CN101554159A

CN101554159A - Fenpropathrin microemulsion and preparation method thereof

Info

Publication number: CN101554159A
Application number: CNA2008101038284A
Authority: CN
Inventors: 李鹏; 徐万涛; 徐踪跃; 王成; 吴俊玲; 周晨光; 吴家全; 陈义明; 李凤明; 齐正红; 王丹玉; 马学成
Original assignee: BEIJING GREEN AGROSINO BIOENGINEERING TECHNOLOGY Co Ltd
Current assignee: BEIJING GREEN AGROSINO BIOENGINEERING TECHNOLOGY Co Ltd
Priority date: 2008-04-11
Filing date: 2008-04-11
Publication date: 2009-10-14

Abstract

The invention discloses a fenpropathrin microemulsion and a preparation method thereof. The fenpropathrin microemulsion which can kill pests and mites takes fenpropathrin as the active principle and is characterized that water is used as solvent and synergistic agent also can be added to enhance the pesticide effect. The invention has the characteristics of reduced toxicity and cost, high prevention effect, little pollution, and the like, and can replace corresponding emulsifiable concentrate preparation for preventing and treating pests and mites.

Description

A kind of fenpropathrin microemulsion and preparation method thereof

Technical field

The present invention relates to a kind of desinsection, miticide farm chemical novel form, relate to a kind of fenpropathrin microemulsion and preparation method thereof specifically.

Background technology

A kind of fenpropathrin microemulsion and preparation method thereof.

Chemical name: (R, S)-2-cyano group-3-phenoxy benzyl-2,2,3, the 3-4-methyl cyclopropane carboxylic acid ester.

English name: fenpropthrin

Molecular formula: C ₂₂H ₂₃NO ₃

Structural formula:

A kind of pyrethroid insecticidal/acaricidal agent, have tag, stomach toxicity and repellent action, do not inhale in not having, fumigation action, can kill larva, adult and ovum, effective to multiple mite class, the moderate lasting period is arranged in the field, low warm purgative effect is better.Put the initial stage on market at it, promptly with efficient, low toxicity, dosage is few and account for rapidly in agricultural chemicals market, so that the gesture that superseded organophosphorous pesticide is arranged greatly, but growth along with the operating period, very fast its not good to mite class preventive effect and the insect pest resistance increases sharply weakness that exposed, even some original situation of selling well district become the resistance district, loses use value.In order to delay the generation of insect to the resistance of certain class agricultural chemicals, increase the service life, keep drug effect, aspect pesticidal preparations, done many-sided research both at home and abroad.The fenpropathrin product of selling on the market is mainly the missible oil formulation, consumption of organic solvent is big, is unfavorable for reducing production costs and reducing environmental pollution, and this finished product is produced in addition and the storing poor stability, the opening up of soup, wetting, permeance property is not good, its formulation does not meet the requirement of agricultural chemicals development trend.Up to the present, do not see the report of fenpropathrin microemulsion patent as yet.

Microemulsion (ME) is one of novel form that meets the agricultural chemicals developing direction, is made up of water, water-insoluble and water-soluble substance, and former medicine is with the microparticulate preparation wherein of 0.01-0.1u.It is a stable homogeneous phase on the thermodynamics, the solubility system.Outward appearance is transparence, and microcosmic is to be the limiting condition that aqueous emulsion fully disperses for the big micellar dispersion that expands.Its physics, chemical stability are good, and is strong to plant and insect tissue cell permeability, the absorption ratio height, and preventive effect is good, simultaneously, has production, storing and safe in utilization, environmental pollution is little, helps the improvement of ecotope.

Summary of the invention:

Purpose of the present invention is exactly to disclose a kind of fenpropathrin microemulsion and preparation method thereof.

Another object of the present invention is to overcome the shortcoming of fenpropathrin milk oil preparation, and the prescription and the production method of a kind of efficient, low public hazards, low-cost fenpropathrin microemulsion is provided.

Microemulsion is a kind of pesticides new formulation newly developed in recent years, and this formulation agricultural chemicals is to be solvent with water, uses no or little organic solvent, has both had the outward appearance and the flowability of missible oil class agricultural chemicals, has avoided many shortcomings of missible oil formulation again, is the formulations of pesticide of advocating development.Auxiliary agent content height in this formulation agricultural chemicals, the opening up of soup, wetting, good penetrability, emulsified particles is thin, and drug effect is better than missible oil class preparation, is the preferred dosage form to stable, the efficient low content agricultural chemicals of water.

The fenpropathrin that the present invention selects for use meets the various conditions that prepare microemulsion.Prepared microemulsion is compared with the missible oil with equal size, and its production cost can reduce 2000-3000 unit/ton, and product toxicity and less to the pollution of environment is produced and the storing safety improves.

The present invention is achieved in that the former medicinal cosolvent dissolving of fenpropathrin, adds stabilizing agent, emulsifier and builder successively, by homogenize technology it is scattered in the water, and each the composition weight percentage composition of fenpropathrin microemulsion that forms appearance transparent is as follows:

Fenpropathrin 1-20%

Cosolvent 5-30%

Builder 0-20%

Emulsifier 5-25%

Stabilizing agent 1-10%

Water surplus

In order to illustrate further purpose of the present invention, provide the suitableeest weight percentage of this microemulsion below:

Fenpropathrin 2-10%

Cosolvent 5-10%

Builder 0.5-5%

Stabilizing agent 0.5-5%

Emulsifier 5-20%

Water surplus

Described cosolvent is low carbon fat alcohol (as methyl alcohol, ethanol, a butanols etc.), one or more in aromatic solvent (as benzene,toluene,xylene etc.), acetone, cyclohexanone, the dimethyl formamide.

Described builder is one or more in fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene, azone, thiophene ketone, Tea Saponin, Butacide, Octachlorodipropyl Ether, the synergy phosphorus.

Described emulsifier is the emulsifier that non-ionic monomer and agricultural chemicals 500# form, and wherein non-ionic monomer can be one or more composition.

Described stabilizing agent is one or more in ethylene glycol, polyethylene glycol, polyvinyl alcohol, urea, glycerine, benzoate, the xanthans.

Described water is from water, deionized water, underground water, the distilled water one or more.

Provided the specific embodiment of microemulsion of the present invention below:

Example 1:

2.5% fenpropathrin microemulsion

Fenpropathrin 2.5%;

Dimethylbenzene 3%;

TX-10 3％；

2201 15％；

Butanols 3%;

Ethylene glycol 4%;

The deionized water surplus.

Example 2:

5% fenpropathrin microemulsion

Fenpropathrin 5%;

Cyclohexanone 5%;

JFC 3％；

QK-7 emulsifier 15%;

Azone 2%;

Urea 4%;

The running water surplus.

Example 3:

10% fenpropathrin microemulsion

Fenpropathrin 10%;

Toluene 8%;

Methyl alcohol 5%;

Butanols 3%;

TX-10 5％；

34# 13％；

Sodium Benzoate 0.5%;

Ethylene glycol 4%;

Thiophene ketone 1%;

Tea Saponin 4%;

The deionized water surplus.

Example 4:

15% fenpropathrin microemulsion

Fenpropathrin 15%;

Cyclohexanone 12%;

TX-10 3％；

601 15％％；

Butanols 3%;

Butacide 2%;

Glycerine 4%;

The running water surplus.

Claims

1. fenpropathrin microemulsion and preparation method thereof is characterized in that fenpropathrin (active component) is dispersed in the transparent or semitransparent microemulsion of formation in the water under promoter effect, and each weight percentages of components is:

Fenpropathrin 1-20%;

Cosolvent 5-30%;

Builder 0-20%;

Emulsifier 5-25%;

Stabilizing agent 1-10%;

Water surplus.

2. fenpropathrin microemulsion is characterized in that each weight percentages of components is:

Fenpropathrin 2-10%;

Cosolvent 5-10%;

Builder 0.5-5%;

Stabilizing agent 0.5-5%;

Emulsifier 5-20%;

Water surplus.

3. fenpropathrin microemulsion as claimed in claim 1, it is characterized in that cosolvent is low carbon fat alcohol (as methyl alcohol, ethanol, a butanols etc.), one or more in aromatic solvent (as benzene,toluene,xylene etc.), acetone, cyclohexanone, the dimethyl formamide.

4. fenpropathrin microemulsion as claimed in claim 1 is characterized in that described builder is one or more in fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene, azone, thiophene ketone, Tea Saponin, Butacide, Octachlorodipropyl Ether, the synergy phosphorus.

5. fenpropathrin microemulsion as claimed in claim 1 is characterized in that described emulsifier is the emulsifier that non-ionic monomer and agricultural chemicals 500# form, and wherein non-ionic monomer can be one or more composition.

6. fenpropathrin microemulsion as claimed in claim 1 is characterized in that described stabilizing agent is one or more in ethylene glycol, polyethylene glycol, polyvinyl alcohol, urea, glycerine, benzoate, the xanthans.

7. fenpropathrin microemulsion as claimed in claim 1 is characterized in that described water is for from water, deionized water, underground water, the distilled water one or more.