CN101554358B - 淡型乳液 - Google Patents
淡型乳液 Download PDFInfo
- Publication number
- CN101554358B CN101554358B CN 200810087575 CN200810087575A CN101554358B CN 101554358 B CN101554358 B CN 101554358B CN 200810087575 CN200810087575 CN 200810087575 CN 200810087575 A CN200810087575 A CN 200810087575A CN 101554358 B CN101554358 B CN 101554358B
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- China
- Prior art keywords
- weight
- ester
- acid
- group
- ethylhexyl
- Prior art date
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- 239000000839 emulsion Substances 0.000 title abstract description 17
- 239000012530 fluid Substances 0.000 title abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000000463 material Substances 0.000 claims abstract description 8
- NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 claims abstract description 6
- DZKXJUASMGQEMA-UHFFFAOYSA-N tetradecyl tetradecanoate Chemical compound CCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCC DZKXJUASMGQEMA-UHFFFAOYSA-N 0.000 claims abstract description 5
- 238000002360 preparation method Methods 0.000 claims description 50
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 20
- -1 2-ethylhexyl Chemical group 0.000 claims description 19
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 239000008271 cosmetic emulsion Substances 0.000 claims description 12
- 150000002148 esters Chemical class 0.000 claims description 12
- 238000001914 filtration Methods 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 11
- 239000004408 titanium dioxide Substances 0.000 claims description 11
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 10
- 238000009472 formulation Methods 0.000 claims description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 8
- 229920001577 copolymer Polymers 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
- 230000003711 photoprotective effect Effects 0.000 claims description 7
- 229920000881 Modified starch Polymers 0.000 claims description 6
- 229920002472 Starch Polymers 0.000 claims description 6
- DLAHAXOYRFRPFQ-UHFFFAOYSA-N dodecyl benzoate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC=CC=C1 DLAHAXOYRFRPFQ-UHFFFAOYSA-N 0.000 claims description 6
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical class N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 claims description 6
- 235000019426 modified starch Nutrition 0.000 claims description 6
- 239000008107 starch Substances 0.000 claims description 6
- 235000019698 starch Nutrition 0.000 claims description 6
- ZEMPKEQAKRGZGQ-AAKVHIHISA-N 2,3-bis[[(z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (z)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCCC(O)C\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CC(O)CCCCCC)COC(=O)CCCCCCC\C=C/CC(O)CCCCCC ZEMPKEQAKRGZGQ-AAKVHIHISA-N 0.000 claims description 5
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 5
- 125000005456 glyceride group Chemical group 0.000 claims description 5
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 5
- 235000013826 starch sodium octenyl succinate Nutrition 0.000 claims description 5
- 239000001334 starch sodium octenyl succinate Substances 0.000 claims description 5
- 229940025250 camphora Drugs 0.000 claims description 4
- 239000010238 camphora Substances 0.000 claims description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 4
- 239000011787 zinc oxide Substances 0.000 claims description 4
- AFDXODALSZRGIH-QPJJXVBHSA-N (E)-3-(4-methoxyphenyl)prop-2-enoic acid Chemical compound COC1=CC=C(\C=C\C(O)=O)C=C1 AFDXODALSZRGIH-QPJJXVBHSA-N 0.000 claims description 3
- FIDRAVVQGKNYQK-UHFFFAOYSA-N 1,2,3,4-tetrahydrotriazine Chemical compound C1NNNC=C1 FIDRAVVQGKNYQK-UHFFFAOYSA-N 0.000 claims description 3
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 claims description 3
- NPSJHQMIVNJLNN-UHFFFAOYSA-N 2-ethylhexyl 4-nitrobenzoate Chemical compound CCCCC(CC)COC(=O)C1=CC=C([N+]([O-])=O)C=C1 NPSJHQMIVNJLNN-UHFFFAOYSA-N 0.000 claims description 3
- 239000004808 2-ethylhexylester Substances 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 3
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 claims description 3
- 125000001841 imino group Chemical group [H]N=* 0.000 claims description 3
- 239000004615 ingredient Substances 0.000 claims description 3
- DZVCFNFOPIZQKX-LTHRDKTGSA-M merocyanine Chemical compound [Na+].O=C1N(CCCC)C(=O)N(CCCC)C(=O)C1=C\C=C\C=C/1N(CCCS([O-])(=O)=O)C2=CC=CC=C2O\1 DZVCFNFOPIZQKX-LTHRDKTGSA-M 0.000 claims description 3
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- AFDXODALSZRGIH-UHFFFAOYSA-N p-coumaric acid methyl ether Natural products COC1=CC=C(C=CC(O)=O)C=C1 AFDXODALSZRGIH-UHFFFAOYSA-N 0.000 claims description 3
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-M 4-hydroxybenzoate Chemical compound OC1=CC=C(C([O-])=O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-M 0.000 claims description 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims description 2
- YSLWADNKXHLZBT-UHFFFAOYSA-N C(C)C(CCC(=O)NC=1C(NN=NC1CCCCCC)=O)CC Chemical compound C(C)C(CCC(=O)NC=1C(NN=NC1CCCCCC)=O)CC YSLWADNKXHLZBT-UHFFFAOYSA-N 0.000 claims description 2
- ICDPRTCSOCDUKQ-UHFFFAOYSA-N C1(CC(=O)OCO1)=O.C(C)C1=C(C=CC=C1)CC Chemical compound C1(CC(=O)OCO1)=O.C(C)C1=C(C=CC=C1)CC ICDPRTCSOCDUKQ-UHFFFAOYSA-N 0.000 claims description 2
- COPZLZQKXUPBFU-UHFFFAOYSA-N C=C(C(=O)O)C(=O)O.COC1=CC=CC=C1 Chemical compound C=C(C(=O)O)C(=O)O.COC1=CC=CC=C1 COPZLZQKXUPBFU-UHFFFAOYSA-N 0.000 claims description 2
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 2
- WYWZRNAHINYAEF-UHFFFAOYSA-N Padimate O Chemical compound CCCCC(CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-UHFFFAOYSA-N 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 2
- UBNYRXMKIIGMKK-UHFFFAOYSA-N amiloxate Chemical compound COC1=CC=C(C=CC(=O)OCCC(C)C)C=C1 UBNYRXMKIIGMKK-UHFFFAOYSA-N 0.000 claims description 2
- XVAMCHGMPYWHNL-UHFFFAOYSA-N bemotrizinol Chemical compound OC1=CC(OCC(CC)CCCC)=CC=C1C1=NC(C=2C=CC(OC)=CC=2)=NC(C=2C(=CC(OCC(CC)CCCC)=CC=2)O)=N1 XVAMCHGMPYWHNL-UHFFFAOYSA-N 0.000 claims description 2
- 229960004101 bemotrizinol Drugs 0.000 claims description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N benzene Substances C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 2
- 229940077388 benzenesulfonate Drugs 0.000 claims description 2
- SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 claims description 2
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 claims description 2
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical compound [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 2
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
- 229960004889 salicylic acid Drugs 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 2
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 2
- LVTJOONKWUXEFR-FZRMHRINSA-N protoneodioscin Natural products O(C[C@@H](CC[C@]1(O)[C@H](C)[C@@H]2[C@]3(C)[C@H]([C@H]4[C@@H]([C@]5(C)C(=CC4)C[C@@H](O[C@@H]4[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@H](CO)O4)CC5)CC3)C[C@@H]2O1)C)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1 LVTJOONKWUXEFR-FZRMHRINSA-N 0.000 claims 1
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 abstract description 5
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 abstract 2
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 238000010422 painting Methods 0.000 abstract 1
- GGHPAKFFUZUEKL-UHFFFAOYSA-M sodium;hexadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCOS([O-])(=O)=O GGHPAKFFUZUEKL-UHFFFAOYSA-M 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 230000002349 favourable effect Effects 0.000 description 9
- 239000003963 antioxidant agent Substances 0.000 description 8
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- 238000011156 evaluation Methods 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 7
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 6
- 230000003078 antioxidant effect Effects 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 235000011187 glycerol Nutrition 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 239000000230 xanthan gum Substances 0.000 description 6
- 235000010493 xanthan gum Nutrition 0.000 description 6
- 229920001285 xanthan gum Polymers 0.000 description 6
- 229940082509 xanthan gum Drugs 0.000 description 6
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 241001597008 Nomeidae Species 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 description 5
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 5
- 239000006210 lotion Substances 0.000 description 5
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 4
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 4
- 239000013543 active substance Substances 0.000 description 4
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- 230000000007 visual effect Effects 0.000 description 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 3
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
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- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 3
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- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 3
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- ANBFRLKBEIFNQU-UHFFFAOYSA-M potassium;octadecanoate Chemical compound [K+].CCCCCCCCCCCCCCCCCC([O-])=O ANBFRLKBEIFNQU-UHFFFAOYSA-M 0.000 description 3
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
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- PFPQMWRASYNLMZ-LGIMBNBCSA-N 2-(3,4-dihydroxyphenyl)-3-[(2s,3r,4r,5s,6r)-3,4-dihydroxy-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 PFPQMWRASYNLMZ-LGIMBNBCSA-N 0.000 description 2
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 2
- ZDHRAACDPXUCHC-UHFFFAOYSA-N 3,4-diethyl-2-hexoxyphenol;5-methoxy-4-phenyltriazine Chemical compound COC1=CN=NN=C1C1=CC=CC=C1.CCCCCCOC1=C(O)C=CC(CC)=C1CC ZDHRAACDPXUCHC-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 2
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Abstract
本发明公开了一种包含下列物质的组合的化妆乳状液:a)0.5至3重量%的硬脂酸甘油酯SE,b)1至5重量%的十六/十八醇,c)0.01至0.5重量%的PEG-40蓖麻油,和d)0.05至0.25重量%的十六/十八烷基硫酸钠,和e)0.5至3重量%的肉豆蔻酸十四烷基酯。
Description
技术领域
本发明涉及一种化妆乳液。
背景技术
让自己看起来美丽和迷人这个愿望,早已经根植于人类的心中。尽管随着时间的流逝美丽的典范经历了变化,但对没有瑕疵的外表的追求一直是人们的目标。美丽和迷人外表的一个重要组成部分是皮肤的状况和外观。
皮肤护理产品(和一些皮肤清洁产品)通常由乳状液组成。乳状液一般理解为由两种互相不可混合或者只可有限混合的液体组成的多相体系,所述液体通常称为相并且其中两种液体中的一种以极细小滴分散在另一种液体中。从外部用肉眼看乳状液是均质的。
如果两种液体是水和油,且油小滴精细分散在水中,则涉及一种水包油乳状液(O/W乳状液,例如奶)。O/W乳状液的基本特征受到水的深刻影响。油包水乳状液(W/O乳状液,例如黄油)则涉及相反的原则,即它的基本特征通过油来确定。
稀液的乳状液,即粘度为500至2500mPas,尤其优选粘度为1200至2000mPas的乳状液一般被称为“乳液”。乳液在使用中尤其受到喜爱,因为它容易分布在皮肤上并且很快渗入皮肤。除此之外,乳液在通常情况下是可喷的。粘度测量使用Haake公司的Viskotester VT 02在25℃+/-1℃下用锭子1实施。在30秒之后读数。
然而,现有技术中的缺点是,传统的乳液在涂覆以后出汗时会使皮肤产生黏糊感。除此之外,出汗很多的时候(例如当所述乳液涉及盛夏时使用的防晒剂),在皮肤上形成白色的条纹。因此,使得防晒剂不能均匀分布;皮肤各个局部受到的日光照射防护不均匀。
因此,本发明的任务是,开发出一种不具有现有技术中缺点的乳液。
发明内容
令人惊奇地,本发明的任务通过包含下列物质的组合的化妆乳状液得以实现:
a)0.5至3重量%的硬脂酸甘油酯SE,
b)1至5重量%的十六/十八醇,
c)0.01至0.5重量%的PEG-40蓖麻油,
d)0.05至0.25重量%的十六/十八烷基硫酸钠,
e)0.5至3重量%的肉豆蔻酸十四烷基酯,
分别基于制剂的总重量。
本发明的制剂令人惊奇地很快渗入皮肤。
除此之外,令人惊奇的是,所述制剂尤其很少“变白”。根据本发明,“变白”作用理解为一种现象,该现象例如在“Sensory EvaluationTechniques,3rd Edition,Meilgaard,Civille,Carr,CRC Press BocaRaton,London,New York,Washington,D.C.,184-185页(“Terms usedto describe skinfeel of lotions and creams)”中被描述,并且可以简单地用感官上的一组对象试验来证实。在此将0.1ml产品分配在前臂上侧的限定表面上。在此过程中评价,在其消失之前产品在多大程度上呈现白色,持续多长时间。按照10级标度来分级,其中0=不变白/和10=强变白。
硬脂酸甘油酯SE(INCI硬脂酸甘油酯SE)涉及甘油与硬脂酸的化合物(单硬脂酸甘油酯)以及一部分硬脂酸钠和/或硬脂酸钾,可购自Goldschmidt公司,商品名为TEGIN(CTFA名称:硬脂酸甘油酯SE,CAS-Nr 11099-07-3(甘油单硬脂酸酯(Glycerinmonodistearat)/棕榈酸酯)和593-29-3(硬脂酸钾/棕榈酸钾))。
根据本发明有利的是,本发明的制剂包含一种或多种UV光防护过滤剂作为进一步的组分。
本发明有利的实施方案的特征在于,所述制剂包含一种或多种UV光防护过滤剂,其选自下列化合物:亚苯基-1,4-二-(2-苯并咪唑基)-3,3’-5,5’-四磺酸盐、2-苯基苯并咪唑-5-磺酸盐、1,4-二(2-氧代-10-磺基-3-亚冰片基甲基)-苯及其盐、4-(2-氧代-3-亚冰片基甲基)苯磺酸盐、2-甲基-5-(2-氧代-3-亚冰片基甲基)磺酸盐、2,2’-亚甲基-二-(6-(2H-苯并三唑-2-基)-4-(1,1,3,3-四甲基丁基)-苯酚)、2-(2H-苯并三唑-2-基)-4-甲基-6-[2-甲基-3-[1,3,3,3-四甲基-1-[(三甲基甲硅烷基)氧基]二硅氧烷基]丙基]-苯酚、3-(4-甲基苯亚甲基)樟脑(campher)、3-苯亚甲基樟脑、乙基己基水杨酸酯、对苯二亚甲基二樟脑磺酸、4-(二甲基氨基)-苯甲酸(2-乙基己基)酯、4-(二甲基氨基)苯甲酸戊基酯、4-甲氧基苯亚甲基丙二酸二(2-乙基己基)酯、4-甲氧基肉桂酸(2-乙基己基)酯、4-甲氧基肉桂酸异戊基酯、2-羟基-4-甲氧基苯甲酮、2-羟基-4-甲氧基-4’-甲基苯甲酮、2,2’-二羟基-4-甲氧基苯甲酮、2-(4’-二乙基氨基-2’-羟基苯甲酰)-苯甲酸己基酯、4-叔丁基-4’-甲氧基二苯甲酰甲烷、水杨酸高酯、2-乙基己基-2-羟基苯甲酸酯、2-乙基己基-2-氰基-3,3-二苯基丙烯酸酯、二甲基共二乙基苯亚甲基丙二酸酯(Dimethicodiethylbenzalmalonat)、3-(4-(2,2-二乙氧基羰基乙烯基)-苯氧基)丙烯基)-甲氧基硅氧烷/二甲基硅氧烷共聚物、2,4-二-{[4-(2-乙基-己氧基)-2-羟基]-苯基}-6-(4-甲氧基苯基)-1,3,5-三嗪(INCI:二-乙基己氧基苯酚甲氧基苯基三嗪)、二辛基丁基酰氨基三嗪酮(INCI:二乙基己基-丁酰氨基三嗪酮)、2,4-二-[5-1(二甲基丙基)苯并噁唑-2-基-(4-苯基)-亚氨基]-6-(2-乙基己基)-亚氨基-1,3,5-三嗪(CAS Nr.288254-16-0)、4,4’,4”-(1,3,5-三嗪-2,4,6-三基三亚氨基)-三苯甲酸-三(2-乙基己基酯)(即:2,4,6-三-[苯胺基-(对羰-2’-乙基-1’-己氧基)]-1,3,5-三嗪(INCI:乙基己基三嗪酮)、2,4,6-三联苯-4-基-1,3,5-三嗪、辛基5-N,N-二乙基氨基-2-苯基磺酰-2,4-戊二烯酸酯,如WO 2006/125676和WO2004/006878中描述的部花青、苯甲酰肉桂腈、二氧化钛、氧化锌,所述UV光防护过滤剂的浓度为0.01至40重量%,基于制剂的总重量。
根据本发明优选的是,所述制剂包含一种或多种UV光防护过滤剂,其选自二氧化钛、4,4’,4”-(1,3,5-三嗪-2,4,6-三基三亚氨基)-三苯甲酸-三(2-乙基己基酯)、4-甲氧基肉桂酸(2-乙基己基)酯、4-叔丁基-4’-甲氧基-二苯甲酰甲烷、2-苯基苯并咪唑-5-磺酸盐、2,4-二-{[4-(2-乙基-己氧基)-2-羟基]-苯基}-6-(4-甲氧基苯基)-1,3,5-三嗪,其中根据本发明尤其优选所有这些过滤剂的组合。
根据本发明,当本发明的制剂不含对甲基苯亚甲基樟脑是有利的。
按照本发明,颜料(二氧化钛、氧化锌)也可以有利地以市售的油状或水状预分散体形式使用。这种预分散体可以有利地已加入了分散助剂和/或增溶剂。
根据本发明,颜料(二氧化钛、氧化锌)可以有利地已被表面处理(“被涂覆”),其中例如应该形成或保持亲水的、两性的或疏水的特性。这种表面处理可以是,将颜料根据已知的方法施加薄的亲水和/或疏水的无机和/或有机的层。按照本发明,不同的表面涂层还可以包含水。
按照本发明,无机表面涂层可以由氧化铝(Al2O3)、氢氧化铝Al(OH)3,或者水合氧化铝(即:矾土,CAS-Nr.:1333-84-2)、六偏磷酸钠(NaPO3)6、偏磷酸钠(NaPO3)n、二氧化硅(SiO2)(即:硅石,CAS-Nr.:7631-86-9)、硫酸钡(BaSO4)或氧化铁(Fe2O3)组成。这些无机表面涂层可以单独存在,组合存在和/或与有机涂层材料组合存在。
按照本发明,有机表面涂层可以由植物或动物硬脂酸铝、植物或动物硬脂酸、月桂酸、二甲基聚硅氧烷(即Dimethicone)、甲基聚硅氧烷(Methicone)、二甲基硅油(平均链长为200至350个二甲基硅氧烷单元的二甲基聚硅氧烷和硅胶的混合物)或者藻酸。这些有机表面涂层可以单独存在,组合存在和/或与无机涂层材料组合存在。
本发明优选的实施方案的特征在于,所述制剂包含基于制剂总重量而言浓度为0.1至5重量%的二氧化钛作为UV过滤剂。
根据本发明尤其优选的是,所述制剂包含基于制剂总重量而言浓度为0至5重量%的二氧化钛作为UV过滤剂。
根据本发明,本发明有利的实施方案的特征在于,本发明的制剂包含一种或多种选自下述的化合物:对羟基苯甲酸酯、苯氧基乙醇、乙基己基甘油、2-甲基丙-1,3-二醇、丁二醇、丙二醇,基于制剂总重量计其可以以0.01至10重量%的总浓度存在。
根据本发明,本发明有利的实施方案的特征在于,所述制剂包含基于制剂总重量计最高为5重量%的甘油。本发明优选甘油的含量为0.1至2重量%,基于制剂的总重量计。
根据本发明,本发明有利的实施方案的特征在于,所述制剂包含基于制剂总重量计最高为15重量%的乙醇。本发明尤其优选的是,乙醇的含量为4至10重量%,基于制剂的总重量计。
根据本发明,本发明有利的实施方案的特征在于,所述制剂包含基于制剂总重量计最高为5重量%的淀粉衍生物。本发明优选的是,淀粉衍生物的含量为1至4重量%,基于制剂的总重量计。
根据本发明有利的是,所述淀粉衍生物选自下列化合物:磷酸双淀粉、辛烯基琥珀酸淀粉钠。根据本发明尤其优选两种淀粉衍生物的组合。
根据本发明有利的是,本发明的制剂包含黄原胶。本发明优选的是,黄原胶的含量为0.1至0.5重量%,基于制剂的总重量计。
根据本发明有利的是,本发明的制剂包含醋酸维生素E。本发明优选以基于制剂的总重量计0.01至1重量%的浓度来使用这种化合物。
根据本发明有利的是,本发明的制剂包含一种或多种选自下列化合物组的油组分:C12-15烷基苯甲酸酯、三(辛酸/癸酸)甘油酯、碳酸二辛酯。
在此证实本发明尤其优选的是,所述油组分以下列使用浓度(基于制剂的总重量)来使用:
C12-15烷基苯甲酸酯:4至8重量%,
三(辛酸/癸酸)甘油酯:0.5至5重量%。
根据本发明有利的是,本发明的制剂包含一种或多种选自下述的化合物作为进一步的内含物:叶酸,八氢番茄红素(Phytoen),D-生物素,辅酶Q10,α-葡糖基芸香苷(α-Glucosylrutin),肉毒碱,聚多卡醇(Polydocanol),天然和/或合成的异类黄酮,尤其着色剂木黄酮,类黄酮,类胡萝卜素,肌酸,肌酸酐,牛磺酸,抗坏血酸+衍生物氧,二羟基丙酮;8-十六烯-1,16-二羧酸,甘油基葡萄糖,长链以及短链透明质酸(即平均分子量为1百万至3百万道尔顿,以及5000道尔顿至1百万道尔顿的透明质酸)和/或甘草查尔酮A(Licochalcon A)。所述制剂中包含的这类内含物的单个浓度可以分别为0.01至10重量%,基于制剂的总重量计。
根据本发明有利的是,本发明的制剂另外包含脲,浓度为0.01至50重量%,优选浓度为0.1至20重量%,尤其优选浓度为1至15重量%,基于制剂的总重量计。
此外有利的是,本发明的制剂还可以包含用于防蚊子、扁虱和蜘蛛等的驱虫剂。有利的是例如N,N-二乙基-3-甲基苯甲酰胺(商品名:“DEET”),邻苯二甲酸二甲酯(商品名:Palatinol M,DMP),1-哌啶羧酸-2-(2-羟乙基)-1-甲基丙基酯和尤其是3-(N-正丁基-N-乙酰基-氨基)-丙酸乙基酯(可从Merck公司以商品名Insekt 得到)。所述驱虫剂既可以单独使用也可以组合使用。
本发明制剂的水相可以有利地包含常见的化妆助剂,例如醇,尤其是那些C数较低的醇,优选乙醇和/或异丙醇,较低C数的二元醇或者多元醇和它们的醚,优选丙二醇,2-甲基丙-1,3-二醇,乙二醇,乙二醇单乙醚或乙二醇单丁醚,丙二醇单甲醚,丙二醇单乙醚或丙二醇单丁醚,二甘醇单甲醚或二甘醇单乙醚和类似产物,聚合物,泡沫稳定剂,电解质,和尤其一种或多种增稠剂,其可以有利地选自二氧化硅,硅酸铝,多糖和/或它们的衍生物,例如透明质酸,黄原胶,角叉菜胶,羟基丙基甲基纤维素,尤其有利地选自聚丙烯酸酯,优选选自所谓卡巴普(Carbopole)的聚丙烯酸酯,例如980、981、1382、2984、5984类型的卡巴普,其可以单独或组合使用。其它本发明有利的增稠剂是INCI名称为丙烯酸酯/C10-30烷基丙烯酸酯交联聚合物(例如NOVEON公司的Pemulen TR 1,Pemulen TR 2,Carbopol 1328)的那些和Aristoflex AVC(INCI:丙烯酰二甲基牛磺酸铵/VP共聚物)。
根据本发明有利的是,本发明的制剂包含成膜剂。本发明意义上的成膜剂是通过下列特性表征的不同组成的物质:将成膜剂溶解在水或其它适当的溶剂中,然后将所述溶液涂覆在皮肤上,则在溶剂蒸发之后形成膜,它基本上起到将光过滤剂固定在皮肤上并且提高产品的防水性能的作用。
尤其有利的是,所述成膜剂选自基于聚乙烯吡咯烷酮(PVP)
的聚合物。尤其优选聚乙烯吡咯烷酮的共聚物,例如PVP十六烯共聚物和PVP二十烯共聚物,它们可以从GAF化学公司以商品名AntaronV216和Antaron V220得到。
同样有利的是其它聚合的成膜剂,例如从National Starch andChemical公司以商品名Flexan 130得到的聚苯乙烯磺酸钠,和/或从Rewo以商品名Rewopal PIB1000得到的聚异丁烯。其它适合的聚合物是例如聚丙烯酰胺(Seppigel 305),聚乙烯醇,PVP,PVP/VA共聚物,聚乙二醇,丙烯酸酯/辛基丙烯酰胺共聚物(Dermacryl 79)。同样有利的是应用氢化蓖麻油二聚双亚油酸酯(CAS 646054-62-8,INCI氢化蓖麻油二聚双亚油酸酯),可以从Kokyu Alcohol Kogyo公司以RisocastDA-H的商品名得到,或者还有可以从Croda Chemicals公司以商品名Crodamol STS得到的PPG-3苄基醚肉豆蔻酸酯(CAS 403517-45-3)。
此外,如果使用抗氧化剂作为添加剂或有效物质,可得到尤其有利的制剂。根据本发明所述制剂有利地包含一种或多种抗氧化剂。作为有利但是任选使用的抗氧化剂可以使用所有适合化妆用途或常用的抗氧化剂。
按照本发明尤其有利的是可以使用水溶性抗氧化剂,如维生素,例如抗坏血酸及其衍生物。
所述抗氧化剂(一种或多种化合物)在制剂中的量优选为0.001至30重量%,尤其优选0.05至20重量%,特别是0.1至10重量%,基于制剂的总重量计。
有利的是维生素A和/或维生素A衍生物和/或胡萝卜素和/或其衍生物作为一种或多种抗氧化剂,它们分别的浓度选择为0.001至10重量%,基于配方的总重量计。
尤其有利的是,根据本发明的化妆制剂包含化妆有效物质,其中优选的有效物质是抗氧化剂,其可以保护皮肤防止氧化损耗。
根据本发明的配方,其例如包含已知的抗皱有效物质如黄酮苷(flavonglycoside)(尤其α-糖基芸香苷(α-Glycosylrutin)),辅酶Q10,视黄醇和酯,维生素E和/或衍生物等,尤其有利地适合用于防止美学上不吸引人的皮肤改变,例如在皮肤老化时出现的(例如干燥,粗糙,和干燥细纹的形成,搔痒,减少的回油(Rueckfettung)(例如在清洗之后),可见的血管扩张(毛细管扩张,Cuperosis),松弛以及皱纹和细纹的形成,局部的色素沉着过度、色素沉着过低和不当的色素沉着(例如老年斑),对机械应力的缺乏抵抗性增大(例如皲裂)等)以及疲劳的皮肤。另外它们有利地适合对抗干燥和/或粗糙的皮肤外观的形成。
根据本发明的化妆制剂可以包含化妆助剂,例如在这类制剂中常用的那些,例如防腐剂,防腐助剂,络合剂,杀菌剂,香料,用于抑制或增加泡沫的物质,着色物质,具有着色作用的颜料,增稠剂,润湿和/或保湿物质,改善皮肤感觉的填充剂,脂肪,油,蜡或其它化妆或皮肤病学配方常见的组分如醇、多元醇,聚合物,泡沫稳定剂,电解质,有机溶剂或硅氧烷衍生物。
根据本发明,本发明的制剂尤其用作防晒剂。
附图说明
图1显示了作为本发明产品的样品1在涂抹到试验对象身体上、并进行桑拿而明显出汗后的涂抹部位外观照片。
图2显示了非本发明产品的样品2(市售防晒乳液)在涂抹到试验对象身体上、并进行桑拿而明显出汗后的涂抹部位外观照片。
图3显示了各试验对象在涂抹样品1和样品2并进行桑拿而明显出汗之前、桑拿期间和桑拿之后的问卷调查感受评分结果。
具体实施方式
对比试验
试验设计:
·分别用一种产品单独涂抹身体一半
样品1-根据本发明的产品
样品2-非根据本发明的产品
·让产品渗入15分钟
·进行桑拿直至试验对象(n=6)明显出汗(最长30分钟)
·视觉评价出汗情况(照片记录)并且询问试验对象的个人感受
配方
样品1:
硬脂酸甘油酯SE | 1 |
十六/十八醇 | 1,9 |
PEG-40蓖麻油 | 0,375 |
十六/十八烷基硫酸钠 | 0,19 |
十六醇 | 1,5 |
肉豆蔻酸十四烷基酯 | 1,0 |
黄原胶 | 0,4 |
C12-15烷基苯甲酸酯 | 5,5 |
磷酸双淀粉 | 3 |
辛烯基琥珀酸淀粉钠 | 1,5 |
甘油 | 0,75 |
变性乙醇 | 8 |
二氧化钛 | 0,5 |
乙基己基甲氧基肉桂酸酯 | 9,5 |
丁基甲氧基二苯甲酰甲烷 | 4,5 |
苯基苯并咪唑磺酸 | 2,0 |
二乙基己氧基苯酚甲氧基苯基三嗪 | 3,0 |
醋酸维生素E | 0,1 |
Na2H2EDTA | 0,2 |
香料,防腐剂 | 适量 |
着色剂等 | 适量 |
柠檬酸,柠檬酸钠 | 适量 |
氢氧化钠 | 适量 |
水 | 加至100,0 |
样品2
市售的防晒乳液
测量:
·视觉评价出汗
·问卷调查的个体感受
-评价测试问题(进行桑拿之前)
-评价测试问题(进行桑拿期间)
-结束桑拿过程(15至30分钟)
-评价测试问题(进行桑拿之后)
·测定涂抹的产品量(没有差别,数据未显示)
结果:
·视觉评价出汗
图1和图2分别显示了涂抹本发明的样品(样品1)以及市售的防晒乳液(样品2)的受试者的视觉评价结果。
·问卷调查的个体感受
图3显示了涂抹本发明的样品(样品1)以及市售的防晒乳液(样品2)的受试者的问卷调查个体感受结果。
实施例
下面的实施例只是用于说明本发明,而不构成对本发明的限制。只要没有另外提及,所有量、比例和百分比均基于所述制剂的重量、总量和/或总重量。
1 | 2 | 3 | 4 | 5 | 6 | |
硬脂酸甘油酯SE | 1 | 1 | 2 | 3 | 1 | 2 |
十六/十八醇 | 1,9 | 2,0 | 1,35 | 2,5 | 2,0 | 1,35 |
PEG-40蓖麻油 | 0,375 | 0,4 | 0,225 | 0,3 | 0,4 | 0,225 |
十六/十八烷基硫酸钠 | 0,19 | 0,18 | 0,11 | 0,3 | 0,18 | 0,11 |
十六醇 | 2,2 | 2 | 1,8 | 3,2 | 2 | 1,8 |
肉豆蔻酸十四烷酯 | 1,5 | 3 | 2 | 1 | 0,5 | 1,5 |
黄原胶 | 0,2 | 0,3 | 0,4 | 0,1 | ||
C12-15烷基苯甲酸酯 | 6 | 5 | 7 | 4 | ||
2-苯基乙基苯甲酸酯 | 1 | 2 | ||||
三(辛酸/癸酸)甘油酯 | 1 | 2 | 2,5 | 2,5 | 2,5 | |
水杨酸十三烷基酯 | 1 | 1 | ||||
磷酸双淀粉 | 3 | 2 | 2,5 | 2,5 | 2 | 2,5 |
辛烯基琥珀酸淀粉钠 | 1,5 | 1 | 2 | 2 | 3 | |
环聚二甲基硅氧烷 | 2 | 2 | 1 | |||
二甲基聚硅氧烷 | 1 | 2 | ||||
PVP十六烯共聚物 | 1 | 1 | 1 | |||
甘油 | 0,9 | 1 | 1,5 | 1,5 | 3 | 1,5 |
变性乙醇 | 7 | 8 | 6 | 6 | 10 | 7 |
二氧化钛 | 0,75 | 0,25 | 0,5 | 1 | ||
部花青 | 1 | |||||
乙基己基三嗪 | 0,75 | 0,5 | 0,25 | 2 | ||
辛基十二烷醇 | 2 | 5,5 | ||||
乙基己基甲氧基肉桂酸酯 | 5 | 3 | 1 | 0,5 | 4,5 | 1 |
丁基甲氧基二苯甲酰甲烷 | 3,4 | 2,0 | 1 | 4,5 | 4,5 | 2 |
奥克利林辛雌酚(Octocrylen) | 9 | 5 | 7,5 | |||
苯基苯并咪唑磺酸 | 1,5 | 1 | 0,5 | |||
甲基丙二醇 | 3 | 2 | ||||
乙基己基水杨酸酯 | 4,5 | |||||
二乙基己氧基苯酚甲氧基苯基三嗪 | 1,7 | 1 | 2,5 | 3 | 3,5 | |
辛基5-N、N-二乙基氨基-2-苯基-磺酰-2,4-戊二烯酸酯 | 1 | 2 | ||||
二乙基己基丁酰氨基三嗪酮 | 1 | |||||
醋酸维生素E | 0,1 | 0,3 | 0,1 | 0,3 | 0,1 | |
Na2H2EDTA | 0,2 | 0,2 | 0,5 | 0,2 | 0,5 | 0,2 |
香料,防腐剂 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
着色剂等 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
柠檬酸,柠檬酸钠 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
氢氧化钠 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
水 | 加至100,0 | 加至100,0 | 加至100,0 | 加至100,0 | 加至100,0 | 加至100,0 |
7 | 8 | 9 | 10 | 11 | |
二乙基己氧基苯酚甲氧基苯基三嗪 | 2,5 | 2 | 4 | 0,8 | |
丁基甲氧基二苯甲酰甲烷 | 0,3 | 4,5 | 4 | 2,25 | 1,5 |
乙基己基甲氧基肉桂酸酯 | 2 | 9,5 | 5,25 | 3,5 | 1,75 |
乙基己基三嗪酮 | 0,3 | 1 | 0,5 | ||
苯基苯并咪唑磺酸 | 3 | 1,5 | 1 | 0,5 | |
二氧化钛+三甲氧基辛酰硅烷 | 1 | 2 | 0,5 | 0,5 | |
C12-15烷基苯甲酸酯 | 8 | 6,5 | 6,5 | 6,5 | 6,5 |
三(辛酸/癸酸)甘油酯 | 3,5 | 2 | 1 | 5 | 3 |
十六/十八醇 | 2,5 | 3 | 2 | 5 | 20 |
PEG-40蓖麻油 | 2 | 5 | |||
十六/十八烷基硫酸钠 | 0,2 | 0,15 | 0,13 | 0,1 | 0,12 |
十六醇 | 1,5 | 2,2 | 2 | 1,5 | 2 |
变性乙醇 | 8 | 6 | 5 | 3 | 10 |
香料 | 0,3 | 0,3 | 0,3 | 0,3 | 0,3 |
甘油 | 3 | 2 | 0,9 | 1 | 2 |
硬脂酸甘油酯SE | 1 | 0,65 | 0,65 | 0,65 | 0,65 |
对羟基苯甲酸甲酯 | 0,3 | 0,3 | 0,3 | 0,3 | |
肉豆蔻酸十四烷基酯 | 1,5 | 1,5 | 1,5 | 1,5 | 1,5 |
辛基十二烷醇 | 7,5 | 5,5 | 5,5 | 5,5 | 5,5 |
苯氧基乙醇 | 0,2 | 0,2 | 0,2 | ||
辛烯基琥珀酸淀粉钠 | 1,5 | 1,2 | 1,5 | 1 | 1,5 |
羟基乙脲 | 2 | 5 | |||
磷酸双淀粉 | 3,5 | 3 | 4 | 3 | 2,5 |
醋酸维生素E | 0,1 | 0,1 | 0,1 | 0,1 | 0,1 |
Na2H2EDTA | 1 | 1 | 1 | 1 | 1 |
氢氧化钠 | 0,6 | 0,45 | 0,3 | 0,15 | |
黄原胶 | 0,4 | 0,4 | 0,4 | 0,4 | 0,4 |
水 | 加至100,0 | 加至100,0 | 加至100,0 | 加至100,0 | 加至100,0 |
Claims (10)
1.一种包含下列物质的组合的化妆乳状液:
a)0.5至3重量%的硬脂酸甘油酯SE,
b)1至5重量%的十六/十八醇,
c)0.01至0.5重量%的PEG-40蓖麻油,
d)0.05至0.25重量%的十六/十八烷基硫酸钠,以及
e)0.5至3重量%的肉豆蔻酸十四烷基酯,
分别基于制剂的总重量。
2.根据权利要求1的化妆乳状液,其特征在于,所述制剂包含一种或多种UV光防护过滤剂作为进一步的组分。
3.根据前述权利要求任一项的化妆乳状液,其特征在于,所述制剂包含一种或多种UV光防护过滤剂,其选自下列化合物:亚苯基-1,4-二-(2-苯并咪唑基)-3,3’-5,5’-四磺酸盐、2-苯基苯并咪唑-5-磺酸盐、1,4-二(2-氧代-10-磺基-3-亚冰片基甲基)-苯及其盐、4-(2-氧代-3-亚冰片基甲基)苯磺酸盐、2-甲基-5-(2-氧代-3-亚冰片基甲基)磺酸盐、2,2’-亚甲基-二-(6-(2H-苯并三唑-2-基)-4-(1,1,3,3-四甲基丁基)-苯酚)、2-(2H-苯并三唑-2-基)-4-甲基-6-[2-甲基-3-[1,3,3,3-四甲基-1-[(三甲基甲硅烷基)氧基]二硅氧烷基]丙基]-苯酚、3-(4-甲基苯亚甲基)樟脑、3-苯亚甲基樟脑、乙基己基水杨酸酯、对苯二亚甲基二樟脑磺酸、4-(二甲基氨基)-苯甲酸(2-乙基己基)酯、4-(二甲基氨基)苯甲酸戊基酯、4-甲氧基苯亚甲基丙二酸二(2-乙基己基)酯、4-甲氧基肉桂酸(2-乙基己基)酯、4-甲氧基肉桂酸异戊基酯、2-羟基-4-甲氧基苯甲酮、2-羟基-4-甲氧基-4’-甲基苯甲酮、2,2’-二羟基-4-甲氧基苯甲酮、2-(4’-二乙基氨基-2’-羟基苯甲酰)-苯甲酸己基酯、4-叔丁基-4’-甲氧基-二苯甲酰甲烷、水杨酸高酯、2-乙基己基-2-羟基苯甲酸酯、2-乙基己基-2-氰基-3,3-二苯基丙烯酸酯、二甲基共二乙基苯亚甲基丙二酸酯(Dimethicodiethylbenzalmalonat)、3-(4-(2,2-二乙氧基羰基乙烯基)-苯氧基)丙烯基)-甲氧基硅氧烷/二甲基硅氧烷共聚物、2,4-二-{[4-(2-乙基-己氧基)-2-羟基]-苯基}-6-(4-甲氧基苯基)-1,3,5-三嗪(INCI:二-乙基己氧基苯酚甲氧基苯基三嗪)、二辛基丁基酰氨基三嗪酮(INCI:二乙基己基-丁酰氨基三嗪酮)、2,4-二-[5-1(二甲基丙基)苯并噁唑-2-基-(4-苯基)-亚氨基]-6-(2-乙基己基)-亚氨基-1,3,5-三嗪(CAS Nr.288254-16-0)、4,4’,4”-(1,3,5-三嗪-2,4,6-三基三亚氨基)-三苯甲酸-三(2-乙基己基酯)(即:2,4,6-三-[苯胺基-(对羰-2’-乙基-1’-己氧基)]-1,3,5-三嗪(INCI:乙基己基三嗪酮)、2,4,6-三联苯-4-基-1,3,5-三嗪、辛基5-N,N-二乙基氨基-2-苯基磺酰-2,4-戊二烯酸酯、部花青、苯甲酰肉桂腈、二氧化钛、氧化锌,所述UV光防护过滤剂的浓度为0.01至40重量%,基于制剂的总重量。
4.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含一种或多种选自下述的化合物:对羟基苯甲酸酯、苯氧基乙醇、乙基己基甘油、2-甲基丙-1,3-二醇、丁二醇、丙二醇。
5.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含二氧化钛作为UV过滤剂,其浓度为0.1至5重量%,基于制剂总重量。
6.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含甘油,其基于制剂总重量计最高为5重量%。
7.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含乙醇,基于制剂总重量计最高为15重量%。
8.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含淀粉衍生物,其基于制剂总重量计最高为5重量%。
9.根据权利要求8的化妆乳状液,其特征在于,所述淀粉衍生物选自下列化合物:磷酸双淀粉、辛烯基琥珀酸淀粉钠。
10.根据权利要求1或2的化妆乳状液,其特征在于,所述制剂包含一种或多种选自化合物C12-15烷基苯甲酸酯、三辛酸/癸酸甘油酯、碳酸二辛酯中的油组分。
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US6511655B1 (en) * | 1999-08-16 | 2003-01-28 | Beiersdorf Ag | Cosmetic or dermatological preparations of the oil-in-water type |
EP1380288A1 (de) * | 2002-07-10 | 2004-01-14 | Beiersdorf AG | Kosmetische und dermatologische Lichtschutzformulierungen an einem Gehalt an hydrophobisierten Acrylamidomethylpropylsulfonsäure-Polymeren |
DE102004027476A1 (de) * | 2004-06-02 | 2005-12-22 | Beiersdorf Ag | 2-Phenylehtylbenzoat in kosmetischen Öl-in-Wasser-UV-Lichtschutzemulsionen |
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US6511655B1 (en) * | 1999-08-16 | 2003-01-28 | Beiersdorf Ag | Cosmetic or dermatological preparations of the oil-in-water type |
EP1380288A1 (de) * | 2002-07-10 | 2004-01-14 | Beiersdorf AG | Kosmetische und dermatologische Lichtschutzformulierungen an einem Gehalt an hydrophobisierten Acrylamidomethylpropylsulfonsäure-Polymeren |
DE102004027476A1 (de) * | 2004-06-02 | 2005-12-22 | Beiersdorf Ag | 2-Phenylehtylbenzoat in kosmetischen Öl-in-Wasser-UV-Lichtschutzemulsionen |
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Granted publication date: 20130102 Termination date: 20170411 |