CN101501058B - 制备蛋白质材料的颗粒的方法 - Google Patents
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- CN101501058B CN101501058B CN200780030024.XA CN200780030024A CN101501058B CN 101501058 B CN101501058 B CN 101501058B CN 200780030024 A CN200780030024 A CN 200780030024A CN 101501058 B CN101501058 B CN 101501058B
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Images
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
反应时间/h | 平均直径/nm | 标准差/nm |
1 | 21.8 | 10.8 |
2 | 44.9 | 33.7 |
4 | 57.6 | 33.4 |
样品 | 反应时间/h | 蛋白结合MTX/mol.mol-1rHA | 平均直径/nm | 标准差/nm |
交联rHA | - | - | 48.7 | 23.4 |
MTX标记 的交联rHA | 1.5 | 12.6 | 54.2 | 26.0 |
3 | 14.4 | 58.4 | 29.5 |
样品 | 平均直径/nm | 标准差/nm |
交联rHA | 48.1 | 23.8 |
DTPA标记的交联rHA | 67.6 | 36.9 |
DTPA-Gd标记的交联rHA | 62.4 | 31.8 |
Claims (2)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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GB0613884.6 | 2006-07-13 | ||
GB0613884A GB0613884D0 (en) | 2006-07-13 | 2006-07-13 | Particles of proteinaceous material |
GB0701925.0 | 2007-02-01 | ||
GB0701925A GB0701925D0 (en) | 2007-02-01 | 2007-02-01 | Particles of proteinaceous material |
PCT/GB2007/050402 WO2008007146A1 (en) | 2006-07-13 | 2007-07-13 | Process for preparing particles of proteinaceous material |
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CN101501058A CN101501058A (zh) | 2009-08-05 |
CN101501058B true CN101501058B (zh) | 2014-05-28 |
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GB (1) | GB0613884D0 (zh) |
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KR101223484B1 (ko) | 2010-10-05 | 2013-01-17 | 한국과학기술연구원 | 사람 혈청 알부민-siRNA 나노입자 전달체 |
CN103308698B (zh) * | 2013-06-17 | 2015-04-29 | 北京北检·新创源生物技术有限公司 | 一种将含氨基的分子共价偶联至微球上的偶联方法 |
CN112569207A (zh) * | 2019-09-30 | 2021-03-30 | 复旦大学 | 一种载脂蛋白修饰的仿生纳米肿瘤疫苗及其制备方法和用途 |
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2006
- 2006-07-13 GB GB0613884A patent/GB0613884D0/en not_active Ceased
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- 2007-07-13 CN CN200780030024.XA patent/CN101501058B/zh not_active Expired - Fee Related
Non-Patent Citations (7)
Title |
---|
.1994,第272卷(第27期),17061-17069. * |
JEFFREY L. WINKELHAKE等.Protracted circulating lifetimes of mannose-terminated glycoproteins and aggregated albumin in mice infected with LDH-elevating virus.《Physiol. Chem. & Physics》.1978,第10卷305-322. |
JEFFREY L. WINKELHAKE等.Protracted circulating lifetimes of mannose-terminated glycoproteins and aggregated albumin in mice infected with LDH-elevating virus.《Physiol. Chem. & * |
Jochen kruip等.Structural organisation of the major subunits in cyanobacterial photosysterm 1.< * |
Jochen kruip等.Structural organisation of the major subunits in cyanobacterial photosysterm 1.<the journal of biological chemistry>.1994,第272卷(第27期),17061-17069. |
Physics》.1978,第10卷305-322. * |
the journal of biological chemistry> * |
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CN101501058A (zh) | 2009-08-05 |
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