CN101516902B - 多肽和其编码多聚核苷酸及它们在治疗缺血相关医学病症中的应用 - Google Patents

多肽和其编码多聚核苷酸及它们在治疗缺血相关医学病症中的应用 Download PDF

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CN101516902B
CN101516902B CN2007800358630A CN200780035863A CN101516902B CN 101516902 B CN101516902 B CN 101516902B CN 2007800358630 A CN2007800358630 A CN 2007800358630A CN 200780035863 A CN200780035863 A CN 200780035863A CN 101516902 B CN101516902 B CN 101516902B
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hif
polypeptide
nucleic acid
ischemic
ppe
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CN101516902A (zh
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E·布赖特巴特
L·班乔
R·塔尔
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Notable Labs Ltd
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Vascular Biogenics Ltd
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CN2007800358630A 2006-07-31 2007-07-31 多肽和其编码多聚核苷酸及它们在治疗缺血相关医学病症中的应用 Expired - Fee Related CN101516902B (zh)

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US83415706P 2006-07-31 2006-07-31
US60/834,157 2006-07-31
PCT/IL2007/000959 WO2008015675A2 (en) 2006-07-31 2007-07-31 Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia

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CN2012102106463A Division CN102796741A (zh) 2006-07-31 2007-07-31 多肽和其编码多核苷酸及它们在治疗缺血相关医学病症中的应用

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CN101516902A CN101516902A (zh) 2009-08-26
CN101516902B true CN101516902B (zh) 2012-08-08

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CN2012102106463A Pending CN102796741A (zh) 2006-07-31 2007-07-31 多肽和其编码多核苷酸及它们在治疗缺血相关医学病症中的应用

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US (3) US20100298226A1 (enExample)
EP (1) EP2051988A4 (enExample)
JP (2) JP5513885B2 (enExample)
KR (1) KR20090038921A (enExample)
CN (2) CN101516902B (enExample)
AU (1) AU2007280017B2 (enExample)
CA (1) CA2658972C (enExample)
MX (1) MX2009001157A (enExample)
NZ (1) NZ574410A (enExample)
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AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
EP1436313B1 (en) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
WO2008015675A2 (en) 2006-07-31 2008-02-07 Vascular Biogenics Ltd. Polypeptides and polynucleotides encoding same and use thereof in the treatment of medical conditions associated with ischemia
WO2010005527A1 (en) * 2008-06-30 2010-01-14 Angioblast Systems, Inc. Treatment of eye diseases and excessive neovascularization using a combined therapy
MX342641B (es) 2010-01-05 2016-10-07 Vascular Biogenics Ltd Metodos para uso de un agente adenoviral anti-angiogenico especifico.
MX338931B (es) 2010-01-05 2016-05-06 Vascular Biogenics Ltd Composiciones y metodo para tratar gliobastoma (gbm).
US20130052165A1 (en) * 2010-01-12 2013-02-28 Livnat Bangio Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby
WO2012052878A1 (en) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Isolated polynucleotides and nucleic acid constructs for directing expression of a gene-of-interest in cells
KR101989171B1 (ko) 2012-10-17 2019-06-14 바스큘라 바이오제닉스 리미티드 아데노바이러스를 사용하는 치료 방법
US9682154B2 (en) 2013-02-04 2017-06-20 Vascular Biogenics Ltd. Methods of inducing responsiveness to anti-angiogenic agent
WO2014144731A2 (en) * 2013-03-15 2014-09-18 The Trustees Of The University Of Pennsylvania Compositions comprising hypoxia inducible factor-1 alpha and methods of using the same
WO2015092024A2 (en) * 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
CN106046130B (zh) * 2016-07-07 2017-12-12 胡国田 一种多肽及其应用

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CN1073420A (zh) * 1991-12-18 1993-06-23 济南火柴厂 一种无硫无铬火柴的制造方法
US6124131A (en) 1998-08-25 2000-09-26 The Johns Hopkins University School Of Medicine Mutant hypoxia inducible factor-1 HIF-1
CA2418386A1 (en) * 2000-08-07 2002-02-14 Angiogenetics Sweden Ab Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the von hippel-lindau tumor suppressor protein
US7067649B2 (en) 2000-11-17 2006-06-27 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
ES2338529T3 (es) * 2000-11-17 2010-05-10 Vascular Biogenics Ltd. Prometores que exiben especificidad por celulas endoteliales y metodos para su utilizacion.
US6849718B2 (en) * 2001-03-20 2005-02-01 Dana Farber Cancer Institute, Inc. Muteins of hypoxia inducible factor alpha and methods of use thereof
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