CN101548152B - Contact lens blister packages and methods for automated inspection of hydrated contact lenses - Google Patents

Contact lens blister packages and methods for automated inspection of hydrated contact lenses Download PDF

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Publication number
CN101548152B
CN101548152B CN2007800451911A CN200780045191A CN101548152B CN 101548152 B CN101548152 B CN 101548152B CN 2007800451911 A CN2007800451911 A CN 2007800451911A CN 200780045191 A CN200780045191 A CN 200780045191A CN 101548152 B CN101548152 B CN 101548152B
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China
Prior art keywords
packing
chamber
contact lenses
contact lens
substrate parts
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CN2007800451911A
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CN101548152A (en
Inventor
朱莉·克莱门特
史蒂夫·霍普
凯文·奥尔德里奇
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Cooper optics International Ltd.
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CooperVision International Holding Co LP
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/326Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming one compartment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/22Boxes or like containers with side walls of substantial depth for enclosing contents
    • B65D1/26Thin-walled containers, e.g. formed by deep-drawing operations
    • B65D1/30Groups of containers joined together end-to-end or side-by-side
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/30Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure
    • B65D85/38Containers, packaging elements or packages, specially adapted for particular articles or materials for articles particularly sensitive to damage by shock or pressure for delicate optical, measuring, calculating or control apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00Measuring arrangements characterised by the use of optical techniques
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M11/00Testing of optical apparatus; Testing structures by optical methods not otherwise provided for
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M11/00Testing of optical apparatus; Testing structures by optical methods not otherwise provided for
    • G01M11/02Testing optical properties
    • G01M11/0207Details of measuring devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M11/00Testing of optical apparatus; Testing structures by optical methods not otherwise provided for
    • G01M11/02Testing optical properties
    • G01M11/0207Details of measuring devices
    • G01M11/0214Details of devices holding the object to be tested
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M11/00Testing of optical apparatus; Testing structures by optical methods not otherwise provided for
    • G01M11/02Testing optical properties
    • G01M11/0242Testing optical properties by measuring geometrical properties or aberrations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2585/00Containers, packaging elements or packages specially adapted for particular articles or materials
    • B65D2585/54Containers, packaging elements or packages specially adapted for particular articles or materials for articles of special shape not otherwise provided for
    • B65D2585/545Contact lenses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/95Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
    • G01N21/958Inspecting transparent materials or objects, e.g. windscreens
    • G01N2021/9583Lenses

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Geometry (AREA)
  • Ceramic Engineering (AREA)
  • Packages (AREA)
  • Eyeglasses (AREA)
  • Packaging Frangible Articles (AREA)

Abstract

A contact lens package includes a base member including a cavity dimensioned to accommodate contact lens and a liquid therein. The combination of the cavity, the contact lens, and the liquid cooperate to collimate partially collimated light directed toward a bottom surface of the cavity. The cavity can be sealed by attaching a removable sealing member to the base member around the cavity. Methods of inspecting ophthalmic lenses using the present packages are also described.

Description

Contact lens blister packages and be used for the method for the moisture contact lenses of self-verifying
Technical field
Embodiment described herein relates to contact lens blister packages and uses described blister package to check the method for moisture contact lenses.
Background technology
The manufacturing of ophthalmic lens (for example contact lenses) also comprises except that others checks whether eyeglass has flaw and described eyeglass is packaged in the packing.In a large amount of ophthalmic lens (for example contact lenses) were produced, also expectation continued the new manufacturing assembly of exploitation, system, method or the like to reduce the production time, to reduce production costs and boost productivity except that others.
Summary of the invention
A kind of contact lens blister packages, or a kind of thermoplastic base member that is used for contact lens blister packages comprises through determining that size reaches from the outward extending flange in described chamber with the chamber that holds moisture contact lenses.When described packing or substrate parts were used for the moisture contact lenses of during lens inspection procedure fixing, described chamber can be regarded as light collimation cavity.The method of checking contact lenses comprises described blister package of use or described thermoplastic base member.
Description of drawings
Fig. 1 is the skeleton view through the sealing array of contact lens packages.
Fig. 2 is array single through seal-packed skeleton view of Fig. 1.
Fig. 3 is the skeleton view of packing that wherein partly removes Fig. 2 of described seal member.
Fig. 4 is the skeleton view of array of unsealed contact lens packages.
Fig. 5 is the plan view from above of a unsealed contact lens packages.
Fig. 6 is the sectional view of packing of Fig. 5 of 6-6 along the line.
Fig. 7 is the sectional view of packing of Fig. 5 of 7-7 along the line.
Fig. 8 is the side plan view of the packing of Fig. 5.
Fig. 9 is the diagram of a part that comprises the ophthalmic lens check system of the present invention packing.
Figure 10 is the diagram of the part of ophthalmic lens check system, is wherein collimated by the diapire of described cavity package, described ophthalmic lens and the liquid that is present in the described chamber through the light of part collimation.
Figure 11 is the side plan view of another contact lens package.
Embodiment
With reference to Fig. 1, graphic extension has the array 70 of a plurality of contact lens packages 10.Illustrated array 70 is made up of four contact lens packages 10.Another array can be made up of two contact lens packages.Another array can be made up of three contact lens packages.Another array can be made up of five contact lens packages.Additional arrays of packages can comprise five above contact lens packages.
In array 70, contact lens package 10 is close at least one other contact lens package 10 and locatees.For instance, contiguous contact lens package 10b of contact lens package 10a.In addition, contiguous separately two contact lens packages of contact lens package 10b and contact lens package 10c.The only contiguous contact lens package 10c of contact lens package 10d.
Packing 10 of the present invention is configured to contain contact lenses.The example that is suitable for the contact lenses of the present invention's packing is a hydrogel contact lens.Described hydrogel contact lens can be silicone hydrogel contact lens or non-silicone hydrogel contact lens.Silicone hydrogel contact lens is the hydrogel contact lens that comprises silicon components.The example that can be packaged in the silicone hydrogel contact lens in the present invention's packing comprises the silicone hydrogel contact lens with following U.S.'s employing title (USAN): lotrafilcon A, lotrafilcon B, balafilcon A, galyfilcon A, senofilcon A and comfilcon A.Non-silicone hydrogel contact lens is the hydrogel contact lens that does not contain silicon components.Except that other, the example bag that can be packaged in the non-silicone hydrogel contact lens in the present invention's packing also contains the hydrogel contact lens with following USAN: omafilcon A, ocufilcon A, ocufilcon B, ocufilcon C, ocufilcon D, ocufilcon E, methafilconA, methafilcon B etc.Some contact lenses that are provided in the contact lenses (silicone hydrogel contact lens or non-silicone hydrogel contact lens) in the present invention's packing comprise one or more softening agents.The example of softening agents comprises the wettable reinforcing agent, and its wettable that strengthens contact lenses is so that contact lenses keep comfortable concerning lens wearer, even when end in a day, for example after wearing about 14 hours of contact lenses continuously.An example of softening agents is a surfactant.Except that other, the example of surfactant also comprises poloxamer (poloxamers) and protects beautiful look bright (poloxamines).Another example of softening agents is phosphoryl choline derivative (PC), for example methyl acrylate phosphocholine (MPC), 2-methyl-prop acyl-oxygen ethyl phosphonic acid choline (HEMA-PC) or the like and combination thereof.An example that comprises the contact lenses of phosphoryl choline derivative can be buied from cruel cypress (CooperVision) by trade name proclear.An example that is present in the contact lenses in the present invention's packing comprises polymkeric substance and phosphoryl choline derivative, and described polymkeric substance comprises the hydroxy acrylic acid methyl esters of some units.In the contact lens package 10 of array of packages 70 each all comprises substrate parts 12 and seal member 14.Individual contact lens packages 10 is hereinafter described.In array 70, each seal member 14 all can be regarded as the assembly of sealant 72.Illustrated sealant 72 is across whole array of contact lens packages 70.Individual packages 10 can be separated along line of weakness 74 and array 70.The position of adjoining near two contact lens packages 10 provides line of weakness 74.Line of weakness 74 can be regarded as the perforation in the sealant 72.In other embodiments, line of weakness 74 can not have perforation through formation, for example by the thinner part of sealant 72 is provided in desired location, for instance, relatively thin continuous strip.
In the illustrated embodiment of Fig. 1, the individual packages 10 of array 70 is attached to each other.For instance, packing 10 can comprise in the described packing attachment portion between the two.Described attachment portion can be the integral component of described array of packages, and perhaps it can be to connect in the packing 10 both or both above additional fasteners.
In the illustrated embodiment of Fig. 1, the substrate parts 12 of a plurality of packings 10 can be coupled and further is coupled by single sealant 72.In other embodiments, packing 10 can only be coupled at substrate parts 12 places and can't help sealant 72 and be coupled, and perhaps packs 10 and can only be coupled by sealant 72 but can't help substrate parts 12 and be coupled.
Graphic extension is through sealing single contact lens package 10 among Fig. 2.Contact lens package 10 comprises substrate parts 12 and is coupled to the seal member 14 of substrate parts 12.Fig. 3 graphic extension wherein partly removes the contact lens package 10 of Fig. 2 of seal member 14.Therefore, be appreciated that seal member 14 is removable seal members.Seal member 14 is coupled to the part of substrate parts 12 so that contact lenses are sealed in the chamber of described substrate parts, as discussed herein.
Seal member 14 and this outer sealing layers 72 can be formed by the various materials that are suitable for wrappage.Suitable material should be able to be attached to described substrate parts a part so that the contact lenses that contained in the described chamber remain in the aseptic condition.For instance, described seal member material should be able to be exposed to conditions for sterilization (for example autoclaving, gamma radiation, ultraviolet radiation etc.) and not damage the character of described seal member.Seal member 14 can comprise one or more material layers, for example paillon foil, plastics and similar material.Seal member 14 also can comprise mark, for example letter, numeral and combination thereof.In the illustrated embodiment of packing of the present invention and array, seal member 14 is heat sealed to substrate parts 12.In other embodiments, can use bonding agent or other suitable coupling mechanism that seal member 14 is coupled to substrate parts 12.Therefore, seal member 14 provides the impervious sealing of fluid and prevent to pollute the described sealing through disinfect contact lense and packing liquid that is contained in annular seal space.
Substrate parts 12 and in addition contact lens package 10 comprise proximal end region 18 and far-end 20.Proximal end region 18 comprise two fingers (for example thumb and forefinger) that can be immobilizated in the people but between grip.For simplicity, proximal end region 18 can be regarded as and comprises thumb grip.As shown in Figure 3, can assign to remove seal member 14 by the close end of peelling off seal member 14 from the proximal part 18 of substrate parts 12.In illustrated embodiment, the people can manually peel off seal member 14 towards the far-end 20 of substrate parts 12 from proximal part 18.
As shown in Figure 3, substrate parts 12 comprises first lateral side regions 22 and relative second lateral side regions 24.First and second lateral side regions 22 and 24 is extended from the far-end 20 of proximal end region 18 towards described substrate parts respectively.First and second lateral side regions 22 and 24 respectively can be parallel to each other, perhaps can diminish gradually, for example by assembling towards far-end 20 or dispersing.Graphic extension has wherein removed the array 70 of the contact lens package 10 of sealant 72 among Fig. 4.For simplicity, only one possesses Ref. No. in the packing 10 of the array 70 of Fig. 4.Other packing 10 that should be understood that illustrated array 70 all has same configuration.Each contact lens package 10 of the array 70 of Fig. 4 includes substrate parts 12.Substrate parts 12 comprises chamber 16.Chamber 16 is between proximal end region 18 and far-end 20.Substrate parts 12 comprises the 16 outward extending flanges 26 from the chamber.Flange 26 comprises flange top 28 and flange bottom surface 30 (referring to Fig. 6).
In the illustrated embodiment that this paper presented, flange 26 stretches out around the periphery in chamber 26 and from it.Flange 26 comprises seal area 40, and seal member 14 can be attached to seal area 40 with annular seal space 16.Flange 26 can be regarded as the part of substrate parts 12, and it 16 stretches out to be provided for the adhering zone of seal member 14 from the chamber.Near the near-end in chamber 16, the proximal end region 18 of the proximal part of flange 26 and substrate parts 12 combines.Described flange can have from about 1 millimeter to about 10 millimeters width, for instance, about 1 millimeter, about 2 millimeters, about 3 millimeters, about 4 millimeters, about 5 millimeters, about 6 millimeters, about 7 millimeters, about 8 millimeters, about 9 millimeters or about 10 millimeters.Therefore, seal member 14 accompanying to seal area 40 can be regarded as from the chamber that 16 edge extends from about 1 millimeter to about 10 millimeters zone.Except that seal area 40, seal member 14 does not adhere to or is coupled to substrate parts 12.Then, the people can in this or these not the adhering zone place firmly grasp seal member 14 and it removed from substrate parts 12.
The indivedual unsealed contact lens packages 10 of graphic extension among Fig. 5.Fig. 6 is the sectional view along the line 6-6 of Fig. 5, and Fig. 7 is the sectional view along the line 7-7 of Fig. 5.
The chamber 16 of the substrate parts 12 of contact lens package 10 is defined by bottom wall surface 34 and chamber sidewall surfaces 35.As shown in Figure 6, bottom wall surface 34 is surfaces of chamber diapire 32.Diapire 32 can be regarded as and comprises first bottom wall surface 34 (for example, defining the basal surface in chamber 16) and the second relative bottom wall surface 36.Diapire 32 has the width that is defined as the distance between the relative bottom wall surface 36 with second of first bottom wall surface 34.Bottom wall surface 34 by bottom wall surface perimeter 37 around.Substrate parts 12 also comprises chamber sidewall 38.Chamber sidewall 38 includes the chamber sidewall surfaces 35 that helps define chamber 16.Substrate parts 12 can be regarded as the chamber 16 that comprises by defining with the lower part: proximal wall part 38a, distal wall part 38b, the first lateral sidewalls part 38c and the second relative lateral sidewalls part 38d (referring to Fig. 6 and 7).Chamber 16 by chamber periphery 39 around.Chamber periphery 39 can be regarded as the upper end that is positioned at chamber sidewall surfaces 35 and the face that the connects place of flange 26.
Chamber 16 comprises cavity segment 42 far away and nearly cavity segment 44, as shown in Fig. 5 and Fig. 6.Cavity segment 42 far away comprises sphere member, and nearly cavity segment 44 comprises non-sphere member.For instance, the bottom wall surface 34 of cavity segment 42 far away can be the part of spherical surface, and the bottom wall surface of nearly cavity segment 44 can be an aspheric surface.As shown in Figure 8, the proximal part 18 of substrate parts 12 comprises first surface 46 and relative second surface 48.First surface 46 and flange top 28 adjacency.Show a plurality of projections 50 among the figure, it extends from first surface 46.Show recess among the figure or cave in 52, it extends (referring to Fig. 5 and 8) from first surface 46 towards second surface 48.Nearly part 18 also comprises the nearly steady component 54 that combines with basal surface 36, and nearly steady component 54 is stabilized in substrate parts 12 on the flat surfaces (for example horizontal surface).Graphic extension ribs 56 among Fig. 8, it extends downwards and around the several portions and the far-end of the cross side of described substrate parts from flange top 28.
The substrate parts of the present invention's packing can be formed by various materials.In some embodiment (comprising illustrated embodiment), described substrate parts is a plastic components.Described substrate parts can be made by any routine techniques.In illustrated embodiment, described substrate parts is through injection-molded element.In other embodiments, described substrate parts can be thermoforming.Therefore, substrate parts of the present invention can be regarded as and comprises thermoplastic, is made up of thermoplastic basically, or is made up of thermoplastic fully.In one embodiment, described substrate parts is made by polyolefin material (for example polypropylene).When the substrate parts of the present invention packing is used for the lens inspection method, described substrate parts material light-transmissive so that the image that is arranged in the contact lenses in described substrate parts chamber and can obtains described eyeglass of can throwing light on for inspection.
Show the diagram of ophthalmic lens check system 100 among Fig. 9.Lens inspection system 100 comprises light source 102, eyeglass 104 and camera 106.The substrate parts 12 of the present invention's packing is between eyeglass 104 and camera 106.Substrate parts 12 comprises liquid 60 in the described chamber and the ophthalmic lens 62 in the described liquid.As described herein, ophthalmic lens 62 can be contact lenses, for example hydrogel contact lens.
As shown in Figure 10, light source 102 provides through guiding and towards the diffused light 110 of eyeglass 104.In illustrated embodiment, light source 102 is light emitting diode (LED).Diffused light 110 is partly collimated by eyeglass 104.Therefore, eyeglass 104 can be regarded as the optical alignment eyeglass, and it converts diffused light 110 to the light 112 that collimates through part effectively.To be directed to the substrate parts 12 of contact lens package 10 through the light 112 of part collimation.The combination cooperation of chamber diapire 34, ophthalmic lens 62 and liquid 60 is collimate described light fully towards the 106 described light time of guiding of camera.Therefore, camera 106 receives parallel rayss 114 and can obtain and produce the even bright field image of described ophthalmic lens.Whether the image that can check described ophthalmic lens has flaw.If do not detect flaw, then described seal member can be sealed to described substrate parts.Then, can carry out disinfection and it is provided and delivered away from spectacles manufacturers through the sealing contact lens package described.
In view of the present invention, the embodiment of contact lens blister packages of the present invention comprises thermoplastic base member.Described thermoplastic base member comprises light collimation cavity.Described light collimation cavity can be regarded as be present in described chamber in liquid and the contact lenses that are arranged in described liquid cooperate so that through the optical alignment of part collimation chamber with even bright field image that described contact lenses are provided during scrutiny program.Described light collimation cavity is through determining that size (for example through determining size and shape) is to be contained in moisture contact lenses in the fluid composition that is present in the described chamber.Described substrate parts also comprises from the outward extending flange of described light collimation cavity.Described flange comprises seal area, and seal member can be attached to described seal area so that described contact lenses and fluid composition are sealed in the described chamber.
As described herein, the light collimation cavity of these embodiment can comprise the curved bottom surface with bottom surface perimeter.Described chamber also can comprise the upwardly extending chamber sidewall surfaces that extends to upper perimeter cavity edge from described bottom surface perimeter.Described upper perimeter cavity edge can be regarded as and defines light collimation cavity perimeter.Described light collimation cavity perimeter is greater than described bottom surface perimeter.In other embodiments, described light collimation cavity perimeter equals described bottom surface perimeter.
In certain embodiments, described crooked light collimation cavity basal surface has and is at least and will be positioned over the big radius-of-curvature of twice of the base curve of the moisture contact lenses in the described chamber.For instance, the base curve of the comparable described moisture contact lenses of described radius-of-curvature greatly at least 200%, greatly at least 300%, or greatly at least 400%.For instance, if moisture contact lenses have about 8 millimeters base curve, the radius-of-curvature of then described chamber basal surface can be at least 16 millimeters, at least 24 millimeters, or at least 32 millimeters.In certain embodiments, the radius-of-curvature of described chamber basal surface is from about 15 millimeters to about 26 millimeters.Described radius-of-curvature can be along the length in described chamber and identical along the width in described chamber, and perhaps they can be different.For instance, at least one embodiment, described chamber basal surface along the length of described basal surface have from about 25 millimeters to about 26 millimeters radius-of-curvature, and have the same curvature radius along the width of described basal surface.
Some embodiment of contact lens blister packages of the present invention comprises the chamber sidewall, and described chamber sidewall is to extend from described plain-straight-face flange zone towards the central area of described light collimation cavity to about 90 ° angle from about 80 °.In certain embodiments, described angle is less than 90 °.Come directed described sidewall or its part to can be useful in order to the adequate space that holds moisture contact lenses with these angles for providing.Being appreciated that does not need described whole sidewall is oriented between about 80 ° and about 90 °.For instance, as mentioned in institute discuss, along the nearly part in described chamber, described sidewall can have more shallow slope, described slope promotion remove from described chamber can be aspect the described contact lenses useful.The substrate parts of blister package of the present invention also can comprise proximal end region with thumb grip region, relatively remote area, from described proximal end region extend to described relative remote area territory, first lateral areas, and extend to described relative remote area and the relative second lateral areas territory roughly relative with territory, first lateral areas from described proximal end region.Described light collimation cavity is between described proximal end region and described remote area, and between first and second territory, lateral areas.
As shown in Fig. 6 and Fig. 7, described substrate parts can have the length L that extends to described relative remote area from described proximal end region.Described substrate parts also can have the width W that extends to territory, described relative second lateral areas from territory, first lateral areas.Described light collimation cavity has the cavity length that is parallel to described substrate parts length, and has the chamber width that is parallel to described substrate parts width.In some embodiment (comprising illustrated embodiment), described cavity length is greater than described chamber width.For instance, described chamber width can be from about 60% to about 90% of a described cavity length.In certain embodiments, maximum cavity width is about 80% of a maximum cavity length.As described herein, the slope of the sidewall surfaces in described chamber can change.For instance, the illustrated embodiment of the present invention's packing comprises the chamber with chamber sidewall, and described chamber sidewall has the proximal wall part, and described proximal wall partly has with the more distal part of described chamber sidewall compares more shallow slope.Comprise described basal surface and sidewall surfaces shape the chamber be configured in make described eyeglass for example during checking remain in the desired location in the described chamber aspect can be useful, and can be aspect promoting described contact lenses are removed to from described chamber on people's the finger useful.In view of the invention of this paper, some embodiment of light collimation cavity of the present invention can be regarded as has the chamber periphery that roughly is egg type, and the proximal end region of more approaching described substrate parts is compared in the position of narrow part of wherein said periphery with the relative far-end of described substrate parts.Other embodiment can comprise the periphery of other shape, comprises ellipse, avette, droplet shape even circle (if desired).In certain embodiments, when described packing is positioned on the horizontal surface and described chamber opening up the time, it is roughly placed in the middle that described contact lenses keep in described chamber.
The state that depends on blister package of the present invention, some embodiment comprise the liquid that is arranged in described light collimation cavity and are immersed in the contact lenses of described liquid fully.For instance, if described blister package be positioned at production line lens inspection platform place, be positioned at production line sealing platform place, be positioned at the sterilization platform place of a production line, or being positioned at home-delivery center or other memory location (comprising doctor's office or lens wearer residence) when locating, described blister package comprises liquid that is arranged in described chamber and the contact lenses that are arranged in described liquid.Described liquid can be regarded as contact lens packaging solutions.The example of contact lens packaging solutions comprises brine solution, for example through buffered saline solution.Some instantiation comprise borate through buffer solution, phosphate through buffer solution, supercarbonate through buffer solution and similar solution.In certain embodiments, the liquid in the described chamber comprises surfactant, for example non-ionics.The example that can be contained in the surfactant in the packing liquid of the present invention comprise can be used as the poloxamer that Pluronics openly buys and can be used as guarantor that Tetronics openly buys beautiful look bright.Other surfactant comprises polysorbate, and for example TWEEN comprises TWEEN-80.The amount of surfactant can be between counting in the scope of about 2.0 percent by weight from about 0.005 weight percent.Described liquid can comprise other preparation additionally or alternati, for example polyvinyl alcohol (PVA), polyvinylpyrrolidone, cellulose derivative (for example carboxymethyl cellulose, hydroxypropyl methylcellulose, hydroxyethyl cellulose, methylcellulose and methyl ether cellulose) and polyglycol.
Another embodiment of contact lens blister packages comprises thermoplastic base member, and described thermoplastic base member comprises the light collimation cavity that is defined by bottom wall surface.Described bottom wall surface has periphery, and described chamber further defined by sidewall surfaces, described sidewall surfaces from described bottom wall surface perimeter upwards towards outward extending flange extends from described chamber.In this embodiment, described chamber has about 25 millimeters maximum length and about 20 millimeters breadth extreme, and described bottom wall surface have from about 15 millimeters to about 26 millimeters radius-of-curvature.
As noted before, the bottom wall surface of this embodiment can be the surface of chamber diapire.In certain embodiments, described chamber diapire has the thickness less than 1 millimeter.In further embodiment, the thickness of described diapire is about 0.8 millimeter.In certain embodiments, the thickness of described diapire is crossed over described whole diapire and constant.For instance, the thickness of described diapire can change to 0.85 millimeter from 0.75 millimeter.
The chamber of the present invention's packing is through determining that size is to hold moisture contact lenses.Therefore, the chamber can have depth capacity so that moisture contact lenses can be immersed in the fluid composition that is present in the described chamber fully.In certain embodiments, described chamber has the depth capacity less than 9 millimeters.For instance, described chamber can have about 6 millimeters, about 7 millimeters, about 8 millimeters or about 9 millimeters depth capacity.In at least one embodiment, described chamber has about 7.0 millimeters depth capacity.
Some embodiment of described blister package comprises the chamber with sidewall surfaces, the second lateral sidewalls part relative with the first lateral sidewalls part that described sidewall surfaces comprises proximal wall part, distal wall part, first lateral sidewalls partly reaches.With extend from described bottom wall surface and perpendicular to one or more into about the directed described distal wall part of the angles of 5 degree, described first lateral sidewalls part and described second lateral sidewalls part of the straight line of the top surface of described flange.
The substrate parts of the present invention packing also can comprise can be by the proximal end region of people's finger grip, thumb grip region for example described herein.In certain embodiments, described proximal end region comprises first surface that the top surface with described flange continues and a plurality of protuberance projections that extend from first surface.In some embodiment (for example described embodiment), described proximal end region can comprise from the outstanding groove of first surface.In extra embodiment, described proximal end region can comprise mark, for example numeral, letter, figure and combination thereof.For instance, thumb grip region can comprise the trade name of the contact lenses that are arranged in described chamber.Described mark can be provided on the described thumb grip region by ink form, perhaps can be the ridge structure that is similar to described protuberance projection and produces during the manufacturing of described substrate parts.
In certain embodiments, the flange of described substrate parts has about 3 millimeters breadth extreme.Described substrate parts also can have about 27 millimeters breadth extreme, about 46 millimeters maximum length.
Another embodiment that is presented herein is a kind of thermoplastic base member that is used for contact lens blister packages.As described herein, described substrate parts has length and width.Described substrate parts comprises the chamber, the sidewall surfaces that described chamber has bottom wall surface and extends from described bottom wall surface along periphery.Described substrate parts also comprises from the outward extending flange in described chamber.The bottom wall surface in described chamber along the length of described substrate parts and along the width of described substrate parts have from about 15 millimeters to about 26 millimeters radius-of-curvature.In other words, the radius-of-curvature of described bottom wall surface equates along both direction (for example, along the length of described substrate parts and along the width of described substrate parts).In certain embodiments, described bottom wall surface is the surface with diapire of about 0.8 millimeter thickness.In extra embodiment, described radius-of-curvature is from about 25 millimeters to about 26 millimeters.In further embodiment, described chamber has about 7 millimeters depth capacity.But described substrate parts can comprise nearly finger grip area, and described chamber has near-end, and described near-end has the width less than the distal end width in described chamber.For instance, described chamber can have configuration as shown in Figure 5.In addition, as described herein, described substrate parts can further comprise hang on the described flange and with the isolated ribs in described chamber.
In addition, as described herein, the contact lenses that can be present in the liquid of described chamber comprise silicone hydrogel contact lens and non-silicone hydrogel contact lens.In certain embodiments, the present invention comprises day throwing type contact lenses, for example set contact lenses of wearing about 10-16 hour and then abandoning.
The present invention's packing also can comprise the seal member that is attached to the seal area of described flange in removable mode.Accompanying seal member form contain described liquid and contact lenses through can.In certain embodiments, described seal member is attached to described substrate parts after lens inspection procedure.Therefore, these embodiment can be regarded as back inspection formula contact lens blister packages.
As described herein, the substrate parts of the present invention's packing can be made by various thermoplastics.In certain embodiments, described substrate parts is through injection-molded polyolefine material.For instance, some substrate parts in the described substrate parts (comprising illustrated substrate parts) are formed by polypropylene.
As shown in graphic, blister package of the present invention can be coupled to form array of contact lens blister packages.As described herein, array of the present invention can be formed by being arranged to two, three, four, five, six of band or six above blister packages.
The instantiation of one contact lens blister packages comprises that through injection-molded polypropylene-base bottom parts, described substrate parts comprises chamber and outward extending flange.When look in the top, described chamber has oval configuration, as shown in Figure 5.Described chamber has about 25 millimeters and arrives about 26 millimeters maximum length, about 20 millimeters breadth extreme and about 7 millimeters depth capacity.The basal surface in described chamber has the single radius-of-curvature between about 25 millimeters and about 26 millimeters along X and Y the both direction length and the width of described chamber (for example, along).The wall thickness of described substrate parts is about 0.80 millimeter.The total length of described substrate parts is about 46 millimeters, and overall width is about 26 to about 27 millimeters.Seal area width around the described chamber is about 3.0 millimeters.The proximal end region of described substrate parts comprises thumb grip with a plurality of protuberance projections and the groove that is formed by injection-molded program.The nearly part in described chamber has with respect to the top surface of the described flange sloped sidewall with about 30 ° angle orientation.
Can use to the conventional method known to the those skilled in the art and make packing of the present invention and array of packages.For instance, the substrate parts of described packing and array of packages can form by thermoplastic resin material is injection-molded in injecting molding machine.Can be in the chamber of described substrate parts obtaining liq, contact lens packaging solutions for example, and contact lenses can being embedded in the described liquid.Perhaps, contact lenses can be placed in the described chamber, and then can be in described chamber obtaining liq.Then, described seal member can be applied to the seal area of described substrate parts so that described liquid and contact lenses are sealed in the described chamber.Then, can be to containing the carrying out disinfection and prepare of described moisture contact lenses for dispensing through packing.
Usually, before described seal member is applied to described substrate parts, can check the eyeglass that is arranged in described chamber.Described inspection can be manually or is automatic.Automatic check method can help the production of a large amount of contact lenses.Therefore, a kind of method of checking moisture contact lenses is included in the liquid in the chamber that is present in packing described herein contact lenses is provided.Guiding is passed described chamber, described liquid and described contact lenses to produce the light of collimation fully through the light of part collimation.Use one to receive the bright field image that the described camera of the light of collimation fully obtains described contact lenses.Then, described image can be sent to computing machine for processing, for example by using described image to move one or more lens inspection algorithms.Can be in turn or put into practice described method concurrently.For instance, in certain embodiments, for example when the blister package array is used for contact lenses production, simultaneously a plurality of packings are carried out described method.By produce the even illumination to described contact lenses based on the unique bottom surface configuration in described chamber, described lens edge and eyeglass flaw can be by the light blasts of described collimation.
The various additional features of described blister package and substrate parts can be provided.For example, the embodiment of packing of the present invention and substrate parts can comprise the chamber with non-planar proximal wall part.Unitary package or substrate parts can be regarded as and comprise only chamber, and for instance, unitary package can comprise the substrate parts of being made up of chamber, flange and thumb grip region.Described packing can not contain the mark that indication is housed in the diameter of contact lenses wherein.Described packing or substrate parts can not contain and be used to be grasped in the relative impression with the side direction between the forefinger of thumb.The chamber of described packing or substrate parts can not contain from the chamber basal surface and extends to raised ribs the described chamber.In addition, as described herein, the radius-of-curvature of the basal surface in described chamber can be far longer than 12 millimeters.Described chamber can be regarded as and not contain the contact lenses clamping lip that extends internally that extends towards the center in described chamber from described lug area.In addition, described chamber can be regarded as the single ventricle that is used to store described contact lenses.Described chamber diapire can be regarded as and not turn-over.In certain embodiments, packing of the present invention and substrate parts comprise non-semicircle chamber, non-rectangle flange or both.
The embodiment of the present invention's packing does not contain the groove in order to the peripheral part of admitting described flexible lid thin slice.Some embodiment of packing of the present invention and substrate parts can be regarded as and not contain a plurality of interlockable or legs of interlock mutually.The chamber of described packing and substrate parts can be regarded as and not contain from the upwardly extending convex mold part of the basal surface in described chamber.As discussed herein, the embodiment of packing of the present invention and substrate parts can have the chamber, and described chamber has the diapire greater than 0.75 millimeter thickness.In addition, some embodiment can have the chamber of containing more than 0.75 milliliter packaging solution.
Although this paper invention relates to some specific embodiment, should be understood that these embodiment are that the mode unrestricted with example presents.Based on context, this instructions and those skilled in the art's knowledge any feature described herein or characteristics combination all are contained in the scope of the present invention, and precondition is:, will understand that the feature that be contained in any this type of combination is not conflicting.In addition, any feature or characteristics combination all can clearly be excluded in outside any embodiment disclosed herein.Though discussed exemplary embodiment, the intention of above-mentioned detailed description should be considered as containing all modifications, replacement scheme and the equivalent of the embodiment described in this specification and claims book.

Claims (45)

1. contact lens blister packages, it comprises:
Thermoplastic base member, it comprises: light collimation cavity, it has liquid and the contact lenses that are present in the described light collimation cavity; And flange, it stretches out from described light collimation cavity, described flange comprises seal area, seal member can be attached to described seal area with described contact lenses and described hydraulic seal in described chamber;
Wherein said light collimation cavity comprises: basal surface, and it has bottom surface perimeter; And upwardly extending chamber sidewall surfaces, it extends to the upper perimeter cavity edge that defines light collimation cavity perimeter from described bottom surface perimeter, and
Wherein said light collimation cavity perimeter is greater than described bottom surface perimeter; And wherein said light collimation cavity basal surface has the radius-of-curvature than the base curve big at least 200% of described contact lenses.
2. packing as claimed in claim 1, wherein said contact lenses are silicone hydrogel contact lens.
3. packing as claimed in claim 1, it further comprises the seal member that is attached to the described seal area of described flange in removable mode, thereby form contain described liquid and contact lenses through can.
4. packing as claimed in claim 1, wherein said chamber sidewall is to extend from the plain-straight-face flange zone towards the central area of described light collimation cavity from 80 ° to the angle less than 90 °.
5. packing as claimed in claim 4, wherein said substrate parts further comprises: proximal end region, it has thumb grip region; Relative remote area, it is roughly relative with described proximal end region; Territory, first lateral areas, it extends to described relative remote area from described proximal end region; And territory, relative second lateral areas, it extends to described relative remote area and roughly relative with territory, described first lateral areas from described proximal end region, and wherein said light collimation cavity is between described proximal end region and described relative remote area and between described territory, first lateral areas and the territory, described relative second lateral areas.
6. packing as claimed in claim 5, wherein said substrate parts has from described proximal end region and extends to the length of described relative remote area and extend to the width in territory, described relative second lateral areas from territory, described first lateral areas, and described light collimation cavity has the cavity length that is parallel to described substrate parts length and has the chamber width that is parallel to described substrate parts width, and wherein said cavity length is greater than described chamber width.
7. packing as claimed in claim 1, wherein said contact lenses are immersed in the described liquid fully.
8. packing as claimed in claim 1, wherein said liquid are through buffered saline solution.
9. packing as claimed in claim 1, wherein said contact lenses are day throwing type contact lenses.
10. packing as claimed in claim 1, wherein said liquid comprises surfactant.
11. packing as claimed in claim 1, wherein said substrate parts are through injection-molded polyolefine material.
12. packing as claimed in claim 1, it is coupled at least one other same package to form the eyeglass array of packages.
13. packing as claimed in claim 6, wherein said chamber sidewall has the proximal wall part, the described proximal end region of more approaching described substrate parts is compared in its position with the described relative remote area of described substrate parts, described proximal wall partly has with the more distal part of described chamber sidewall compares more shallow slope.
14. packing as claimed in claim 13, wherein said light collimation cavity perimeter roughly is egg type, and the described proximal end region of more approaching described substrate parts is compared in the position of narrow part of described light collimation cavity perimeter with the described relative far-end of described substrate parts.
15. packing as claimed in claim 1 wherein is positioned on the horizontal surface and described chamber opening up the time when described packing, it is roughly placed in the middle that described contact lenses keep in described chamber.
16. a contact lens blister packages, it comprises:
Thermoplastic base member, it comprises liquid and the contact lenses that are arranged in light collimation cavity, described light collimation cavity is defined by bottom wall surface and sidewall surfaces, described bottom wall surface has periphery, described sidewall surfaces makes progress towards outward extending flange extends from described chamber from described bottom wall surface perimeter, described flange comprises seal area, and removable seal member can be coupled to described seal area
Wherein said chamber has 25 millimeters maximum length and 20 millimeters breadth extreme, and described bottom wall surface has the radius-of-curvature than the base curve big at least 200% of described contact lenses.
17. packing as claimed in claim 16, wherein said bottom wall surface are the surfaces of chamber diapire, and described chamber diapire has the thickness less than 1 millimeter.
18. packing as claimed in claim 16, wherein said substrate parts further comprises can be by the proximal end region of people's finger grip, and described proximal end region comprises first surface that the top surface with described flange continues and a plurality of protuberance projections that extend from described first surface.
19. packing as claimed in claim 18, wherein said proximal end region further comprise the mark that is selected from the group that is made up of numeral, letter, figure and combination thereof.
20. packing as claimed in claim 16, wherein said contact lenses are immersed in the described liquid fully.
21. packing as claimed in claim 17, wherein said chamber has 7 millimeters depth capacity.
22. packing as claimed in claim 16, the second lateral sidewalls part relative that wherein said sidewall surfaces comprises proximal wall part, distal wall part, first lateral sidewalls partly reaches with the first lateral sidewalls part, at least one in described distal wall part, described first lateral sidewalls part and described second lateral sidewalls part with extend from described bottom wall surface and become the 5 angle orientations of spending perpendicular to the straight line of the top surface of described flange.
23. packing as claimed in claim 17, wherein said chamber bottom wall thickness is 0.8 millimeter.
24. packing as claimed in claim 18, wherein said proximal end region further comprise from the outstanding groove of described first surface.
25. packing as claimed in claim 16, wherein said flange has 3 millimeters breadth extreme.
26. packing as claimed in claim 16, wherein said substrate parts have 27 millimeters breadth extreme and 46 millimeters maximum length.
27. packing as claimed in claim 20, wherein said liquid are through buffered saline solution.
28. packing as claimed in claim 27, wherein liquid comprises surfactant.
29. packing as claimed in claim 20, wherein said contact lenses are silicone hydrogel contact lens.
30. packing as claimed in claim 16, wherein said contact lenses are silicone hydrogel contact lens.
31. packing as claimed in claim 16, wherein said contact lenses are day throwing type contact lenses.
32. packing as claimed in claim 16, wherein said contact lenses comprise hydroxy acrylic acid methyl esters polymkeric substance and phosphoryl choline derivative.
33. packing as claimed in claim 16, it is coupled at least one other same package to form the eyeglass array of packages.
34. packing as claimed in claim 33, it is present in the array that three glasses packings are formed.
35. packing as claimed in claim 33, it is present in the array that five glasses packings are formed.
36. a method of checking moisture contact lenses, it comprises:
Contact lenses are provided in to be present in the liquid in the light collimation cavity of contact lens blister packages, wherein said light collimation cavity has bottom wall surface, and described bottom wall surface has from 15 millimeters to 26 millimeters radius-of-curvature along the length in described chamber and along the width in described chamber;
Guiding is passed described light collimation cavity and is provided in liquid and contact lenses in the described light collimation cavity through the light of part collimation, to produce the light of collimation fully; And
Use and receive the bright field image that the described camera of the light of collimation fully obtains described contact lenses.
37. method as claimed in claim 36 is wherein carried out described method to a plurality of contact lens packages simultaneously.
38. a contact lens blister packages, it comprises the thermoplastic base member with length and width, and described substrate parts comprises:
Only a light collimation cavity is with the liquid hold-up composition, and described only light collimation cavity has bottom wall surface and sidewall surfaces, and described sidewall surfaces is extended along periphery from described bottom wall surface;
Liquid in the described light collimation cavity and contact lenses; And
From described only outward extending flange of light collimation cavity;
Wherein said bottom wall surface has from 15 millimeters to 26 millimeters radius-of-curvature along the described length of described substrate parts and along the described width of described substrate parts, and wherein said radius-of-curvature is bigger by 200% than the base curve of described contact lenses.
39. contact lens blister packages as claimed in claim 38, wherein said bottom wall surface are the surfaces with diapire of 0.8 millimeter thickness.
40. contact lens blister packages as claimed in claim 39, wherein said radius-of-curvature is from 25 millimeters to 26 millimeters.
41. contact lens blister packages as claimed in claim 39, wherein said light collimation cavity has 7 millimeters depth capacity.
42. contact lens blister packages as claimed in claim 39, but it further comprises nearly finger grip area, and wherein said light collimation cavity comprises near-end and relative far-end, but the approaching described nearly finger grip area of described near-end, and described near-end has the width less than described distal end width.
43. contact lens blister packages as claimed in claim 38, wherein said contact lenses are silicone hydrogel contact lens.
44. contact lens blister packages as claimed in claim 38, its further comprise hang on the described flange and with the isolated ribs of described light collimation cavity.
45. contact lens blister packages as claimed in claim 38, it further comprises the removable seal member that is coupled to described flange.
CN2007800451911A 2006-12-07 2007-12-06 Contact lens blister packages and methods for automated inspection of hydrated contact lenses Active CN101548152B (en)

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PCT/US2007/086652 WO2008070782A2 (en) 2006-12-07 2007-12-06 Contact lens blister packages and methods for automated inspection of hydrated contact lenses

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