CN101537149A - Pharmaceutical composition for curing eczema - Google Patents
Pharmaceutical composition for curing eczema Download PDFInfo
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- CN101537149A CN101537149A CN200810102435A CN200810102435A CN101537149A CN 101537149 A CN101537149 A CN 101537149A CN 200810102435 A CN200810102435 A CN 200810102435A CN 200810102435 A CN200810102435 A CN 200810102435A CN 101537149 A CN101537149 A CN 101537149A
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Abstract
The invention relates to a pharmaceutical composition for curing eczema. The pharmaceutical composition is prepared by the following raw materials according to proportioning by weight: 100-200 parts of kuhseng, 100-200 parts of tuber fleeceflower, 30-60 parts of hairy vein agrimony, 50-100 parts of belamcanda rhizome, 50-100 parts of goldenlarch bark, 30-60 parts of stenona root, 50-100 parts of cnidium fruit, 50-100 parts of Chinese gall, 30-60 parts of sophora flower-bud, 50-100 parts of Chinese dittany bark, 50-100 parts of mulberry leaf, 100-200 parts of dried rehmannia root and 50-100 parts of dark plum and is prepared into clinically accepted tablets, capsules or granules by processing through extracting, refining and other processes. The invention has the effects of clearing heat and drying damp and expelling wind and relieving itching and is used for wind heat syndromes such as eczema, acne, tinea versicolor, and the like.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of drug regimen for the treatment of eczema and preparation method thereof.
Technical background
Eczema is a kind of common skin inflammatory dermatosis, has with erythra infringement place and oozes out moist tendency and the event name.Difficult more, the easily recurrence of this disease course of disease delay.
Eczema clinical symptoms change multiterminal, different according to the performance of the skin lesion in the pathogenic process, be divided into acute, subacute and chronic three types.The infringement pleomorphism of acute eczema, the initial stage is erythema, conscious scorching hot, pruritus.Occurring on erythema of continuing is dispersed in or intensive pimple or phlysis, after scratching or rubbing, scratches brokenly and forms rotten to the corn, sepage face.With the passing of time or treatment back acute inflammation alleviates, skin lesion drying, incrustation, squama, enter subacute stage.Chronic eczema is more not developed by acute, subacute outbreak repeatedly, or presents chronic inflammatory disease when beginning, and is not characteristics more to be confined to a certain same area prolonged often, shows as skin progressive additive, dermatoglyph intensification, infiltration, pigmentation etc.Main subjective symptoms is violent pruritus.
Though eczema has above-mentioned common clinical manifestation, the eczema of different parts, its skin lesion form also has certain difference.As the eczema of external auditory canal fungal infection that easily occurs together, breast eczema is common in women breast-feeding their children, often chaps and accompanies pain.Anus, eczema scrotum Chang Yin scratch, hot water is soaped and arrived acute swelling or erosion.Legs eczema often causes and festers, and is difficult for healing etc.Except that above-mentioned, also have part to show ordinary special type eczema clinically, as be secondary to the infectious eczematoid dermatitis of bacillary suppurative dermatosis such as otitis media, ulcer, fistula and decubital ulcer, and the autosensitization eczema that cause irritated to the material that produced from body inner skin tissue, the good infantile eczema of sending out infantile period behind full moon, normal symmetry occurs in the back of the hand, extremity are stretched side and buttocks, and the skin lesion shape is like the nummular eczema of coin.
The traditional Chinese medical science is different because of the position to the name of primary disease, be equivalent to universal eczema as " acute eczema ", " seborrheic dermatitis " is equivalent to facial eczema, " eczema of ear " are equivalent to ear eczema, " cracked nipple " is equivalent to eczema of nipple, " umbilical sore " is equivalent to umbilical part eczema, " eczema of scrotum ", " scrotal eczema " more than eczema scrotum, " atopic eczema " is equivalent to the fossa cubitalis and poples eczema, " fungal infection of hand and foot " is equivalent to metacarpus eczema, " ecthyma " is equivalent to legs eczema, and " anus circle tinea " is equivalent to anal eczema.Motherland's medical science thinks that eczema is because natural disposition is not anti-, accumulates in the wind heat, and the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, the rheumatism pathogenic heat is fought mutually, and the contamination skin forms.Wherein " wetting " is principal element.Because damp is sticky, deep, variable, so sick many delays, form is indefinite.And chronic eczema is because nutrient QI and blood being insufficient, damp and hot staying, so that the blood deficiency impairment of YIN, and wind is given birth in dryness-transformation, and the damp and hot pent-up of wind-dryness is due to the failure of skin and muscle to be nourished.
The present invention is to be a kind of Chinese medicine composition with heat clearing and damp drying, dispelling wind itching-relieving action that develop in conjunction with present herbal pharmaceutical technology on the basis with the Traditional Chinese medical theory.
Summary of the invention:
One of purpose of the present invention provides a kind of drug regimen for the treatment of eczema.
Another object of the present invention provides the preparation method of this drug regimen.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription:
Radix Sophorae Flavescentis 100-200 part Radix Polygoni Multiflori 100-200 part Herba Agrimoniae 30-60 part
Rhizoma Belamcandae 50-100 part Cortex Pseudolaricis 50-100 part Radix Stemonae 30-60 part
Fructus Cnidii 50-100 part Galla Chinensis 50-100 part Flos Sophorae Immaturus 30-60 part
Cortex Dictamni 50-100 part Folium Mori 50-100 part Radix Rehmanniae 100-200 part
Fructus Mume 50-100 part Alumen 30-60 part sodium benzoate 2-4 part
The active component that preferred following raw materials according is made, curative effect is better:
50 parts of 150 parts of Herba Agrimoniaes of 150 parts of Radix Polygoni Multiflori of Radix Sophorae Flavescentis
50 parts of 80 parts of Radixs Stemonae of 80 parts of Cortex Pseudolariciss of Rhizoma Belamcandae
50 parts of 80 portions of Flos Sophorae Immaturus of 80 parts of Galla Chinensiss of Fructus Cnidii
150 parts of 80 parts of Radix Rehmanniae of 80 parts of Folium Mori of Cortex Dictamni
3 parts of 50 parts of sodium benzoate of 80 parts of Alumens of Fructus Mume
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Radix Sophorae Flavescentis, Cortex Pseudolaricis, the Radix Stemonae add the airtight dipping of 60% ethanol 2-3 time, each 12-24 hour, filter merging filtrate;
(2) Radix Polygoni Multiflori, Herba Agrimoniae, Rhizoma Belamcandae, Fructus Cnidii, Galla Chinensis, the Flos Sophorae Immaturus, Cortex Dictamni, Folium Mori, Radix Rehmanniae, Fructus Mume decoct with water 2-3 time, and each 1-2 hour, filter, merging filtrate concentrates, and adds Alumen while hot, stirs and makes dissolving;
(3) above-mentioned two solution are merged, add the 10mol/L sodium hydroxide solution and regulate pH value to 5.0, left standstill 24 hours, filter, filtrate adds sodium benzoate, stirs and makes dissolving, adds water to ormal weight, filters, promptly.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has heat clearing and damp drying, dispelling wind is antipruritic.Be used for eczema, acne, tinea versicolor and belong to the malicious card person of wind heat temperature.
By the following examples technical scheme of the present invention is described further.
Embodiment 1
1. write out a prescription:
50 parts of 150 parts of Herba Agrimoniaes of 150 parts of Radix Polygoni Multiflori of Radix Sophorae Flavescentis
50 parts of 80 parts of Radixs Stemonae of 80 parts of Cortex Pseudolariciss of Rhizoma Belamcandae
50 parts of 80 portions of Flos Sophorae Immaturus of 80 parts of Galla Chinensiss of Fructus Cnidii
150 parts of 80 parts of Radix Rehmanniae of 80 parts of Folium Mori of Cortex Dictamni
3 parts of 50 parts of sodium benzoate of 80 parts of Alumens of Fructus Mume
2. preparation technology
(1) Radix Sophorae Flavescentis, Cortex Pseudolaricis, the Radix Stemonae add the airtight dipping secondary of 60% ethanol, 24 hours for the first time, 12 hours for the second time, filter merging filtrate;
(2) Radix Polygoni Multiflori, Herba Agrimoniae, Rhizoma Belamcandae, Fructus Cnidii, Galla Chinensis, the Flos Sophorae Immaturus, Cortex Dictamni, Folium Mori, Radix Rehmanniae, Fructus Mume decoct with water three times, and 2 hours for the first time, each 1 hour later on, filter, merging filtrate concentrates, and adds Alumen while hot, stirs and makes dissolving;
(3) above-mentioned two solution are merged, add the 10mol/L sodium hydroxide solution and regulate pH value to 5.0, left standstill 24 hours, filter, filtrate adds sodium benzoate, stirs and makes dissolving, adds water to ormal weight, filters, promptly.
Claims (5)
1, a kind of drug regimen for the treatment of eczema is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Radix Sophorae Flavescentis 100-200 part Radix Polygoni Multiflori 100-200 part Herba Agrimoniae 30-60 part
Rhizoma Belamcandae 50-100 part Cortex Pseudolaricis 50-100 part Radix Stemonae 30-60 part
Fructus Cnidii 50-100 part Galla Chinensis 50-100 part Flos Sophorae Immaturus 30-60 part
Cortex Dictamni 50-100 part Folium Mori 50-100 part Radix Rehmanniae 100-200 part
Fructus Mume 50-100 part Alumen 30-60 part sodium benzoate 2-4 part
2, a kind of drug regimen for the treatment of eczema according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
50 parts of 150 parts of Herba Agrimoniaes of 150 parts of Radix Polygoni Multiflori of Radix Sophorae Flavescentis
50 parts of 80 parts of Radixs Stemonae of 80 parts of Cortex Pseudolariciss of Rhizoma Belamcandae
50 parts of 80 portions of Flos Sophorae Immaturus of 80 parts of Galla Chinensiss of Fructus Cnidii
150 parts of 80 parts of Radix Rehmanniae of 80 parts of Folium Mori of Cortex Dictamni
3 parts of 50 parts of sodium benzoate of 80 parts of Alumens of Fructus Mume
3, according to the described a kind of drug regimen for the treatment of eczema of claim 1-2, it is characterized in that adopting following method to make:
(1) Radix Sophorae Flavescentis, Cortex Pseudolaricis, the Radix Stemonae add the airtight dipping of 60% ethanol 2-3 time, each 12-24 hour, filter merging filtrate;
(2) Radix Polygoni Multiflori, Herba Agrimoniae, Rhizoma Belamcandae, Fructus Cnidii, Galla Chinensis, the Flos Sophorae Immaturus, Cortex Dictamni, Folium Mori, Radix Rehmanniae, Fructus Mume decoct with water 2-3 time, and each 1-2 hour, filter, merging filtrate concentrates, and adds Alumen while hot, stirs and makes dissolving;
(3) above-mentioned two solution are merged, add the 10mol/L sodium hydroxide solution and regulate pH value to 5.0, left standstill 24 hours, filter, filtrate adds sodium benzoate, stirs and makes dissolving, adds water to ormal weight, filters, promptly.
4, according to any one described a kind of drug regimen for the treatment of eczema among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of drug regimen for the treatment of eczema of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810102435A CN101537149A (en) | 2008-03-21 | 2008-03-21 | Pharmaceutical composition for curing eczema |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810102435A CN101537149A (en) | 2008-03-21 | 2008-03-21 | Pharmaceutical composition for curing eczema |
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| CN101537149A true CN101537149A (en) | 2009-09-23 |
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| CN200810102435A Pending CN101537149A (en) | 2008-03-21 | 2008-03-21 | Pharmaceutical composition for curing eczema |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772543A (en) * | 2012-07-31 | 2012-11-14 | 陈美玉 | Orally-taken traditional Chinese medicine for treating tinea versicolor |
| CN103083601A (en) * | 2013-03-01 | 2013-05-08 | 李玉娟 | Traditional Chinese medical composition for treating pompholyx |
| CN103301259A (en) * | 2013-06-03 | 2013-09-18 | 安徽华佗国药股份有限公司 | Preparation method of medicament for clearing heat, drying damp, dispelling wind and relieving itching |
| CN104258137A (en) * | 2014-09-26 | 2015-01-07 | 洛阳华以生物工程有限公司 | Traditional Chinese medicine formula for treating eczema |
| CN106110121A (en) * | 2016-07-23 | 2016-11-16 | 孙茂志 | A kind of Chinese medicine composition treating tinea versicolor |
-
2008
- 2008-03-21 CN CN200810102435A patent/CN101537149A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772543A (en) * | 2012-07-31 | 2012-11-14 | 陈美玉 | Orally-taken traditional Chinese medicine for treating tinea versicolor |
| CN103083601A (en) * | 2013-03-01 | 2013-05-08 | 李玉娟 | Traditional Chinese medical composition for treating pompholyx |
| CN103083601B (en) * | 2013-03-01 | 2014-04-09 | 李玉娟 | Traditional Chinese medical composition for treating pompholyx |
| CN103301259A (en) * | 2013-06-03 | 2013-09-18 | 安徽华佗国药股份有限公司 | Preparation method of medicament for clearing heat, drying damp, dispelling wind and relieving itching |
| CN104258137A (en) * | 2014-09-26 | 2015-01-07 | 洛阳华以生物工程有限公司 | Traditional Chinese medicine formula for treating eczema |
| CN106110121A (en) * | 2016-07-23 | 2016-11-16 | 孙茂志 | A kind of Chinese medicine composition treating tinea versicolor |
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Open date: 20090923 |