CN101485841B - Health-care granule containing astragalus and coix seed - Google Patents
Health-care granule containing astragalus and coix seed Download PDFInfo
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- CN101485841B CN101485841B CN2008100592901A CN200810059290A CN101485841B CN 101485841 B CN101485841 B CN 101485841B CN 2008100592901 A CN2008100592901 A CN 2008100592901A CN 200810059290 A CN200810059290 A CN 200810059290A CN 101485841 B CN101485841 B CN 101485841B
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Abstract
The invention relates to recovery aid granules containing hoantchy root and semen coicis. A preparation method comprises the following steps: taking 10 gouts of raw materials such as hoantchy root, ginseng, semen coicis, tuckahoe, Actinidia valvata Dunn, barbed skullcap herb, paris rhizome, oldenlandia diffusa, licorice and Chinese jujube according to a definite proportion; then crushing the semen coicis from the 10 gouts of the raw materials into meal, adding petroleum ether into the meal by 1 to 3 times (in terms of weight proportion) of the amount of the semen coicis, heating and reflowingthe mixture for 0.8 to 1.2 hours at a temperature of between 60 and 90 DEG C, filtering the mixture twice, mixing the extracts, and reclaiming the petroleum ether to obtain semen coicis oil; after the extraction, adding 8 to 12 times of water into the semen coicis and the rest nine gouts of the raw materials, stirring and boiling the mixture for 0.8 to 1.2 hours, filtering the extract, and condensing the extract to have a relative density of 1.15 to 1.22 g/cm<3>; and adding the semen coicis oil and stevioside into the condensed extract, evenly mixing the mixture, spraying and drying the mixture, adding dextrin into the solid, and drying the mixture to prepare the granules. The recovery aid granules are prepared by refining, extracting and scientifically processing the pure traditional Chinese medicine, and have the efficacies of eliminating pathogens and strengthening healthy energy, tonifying qi and nourishing the blood.
Description
Technical field
The present invention relates to a kind of pharmaceutical products, is a kind of Chinese medicine preparation with effect of eliminating pathogenic factor for supporting vital QI, benefiting QI and nourishing blood.
Background technology
Cancer is that a kind of incidence rate height, treatment are difficult, the cellularity disease of prognosis weak effect, and its pathogeny is extremely complicated, one of global refractory main difficult and complicated illness.At present, main treatment means has surgical operation therapy, chemical drugs therapy, radiation therapy, immunization therapy and traditional Chinese medicine both at home and abroad.Therefore further but still do not have a kind of ideal medicine or method can thoroughly effect a radical cure cancer so far, the new cancer treatment drugs of developmental research is very necessary.
Summary of the invention
The stilbene heart of a lotus seed that primary technical problem to be solved by this invention provides a kind of eliminating pathogenic factor for supporting vital QI, benefiting QI and nourishing blood effect helps recovering particles, and this medicine is oral to have certain tumor-inhibiting action, and can strengthen the antineoplastic immune function, share with chemotherapeutic to have the efficacy enhancing and toxicity reducing effect.
The present invention solves the problems of the technologies described above the technical scheme that is adopted: a kind of stilbene heart of a lotus seed helps recovering particles, it is characterized in that making particulate raw material of Chinese medicine prescription to be:
Radix Astragali 500-700 Radix Ginseng 150-350 Semen Coicis 800-1000
Poria 350-550 Radix actinidiae valvatae 800-1000 Herba Scutellariae Barbatae 200-400
Rhizoma Paridis 350-550 Herba Hedyotidis Diffusae 350-550 Radix Glycyrrhizae 100-300
Fructus Jujubae 350-550
Above component is benchmark with parts by weight.
As preferably, the prescription of its raw material of Chinese medicine:
The Radix Astragali 610 Radix Ginsengs 244 Semen Coiciss 915
Poria 457 Radix actinidiae valvataes 915 Herba Scutellariae Barbataes 305
Rhizoma Paridis 457 Herba Hedyotidis Diffusaes 457 Radix Glycyrrhizaes 183
Fructus Jujubae 457.
Final granule also contains 0.1～0.5% stevioside, is weight percentage.
Compared with prior art, the invention has the advantages that:
The stilbene heart of a lotus seed helps recovering particles " with 10 kinds of raw materials such as the Radix Astragali, Radix Ginseng, Semen Coicis, Poria, Radix actinidiae valvatae, Herba Scutellariae Barbatae, Rhizoma Paridis, Herba Hedyotidis Diffusae, Radix Glycyrrhizae, Fructus Jujubaes, form by a certain percentage.This medicine adopts pure Chinese medicine, refining refinement, science to process.Specify unit testing through country, this medicine is oral to have certain tumor-inhibiting action, and can strengthen the antineoplastic immune function of mice with tumor, share with chemotherapeutic to have the efficacy enhancing and toxicity reducing effect.
" the stilbene heart of a lotus seed helps recovering particles " prescription mainly is because weakened body resistance, scorchingly hot and stagnation of phlegm combines in line with strengthening vital QI to eliminate pathogenic factors in view of the generation of cancer according to Chinese medicine, follows the example of invigorating the spleen and benefiting QI, with solid Central Region.The key medicine Radix Astragali, Radix Ginseng with the spleen invigorating of nourishing blood serve as main, be equipped with heat-clearing and toxic substances removing, eight flavor Chinese medicines such as the Semen Coicis of functions such as benefiting QI and nourishing blood, Poria, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix actinidiae valvatae, Rhizoma Paridis, Radix Glycyrrhizae, Fructus Jujubae, the granule that adopts modern crafts to extract, process, can treat gastrointestinal cancer effectively, promote the rehabilitation behind cancer patient's operation, the chemicotherapy, it is painful and not feel at ease to remove cancer patient's health, improve the quality of living life-saving.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail.
Examples of implementation 1
The prescription of raw material of Chinese medicine:
The Radix Astragali 610 Radix Ginsengs 244 Semen Coiciss 915
Poria 457 Radix actinidiae valvataes 915 Herba Scutellariae Barbataes 305
Rhizoma Paridis 457 Herba Hedyotidis Diffusaes 457 Radix Glycyrrhizaes 183
Fructus Jujubae 457
With parts by weight is benchmark.
Form by a certain percentage.With above ten flavors, get Semen Coicis powder and be broken into coarse powder then, the ratio of doubly measuring (part by weight) with Semen Coicis quantity 1-3 adds petroleum ether, under 60-90 ℃, and reflux 0.8～1.2 hour, twice filtration, merge extractive liquid, reclaims petroleum ether, gets Semen Coicis oil; Extract the back Semen Coicis and doubly measure (part by weight) ratio and add entry, stir and boiled 0.8～1.2 hour with all the other nine 8-12 that distinguish the flavor of in addition, the extracting solution filtration, being concentrated into relative density is 1.15-1.22g/cm
3Add above-mentioned Semen Coicis oil and stevioside, mixing, spray drying, solid adds dextrin, and dry type is made granule and is got.
Concrete grammar is:
Getting above ten flavor gross weights is 5000g, gets Semen Coicis powder and is broken into coarse powder, adds 1830ml petroleum ether (60-90 ℃), reflux 1 hour, and twice filtration, merge extractive liquid, reclaims petroleum ether, gets Semen Coicis oil.Extraction back Semen Coicis and all the other nine flavors add the stirring of 50 premium on currency and boiled 1 hour, and extracting solution filters, and being concentrated into relative density is 1.15-1.22g/cm
3, add above-mentioned Semen Coicis oil and 3 gram steviosides, mixing, spray drying, solid adds dextrin to 1000 gram, and dry granulation is distributed into 100 bags, promptly.
Oral each 10 grams, 3 times on the one was a course of treatment with 42 days.
The stilbene heart of a lotus seed helps recovering particles effect example
Pharmacological testing: high, medium and low dosage group (2.5g/kg, 1.25g/kg, 0.63g/kg)
1, eliminating evil effect
(1) to transplanting Lewis lung cancer inhibitory action (three tests are to the heavy suppression ratio of tumor):
| Sequence number | High dose group | Middle dosage group | Low dose group |
| 1 | 49.8％ | 46.2％ | 42.2％ |
| 2 | 42.9％ | 38.5％ | 30.0％ |
| 3 | 46.9％ | 42.0％ | 32.4％ |
(2) mice is transplanted melanin tumour b16 effect (three tests are to the heavy suppression ratio of tumor):
| Sequence number | High dose group | Middle dosage group | Low dose group |
| 1 | 42.4％ | 40.7％ | 29.0％ |
| 2 | 51.2％ | 46.9％ | 43.1％ |
| 3 | 41.7％ | 50.1％ | 36.9％ |
(2) to rat watt gram tumor (sarcoma) W256 effect (three tests are to the heavy suppression ratio of tumor):
| Sequence number | High dose group | Middle dosage group | Low dose group |
| 1 | 42.4％ | 40.7％ | 29.0％ |
| 2 | 51.2％ | 46.9％ | 43.1％ |
| 3 | 41.7％ | 50.1％ | 36.9％ |
2, centralizing function:
(1) mononuclear phagocyte to mice has activation, can increase the content of serum lysozyme: value added is: 36.50ug/ml 37.62ug/ml 32.62ug/ml 39.84ug/ml 34.88ug/ml 35.40ug/ml.
(2) generation has immunological enhancement to specific antibody, and the antiserum cytotoxic activity is: 1.98 2.09 1.99 2.031.85 1.91.
Examples of implementation 2
The prescription of raw material of Chinese medicine:
The Radix Astragali 700 Radix Ginsengs 350 Semen Coiciss 1000
Poria 550 Radix actinidiae valvataes 1000 Herba Scutellariae Barbataes 400
Rhizoma Paridis 550 Herba Hedyotidis Diffusaes 550 Radix Glycyrrhizaes 300
Fructus Jujubae 550
With parts by weight is benchmark.
Getting above ten flavor gross weights is 5950g, more than ten flavors, get Semen Coicis powder and be broken into coarse powder, add 2000ml petroleum ether (60-90 ℃), reflux 1 hour, twice filtration, merge extractive liquid, reclaims petroleum ether, Semen Coicis oil.Extraction back Semen Coicis and all the other nine flavors add the stirring of 60 premium on currency and boiled 1 hour, and extracting solution filters, and being concentrated into relative density is 1.15-1.22g/cm
3, add above-mentioned Semen Coicis oil and 4 gram steviosides, mixing, spray drying, solid adds dextrin to 1200 gram, and dry granulation is distributed into 120 bags, promptly.
Oral each 10 grams, 3 times on the one was a course of treatment with 42 days.
Examples of implementation 3
The Radix Astragali 500 Radix Ginsengs 150 Semen Coiciss 800
Poria 350 Radix actinidiae valvataes 800 Herba Scutellariae Barbataes 200
Rhizoma Paridis 350 Herba Hedyotidis Diffusaes 350 Radix Glycyrrhizaes 100
Fructus Jujubae 350
With parts by weight is benchmark.
Getting above ten flavor gross weights is 3950g, gets Semen Coicis powder and is broken into coarse powder, adds 1600ml petroleum ether (60-90 ℃), reflux 1 hour, and twice filtration, merge extractive liquid, reclaims petroleum ether, gets Semen Coicis oil.Extraction back Semen Coicis and all the other nine flavors add the stirring of 40 premium on currency and boiled 1 hour, and extracting solution filters, and being concentrated into relative density is 1.15-1.22g/cm
3, add above-mentioned Semen Coicis oil and 3 gram steviosides, mixing, spray drying, solid adds dextrin to 800 gram, and dry granulation is distributed into 80 bags, promptly.
Oral each 10 grams, 3 times on the one was a course of treatment with 42 days.
Claims (3)
1. a stilbene heart of a lotus seed helps recovering particles, it is characterized in that making particulate raw material of Chinese medicine prescription to be:
Radix Astragali 500-700 Radix Ginseng 150-350 Semen Coicis 800-1000
Poria 350-550 Radix actinidiae valvatae 800-1000 Herba Scutellariae Barbatae 200-400
Rhizoma Paridis 350-550 Herba Hedyotidis Diffusae 350-550 Radix Glycyrrhizae 100-300
Fructus Jujubae 350-550
Above component is benchmark with parts by weight.
2. the stilbene heart of a lotus seed according to claim 1 helps recovering particles, it is characterized in that the prescription of raw material of Chinese medicine:
The Radix Astragali 610 Radix Ginsengs 244 Semen Coiciss 915
Poria 457 Radix actinidiae valvataes 915 Herba Scutellariae Barbataes 305
Rhizoma Paridis 457 Herba Hedyotidis Diffusaes 457 Radix Glycyrrhizaes 183
Fructus Jujubae 457.
3. the stilbene heart of a lotus seed according to claim 1 and 2 helps recovering particles, it is characterized in that granule also contains 0.1～0.5% stevioside, is weight percentage.
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| CN101485841B true CN101485841B (en) | 2011-05-04 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105362801A (en) * | 2014-08-28 | 2016-03-02 | 李华 | Traditional Chinese medicine for treating cancer |
| CN108355014A (en) * | 2018-05-23 | 2018-08-03 | 北京雄九医学研究院 | Anticancer traditional Chinese medicinal composition |
| CN108434304A (en) * | 2018-05-23 | 2018-08-24 | 北京雄九医学研究院 | The preparation method of cancer-resisting Chinese medicine |
| CN110193050A (en) * | 2019-07-09 | 2019-09-03 | 河南省中医院（河南中医药大学第二附属医院） | Traditional Chinese medicine composition for preventing recurrence and metastasis of digestive tract tumor and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225209C (en) * | 2003-07-28 | 2005-11-02 | 郑伟达 | Health food for cancer patient and preparing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1225209C (en) * | 2003-07-28 | 2005-11-02 | 郑伟达 | Health food for cancer patient and preparing method thereof |
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