CN101536930A - Miniature multifunctional gas exposure device and manufacturing method thereof - Google Patents
Miniature multifunctional gas exposure device and manufacturing method thereof Download PDFInfo
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- CN101536930A CN101536930A CN200810045037A CN200810045037A CN101536930A CN 101536930 A CN101536930 A CN 101536930A CN 200810045037 A CN200810045037 A CN 200810045037A CN 200810045037 A CN200810045037 A CN 200810045037A CN 101536930 A CN101536930 A CN 101536930A
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Abstract
The invention relates to a biomedicine exposure experimental device and a manufacturing method thereof, further relates to a gas exposure experimental device and a manufacturing method thereof. The device comprises a miniature air supply motor (3), a detachable and movable multifunctional transparent exposure chamber (5), a set of air supply pipeline (2) and control valve(4) connected with the air supply motor and the exposure chamber, and a set of exhaust pipe (6) and waste gas collection bag (7) integrated with the exposure chamber. The miniature air supply motor (3) consists of a miniature fan and a control circuit (11) thereof. A remote circuit can be used to control the switching time and air speed of the fan so as to adjust the exposure time and dosage. The gas exposure chamber (5) which is made of transparent glass, transparent plastic or an IVC rat box can be integrally disassembled and assembled, be opened and closed, and be moved and changed. Food stuff and drinking water can be added into the gas exposure chamber. Gas filters can be arranged at the gas inlet and gas outlet of the gas exposure chamber so as to carry out gas filtering treatment and protective device performance evaluation.
Description
Affiliated technical field
The present invention relates to a kind of biomedical exposure experiment equipment and preparation method thereof, further relate to a kind of gas exposure experimental provision and preparation method thereof.
Technical background
Gas exposure experiment (gas exposure) is the basic skills of gas toxicity assessment; It is the research multiple gases, comprise aerosol, aerosol, gas-liquid mixture, dusty gas, particularly sucting reaction, dynamic metabolism and Pathophysiology effect thereof and machine-processed important method such as biological medicine aerosol, anesthetic gases, contaminated air, vehicle exhaust, industrial waste gas, military toxic agent and propellant combustion tail gas; Also be research, the basic skills of estimating toxic and harmful safeguard procedures, protective gear and innoxious process for treating, its scientific research and application are wide.According to the different of the gas flow and the mode of adding of contaminating, the gas exposure experiment is divided into quiet formula (attitude), dynamic formula (attitude) and hybrid, all finish (1.Drew RT.GeneralPrinciple of Inhalation Toxicology.Springer-Verlag by special use suction contamination equipment or device, Berlin, 1985,1-22; 2. Yin Song, Wang Shujie, Bi Wenfang, etc. industrial chemical toxicity is identified standard and experimental technique. Beijing: and the People's Health Publisher, 1998,10-12).Existing these contamination equipment or device need complicated static state or dynamic air-distributing, plenum system and gas monitor spare; Some suck toxicity contaminated systems also needs (Chinese patent application number: 88101517 such as analog gas preparation and sprayer unit; 02222542; 02240058; 200320117313; 200520026707; 200520035257; 200610033156; 200710027786).The major defect of these devices is manufacturing technology complexity, involve great expense, move difficulty, be not easy to carry out on-the-spot exposure experiment and long-term chronic exposure experiment especially, the complexity that also is difficult to simulated field gas change with the operating personnel repeatedly, the practical situation that repeatedly contacts; Static contamination device to distribution, supply gas and concentration detects and requires more complicated, be difficult to avoid animal self to get rid of the interference of gas, range of application is limited, experimental precision and usefulness are low, are unsuitable for containing the exposure experiment and the toxicity assessment of mists such as room airs such as oxycarbide, nitrogen oxide, atmosphere, combustion tail gas.
Summary of the invention
The purpose of this invention is to provide a kind of easy, science, practical gas exposure experiment new equipment and preparation method thereof.This device belongs to a kind of small-size multifunction mobile phase gas exposure device, can be separately or be installed on the moveable platform in batch, connect circuit for remotely controlling, carry out repeatedly, repeatedly, for a long time, the performance evaluation of remote gas exposure experiment, toxicologic study and harmful gas protective gear.
The advantage of this gas exposure device and preparation method thereof is:
(1) described gas exposure device comprises a miniature air supply motor, a dismantled and assembled and mobile multifunctional transparent toxicant exposure chamber, one cover connects the aspirating pipeline and the control valve of above-mentioned air supply motor and toxicant exposure chamber, exhaustor and gas sampling bag that a cover combines with the toxicant exposure chamber; It is simple in structure, and equipment is cheap, makes easily.
(2) described gas exposure device has a miniature air supply motor, described miniature air supply motor is made up of mini fan and control circuit thereof, continue or the interrupted contamination gas of carrying to the toxicant exposure chamber by aspirating pipeline, pass through remote circuit, control fan switch time and air velocity are regulated contamination time and dosage.
(3) described gas exposure device has a toxicant exposure chamber, and there is an air inlet described toxicant exposure chamber, links by aspirating pipeline and control valve and described miniature air supply motor; There is a gas outlet described toxicant exposure chamber, links by exhaustor and gas sampling bag; Described toxicant exposure chamber can pass through air inlet, the gas outlet forms gas flow, keep gas componant and concentration in the toxicant exposure chamber consistent with requirement of experiment gas or gas on-site, avoid animal to get rid of gas or the interference of other gas, to overcome the shortcoming of static QI invigorating contamination device.
(4) toxicant exposure chamber of described gas exposure device has multiple utilitarian function, but integral disassembly, assembly, switching, moves and change, and can add foodstuff and drinking-water, can put into and take out laboratory animals such as rat, mice, does not need to separate animal fixing separately.
(5) material of the toxicant exposure chamber of described gas exposure device is clear glass, transparent plastic or IVC Mus case, but direct observation, shoots with video-corder animal situation in the toxicant exposure chamber, but sterilization can be used as disposable use equipment.
(6) gas-filtering device, filter membrane, mask can be installed in the air inlet of the toxicant exposure chamber of described gas exposure device, gas outlet, carry out gas filtration processing and preventer performance evaluation.
(7) described gas exposure device comprises that a cover is supplied gas, gas exhaust piping and corresponding joint, the chamber wall thickness ratio of described pipeline and joint was greater than 10: 1, quality is lighter than 0.5 kilogram, gas-flow resistance is less than 1000 kPas, with above-mentioned miniature air supply motor, control valve, toxicant exposure chamber with the gas sampling bag is airtight is connected, can avoid that gas leaks and secondary pollution in the device.
(8) described gas exposure device can be separately or is installed in batch on the moveable platform, connects circuit for remotely controlling, carry out repeatedly, repeatedly, for a long time, the experiment of remote gas on-site exposure to toxicant.
Description of drawings
Below in conjunction with accompanying drawing the preferred embodiment of the present invention is described.
Fig. 1 is the basic structure sketch map of gas exposure device according to the preferred embodiment of the invention.
Fig. 2 is the operation principle sketch map of gas exposure device according to the preferred embodiment of the invention.
Fig. 3 is the multi-functional sketch map of gas exposure device according to the preferred embodiment of the invention.
Among the figure, 1. gas on-site or experimental gas collecting bag, 2. air inlet pipeline, 3. miniature air supply motor, 4. barometric damper, 5. gas exposure chamber, 6. gas exhaust piping, 7. gas sampling bag, 8. toxicant exposure chamber's air inlet, 9. gas outlet, toxicant exposure chamber, 10. laboratory animal, 11. remote draught fan control circuits, 12. fixed platform, 13. observed and recorded equipment, 14. contamination chamber caps, 15. animal foodstuff and drinking-water bottle, 16. toxicant exposure chamber's interlayers, 17. protection defecators.
The specific embodiment
Fig. 1 is the basic structure sketch map of the gas exposure device of the preferred embodiment of the present invention.This device comprises an air inlet pipeline 2; One miniature air supply motor 3; One barometric damper 4; One section dismantled and assembled and mobile toxicant exposure chamber 5; Exhaustor 6 and gas sampling bag 7 that one cover combines with gas outlet, toxicant exposure chamber 9.Described aspirating pipeline 2 and exhaustor 6 and above-mentioned miniature air supply motor 3, control valve 4, toxicant exposure chamber 5 and 7 airtight connections of gas sampling bag can be avoided gas leakage and secondary pollution in the device.
Fig. 2 is the operation principle sketch map of gas exposure device according to the preferred embodiment of the invention.Its air flow direction and experiment flow are: on-the-spot air or experimental gas 1 (through collection and composition, measurement of concetration) → air inlet pipeline 2 → miniature air supply motor 3 → barometric damper 4 → intake interface (but pressure measurement speed governing/filtration treatment) → 5 → gas outlet, toxicant exposure chamber 9 (but filtration treatment) → exhaustor 6 and gas sampling bag 7 (detection).By distant control circuit 11, regulate control fan switch time and air velocity, thereby control laboratory animal 10 sucks the time and the dosage of contamination gas, keep toxicant exposure chamber's composition of gases within and concentration consistent with requirement of experiment gas or gas on-site, avoid animal to get rid of gas or the interference of other gas, help overcoming the shortcoming of existing static QI invigorating contamination device.
Fig. 3 is the multi-functional sketch map of gas exposure device according to the preferred embodiment of the invention.Toxicant exposure chamber's air inlet 8, gas outlet 9 and gas piping 4,6 are broken away from, carry out that the toxicant exposure chamber moves, replacing, sterilization; The chamber cap 14 of will contaminating is opened, and adds animal foodstuff and drinking-water 15 in the toxicant exposure chamber, or takes out laboratory animal 10; According to the experiment needs, place protection defecators 17 such as gas-filtering device, filter membrane, mask in toxicant exposure chamber's air inlet 8, gas outlet 9, protect evaluation experimental.
Claims (5)
1. miniature multifunctional gas exposure device and preparation method thereof, comprise: a miniature air supply motor, a dismantled and assembled and mobile multifunctional transparent toxicant exposure chamber, one cover connects the aspirating pipeline and the control valve of above-mentioned air supply motor and toxicant exposure chamber, exhaustor and gas sampling bag that a cover combines with the toxicant exposure chamber; This installs miniature air supply motor is made up of mini fan and control circuit thereof, by remote circuit control fan switch time and air velocity, regulates contamination time and dosage; This device gas exposure chamber is a transparent material, but integral disassembly, assembly, switching, moves and change.
2. gas exposure device as claimed in claim 1 and preparation method thereof is characterized in that, its miniature air supply motor is for there being the grade speed regulating control.
3. gas exposure device as claimed in claim 1 and preparation method thereof is characterized in that, its gas exposure chamber is transparent IVC Mus case.
4. gas exposure device as claimed in claim 1 and preparation method thereof is characterized in that, foodstuff and drinking-water can be added in its gas exposure chamber.
5. gas exposure device as claimed in claim 1 and preparation method thereof is characterized in that, gas-filtering device can be installed in its gas exposure chamber air inlet, gas outlet, carries out gas filtration processing and preventer performance evaluation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810045037A CN101536930A (en) | 2008-03-21 | 2008-03-21 | Miniature multifunctional gas exposure device and manufacturing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810045037A CN101536930A (en) | 2008-03-21 | 2008-03-21 | Miniature multifunctional gas exposure device and manufacturing method thereof |
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| Publication Number | Publication Date |
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| CN101536930A true CN101536930A (en) | 2009-09-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200810045037A Pending CN101536930A (en) | 2008-03-21 | 2008-03-21 | Miniature multifunctional gas exposure device and manufacturing method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102564949A (en) * | 2010-12-30 | 2012-07-11 | 神基科技股份有限公司 | Gas detecting system and gas detecting method |
| CN102715888A (en) * | 2012-05-28 | 2012-10-10 | 公安部四川消防研究所 | Non-destructive monitoring system for animal exposure on fire scene |
| CN107132474A (en) * | 2017-05-24 | 2017-09-05 | 国网辽宁省电力有限公司检修分公司 | SF6Killer switch experiment connection valve gear |
| CN114788498A (en) * | 2022-04-07 | 2022-07-26 | 广州医科大学附属第一医院（广州呼吸中心） | Tail gas generating device for pollutant gas exposure cabin experiment |
-
2008
- 2008-03-21 CN CN200810045037A patent/CN101536930A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102564949A (en) * | 2010-12-30 | 2012-07-11 | 神基科技股份有限公司 | Gas detecting system and gas detecting method |
| CN102564949B (en) * | 2010-12-30 | 2014-03-12 | 神基科技股份有限公司 | Gas detecting system and gas detecting method |
| CN102715888A (en) * | 2012-05-28 | 2012-10-10 | 公安部四川消防研究所 | Non-destructive monitoring system for animal exposure on fire scene |
| CN107132474A (en) * | 2017-05-24 | 2017-09-05 | 国网辽宁省电力有限公司检修分公司 | SF6Killer switch experiment connection valve gear |
| CN114788498A (en) * | 2022-04-07 | 2022-07-26 | 广州医科大学附属第一医院（广州呼吸中心） | Tail gas generating device for pollutant gas exposure cabin experiment |
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Open date: 20090923 |