CN101554425B - Drug for curing chronic bronchitis - Google Patents
Drug for curing chronic bronchitis Download PDFInfo
- Publication number
- CN101554425B CN101554425B CN2009100154189A CN200910015418A CN101554425B CN 101554425 B CN101554425 B CN 101554425B CN 2009100154189 A CN2009100154189 A CN 2009100154189A CN 200910015418 A CN200910015418 A CN 200910015418A CN 101554425 B CN101554425 B CN 101554425B
- Authority
- CN
- China
- Prior art keywords
- drug
- chronic bronchitis
- treatment
- effect
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of traditional Chinese medicine, in particular to a drug for curing chronic bronchitis. The drug is mainly prepared from the following raw materials according two weight proportions: 100-120 g of fructus nandinae, 150-200 g of gall powder, 100-120 g of ordate houttuynia, 100-120 g of dried orange peel, 150-200 g of gnetum parvifolium, 150-200 g of pyrrosia linguaand 150-200 g of thorny elaeagnus leaf. The drug has the advantages of reliable curing effect and fast effect and has the functions of desensitizing and adjusting vegetative nerve disorder, directly expanding the smooth muscle of the trachea, relieving the convulsion of the smooth muscle of the trachea, reducing epithelia of subcutaneous nodules and neutrophil cells, relieving cytopathy and obviously weakening the violence of pathogenic bacteria.
Description
Technical field:
The present invention relates to the field of Chinese medicines, especially a kind of medicine for the treatment of chronic bronchitis.
Background technology:
Chronic bronchitis is a kind of obstinate frequently-occurring disease, and patient is in the majority with the old people.Common sympton based on cough, excessive phlegm, pant, in case ill, the course of disease is longer, often repeatedly, susceptible disease more when particularly autumn, winter, spring, exchanged season, it is difficult to cure.The bronchitic medicine of existing treatment is a lot, but therapeutic effect is all undesirable, and recurrence easily.
Summary of the invention:
The invention provides a kind of medicine for the treatment of chronic bronchitis, its curative effect is reliable, and instant effect has solved problems of the prior art.
The present invention solves the problems of the technologies described above the technical scheme that is adopted to be: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 100～120g by following raw materials by weight proportions, gallbladder powder 150～200g, Herba Houttuyniae 100～120g, Pericarpium Citri Reticulatae 100～120g, Caulis Gneti Parvifolii 150～200g, Folium Pyrrosiae 150～200g, Folium Elaeagni 150～200g.
Preparation of the present invention and instructions of taking are as follows: take by weighing Fructus Nandinae Domesticae, gallbladder powder, Pericarpium Citri Reticulatae, Herba Houttuyniae by weight ratio and cross 400 mesh sieves to make medicated powder standby; Take by weighing Caulis Gneti Parvifolii, Folium Pyrrosiae, Folium Elaeagni again and cross 60 mesh sieves, these three kinds of raw materials are added decocting filter half an hour, connect and fry in shallow oil three times, it is standby that three filtrate is condensed into scattered paste shape; Be placed on drying baker inner drying, sterilization after medicated powder and mass stirred, incapsulate then and get final product.This medicine is taken 3 times every day, and each 4, one after each meal also can be according to conditions of patients proper transformation dose.
Above-mentioned each crude drug effect is as follows:
Fructus Nandinae Domesticae: bitter in the mouth, property is flat, and is slightly poisonous, relieving cough and asthma.It is about 0.085% that Fructus Nandinae Domesticae contains oxygen-methyl-nandina alkali, different corydine and protopine.
Gallbladder powder: bitter in the mouth.Cold in nature.Heat-clearing and toxic substances removing, Li Wen, cough-relieving relieving constipation.Gallbladder powder contains cholate 10～15%, and the sodium salt of main cholic acid and glycocholic acid contains bilirubin, biliverdin and lecithin in addition, and contains a small amount of cholesterol, choline, fat and carbamide.Sodium cholate has the maincenter antitussive effect, and sodium cholate has the effect of expansion bronchus smooth muscle, and its effect is slow and lasting.The common alpha streptococcus of respiratory tract, staphylococcus aureus, Diplococcus pneumoniae, micrococcus catarrhalis etc. all there is good inhibitory effect.
Herba Houttuyniae: acrid in the mouth.Cool in nature.Slightly poisonous.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.It is about 0.05% that Herba Houttuyniae contains volatile oil, contains the positive nonanone of base, myrcene, capric acid, certain herbaceous plants with big flowers aldehyde, lauryl aldehyde, zest cordarine, potassium salt, houttuynine sodium bisulfite in the oil.Herba Houttuyniae is to Hemolytic streptococcus, staphylococcus aureus, hemophilus influenza, micrococcus catarrhalis, streptococcus pneumoniae, escherichia coli, dysentery bacterium, repair cold bacillus stronger bacteriostasis is all arranged, houttuynine sodium bisulfite can strengthen the leukocytes phagocytic ability and improve serum Jie's element fully, can regulate the defence factor of animal body own, so except that antibacterial action, on human body immunity improving power, also have very important significance.
Pericarpium Citri Reticulatae: bitter in the mouth, suffering.Warm in nature.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Pericarpium Citri Reticulatae contains volatile oil 1.5～4%, and wherein 80～97% is citric acid, 10% for γ-Song Youxi, contain Hesperidin 6.35～9.93%, naringenin, hesperetin, Pericarpium Citri tangerinae contain pectin 12%.Pericarpium Citri Reticulatae has eliminating phlegm and relieving asthma and antitussive effect, and volatile oil has the zest phlegm-dispelling functions, and bronchus is had dilating effect, and bronchial asthma is had certain curative effect, intensity.
Caulis Gneti Parvifolii: bitter in the mouth.Slightly warm in nature.Expelling wind and activating blood circulation, reducing swelling and alleviating pain, preventing phlegm from forming and stopping coughing.Caulis Gneti Parvifolii contains alkaloid, oils and fats, phenolic substance etc.1. relieving asthma: Caulis Gneti Parvifolii contains the water solublity alkaloid, and bronchial smooth muscle is had direct dilating effect, and the effect of alleviating bronchial muscular spasm is arranged; 2. antiinflammatory is arranged and repair the pathological tissues effect, behind Caulis Gneti Parvifolii treatment bronchitis, sucutaneous nodule in the sputum and neutrophil cell reduce, pricker hair columnar epithelium II, III level obviously reduce, cytopathy alleviates, the hemophilus influenza virulence obviously weakens, and prompting has the effect that improves the body defence capability and promote the pathological changes reparation; 3. desensitization: acidophil obviously reduces in the peripheral blood of treatment back; 4. Caulis Gneti Parvifolii water decoction and fat-soluble biological alkali are to Diplococcus pneumoniae alpha streptococcus medium sensitivity, extremely sensitive to hemophilus influenza.
Folium Pyrrosiae: leaf hardship, sweet.Cool in nature.Diuretic calculus, lung heat clearing purge heat, stop blooding.Folium Pyrrosiae contains sitosterol and bright and beautiful horse triterpene.The Folium Pyrrosiae water drug-decocting concentrating liquid has antitussive and phlegm-dispelling functions.Expectorant reduced gradually after patient took medicine 24 hours, the thinning easy expectoration of sputum, emptying the long-pending expectorant of respiratory tract, thereby improved patient's respiratory function, alleviated because of the infringement of secondary infection trachea, bronchial mucosa epithelium, strengthened its more reactivation power.After the treatment, the quantity of large mononuclear cell increases to some extent, and cytophagous phagocytic activity also helps the effect that pathological changes is repaired in enhancing.
Folium Elaeagni: mildly bitter flavor.Property is put down.Relieving cough and asthma.Folium Elaeagni contains tannin organic acid, saccharide, fat and oxalates etc.Folium Elaeagni has certain curative effect to bronchitis, and the bronchus pathology variation of treatment back has clear improvement, and most of epithelial cells can both be repaired, and gradually normal.
Each medicine of the present invention is learnt from other's strong points to offset one's weaknesses at the cause of disease, and therapeutic effect is reliable, and instant effect has desensitization, adjusts the effect of autonomic nervous dysfunction, and tracheal smooth muscle is had direct dilating effect.Can alleviate bronchial muscular spasm, sucutaneous nodule and neutrophil cell epithelial cell are reduced, cytopathy alleviates, and causes the pathogenic bacteria virulence obviously to weaken.Have and improve the body defence capability, promote the pathological changes reparation, make cough, expectorant, breathe heavily, symptom such as pulmonary's wheezing sound takes a turn for the better the curative effect more than ninety percent.
Clinical verification:
1, clinical data:
The present invention verifies chronic bronchitis patient 117 examples, and all patients all meet the chronic bronchitis diagnostic criteria.After diagnosis is clear and definite, be divided into two groups, 60 examples are organized in treatment, male patient's 35 examples, and women patient's 25 examples, at 50～65 years old age, average 60 years old, the course of disease did not wait in 3～6 years; Matched group 57 examples, male patient's 30 examples, women patient's 27 examples, at 50～68 years old age, average 61 years old, the course of disease did not wait in 3～6 years.
2, Therapeutic Method:
Matched group is treated with traditional method, and is unobstructed from the maintenance breathing, treatments such as infection, hormone, antitussive and relieving cough and asthma.Treatment group Drug therapy of the present invention.Two groups of patients all take medicine continuously, and one month is a course of treatment.
3, judgment criteria:
Cure: clinical symptoms and pulmonary rale obviously disappear, and X line Chest X-rays shade disappears;
Effectively: clinical symptoms disappears substantially, and pulmonary rale obviously reduces, and X line Chest X-rays dash area absorbs;
Invalid: clinical symptoms and X ray examination do not have significant change.
4, therapeutic outcome:
The treatment group: totally 60 examples, cure 53 examples, account for 88.3%, effective 5 examples account for 8.3%, and invalid 2 examples account for 3.3%; Total effective rate is 96.6%.
Matched group: totally 57 examples, cure 43 examples, account for 72%, effective 4 examples account for 7%, and invalid 10 examples account for 17.5%; Total effective rate is 82.5%.
The result shows that treatment group and matched group compare, and the difference significance illustrates that the therapeutic effect of treatment group obviously is better than matched group.
Model case:
Case 1: Zhao so-and-so, man, 60 years old.First visit on October 13 in 2002, the patient coughs, spits, asthma, uncomfortable in chest, the repeated cold several years, especially with night for very.Once examined and be chronic bronchitis, bronchial asthma, emphysema, informal dress is with Western medicine, transfusion, antibiotic and expansion trachea class medicine, and curative effect is not good enough, and the spy comes diagnosis and treatment.Examine its stringy and rolling pulse, pale tongue is fat, and tongue is greasy in vain, lung ring pitch, with throwing medicament capsule of the present invention, every day 3 times, each 4, logotype 5 days, the further consultation patient coughs and obviously alleviates, and amount of expectoration reduces, the alleviation to some extent uncomfortable in chest of panting, lung ring sound weakens, and obeys this medicament capsule again 15 days, further consultation once more on January 16 in 2003, the patient coughs, expectorant, breathe heavily fully and to alleviate, lung ring sound extremely a little less than, advise the patient to obey medicament capsule of the present invention again 30 days, 2 times on the 1st, 1 time 4, with kind thereafter.
Case 2: Liu so-and-so, man, 39 years old.First visit on January 18 in 2005, the patient is from 9 years old cause flu suffer from cold concurrent cough, asthma, after treatment takes a turn for the better, cold whenever later on i.e. cough gradually increases the weight of, though not good through the each side therapeutic effect.Each in recent years outbreak is that half the circumference of the sleeve where it joins the shoulder is faced upward and breathed heavily, and shape is very painful, uses ephedrine aminophylline etc. and can not end, and postpones 20～30 minutes with adrenergic, and quiet medicine such as hormone generally takes about one day and could alleviate.The spy comes diagnosis and treatment, thin and weak, the lusterless complexion of this patient's body, and thready pulse without strength, the pale tongue no fur, lung ring sound is high, throws medicament capsule of the present invention 10 days, and every day 4 times, each 4, further consultation after 10 days is breathed heavily greatly and is subtracted, and continue and threw this medicament capsule 30 days, 3 times on the 1st, each 4.When coming further consultation once more, patient row is as ordinary person, only feels uncomfortable in chest with the smoking people together the time, advises patient's logotype half a year again, to be apt to thereafter.
Case 3: Wu so-and-so, woman, 45 years old.On November 25th, 2004 examined, and the patient coughed, coughs up phlegm, pants 7 years, the empty spontaneous perspiration of body, and repeated cold, the flu back state of an illness increases the weight of, and nearly first quarter moon cough, breathes heavily very acutely, and dyspnea can not be put down for sleeping inly, once uses the western medicines in treatment poor effect.The spy comes diagnosis and treatment, and the patient is with dizziness, shortness of breath and palpitation, pale tongue, white and thin fur, deep and faint pulse is sliding, is diagnosed as chronic bronchitis through Chest X-rays and merges emphysema, with throwing medicament capsule of the present invention 5 days, 4 times on the 1st, each 6, cough with asthma subtracts greatly during further consultation, and amount of expectoration reduces, continue and threw this medicament capsule 20 days, every day 3 times, each 5, further consultation again after 20 days, all diseases seemingly have like not having, and advise the patient to continue and obey this medicament capsule 100 days, 2 times on the 1st, each 4, to be apt to thereafter.
The specific embodiment:
For clearly demonstrating the technical characterstic of this programme, below by the specific embodiment, the present invention will be described in detail.
Embodiment 1: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 100g, gallbladder powder 150g, Herba Houttuyniae 100g, Pericarpium Citri Reticulatae 100g, Caulis Gneti Parvifolii 150g, Folium Pyrrosiae 150g, Folium Elaeagni 150g by following raw materials by weight proportions.
Preparation of the present invention and instructions of taking are as follows: take by weighing Fructus Nandinae Domesticae, gallbladder powder, Pericarpium Citri Reticulatae, Herba Houttuyniae by weight ratio and cross 400 mesh sieves to make medicated powder standby; Take by weighing Caulis Gneti Parvifolii, Folium Pyrrosiae, Folium Elaeagni again and cross 60 mesh sieves, these three kinds of raw materials are added decocting filter half an hour, connect and fry in shallow oil three times, it is standby that three filtrate is condensed into scattered paste shape; Be placed on drying baker inner drying, sterilization after medicated powder and mass stirred, incapsulate then and get final product.This medicine is taken 3 times every day, and each 4, one after each meal also can be according to conditions of patients proper transformation dose.
Embodiment 2: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 120g, gallbladder powder 200g, Herba Houttuyniae 120g, Pericarpium Citri Reticulatae 120g, Caulis Gneti Parvifolii 200g, Folium Pyrrosiae 200g, Folium Elaeagni 200g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 3: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 110g, gallbladder powder 180g, Herba Houttuyniae 110g, Pericarpium Citri Reticulatae 110g, Caulis Gneti Parvifolii 180g, Folium Pyrrosiae 180g, Folium Elaeagni 180g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 4: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 105g, gallbladder powder 160g, Herba Houttuyniae 105g, Pericarpium Citri Reticulatae 105g, Caulis Gneti Parvifolii 160g, Folium Pyrrosiae 160g, Folium Elaeagni 160g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 5: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 115g, gallbladder powder 185g, Herba Houttuyniae 115g, Pericarpium Citri Reticulatae 115g, Caulis Gneti Parvifolii 185g, Folium Pyrrosiae 185g, Folium Elaeagni 185g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 6: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 100g, gallbladder powder 160g, Herba Houttuyniae 120g, Pericarpium Citri Reticulatae 100g, Caulis Gneti Parvifolii 150g, Folium Pyrrosiae 150g, Folium Elaeagni 160g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 7: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 120g, gallbladder powder 150g, Herba Houttuyniae 100g, Pericarpium Citri Reticulatae 100g, Caulis Gneti Parvifolii 200g, Folium Pyrrosiae 180g, Folium Elaeagni 200g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 8: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 112g, gallbladder powder 170g, Herba Houttuyniae 112g, Pericarpium Citri Reticulatae 110g, Caulis Gneti Parvifolii 170g, Folium Pyrrosiae 165g, Folium Elaeagni 170g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Embodiment 9: a kind of medicine for the treatment of chronic bronchitis, mainly make: Fructus Nandinae Domesticae 106g, gallbladder powder 175g, Herba Houttuyniae 106g, Pericarpium Citri Reticulatae 106g, Caulis Gneti Parvifolii 180g, Folium Pyrrosiae 175g, Folium Elaeagni 180g by following raw materials by weight proportions.
Preparation and instructions of taking are with embodiment one.
Claims (1)
1. medicine for the treatment of chronic bronchitis, it is characterized in that: mainly make: Fructus Nandinae Domesticae 100～120g by following raw materials by weight proportions, gallbladder powder 150～200g, Herba Houttuyniae 100～120g, Pericarpium Citri Reticulatae 100～120g, Caulis Gneti Parvifolii 150～200g, Folium Pyrrosiae 150～200g, Folium Elaeagni 150～200g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100154189A CN101554425B (en) | 2009-05-18 | 2009-05-18 | Drug for curing chronic bronchitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100154189A CN101554425B (en) | 2009-05-18 | 2009-05-18 | Drug for curing chronic bronchitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101554425A CN101554425A (en) | 2009-10-14 |
| CN101554425B true CN101554425B (en) | 2011-02-16 |
Family
ID=41172807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009100154189A Expired - Fee Related CN101554425B (en) | 2009-05-18 | 2009-05-18 | Drug for curing chronic bronchitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101554425B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104431183A (en) * | 2014-12-05 | 2015-03-25 | 蓝子花 | Health tea of walton's lepisorus |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101396536A (en) * | 2007-09-30 | 2009-04-01 | 天津瑞普生物技术集团有限公司 | Traditional Chinese medicine oral liquid for treating livestock and poultry respiratory disease |
-
2009
- 2009-05-18 CN CN2009100154189A patent/CN101554425B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101396536A (en) * | 2007-09-30 | 2009-04-01 | 天津瑞普生物技术集团有限公司 | Traditional Chinese medicine oral liquid for treating livestock and poultry respiratory disease |
Non-Patent Citations (3)
| Title |
|---|
| 戴克敏.姜春华治疗咳喘验方.《山西中医》.2007,第23卷(第4期),9-10页. * |
| 汤小虎等.痰喘消胶囊治疗慢性阻塞性肺疾病痰热瘀阻证的临床观察.《云南中医学院学报》.2006,第29卷(第6期),33-34页. * |
| 马榕花.肖诏玮主任运用"二麻蠲喘汤"的经验分析.《福建中医药》.2008,第39卷(第2期),15-16页. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101554425A (en) | 2009-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102613566A (en) | Health care product for relaxing bowel and preparation method of heath care product | |
| CN102614323B (en) | Method for preparing atomized liquid for treating infantile asthmatic suffocating pneumonia | |
| CN104306793B (en) | A kind of Chinese medicine preparation for treating lobar pneumonia | |
| CN103735780B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of chronic bronchitis | |
| CN101554425B (en) | Drug for curing chronic bronchitis | |
| CN101642537B (en) | Cough-relieving traditional Chinese medicine | |
| CN101869653B (en) | Chinese medicinal preparation for treating chronic nasosinusitis and preparation method thereof | |
| CN103830481B (en) | The medicine for the treatment of infantile respiratory tract infection repeatedly | |
| CN103120793A (en) | Traditional Chinese medicine composition for preventing and treating recurrent respiratory tract infection of children and application thereof | |
| CN108714172B (en) | Solid beverage for reducing fat and losing weight and preparation method thereof | |
| CN106038975A (en) | Traditional Chinese medicine composition having function of suppressing cough and preparation method and application of traditional Chinese medicine composition | |
| CN105853562A (en) | Pharmaceutical preparation for treating asthma and preparing method | |
| CN104815151A (en) | Traditional Chinese medicine for treating warm-dryness lung injury type cough | |
| CN101181448A (en) | Oral administration proprietary Chinese medicine for curing facial palsy | |
| CN101125187A (en) | Traditional Chinese medicinal plaster for treating pulmonary tuberculosis | |
| CN104474045A (en) | Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch | |
| CN104888065B (en) | For treating Chinese medicine composition, preparation and its application of cough | |
| CN103520550A (en) | Traditional Chinese medicine for treating external cold internal rheum type chronic bronchitis and preparation method thereof | |
| CN102580020A (en) | Traditional Chinese medicine composition for curing asthma | |
| CN102319290B (en) | Medicament for preventing cancer cells from proliferating to lungs after radiation treatment of nasopharyngeal darcinoma | |
| CN101181500B (en) | Externally used medicament for curing respiratory system disease and preparation method thereof | |
| CN104258361A (en) | Traditional Chinese medicine composition for treating infantile asthma | |
| CN105288325A (en) | Traditional Chinese medicine for treating arrhythmia caused by deficiency of both vital energy and yin | |
| CN105168788A (en) | Traditional Chinese medicinal preparation for treating chronic bronchitis | |
| CN104784567B (en) | A kind of pharmaceutical composition for the treatment of urinary system infection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110216 Termination date: 20140518 |