CN101554423B - Dealcoholic sobering-up pharmaceutical preparation and preparing method thereof - Google Patents
Dealcoholic sobering-up pharmaceutical preparation and preparing method thereof Download PDFInfo
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- CN101554423B CN101554423B CN2009103023381A CN200910302338A CN101554423B CN 101554423 B CN101554423 B CN 101554423B CN 2009103023381 A CN2009103023381 A CN 2009103023381A CN 200910302338 A CN200910302338 A CN 200910302338A CN 101554423 B CN101554423 B CN 101554423B
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a dealcoholic sobering-up pharmaceutical preparation and a preparing method thereof; the pharmaceutical preparation is prepared by poria, hawthorn, pueraria, ganoderma lucidum,and hoveniae semoveniae semen. Compared with the prior art, the pharmaceutical preparation has very significant dealcoholic sobering-up effect, protects gastric mucosa, does not hurt the gaster, adju sts gastric motility in two ways, inhibits vomiting, nausea and abdominal distention, directly decomposes alcohol and improves capacity for liquor, resists hypnosis and alleviates headache and head halo, speeds up the emptying time of alcohol in the intestine and gaster, reduces the metabolism burden of the liver and kidney, accelerates the alcohol metabolism in the blood, protects the liver, enhances the immunity and relieves the fatigue. The pharmaceutical preparation is prepared by pure natural plants, and has less medicinal odor, easy quality control, and excellent effects for protecting liver, nourishing gaster and strengthening spleen.
Description
Technical field
The present invention relates to preparation of a kind of Dealcoholic sobering-up and preparation method thereof.
Background technology
China is the native place of wine, and in 5,000 years historical long rivers of the Chinese nation, wine and drinks culture are always in occupation of critical role.China is the kingdom of wine, and form is multifarious, and color and luster appears.China is again wine people's the land of happiness, and ground does not have branch north and south, and the people does not have the branch men and women, old and young, and family does not have the branch Chinese and completely covers go back to the Tibetan, and the wind of drinking is gone through thousands of year and do not waned.China is the golden ground of spirits culture especially, and the meaning of drinking is far above physiological consumption, is far above the pleasure of food, and in many occasions, it all is as a cultural Symbol, and a kind of cultural consumption is used for representing a kind of ceremony, a kind of atmosphere, a kind of temperament and interest, a kind of mental state.
But excessive consumption of alcohol is again very deleterious to health, ethanol can suppress the respiratory center of medulla oblongata, cause respiratory arrest, can cause that also various vitamins shortages cause multiple nervous system injury indirectly, secular heavy drinking can cause athero to cause fatty liver, gastric ulcer, injury nervous system, cerebral cortex atrophy etc. at liver, long-term a large amount of also inevasible liver cirrhosis that causes of drinking, or the like.So, inevitably should in time ethanol excreted behind the heavy drinking, to reduce the injury of ethanol to health.
Summary of the invention
Technical problem to be solved by this invention provides a kind of Dealcoholic sobering-up preparation, and a kind of preparation method of said preparation is provided simultaneously.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme:
According to listed as parts by weight, Dealcoholic sobering-up preparation of the present invention is to be prepared from for 60～100 parts by 100～140 parts in Poria, 100～140 parts of Fructus Crataegis, 100～140 parts of Radix Puerariaes, 100～140 parts of Ganodermas and Semen Hoveniae (Fructus Hoveniae).
Further, above-mentioned preparation is to be prepared from for 70～90 parts by 110～130 parts in Poria, 110～130 parts of Fructus Crataegis, 110～130 parts of Radix Puerariaes, 110～130 parts of Ganodermas and Semen Hoveniae (Fructus Hoveniae).
Preferably, aforementioned Dealcoholic sobering-up preparation is to be prepared from for 78 parts by 118 parts in Poria, 118 parts of Fructus Crataegis, 118 parts of Radix Puerariaes, 118 parts of Ganodermas and Semen Hoveniae (Fructus Hoveniae).
The present invention also provides a kind of preferred for preparation method of aforementioned Dealcoholic sobering-up preparation: get Radix Puerariae and pulverize standby; Other gets Poria, Fructus Crataegi, Ganoderma and Semen Hoveniae (Fructus Hoveniae) extracting in water, and extracting solution is condensed into extractum, adds powder of Radix Puerariae, mix homogeneously, and drying is pulverized, and makes various preparations according to a conventional method.
Further, the preparation method of above-mentioned Dealcoholic sobering-up preparation is: get Radix Puerariae, pulverize, and standby; Poria, Fructus Crataegi, Ganoderma and Semen Hoveniae (Fructus Hoveniae) add 6～10 times of water gaging mercerations 30～120 minutes, be heated to 100 ℃, kept 20～40 minutes, reflux, extract, is 2～3 hours then, extracting liquid filtering, be concentrated into 50～60 ℃ of relative densities and be 1.15～1.20 extractum, add powder of Radix Puerariae, mix homogeneously, drying, pulverize, make various preparations according to a conventional method.
Preferably, aforementioned preparation method is: get Radix Puerariae, pulverize, cross 80 mesh sieves, and standby; The Semen Hoveniae (Fructus Hoveniae) muslin bag of packing into seals and Poria, Fructus Crataegi, Ganoderma add 8 times of water gaging mercerations 30～120 minutes together, be heated to 100 ℃, kept reflux, extract, 2.5 hours 30 minutes, extracting liquid filtering, it is 1.15～1.20 extractum that normal pressure is concentrated into 50～60 ℃ of relative densities, adds powder of Radix Puerariae, mix homogeneously, be dried to water content 2～4% at 92～98 ℃, pulverize, encapsulated, promptly get capsule.
Poria, sweet, light, equal, return lung, stomach, kidney channel, have the effect of anticancer, the diuretic dissipating fluid-retention of relieving internal heat, spleen invigorating mind calming.Fructus Crataegi (Crateagus pinnatifida), sour in the mouth, sweet, slightly warm in nature has the effect of appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.Radix Puerariae (Radix Puerariae), cool in nature, sweet in the mouth, suffering, having induces sweat brings down a fever, promote the production of body fluid, the effect of rash, yang invigorating antidiarrheal.Ganoderma, sweet, flat, GUIXIN, lung, liver, kidney channel cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.Semen Hoveniae (Fructus Hoveniae), sweet, flat, nontoxic, have the effect of relieving thirst and restlessness, alcoholic intoxication, diuresis.Five tastes crude drug is played the effect of Dealcoholic sobering-up altogether.
Below for taking the clinical example of capsule of the present invention (the refreshing capsule of Seedling king):
1, Chen Buyou, the man, 38 years old, Guizhou Luohan Food Co., Ltd lived the Guiyang Wudang District and newly adds the main road No. 114, drinks drinks: old natives family, the amount of drinking: 1 bottle (500ml), the refreshing dose of Seedling king: 3, take mode: take after drinking.
Oneself's impression: heart stomach is releived, vomiting, the phenomenon of feeling bad that the back of not drinking in the past occurs.
2, Dai Ling, the woman, 28 years old, Guizhou Province's Kaili City was lived by Guizhou Luohan Food Co., Ltd, drinks drinks: practise wine, the amount of drinking: 1 bottle (480ml), the refreshing dose of Seedling king: 6, take mode: drink after drinking.
Take the reflection of back health: the vomiting phenomenon do not occur, second top margin of a page can pain.
3, Wang Kexing, the man, 25 years old, profession was lived north, Nanming District Hua Xi main road, Guiyang section No. 242, and drink drinks: five-pointed star is practised wine, the amount of drinking: half jin, the refreshing dose of Seedling king: 3, take mode: take after drinking.
Oneself impression: stomach is not bitterly, and is not dizzy.
4, Sun Ping, the woman, 28 years old, service occupation lived the sloping deer of the big battalion in Guiyang and dashes pass road three rows No. 29, and drink drinks: five-pointed star is practised wine, the amount of drinking: three liang, the refreshing dose of Seedling king: 3, take mode: just before the meal.
Oneself's impression: after taking Seedling king god, do not have obvious drunk reaction, continue the bar drinks beer, serious when the sensation spinning sensation is not taken Seedling king god.
5, pay the Yadong, the man, 46 years old, the chief of office of Guizhou Aerospace Control Technology Co., Ltd, the refreshing dose of Seedling king: 3, take mode: wine reached and takes after drinking in preceding 30 minutes.
Oneself impression: after taking 3 Seedling king god, sensation capacity for liquor has increased than usual, and liver and gastropathy all not have pain and have an attack of one's old illness, and second god's clearing heat in QI system is felt well very comfortable.
6, Dong Zejun, the woman, 35 years old, power sky, Zun Yi general manager of health products Co., Ltd, the refreshing dose of Seedling king: 3, take mode: wine reached and takes after drinking in preceding 30 minutes.
Oneself impression: after drinking, stomach is not felt bad, and is not dizzy.
7, Sun Botao, the man, 51 years old, No. 23 2 Unit 3s of north, city flower small stream main road, Kweiyang section were lived No. 18 by Guizhou National Pharmaceutical Co., Ltd.
Oneself's impression: in late December, 2007, during difference was taken in Nanning, Guangzhou one out of, many because of commercial activity, every day, the commercial affairs dinner party was drunk frequent.Therefore in the past few days; before going at dusk dinner every day; the capital is sold in half multi-pin before the meal and is taken 3 of the refreshing capsules of Seedling king respectively; as usual drink afterwards; the about 3-4 two of everyone drinking amount; with do not take Seedling king god at ordinary times and compare; feel that obviously after drinking relatively easily head can not swollen yet, stomach is not felt bad yet; after particularly getting up second day morning; show no sign of the back giddy in morning next day of drinking the sort of evening, have no appetite, bitter sensation is sent out in the oral cavity; so; feel deeply in commercial affairs; in the increasing economic life of the dinner party of government affairs aspect, refreshing unique " relieving the effect of alcohol; the protect stomach " effect of Seedling king is particularly suitable for the frequent personage of this respect dinner party; should conduct vigorous propaganda popularization, protect numerous alcohol users' health.
8, analogy ring dawn, the man, 35 years old, the expensive black road of Guiyang Yunyan District was lived No. 128 by Guizhou National Pharmaceutical Co., Ltd.
Oneself's impression: after taking Seedling king god, drink, obviously feel capacity for liquor than increase in the past, and do not have giddy, headache, phenomenons such as gastrointestinal upset, and next day, the mental status was good, had no side effect.
9, Zhao Guanghe, the man, 33 years old, profession was lived outer shroud city east, Guiyang road No. 202.
Oneself impression: during the feast, 3 people have drunk 2 kilograms of Seedlings man rice wine (about 38 degree) altogether and since before the wine half an hour taken the refreshing capsules of 3 Seedling kings, therefore do not vomit after drinking, dizzy phenomenon.It is good after the back spirit of getting up in second day is drunk more at ordinary times.
10, Cai Qiang, the man, 37 years old, Guizhou centre halfback medicine company limited was lived No. 20 1 unit, Xiaohe District Zhujiang River road, Guiyang No. 11.
Oneself's impression: on March 21st, 2009, with friend's party, at about about 40 minutes before the meal, take 3 of the refreshing capsule 0.4g of Seedling king, drink about about 7 liang of 53 degree Chinese liquor, dizzy a little phenomenon is arranged after drinking, but conscious, take people's about about half jin of capacity for liquor at ordinary times, stomach can appear in back health next day of drinking at ordinary times feels bad, and does not feel like a meal phenomenons such as headache, but after taking Seedling king god, next day, above malaise symptoms did not appear in health.
11, Cai Lei, the man, 30 years old, the Guizhou flourishing age scientific ﹠ technical corporation, live Papilio xuthus (Linne) lane, road, Yunyan District Beijing, Guiyang.
Oneself's impression: April 14 in 2009 day and night, when friend family dines together, about about half jin of drinking white spirit, take the people after 5 bottles of the medicated beer and obnubilation occurred, vomit three times situation, took 6 of the refreshing capsules of Seedling king after about one hour after drinking, mind is recovered normally gradually after half an hour approximately, does not occur the vomiting phenomenon once more.Morning next day, clear-headed back took with nothing that " Seedling king god " feel to take and do not have uncomfortable phenomenon in back second day by the capsule back contrast of drinking.
12, Liang Chunhua, the man, 44 years old, Flos Nelumbinis slope, Guiyang was lived No. 47 by Guizhou centre halfback pharmaceuticals,
Oneself's impression: drank 53 degree Chinese liquor (Maotai Zhen is produced) preceding 30 minutes, and took refreshing 3 of Seedling king, the sensation stomach is not felt bad, and second top margin of a page is not dizzy, and not bitterly, the health mental status is fine, is difficult to be subjected to unlike after drinking in the past, has a stomach upset.Headache.
13, Deng Sixiong, the man, 33 years old, 72 unit, Xiaohe District oriental cherry garden, Kweiyang were lived No. 2 by Guizhou National Pharmaceutical Co., Ltd.
Oneself impression: drink five-pointed star with friend and practise wine, capacity for liquor is 3 liang at ordinary times, take refreshing 3 of Seedling king earlier after, 6 people have drunk 4 bottles of wine altogether, it is fine to finish off aftersensation, much better than usual, the sensation of not feeling sick, kecking.
14, Chen Guangmeng, man, 41 years old, coal road, Yun Yan road, Guiyang is lived No. 43 by the Wu Chuan county public security bureau.
Oneself impression: behind the edible seedling king god, drinking 53 degree Chinese liquor has increased about about 3 liang than usual, and sensation is not had a headache, do not feel bad, particularly second day very clear-headed, do not have drunk sense.
15, Long Yanping, the woman, 34 years old, profession was lived the prosperous garden of Kweiyang river.
Oneself's impression: take Seedling king god before drinking, drink 53 degree Chinese liquor, do not tell, stomach is not felt bad, and capacity for liquor was not twice than not taking Seedling king god in the past.
Compared with prior art, Dealcoholic sobering-up preparation of the present invention is formulated according to Seedling medical knowledge opinion, and its Dealcoholic sobering-up effect is very remarkable, and the effect of hepatoprotective, nourishing the stomach, spleen invigorating is splendid, specifically:
1, the protection gastric mucosa does not injure one's stomach;
2, two-ways regulation gastric peristalsis suppresses vomiting, feels sick, abdomen rises;
3, direct decomposing alcohol improves capacity for liquor;
4, headache and dizzy is alleviated in anti-hypnosis;
5, accelerate the emptying time of ethanol in gastrointestinal, reduce metabolism burden liver, kidney;
6, alcohol metabolism in the accelerate blood, the liver protecting;
7, human body immunity improving power is alleviated weak;
8, pure natural plant is made, and flavour of a drug are few, and quality is easy to control.
The specific embodiment
Embodiment 1: gets the clean Radix Puerariae 118kg that removes cork, pulverizes, cross 80 mesh sieves, and standby.Get Semen Hoveniae (Fructus Hoveniae) 78kg, the byssus bag of packing into, the size of byssus bag is no more than the cloth bag of tightening behind the bag mouth volumetrical 1/2 with loading amount and is advisable, and other gets Poria 118kg, Fructus Crataegi 118kg and Ganoderma 118kg, place with the cloth bag that Semen Hoveniae (Fructus Hoveniae) is housed, add 8 times of water gagings, merceration 100 minutes boils, keeping little boiled 30 minutes, reflux, extract, is 2.5 hours then, and it is 1.15～1.20 extractum that extracting liquid filtering, filtrate normal pressure are concentrated into 50～60 ℃ of relative densities.Add the Radix Puerariae fine powder in extractum, mix homogeneously is dried to water content 2～4% at 96 ℃, pulverizes, and is encapsulated, makes 400,000 of capsules.
Nomenclature of drug: the refreshing capsule of Seedling king.
The scope of application: to the dizziness that causes after drinking, headache, feel sick, vomiting, agitation have the alleviation restitution.
Usage and dosage: edible before or after drinking, each 3.
Embodiment 2: gets the clean Radix Puerariae 125kg that removes cork, pulverizes, and standby.Other gets Poria 110kg, Fructus Crataegi 110kg, Ganoderma 115kg and Semen Hoveniae (Fructus Hoveniae) 85kg, adds 10 times of water gaging mercerations 30 minutes, boils, keeping little boiled 20 minutes, reflux, extract, 3 hours, extracting liquid filtering, it is 1.15～1.20 extractum that filtrate is concentrated into 50～60 ℃ of relative densities.In extractum, add powder of Radix Puerariae, mix homogeneously, drying is pulverized, and tabletting is made 400,000 in tablet according to a conventional method.
Usage and dosage: edible before or after drinking, each 3.
Embodiment 3: gets clean Radix Puerariae 115kg, the pulverizing of removing cork, crosses 80 mesh sieves, and standby.Get Semen Hoveniae (Fructus Hoveniae) 75kg, the muslin bag of packing into, other gets Poria 130kg, Fructus Crataegi 130kg, Ganoderma 125kg, with Semen Hoveniae (Fructus Hoveniae) together, add 6 times of water gaging mercerations 120 minutes, boil, keeping little boiled 40 minutes, reflux, extract, 2 hours, extracting liquid filtering, it is 1.15～1.20 extractum that filtrate is concentrated into 50～60 ℃ of relative densities.In extractum, add powder of Radix Puerariae, mix homogeneously, drying is pulverized, and is encapsulated, makes 400,000 of capsules.
Embodiment 4: get raw material Poria 100kg, Fructus Crataegi 125kg, Radix Puerariae 100kg, Ganoderma 140kg and Semen Hoveniae (Fructus Hoveniae) 70kg, make 400,000 of capsules according to the method for embodiment 1.
Embodiment 5: get raw material Poria 140kg, Fructus Crataegi 140kg, Radix Puerariae 140kg, Ganoderma 100kg and Semen Hoveniae (Fructus Hoveniae) 100kg, make 400,000 in tablet according to the method for embodiment 2.
Claims (5)
1. Dealcoholic sobering-up preparation, it is characterized in that: according to listed as parts by weight, it is to be prepared from for 70～90 parts by 110～130 parts in Poria, 110～130 parts of Fructus Crataegis, 110～130 parts of Radix Puerariaes, 110～130 parts of Ganodermas and Semen Hoveniae (Fructus Hoveniae).
2. according to the described Dealcoholic sobering-up preparation of claim 1, it is characterized in that: it is to be prepared from for 78 parts by 118 parts in Poria, 118 parts of Fructus Crataegis, 118 parts of Radix Puerariaes, 118 parts of Ganodermas and Semen Hoveniae (Fructus Hoveniae).
3. the preparation method of claim 1 or 2 described Dealcoholic sobering-up preparations is characterized in that: get Radix Puerariae and pulverize standby; Other gets Poria, Fructus Crataegi, Ganoderma and Semen Hoveniae (Fructus Hoveniae) extracting in water, and extracting solution is condensed into extractum, adds powder of Radix Puerariae, mix homogeneously, and drying is pulverized, and makes various preparations according to a conventional method.
4. according to the preparation method of the described Dealcoholic sobering-up preparation of claim 3, it is characterized in that: get Radix Puerariae, pulverize, standby; Poria, Fructus Crataegi, Ganoderma and Semen Hoveniae (Fructus Hoveniae) add 6～10 times of water gaging mercerations 30～120 minutes, be heated to 100 ℃, kept 20～40 minutes, reflux, extract, is 2～3 hours then, extracting liquid filtering, be concentrated into 50～60 ℃ of relative densities and be 1.15～1.20 extractum, add powder of Radix Puerariae, mix homogeneously, drying, pulverize, make various preparations according to a conventional method.
5. according to the preparation method of the described Dealcoholic sobering-up preparation of claim 4, it is characterized in that: get Radix Puerariae, pulverize, cross 80 mesh sieves, standby; The Semen Hoveniae (Fructus Hoveniae) muslin bag of packing into seals and Poria, Fructus Crataegi, Ganoderma add 8 times of water gaging mercerations 30～120 minutes together, be heated to 100 ℃, kept reflux, extract, 2.5 hours 30 minutes, extracting liquid filtering, it is 1.15～1.20 extractum that normal pressure is concentrated into 50～60 ℃ of relative densities, adds powder of Radix Puerariae, mix homogeneously, be dried to water content 2～4% at 92～98 ℃, pulverize, encapsulated, promptly get capsule.
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| CN102552493A (en) * | 2012-02-02 | 2012-07-11 | 贵州益佰制药股份有限公司 | Anti-inebriation drunk-preventing composition and preparation method thereof |
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| CN102552493A (en) * | 2012-02-02 | 2012-07-11 | 贵州益佰制药股份有限公司 | Anti-inebriation drunk-preventing composition and preparation method thereof |
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