconvenience for patient's life.
Therefore, people are still at research and development antihypertensive drug more safe and effective, easy to use.
Summary of the invention
Be to solve the deficiencies in the prior art, the present invention aims to provide a kind of Chinese medicine preparation of evident in efficacy, rapid, blood pressure lowering that side effect is little.
The present invention is achieved by the following technical solutions:
The Chinese medicine preparation of described blood pressure lowering is to be made by following bulk drugs: Rhizoma Gastrodiae 25-35g Ramulus Uncariae Cum Uncis 50-70g gives birth to Semen Cassiae 80-100g Caulis Polygoni Multiflori 90-110g Herba Leonuri 80-100g Herba Taxilli 80-100g Radix Scutellariae 55-65g Radix Cyathulae 50-70g Radix Angelicae Sinensis 50-70g Semen Persicae 50-70g Flos Carthami 35-45g Radix Scrophulariae 25-35g Radix Paeoniae Alba 50-70g Radix Rehmanniae 80-100g Concha Ostreae 50-70g Fructus Schisandrae Chinensis 50-70g SHANZHIZI 25-35g Cortex Lycii 80-100g Fructus Hippophae 50-70g.
The Chinese medicine preparation of above-mentioned blood pressure lowering, preferably made by following bulk drugs: Rhizoma Gastrodiae 30g Ramulus Uncariae Cum Uncis 60g gives birth to Semen Cassiae 90g Caulis Polygoni Multiflori 100g Herba Leonuri 90g Herba Taxilli 90g Radix Scutellariae 60g Radix Cyathulae 60g Radix Angelicae Sinensis 60g Semen Persicae 60g Flos Carthami 40g Radix Scrophulariae 30g Radix Paeoniae Alba 60g Radix Rehmanniae 90g Concha Ostreae 60g Fructus Schisandrae Chinensis 60g SHANZHIZI 30g Cortex Lycii 90g Fructus Hippophae 60g.
The material medicine crushed after being dried of above-mentioned recipe quantity is become fine powder, cross 100～120 mesh sieves, with water pill, drying promptly gets Chinese medicine preparation of the present invention, can make a kind of dosage form on the pharmaceutics as required.
The traditional Chinese medical science thinks that hypertension incidence and physical factors, feelings will factor and life imbalance etc. have confidential relation, patient mostly to be the Liver and kidney imbalance of YIN and YANG, and hyperactivity of YANG due to deficiency of YIN, phlegm-damp blood stasis are detained, and taste are subjected to G, heart-fire Yi Sheng etc.
The present invention selects Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis for use, gives birth to Semen Cassiae, Concha Ostreae, Caulis Polygoni Multiflori, Herba Taxilli with suppressing the hyperactive liver to relieve the wind syndrome, wind-expelling pain-stopping, tranquilizing by nourishing the heart; Herba Leonuri, Flos Carthami, Semen Persicae, Radix Cyathulae be with promoting blood flow to regulate menstruation, easing joint movement, inducing diuresis to remove edema; Radix Scutellariae, Radix Scrophulariae, the Radix Rehmanniae, SHANZHIZI be with clearing away heat and cooling blood, eliminating fire and detoxication; Be aided with the Radix Paeoniae Alba and have the yin fluid astringing that nourishes blood concurrently, the effect of suppressing liver-YANG, the Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; Cortex Lycii has removing heat from blood and removes steaming, the effect of lung heat clearing pathogenic fire reducing; Fructus Hippophae has eliminating phlegm and stopping cough, relieving dyspepsia, the effect of promoting blood circulation to remove blood stasis.
Medicine of the present invention based on suppressing the hyperactive liver and subsiding YANG, nourishing the liver and kidney, eliminate the phlegm and invigorate blood circulation, and have the effect of vessel softening, enhancing human body immunity power, be mainly used in essential hypertension, the headache that excessive rising of liver-YANG is caused, dizziness, tinnitus, cardiopalmus, insomnia etc. have good effect.
The invention has the beneficial effects as follows: the compatibility science, the effective percentage height, rapid-action, relapse rate is low, no obvious toxic-side effects, preparation technology is simple, and production cost is lower.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment.
Embodiment 1
The Chinese medicine preparation of described blood pressure lowering is to be made by following bulk drugs: Rhizoma Gastrodiae 30g Ramulus Uncariae Cum Uncis 60g gives birth to Semen Cassiae 90g Caulis Polygoni Multiflori 100g Herba Leonuri 90g Herba Taxilli 90g Radix Scutellariae 60g Radix Cyathulae 60g Radix Angelicae Sinensis 60g Semen Persicae 60g Flos Carthami 40g Radix Scrophulariae 30g Radix Paeoniae Alba 60g Radix Rehmanniae 90g Concha Ostreae 60g Fructus Schisandrae Chinensis 60g SHANZHIZI 30g Cortex Lycii 90g Fructus Hippophae 60g.
The material medicine crushed after being dried of above-mentioned recipe quantity is become fine powder, cross 100～120 mesh sieves, with water pill, drying promptly gets the sepia watered pill.
Oral, one time 6 gram, 3 times on the one, warm water takes.Period in a medicine diet compatibility and incompatibility of drugs raw food, vinegar-pepper food.
Embodiment 2
The Chinese medicine preparation of described blood pressure lowering is to be made by following bulk drugs: Rhizoma Gastrodiae 35g Ramulus Uncariae Cum Uncis 50g gives birth to Semen Cassiae 100g Caulis Polygoni Multiflori 90g Herba Leonuri 100g Herba Taxilli 100g Radix Scutellariae 65g Radix Cyathulae 70g Radix Angelicae Sinensis 70g Semen Persicae 70g Flos Carthami 35g Radix Scrophulariae 25g Radix Paeoniae Alba 50g Radix Rehmanniae 80g Concha Ostreae 70g Fructus Schisandrae Chinensis 50g SHANZHIZI 35g Cortex Lycii 80g Fructus Hippophae 50g.Preparation method, usage and dosage are with embodiment 1.
Embodiment 3
The Chinese medicine preparation of described blood pressure lowering is to be made by following bulk drugs: Rhizoma Gastrodiae 25g Ramulus Uncariae Cum Uncis 70g gives birth to Semen Cassiae 80g Caulis Polygoni Multiflori 110g Herba Leonuri 80g Herba Taxilli 80g Radix Scutellariae 55g Radix Cyathulae 50g Radix Angelicae Sinensis 50g Semen Persicae 50g Flos Carthami 45g Radix Scrophulariae 35g Radix Paeoniae Alba 70g Radix Rehmanniae 100g Concha Ostreae 50g Fructus Schisandrae Chinensis 70g SHANZHIZI 25g Cortex Lycii 100g Fructus Hippophae 70g.Preparation method, usage and dosage are with embodiment 1.
Clinical experiment is observed
(1) physical data
Choose hyperpietic's 187 examples of hospitalization during in February, 2007 to the 2008 year December, male's 133 examples wherein, women's 54 examples, 43～72 years old age; The course of disease is half a year to 10 year.1 phase hyperpietic, 139 examples wherein, 2 phase hyperpietics, 44 examples, 3 phase hyperpietics, 4 examples.
The patient is divided into treatment group and matched group at random, and the grouping situation sees the following form.
| Patient's number | Mean age | Ill situation | |
| Matched group | Man's 63 examples, women 25 examples | 57.1 year | 1 phase patient, 70 examples, 2 phase patients, 20 examples, 3 phase patients, 3 examples |
| The treatment group | Man's 70 examples, women 29 examples | 58.4 year | 1 phase patient, 69 examples, 2 phase patients, 24 examples, 3 phase patients, 1 example |
(2) Therapeutic Method
The treatment group: give the medicine of the embodiment of the invention 1, every day 3 times, each 6g, 7 days is 1 course of treatment, treats 5～7 courses of treatment altogether.
Matched group: take conventional Western medicine and carry out blood pressure lowering.
Period in a medicine diet compatibility and incompatibility of drugs raw food, vinegar-pepper food.
(3) therapeutic evaluation standard
Cure: clinical symptoms all disappears, high pressure≤120-140 mercury column, and low pressure≤80-90 mercury column, drug withdrawal blood pressure does not after two months rebound;
Effectively: clinical symptoms disappears substantially, high pressure≤120-140 mercury column, and low pressure≤80-90 mercury column, drug withdrawal blood pressure after two months has a rebound;
Invalid: and compare before the treatment, each physics and chemistry detects index no change or sx.
(4) therapeutic effect sees the following form.
| Cure number | Significant figure | Total effective rate | |
| Matched group | 4 | 61 | 73.7％ |
| The treatment group | 18 | 59 | 86.5％ |
Safety indexes to treatment group patient detects, and does not find liver, kidney, core function abnormality, and hematuria is just checked and also met conventional criteria.
Claims (2)
1. the Chinese medicine preparation of a blood pressure lowering is characterized in that it being to be made by following bulk drugs: the living Semen Cassiae 80-100g of Rhizoma Gastrodiae 25-35g Ramulus Uncariae Cum Uncis 50-70g Caulis Polygoni Multiflori 90-110g Herba Leonuri 80-100g Herba Taxilli 80-100g Radix Scutellariae 55-65g Radix Cyathulae 50-70g Radix Angelicae Sinensis 50-70g Semen Persicae 50-70g Flos Carthami 35-45g Radix Scrophulariae 25-35g Radix Paeoniae Alba 50-70g Radix Rehmanniae 80-100g Concha Ostreae 50-70g Fructus Schisandrae Chinensis 50-70g SHANZHIZI 25-35g Cortex Lycii 80-100g Fructus Hippophae 50-70g.
2. the Chinese medicine preparation of blood pressure lowering according to claim 1 is characterized in that it being to be made by following bulk drugs: the living Semen Cassiae 90g of Rhizoma Gastrodiae 30g Ramulus Uncariae Cum Uncis 60g Caulis Polygoni Multiflori 100g Herba Leonuri 90g Herba Taxilli 90g Radix Scutellariae 60g Radix Cyathulae 60g Radix Angelicae Sinensis 60g Semen Persicae 60g Flos Carthami 40g Radix Scrophulariae 30g Radix Paeoniae Alba 60g Radix Rehmanniae 90g Concha Ostreae 60g Fructus Schisandrae Chinensis 60g SHANZHIZI 30g Cortex Lycii 90g Fructus Hippophae 60g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910015166XA CN101559176B (en) | 2009-05-19 | 2009-05-19 | Chinese materia medica preparation for lowering blood pressure |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910015166XA CN101559176B (en) | 2009-05-19 | 2009-05-19 | Chinese materia medica preparation for lowering blood pressure |
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| CN101559176A CN101559176A (en) | 2009-10-21 |
| CN101559176B true CN101559176B (en) | 2011-09-07 |
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| CN200910015166XA Expired - Fee Related CN101559176B (en) | 2009-05-19 | 2009-05-19 | Chinese materia medica preparation for lowering blood pressure |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101401910A (en) * | 2008-09-23 | 2009-04-08 | 罗先德 | Medicament for treating hypertension |
| CN101406672B (en) * | 2008-11-16 | 2011-05-04 | 路敦祥 | Chinese medicinal liquor for treating hypertension |
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- 2009-05-19 CN CN200910015166XA patent/CN101559176B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101401910A (en) * | 2008-09-23 | 2009-04-08 | 罗先德 | Medicament for treating hypertension |
| CN101406672B (en) * | 2008-11-16 | 2011-05-04 | 路敦祥 | Chinese medicinal liquor for treating hypertension |
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| CN101559176A (en) | 2009-10-21 |
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Granted publication date: 20110907 Termination date: 20120519 |