CN101502633B - Chinese medicinal composition for treating chronic gastritis - Google Patents

Chinese medicinal composition for treating chronic gastritis Download PDF

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CN101502633B
CN101502633B CN2009100136782A CN200910013678A CN101502633B CN 101502633 B CN101502633 B CN 101502633B CN 2009100136782 A CN2009100136782 A CN 2009100136782A CN 200910013678 A CN200910013678 A CN 200910013678A CN 101502633 B CN101502633 B CN 101502633B
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白霞
赵庆华
付广文
孙国剑
王斌
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Abstract

The invention discloses a traditional Chinese medicinal composite for treating chronic gastritis, which comprises the following components according to the parts by weight: 20 to 30 parts of codonopsis pilosula, 10 to 15 parts of cassia twig, 10 to 15 parts of paenoiae alba, 10 to 15 parts of nutgrass galingale rhizome, 10 to 12 parts of turmeric root-tuber, 10 to 15 parts of sandalwood, 10 to 15 parts of combined spicebush root, 10 to 15 parts of nardostachyos root and rhizome, 10 to 15 parts of tangerine peel, 10 to 15 parts of rhizoma atractylodis macrocephalae, 10 to 15 parts of rhizoma pnelliae, 10 to 20 parts of fried immature bitter orange, 10 to 20 parts of coloured malt, 10 to 15 parts of gizzard-membrane of chicken, 9 to 10 parts of dried ginger and 5 to 6 parts of liquorice. The prescription gives prominence to the characteristics in the process of treatment of the theory of traditional Chinese medicine, has one course of the treatment for 10 to 15 days, takes effects for 1 to 3 days and can cure patients after 3 to 4 courses. The prescription is of pure natural traditional Chinese medicine, has the characteristics of little side effect and inimitable curative effect and the like, and by application and verification of 2500 clinical patients, the effective rate is up to 97.38 percent and the cure rate is up to 77 percent.

Description

A kind of Chinese medicine composition for the treatment of chronic gastritis
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic gastritis.
Background technology
Chronic gastritis means the various chronic gastric mucosa inflammatory lesion that the different causes of disease cause, is a kind of commonly encountered diseases, also is army, is engaged in night job, one of irregular person's the frequently-occurring disease of living throughout the year, and its sickness rate ranks first in various gastropathy.
Chronic gastritis changes by its histology usually and the region of anatomy is classified, be divided into following a few class: 1. superficial gastritis (superficial gastritis), inflammation only reaches the top layer epithelium of gastric mucosa, comprise rotten to the corn, hemorrhage, must to indicate be diffusivity or limitation, the latter will indicate diseased region.The body of gland of the tired mucosa depths of 2. atrophic gastritis (atrophic gastritis), inflammation also causes atrophy, as with local proliferation, claims atrophic gastritis to accompany formation (hyperplasia).3. hypertrophic gastritis (hypertrophy gastritis) claims the Enterer disease again, and significantly plump with the gastric mucosa pleat is feature as the gyrus shape, sends out well at the bottom of stomach and body of stomach, focal or diffusivity.The not bright hypoproteinemia of normal companion's reason.See gastric pits height hypertrophy under the mirror, downwardly very can reach muscular layer of mucosa.
The cause of disease of chronic gastritis and pathogeny generally have following several:
One, the sequel of acute gastritis: after the acute gastritis, gastric mucosal lesion more or does not repeatedly show effect lastingly, all can form chronic gastritis.
Two, irritable food and medicine: take the diet and the medicine that gastric mucosa there are intense stimulus for a long time, as strong tea, spirits, pungent or salicylic acid salt medicine, or when food insufficient chewing, roughage damages gastric mucosa or excessively smoking repeatedly, directly acts on due to the gastric mucosa etc. unfavorable factor.
Three, the anti-stream of duodenal juice: discovering that the chronic gastritis patient because of the sphincter of pylorus functional disorder, often causes bile reflux, may be an important paathogenic factor.
Four, immune factor: the change of immunologic function generally comes into one's own in the morbidity of chronic gastritis, atrophic gastritis, particularly body of stomach gastritis sufferer's blood, gastric juice or can find parietal cell antibody in the atrophy mucosa; Find that intrinsic factor antibody is arranged in the gastratrophia companion pernicious anemia blood samples of patients, illustrate that autoimmune response may be the relevant cause of disease of some chronic gastritis.
Five, infective agent: nineteen eighty-three Warren and Marshall find that the chronic gastritis patient has a large amount of helicobacter pylori (campylobacter pylori) to exist at the gastric antrum rete malpighii near surface epithelial cell, its positive rate has this bacterium of report not see normal gastric mucosa up to 50-80%.All this bacterium are settled down part and all see the esogastritis cellular infiltration, and the inflammation degree becomes positive correlation with bacterial number.
The clinical manifestation of chronic gastritis is:
One, superficial gastritis: chronic irregular upper abdomen dull pain, abdominal distention, belch etc. can be arranged, and obvious during especially with improper diet, part patient can have acid regurgitation, upper gastrointestinal hemorrhage.
Two, atrophic gastritis: dissimilar, its symptom of different parts is also inequality.The general symptom of digestive tract of body of stomach gastritis is less, can occur obvious anorexia sometimes, lose weight, glossitis, atrophy of tongue papillae.Gastrointestinal symptom was more obvious when atrophic gastritis influenced gastric antrum, when especially bile reflux being arranged, often show as midriff pain on the persistence, after feed, promptly go out, can be with containing biliary vomitus and retrosternal pain and burn feeling, upper gastrointestinal hemorrhage in a small amount can be arranged repeatedly sometimes, even hematemesis occurs, this is that gastric mucosal barrier wrecks and takes place due to the acute gastric mucosal erosion.
The treatment of chronic gastritis has following two kinds of approach:
One, eliminate the cause of disease: dispel various may morbific factors, as avoid taking food and gastric mucosa had the diet and the medicine of strong stimulation, smoking cessation is given up alcohol.The health that is careful in one's diet prevents eating and drinking too much at one meal.Active treatment mouth, nose, pharyngeal chronic disease.Strengthen taking exercise the raising body constitution.
Two, Drug therapy: can use atropine, probanthine, belladonna mixture, pyrenzepine etc. during the pain outbreak.Gastric hyperacidity such as gastritis verrucosa can be used cimetidine, ranitidine, aluminium hydroxide amine etc.
Although there is the medicine of multiple treatment chronic gastritis in the prior art, exist mostly therapeutic effect undesirable, can not effect a radical cure, shortcomings such as side effect is strong, the multiple complexity of therapeutic process, cost height.
Summary of the invention
At above-mentioned the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of chronic gastritis, its therapeutic effect is good, can effect a radical cure, and have no side effect, and cost is low.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition for the treatment of chronic gastritis is characterized in that, is made up of the component of following weight portion: 20~30 parts of Radix Codonopsis, 10~15 parts of Ramulus Cinnamomi, 10~15 parts of Radix Paeoniae Alba, 10~15 parts of Rhizoma Cyperis, 10~12 parts of Radix Curcumaes, 10~15 parts in Lignum Santali Albi, 10~15 parts of the Radixs Linderae, 10~15 parts of Radix Et Rhizoma Nardostachyos, 10~15 parts of Pericarpium Citri Reticulataes, 10~15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10~15 parts of Rhizoma Pinelliae, 10~20 parts of Fructus Aurantii Immaturus (parched), 10~20 parts of Fructus Hordei Germinatus (parched)s, 10~15 parts of Endothelium Corneum Gigeriae Galli, 9~10 parts of Rhizoma Zingiberiss, 5~6 parts in Radix Glycyrrhizae.
The parts by weight of described each component are: 30 parts of Radix Codonopsis, 15 parts of Ramulus Cinnamomi, 15 parts of Radix Paeoniae Alba, 15 parts of Rhizoma Cyperis, 12 parts of Radix Curcumaes, 15 parts in Lignum Santali Albi, 15 parts of the Radixs Linderae, 15 parts of Radix Et Rhizoma Nardostachyos, 15 parts of Pericarpium Citri Reticulataes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Rhizoma Pinelliae, 20 parts of Fructus Aurantii Immaturus (parched), 20 parts of Fructus Hordei Germinatus (parched)s, 15 parts of Endothelium Corneum Gigeriae Galli, 9 parts of Rhizoma Zingiberiss, 6 parts in Radix Glycyrrhizae.
The parts by weight of described each component are: 25 parts of Radix Codonopsis, 13 parts of Ramulus Cinnamomi, 13 parts of Radix Paeoniae Alba, 13 parts of Rhizoma Cyperis, 11 parts of Radix Curcumaes, 13 parts in Lignum Santali Albi, 13 parts of the Radixs Linderae, 13 parts of Radix Et Rhizoma Nardostachyos, 13 parts of Pericarpium Citri Reticulataes, 13 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 13 parts of Rhizoma Pinelliae, 13 parts of Fructus Aurantii Immaturus (parched), 15 parts of Fructus Hordei Germinatus (parched)s, 13 parts of Endothelium Corneum Gigeriae Galli, 10 parts of Rhizoma Zingiberiss, 5 parts in Radix Glycyrrhizae.
The parts by weight of described each component are: 20 parts of Radix Codonopsis, 10 parts of Ramulus Cinnamomi, 10 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Cyperis, 10 parts of Radix Curcumaes, 10 parts in Lignum Santali Albi, 10 parts of the Radixs Linderae, 10 parts of Radix Et Rhizoma Nardostachyos, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of Rhizoma Pinelliae, 10 parts of Fructus Aurantii Immaturus (parched), 10 parts of Fructus Hordei Germinatus (parched)s, 10 parts of Endothelium Corneum Gigeriae Galli, 9 parts of Rhizoma Zingiberiss, 5 parts in Radix Glycyrrhizae.
The dosage form of described Chinese medicine composition is any in tablet, powder, the capsule.
The preparation method of described Chinese medicine composition is an example with the capsule, with each dry component porphyrize powder, crosses 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Usage and consumption: oral, every day three times, each two, 10~15 days courses of treatment.
Side effect and contraindication: the clinical observation on the therapeutic effect through 20 years, patient does not have obvious toxic-side effects and takes place; Anemia of pregnant woman and allergic constitution patient forbidding.
According to China's traditional medical theory and modern medicine viewpoint, the pharmacological action of each medicine and compatibility characteristics are summarized as follows:
Radix Codonopsis: invigorating the spleen and replenishing QI, stomach function regulating promotes the production of body fluid.Has the spleen reinforcing nourishing the stomach, the effect of gas in strong the reaching.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, modern medicine study prove that this medicine has bacteriostasis widely.
Radix Paeoniae Alba: the suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation has good and stomach and alleviating pain effect.
Rhizoma Cyperi: the resolving depression of regulating the flow of vital energy, pain relieving.Modern pharmacological research proves that this medical instrument has good antibacterial and anti-inflammation functions.
Radix Curcumae: promoting QI circulation for relieving depression,, promoting blood circulation and stopping pain, with Rhizoma Cyperi, Radix Paeoniae Alba compatibility, its pain relieving stomach function regulating effect is strengthened.
Lignum Santali Albi: pleasant, it is glutted to disappear, and is mainly used in chest and abdomen swelling and pain, glutted.
The Radix Linderae: pleasant pain relieving, stomach warming are loose and are filled in, and to chest and abdomen swelling and pain person and Lignum Santali Albi compatibility, walk edema caused by disorder of QI, reach middle Jiao, activating spleen and strengthening stomach, promoting the circulation of QI to relieve pain.
Radix Et Rhizoma Nardostachyos: promoting the circulation of QI to relieve pain, the smooth stomach of being amusing, its gas fragrance with taste medicine mutually 5, holds up spleen pleasant greatly, the merit of appetite-stimulating indigestion-relieving.
Pericarpium Citri Reticulatae: in the accent of regulating the flow of vital energy, drying dampness to eliminate phlegm, but the intestinal pneumatosis is got rid of in the secretion of facilitating digestion liquid.
Rhizoma Atractylodis Macrocephalae (parched): the QI invigorating stomach reinforcing, dampness and in.Modern medicine study proves that this medicine improves significantly to gastrointestinal motility, and can improve immunity, slow down aging.
Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Fructus Aurantii Immaturus (parched): the diffusing painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy.
Fructus Hordei Germinatus (parched): help digestion and in, soothing liver-QI, with the Endothelium Corneum Gigeriae Galli compatibility the liver soothing and the spleen invigorating stomach function regulating is arranged, the effect of promoting digestion and removing stagnation intestinal stasis relieving.
Endothelium Corneum Gigeriae Galli: consumer product dredge stasis, invigorating the spleen and regulating the stomach.
Rhizoma Zingiberis: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation.
Radix Glycyrrhizae: spleen reinforcing detoxifcation, coordinating the actions of various ingredients in a prescription.
The treatment theory of the traditional Chinese medical science: chronic gastritis is modal gastropathy, belongs to sick categories such as Chinese medicine " gastric abscess ", " feeling of fullness ", " acid regurgitation ", " noisy ", " indigestion and loss of appetite ".The traditional Chinese medical science thinks that chronic gastritis is many because of feelings will is unsuccessful for a long time, eating and drinking without temperance, and work and rest is not normal, causes depression of liver-QI, dysfunction of the spleen in transportation, gastral cavilty is become estranged, and with the passing of time middle gas loses empty, thereby causes all symptoms.The dyspepsia type patient eating and drinking without temperance that injures one's stomach causes taste impaired, the food stagnation gastral cavilty, and distension painful abdominal mass pain, nausea and vomiting. belching and acid regurgitation, constipation have corrupt foreign odor, red tongue, and thick fur is yellow greasy, the pulse condition stringy and rolling pulse.Card belongs to that dyspepsia injures one's stomach, FU QI being obstructed, suitable spleen invigorating and in, digesting and appetizing.Stomach asthenic cold type patient gastral cavilty weigh down to expand and not to relax, inappetence, and acid regurgitation has a dull ache, and meets cold increasing the weight of, and must warm up then gently, and it is painful when starving that very feed subtracts slightly, loose stool, spiritlessness and weakness, there is the tooth seal on pale tongue, fat big, limit, white and thin fur, pulse condition is heavy thin and delicate or floating unable greatly.Card belongs to deficiency of QI in middle-JIAO, Deficiency and coldness of spleen and stomach, suitable invigorating the spleen and replenishing QI, spleen invigorating stomach warming.Liver-fire invading the stomach type patient is because of the prolonged illness deficiency of spleen-QI and stomach-QI, and feelings will is not relaxed, and is strongly fragrant and fire-transformation causes gastral cavilty feeling of fullness dull pain, and food back pain increases the weight of, frequent heartburn pantothenic acid, and the bitter taste stickness, the loose stool, body of the tongue is light red, yellow and greasy fur, thready and rapid pulse.Card belongs to simulataneous insufficiency and excessive, liver-fire invading the stomach.Control suitable liver-smoothing, qi-regulating, heat clearing away accent stomach.
Prescription of the present invention is according to China's theory of TCM, in conjunction with inventor's clinical research for many years, think that treatment improves the circulation of gastric blood flow with blood circulation promoting and blood stasis dispelling and solves the gastric inflammation with eliminating inflammation and expelling toxin, cooperate correct diet, make various types of gastritis by regulate the flow of vital energy and in, the foster spleen that is good for the stomach, the effect of dyspepsia and intestinal stasis relieving and reach certain therapeutic effect.The inflammation that makes stomach is in the neutralization of regulating the flow of vital energy, in spleen invigorating, support, disappear stagnate in fortune, reach the curative effect that heavy severe speed heals, the healing chronic gastritis is had the good curing effect.This prescription has been given prominence to the characteristics of theory of Chinese medical science in therapeutic process, and 10~15 days is a course of treatment, and 1~3 day takes effect, and gets final product rehabilitation 3~4 courses of treatment.This prescription is a natural Chinese medicines, and it is little to have a side effect, characteristics such as therapeutical effect uniqueness, and through clinical 2500 routine patients' application verification, effective percentage is up to 97.38%, and cure rate reaches 77%.The present invention has the following advantages: 1, pure Chinese medicinal preparation, and easy to use, no obvious toxic-side effects.2, instant effect, determined curative effect, the medicine source is extensive, and is with low cost.3, treating both the principal and secondary aspects of a disease, long-term effect is good.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment and case:
Embodiment 1: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 30 grams, Ramulus Cinnamomi 15 grams, Radix Paeoniae Alba 15 grams, Rhizoma Cyperi 15 grams, Radix Curcumae 12 grams, Lignum Santali Albi 15 grams, the Radix Linderae 15 grams, Radix Et Rhizoma Nardostachyos 15 grams, Pericarpium Citri Reticulatae 15 grams, Rhizoma Atractylodis Macrocephalae (parched) 15 grams, Rhizoma Pinelliae 15 grams, Fructus Aurantii Immaturus (parched) 20 grams, Fructus Hordei Germinatus (parched) 20 grams, Endothelium Corneum Gigeriae Galli 15 grams, Rhizoma Zingiberis 9 grams, Radix Glycyrrhizae 6 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 2: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 20 grams, Ramulus Cinnamomi 10 grams, Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 10 grams, Radix Curcumae 10 grams, Lignum Santali Albi 10 grams, the Radix Linderae 10 grams, Radix Et Rhizoma Nardostachyos 10 grams, Pericarpium Citri Reticulatae 10 grams, Rhizoma Atractylodis Macrocephalae (parched) 10 grams, Rhizoma Pinelliae 10 grams, Fructus Aurantii Immaturus (parched) 15 grams, Fructus Hordei Germinatus (parched) 15 grams, Endothelium Corneum Gigeriae Galli 12 grams, Rhizoma Zingiberis 9 grams, Radix Glycyrrhizae 6 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 3: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 25 grams, Ramulus Cinnamomi 15 grams, Radix Paeoniae Alba 15 grams, Rhizoma Cyperi 11 grams, Radix Curcumae 12 grams, Lignum Santali Albi 12 grams, the Radix Linderae 10 grams, Radix Et Rhizoma Nardostachyos 13 grams, Pericarpium Citri Reticulatae 15 grams, Rhizoma Atractylodis Macrocephalae (parched) 10 grams, Rhizoma Pinelliae 12 grams, Fructus Aurantii Immaturus (parched) 18 grams, Fructus Hordei Germinatus (parched) 20 grams, Endothelium Corneum Gigeriae Galli 13 grams, Rhizoma Zingiberis 10 grams, Radix Glycyrrhizae 5 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 4: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 30 grams, Ramulus Cinnamomi 15 grams, Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 15 grams, Radix Curcumae 11 grams, Lignum Santali Albi 12 grams, the Radix Linderae 15 grams, Radix Et Rhizoma Nardostachyos 13 grams, Pericarpium Citri Reticulatae 10 grams, Rhizoma Atractylodis Macrocephalae (parched) 13 grams, Rhizoma Pinelliae 11 grams, Fructus Aurantii Immaturus (parched) 20 grams, Fructus Hordei Germinatus (parched) 16 grams, Endothelium Corneum Gigeriae Galli 10 grams, Rhizoma Zingiberis 9 grams, Radix Glycyrrhizae 6 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 5: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 30 grams, Ramulus Cinnamomi 11 grams, Radix Paeoniae Alba 11 grams, Rhizoma Cyperi 13 grams, Radix Curcumae 15 grams, Lignum Santali Albi 15 grams, the Radix Linderae 10 grams, Radix Et Rhizoma Nardostachyos 15 grams, Pericarpium Citri Reticulatae 12 grams, Rhizoma Atractylodis Macrocephalae (parched) 12 grams, Rhizoma Pinelliae 15 grams, Fructus Aurantii Immaturus (parched) 15 grams, Fructus Hordei Germinatus (parched) 13 grams, Endothelium Corneum Gigeriae Galli 15 grams, Rhizoma Zingiberis 10 grams, Radix Glycyrrhizae 6 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 6: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 25 grams, Ramulus Cinnamomi 13 grams, Radix Paeoniae Alba 13 grams, Rhizoma Cyperi 13 grams, Radix Curcumae 11 grams, Lignum Santali Albi 13 grams, the Radix Linderae 13 grams, Radix Et Rhizoma Nardostachyos 13 grams, Pericarpium Citri Reticulatae 13 grams, Rhizoma Atractylodis Macrocephalae (parched) 13 grams, Rhizoma Pinelliae 13 grams, Fructus Aurantii Immaturus (parched) 13 grams, Fructus Hordei Germinatus (parched) 15 grams, Endothelium Corneum Gigeriae Galli 13 grams, Rhizoma Zingiberis 10 grams, Radix Glycyrrhizae 5 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Embodiment 7: prepare a kind of Chinese medicinal formulae for the treatment of chronic gastritis: get Radix Codonopsis 20 grams, Ramulus Cinnamomi 10 grams, Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 10 grams, Radix Curcumae 10 grams, Lignum Santali Albi 10 grams, the Radix Linderae 10 grams, Radix Et Rhizoma Nardostachyos 10 grams, Pericarpium Citri Reticulatae 10 grams, Rhizoma Atractylodis Macrocephalae (parched) 10 grams, Rhizoma Pinelliae 10 grams, Fructus Aurantii Immaturus (parched) 10 grams, Fructus Hordei Germinatus (parched) 10 grams, Endothelium Corneum Gigeriae Galli 10 grams, Rhizoma Zingiberis 9 grams, Radix Glycyrrhizae 5 grams, dried porphyrize powder is crossed 300 mesh sieves, and No. 1 capsule of packing into gets final product.
Clinical data:
1, data:
The case data selects have complete outpatient service data and inpatient 4930 examples year October in November, 2005-2008, is divided into treatment at random and organizes 2500 examples, matched group 2430 examples.The treatment group age is at 20~80 years old, the course of disease 1~10 year.The matched group age is at 18~79 years old, the course of disease 2~11 years.Men and women's the ratio and the course of disease are through X 2 test (P>0.05) not statistically significant.
2, Therapeutic Method: the treatment group divides 3 ante cibum oral with prescription capsule of the present invention every day, and each 2,10 days is a course of treatment.The oral motilium 10mg of matched group Tid (Xian-Janssen Pharmaceutical Ltd.'s production), ranitidine 0.15 Tid (production of Shandong Luo Xin pharmaceutcal corporation, Ltd).
3, statistical method: two groups clinical uses X 2 test, between two groups relatively, the RIDUT check, the cure rate of treatment group as a result is apparently higher than matched group, not statistically significant relatively between the total effective rate group.(seeing Table 1)
Table 1. liang group cure rate synopsis
Figure G2009100136782D00061
Annotate: P>0.001
4, side effect and contraindication:
Side effect: the clinical observation on the therapeutic effect through 20 years, patient does not have obvious toxic-side effects and takes place.
Contraindication: anemia of pregnant woman and allergic constitution patient forbidding.
Case 1: Zhang, the woman, 55 years old, the vexed bloated pain of epigastrium, belch are frequent, pantothenic acid, loss of appetite, become thin, suffer from diarrhoea 1 year surplus.After take capsule of the present invention after 5 days, pain is controlled, take 2 courses of treatment after, recover normal, with examining half a year, do not have recurrence.
Case 2: Lee so-and-so, the woman, 35 years old, the patient increased the weight of with improper diet especially because of chronic irregular upper abdomen dull pain, abdominal distention, belch, and with acid regurgitation 5 years, was examined to be superficial gastritis, the effect of throughout the year taking medicine is not good enough.After change into and take capsule of the present invention, remission after 7 days, pain disappears after 10 days, continues to take and consolidates curative effect in 2 months, does not have recurrence in 2 years with examining.
Case 3: willow so-and-so, the man, 45 years old, the patient because of on anorexia, the persistence, midriff pain, occur in feed back, and with retrosternal pain and burn feeling, lose weight, with anemia, examined and be atrophic gastritis.Through system's medical treatment, often change into after the recurrence and take capsule of the present invention, remission after 5 days, symptom complete obiteration after 20 days continues to take and consolidates curative effect 3 courses of treatment, with examining not recurrence in 2 years.
Case 4, Wang, the man, 40 years old, the patient was examined to be chronic gastritis because of the vexed bloated pain of epigastrium, belch are frequent, pantothenic acid, loss of appetite, become thin, suffer from diarrhoea and show effect 3 years repeatedly, and the effect of throughout the year taking medicine is not good enough.After change into and take capsule of the present invention, remission after 15 days, pain disappears after 20 days, continues to take and consolidates curative effect in 65 days, does not have recurrence with examining 1.5 years patients.。
Case 5, Lin, the woman, 55 years old, the patient because of repeated relapsing belch, pantothenic acid, loss of appetite, became thin 5 years, take western medicine throughout the year, effect is not good enough.After taking capsule for treating of the present invention, remission after 5 days, curative effect is consolidated in pain complete obiteration after 7 days 3 courses of treatment of continuing to take medicine, and does not have recurrence in 2 years with examining.

Claims (5)

1. a Chinese medicine composition for the treatment of chronic gastritis is characterized in that, is made up of the component of following weight portion: 20~30 parts of Radix Codonopsis, 10~15 parts of Ramulus Cinnamomi, 10~15 parts of Radix Paeoniae Alba, 10~15 parts of Rhizoma Cyperis, 10~12 parts of Radix Curcumaes, 10~15 parts in Lignum Santali Albi, 10~15 parts of the Radixs Linderae, 10~15 parts of Radix Et Rhizoma Nardostachyos, 10~15 parts of Pericarpium Citri Reticulataes, 10~15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10~15 parts of Rhizoma Pinelliae, 10~20 parts of Fructus Aurantii Immaturus (parched), 10~20 parts of Fructus Hordei Germinatus (parched)s, 10~15 parts of Endothelium Corneum Gigeriae Galli, 9~10 parts of Rhizoma Zingiberiss, 5~6 parts in Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for the treatment of chronic gastritis according to claim 1 is characterized in that the parts by weight of described each component are: 30 parts of Radix Codonopsis, 15 parts of Ramulus Cinnamomi, 15 parts of Radix Paeoniae Alba, 15 parts of Rhizoma Cyperis, 12 parts of Radix Curcumaes, 15 parts in Lignum Santali Albi, 15 parts of the Radixs Linderae, 15 parts of Radix Et Rhizoma Nardostachyos, 15 parts of Pericarpium Citri Reticulataes, 15 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 15 parts of Rhizoma Pinelliae, 20 parts of Fructus Aurantii Immaturus (parched), 20 parts of Fructus Hordei Germinatus (parched)s, 15 parts of Endothelium Corneum Gigeriae Galli, 9 parts of Rhizoma Zingiberiss, 6 parts in Radix Glycyrrhizae.
3. a kind of Chinese medicine composition for the treatment of chronic gastritis according to claim 1 is characterized in that the parts by weight of described each component are: 25 parts of Radix Codonopsis, 13 parts of Ramulus Cinnamomi, 13 parts of Radix Paeoniae Alba, 13 parts of Rhizoma Cyperis, 11 parts of Radix Curcumaes, 13 parts in Lignum Santali Albi, 13 parts of the Radixs Linderae, 13 parts of Radix Et Rhizoma Nardostachyos, 13 parts of Pericarpium Citri Reticulataes, 13 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 13 parts of Rhizoma Pinelliae, 13 parts of Fructus Aurantii Immaturus (parched), 15 parts of Fructus Hordei Germinatus (parched)s, 13 parts of Endothelium Corneum Gigeriae Galli, 10 parts of Rhizoma Zingiberiss, 5 parts in Radix Glycyrrhizae.
4. a kind of Chinese medicine composition for the treatment of chronic gastritis according to claim 1 is characterized in that the parts by weight of described each component are: 20 parts of Radix Codonopsis, 10 parts of Ramulus Cinnamomi, 10 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Cyperis, 10 parts of Radix Curcumaes, 10 parts in Lignum Santali Albi, 10 parts of the Radixs Linderae, 10 parts of Radix Et Rhizoma Nardostachyos, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10 parts of Rhizoma Pinelliae, 10 parts of Fructus Aurantii Immaturus (parched), 10 parts of Fructus Hordei Germinatus (parched)s, 10 parts of Endothelium Corneum Gigeriae Galli, 9 parts of Rhizoma Zingiberiss, 5 parts in Radix Glycyrrhizae.
5. a kind of Chinese medicine composition for the treatment of chronic gastritis according to claim 1 is characterized in that: the dosage form of described Chinese medicine composition is any in tablet, powder, the capsule.
CN2009100136782A 2009-01-23 2009-01-23 Chinese medicinal composition for treating chronic gastritis Expired - Fee Related CN101502633B (en)

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CN104547996A (en) * 2014-12-24 2015-04-29 朱梅 Traditional Chinese medicine formula for treating chronic atrophic gastritis and preparation method thereof
CN105327297A (en) * 2015-12-12 2016-02-17 张朝兰 Medicine for treating chronic gastritis and preparing method thereof
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