CN101479325B - 可聚合的硅氧烷-季胺共聚物 - Google Patents
可聚合的硅氧烷-季胺共聚物 Download PDFInfo
- Publication number
- CN101479325B CN101479325B CN200780023604.6A CN200780023604A CN101479325B CN 101479325 B CN101479325 B CN 101479325B CN 200780023604 A CN200780023604 A CN 200780023604A CN 101479325 B CN101479325 B CN 101479325B
- Authority
- CN
- China
- Prior art keywords
- monomer
- unsubstituted
- group
- replace
- medical device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/452—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Silicon Polymers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/479,608 US7468397B2 (en) | 2006-06-30 | 2006-06-30 | Polymerizable siloxane-quaternary amine copolymers |
| US11/479,608 | 2006-06-30 | ||
| PCT/US2007/070509 WO2008005644A1 (en) | 2006-06-30 | 2007-06-06 | Polymerizable siloxane-quaternary amine copolymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101479325A CN101479325A (zh) | 2009-07-08 |
| CN101479325B true CN101479325B (zh) | 2013-06-26 |
Family
ID=38657660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780023604.6A Expired - Fee Related CN101479325B (zh) | 2006-06-30 | 2007-06-06 | 可聚合的硅氧烷-季胺共聚物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7468397B2 (https=) |
| EP (2) | EP2035486B1 (https=) |
| JP (1) | JP5519277B2 (https=) |
| CN (1) | CN101479325B (https=) |
| AT (1) | ATE555150T1 (https=) |
| BR (1) | BRPI0712367A2 (https=) |
| CA (1) | CA2652075A1 (https=) |
| ES (2) | ES2428273T3 (https=) |
| WO (1) | WO2008005644A1 (https=) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
| JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8277713B2 (en) * | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
| US8989833B2 (en) * | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
| US7771833B2 (en) * | 2005-05-09 | 2010-08-10 | Ndsu Research Foundation | Anti-fouling materials containing cationic polysiloxanes |
| US7759408B2 (en) * | 2005-12-21 | 2010-07-20 | Bausch & Lomb Incorporated | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups |
| US8828420B2 (en) * | 2006-01-06 | 2014-09-09 | Bausch & Lomb Incorporated | Siloxane prepolymer containing pendant cationic and polymerizable groups |
| US7825273B2 (en) * | 2006-01-06 | 2010-11-02 | Bausch & Lomb Incorporated | Process for making cationic hydrophilic siloxanyl monomers |
| US7960447B2 (en) | 2006-04-13 | 2011-06-14 | Bausch & Lomb Incorporated | Cationic end-capped siloxane prepolymer for reduced cross-link density |
| WO2007120381A2 (en) * | 2006-04-14 | 2007-10-25 | Dexcom, Inc. | Analyte sensor |
| US8105623B2 (en) * | 2006-06-30 | 2012-01-31 | Bausch & Lomb Incorporated | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups |
| US7579021B2 (en) * | 2006-09-27 | 2009-08-25 | Bausch & Lomb Incorporated | Drug delivery systems based on degradable cationic siloxanyl macromonomers |
| US7781558B2 (en) * | 2006-09-27 | 2010-08-24 | Bausch & Lomb Incorporated | Hydrophilic siloxanyl monomers with pendant polymerizable groups |
| US8372384B2 (en) * | 2007-01-08 | 2013-02-12 | Ndsu Research Foundation | Quaternary ammonium functionalized cross-linked polyalkylsiloxanes with anti-fouling activity |
| US7951897B2 (en) * | 2007-01-26 | 2011-05-31 | Bausch & Lomb Incorporated | Synthesis of cationic siloxane prepolymers |
| US8709394B2 (en) * | 2007-09-28 | 2014-04-29 | Ndsu Research Foundation | Antimicrobial polysiloxane materials containing metal species |
| US20100004202A1 (en) * | 2008-02-15 | 2010-01-07 | Ndsu Research Foundation | Quaternary ammonium-functionalized-POSS compounds |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US20090247855A1 (en) * | 2008-03-28 | 2009-10-01 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8093352B2 (en) * | 2008-08-05 | 2012-01-10 | Alcon Research, Ltd. | Polyalkylene oxide polyquaternary ammonium biocides |
| US8560039B2 (en) | 2008-09-19 | 2013-10-15 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
| US20110212994A1 (en) | 2009-06-26 | 2011-09-01 | Brian Clem | Small Molecule Choline Kinase Inhibitors, Screening Assays, and Methods for Safe and Effective Treatment of Neoplastic Disorders |
| AU2011282603B2 (en) | 2010-07-30 | 2014-01-30 | Novartis Ag | Amphiphilic polysiloxane prepolymers and uses thereof |
| US8835525B2 (en) | 2010-10-06 | 2014-09-16 | Novartis Ag | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains |
| EP2625216B1 (en) | 2010-10-06 | 2019-06-05 | Novartis AG | Polymerisable chain-extended polysiloxanes with pendant hydrophilic groups |
| CN103168067B (zh) | 2010-10-06 | 2015-08-05 | 诺华股份有限公司 | 可水处理的含硅氧烷预聚物及其用途 |
| EP2951242B1 (en) | 2013-01-31 | 2019-09-11 | Momentive Performance Materials Inc. | Water soluble silicone material |
| US9486311B2 (en) | 2013-02-14 | 2016-11-08 | Shifamed Holdings, Llc | Hydrophilic AIOL with bonding |
| CA3193600A1 (en) | 2013-03-21 | 2014-09-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| US10195018B2 (en) | 2013-03-21 | 2019-02-05 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| AU2015306613B2 (en) | 2014-08-26 | 2018-01-25 | Shifamed Holdings, Llc | Accommodating intraocular lens |
| US9976974B2 (en) * | 2015-01-27 | 2018-05-22 | University Of Utah Research Foundation | Osmolarity-responsive hydrogel sensors and method of use |
| US11141263B2 (en) | 2015-11-18 | 2021-10-12 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lens |
| JP6934197B2 (ja) | 2015-11-18 | 2021-09-15 | シファメド・ホールディングス・エルエルシー | 複数片の調節式眼内レンズ |
| CN120000379A (zh) | 2016-12-23 | 2025-05-16 | 施菲姆德控股有限责任公司 | 多片式调节性人工晶状体及其制造和使用方法 |
| US10350056B2 (en) | 2016-12-23 | 2019-07-16 | Shifamed Holdings, Llc | Multi-piece accommodating intraocular lenses and methods for making and using same |
| US11254789B2 (en) * | 2017-02-16 | 2022-02-22 | Momentive Performance Materials Inc. | Ionically modified silicones, compositions, and medical devices formed therefrom |
| CN110996848B (zh) | 2017-05-30 | 2023-08-04 | 施菲姆德控股有限责任公司 | 调节性人工晶状体的表面处理以及相关方法和装置 |
| EP4205702B1 (en) | 2017-06-07 | 2025-09-10 | Shifamed Holdings, LLC | Adjustable optical power intraocular lenses |
| EP3996629A4 (en) | 2019-07-11 | 2023-08-09 | Shifamed Holdings, LLC | ACCOMMODATING INTRAOCULAR LENSES AND RELATED PROCEDURES |
| CN119998361A (zh) * | 2022-06-02 | 2025-05-13 | 迈图高新材料公司 | 聚硅氧烷聚合物组合物及其制备方法 |
| JP2025009290A (ja) | 2023-07-07 | 2025-01-20 | 信越化学工業株式会社 | 分子鎖中に第3級アミノ基を有するオルガノポリシロキサンおよびその製造方法 |
| JP2025009288A (ja) | 2023-07-07 | 2025-01-20 | 信越化学工業株式会社 | 分子鎖中に第3級アミノ基または第4級アンモニウムカチオン部位を有する両末端(メタ)アクリル変性シリコーンマクロマーおよびその製造方法 |
| JP2025009289A (ja) | 2023-07-07 | 2025-01-20 | 信越化学工業株式会社 | 分子鎖中に第3級アミノ基を有するオルガノポリシロキサンおよびその製造方法 |
| WO2025215096A1 (en) * | 2024-04-11 | 2025-10-16 | Bausch + Lomb Ireland Limited | Silicone contact lens-forming prepolymer and silicone contact lens formed therefrom |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0820601B1 (en) * | 1995-04-04 | 1999-12-22 | Novartis AG | Polysiloxane-comprising perfluoroalkyl ethers, and the preparation and use thereof |
| US6043328A (en) * | 1995-05-19 | 2000-03-28 | Novartis Ag | Polysiloxane-polyol macromers, their preparation and their use |
| CN1373794A (zh) * | 1999-07-27 | 2002-10-09 | 博士伦公司 | 接触镜片材料 |
| EP1285943A2 (de) * | 2001-08-23 | 2003-02-26 | Goldschmidt AG | UV-Licht absorbierende quartäre Polysiloxane |
| CN1643033A (zh) * | 2002-03-20 | 2005-07-20 | 博士伦公司 | 一种制备用于医疗器械的聚硅氧烷基聚合组合物的改进方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539016A (en) | 1967-09-28 | 1970-11-10 | Clark Equipment Co | Actuating means for foldable implement carriage |
| US3734763A (en) * | 1969-05-15 | 1973-05-22 | Dow Corning | Cationic unsaturated amine-functional silane coupling agents |
| US3808179A (en) * | 1972-06-16 | 1974-04-30 | Polycon Laboratories | Oxygen-permeable contact lens composition,methods and article of manufacture |
| US3843529A (en) * | 1972-08-10 | 1974-10-22 | Dow Corning | Metal working lubricant compositions |
| US3884886A (en) * | 1973-01-15 | 1975-05-20 | Dow Corning | Cationic unsaturated amine-functional silane coupling agents |
| US4153641A (en) * | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
| US4260725A (en) * | 1979-12-10 | 1981-04-07 | Bausch & Lomb Incorporated | Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains |
| US4463149A (en) * | 1982-03-29 | 1984-07-31 | Polymer Technology Corporation | Silicone-containing contact lens material and contact lenses made thereof |
| DE3601742A1 (de) * | 1985-06-13 | 1987-07-23 | Merck Patent Gmbh | Organosiliciumverbindungen |
| US5594089A (en) | 1985-09-05 | 1997-01-14 | The Boeing Company | Heterocycle or heterocycle sulfone oligomers with multiple chemically functional end caps |
| US4686267A (en) * | 1985-10-11 | 1987-08-11 | Polymer Technology Corporation | Fluorine containing polymeric compositions useful in contact lenses |
| DE3719086C1 (de) * | 1987-06-06 | 1988-10-27 | Goldschmidt Ag Th | Diquartaere Polysiloxane,deren Herstellung und Verwendung in kosmetischen Zubereitungen |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070215A (en) * | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5034461A (en) * | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
| US5358995A (en) * | 1992-05-15 | 1994-10-25 | Bausch & Lomb Incorporated | Surface wettable silicone hydrogels |
| TW243455B (https=) * | 1993-02-09 | 1995-03-21 | Ciba Geigy | |
| US5321108A (en) * | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
| US5374662A (en) * | 1993-03-15 | 1994-12-20 | Bausch & Lomb Incorporated | Fumarate and fumaramide siloxane hydrogel compositions |
| FR2708199B1 (fr) * | 1993-07-28 | 1995-09-01 | Oreal | Nouvelles compositions cosmétiques et utilisations. |
| US5451651A (en) * | 1993-12-17 | 1995-09-19 | Bausch & Lomb Incorporated | Urea and urethane monomers for contact lens materials |
| US5760100B1 (en) * | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| US6359024B2 (en) * | 1998-05-15 | 2002-03-19 | Bausch & Lomb Incorporated | Method for polymerizing contact lenses |
| US6444776B1 (en) * | 1998-12-21 | 2002-09-03 | Novartis Ag | Organic polymers |
| ATE441132T1 (de) * | 1999-12-16 | 2009-09-15 | Asahikasei Aime Co Ltd | Zum tragen über lange zeiträume geeignete weiche kontaktlinsen |
| US6599559B1 (en) * | 2000-04-03 | 2003-07-29 | Bausch & Lomb Incorporated | Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers |
| DE10051258A1 (de) * | 2000-10-16 | 2002-04-25 | Goldschmidt Rewo Gmbh & Co Kg | Verwendung von quaternären Polysiloxanen in Waschmittelformulierungen |
| US6774178B2 (en) * | 2001-01-05 | 2004-08-10 | Novartis Ag | Tinted, high Dk ophthalmic molding and a method for making same |
| US7411029B2 (en) * | 2004-06-25 | 2008-08-12 | Bausch & Lomb Incorporated | Prepolymers for improved surface modification of contact lenses |
| US7622512B2 (en) * | 2005-12-21 | 2009-11-24 | Bausch & Lomb Incorporated | Cationic hydrophilic siloxanyl monomers |
| US7759408B2 (en) * | 2005-12-21 | 2010-07-20 | Bausch & Lomb Incorporated | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups |
| US7960447B2 (en) * | 2006-04-13 | 2011-06-14 | Bausch & Lomb Incorporated | Cationic end-capped siloxane prepolymer for reduced cross-link density |
-
2006
- 2006-06-30 US US11/479,608 patent/US7468397B2/en not_active Expired - Fee Related
-
2007
- 2007-06-06 EP EP07798170A patent/EP2035486B1/en not_active Not-in-force
- 2007-06-06 AT AT07798170T patent/ATE555150T1/de active
- 2007-06-06 CN CN200780023604.6A patent/CN101479325B/zh not_active Expired - Fee Related
- 2007-06-06 CA CA002652075A patent/CA2652075A1/en not_active Abandoned
- 2007-06-06 ES ES11177006T patent/ES2428273T3/es active Active
- 2007-06-06 WO PCT/US2007/070509 patent/WO2008005644A1/en not_active Ceased
- 2007-06-06 ES ES07798170T patent/ES2382863T3/es active Active
- 2007-06-06 EP EP11177006.1A patent/EP2404951B1/en not_active Not-in-force
- 2007-06-06 JP JP2009518430A patent/JP5519277B2/ja not_active Expired - Fee Related
- 2007-06-06 BR BRPI0712367-1A patent/BRPI0712367A2/pt not_active Application Discontinuation
-
2008
- 2008-11-18 US US12/313,253 patent/US20090143556A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0820601B1 (en) * | 1995-04-04 | 1999-12-22 | Novartis AG | Polysiloxane-comprising perfluoroalkyl ethers, and the preparation and use thereof |
| US6043328A (en) * | 1995-05-19 | 2000-03-28 | Novartis Ag | Polysiloxane-polyol macromers, their preparation and their use |
| CN1373794A (zh) * | 1999-07-27 | 2002-10-09 | 博士伦公司 | 接触镜片材料 |
| EP1285943A2 (de) * | 2001-08-23 | 2003-02-26 | Goldschmidt AG | UV-Licht absorbierende quartäre Polysiloxane |
| CN1643033A (zh) * | 2002-03-20 | 2005-07-20 | 博士伦公司 | 一种制备用于医疗器械的聚硅氧烷基聚合组合物的改进方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2035486A1 (en) | 2009-03-18 |
| HK1164348A1 (en) | 2012-09-21 |
| ES2428273T3 (es) | 2013-11-06 |
| JP2009542855A (ja) | 2009-12-03 |
| US20090143556A1 (en) | 2009-06-04 |
| CA2652075A1 (en) | 2008-01-10 |
| EP2035486B1 (en) | 2012-04-25 |
| US7468397B2 (en) | 2008-12-23 |
| BRPI0712367A2 (pt) | 2012-06-05 |
| EP2404951B1 (en) | 2013-09-11 |
| ATE555150T1 (de) | 2012-05-15 |
| JP5519277B2 (ja) | 2014-06-11 |
| EP2404951A1 (en) | 2012-01-11 |
| HK1127621A1 (en) | 2009-10-02 |
| ES2382863T3 (es) | 2012-06-14 |
| CN101479325A (zh) | 2009-07-08 |
| US20080001318A1 (en) | 2008-01-03 |
| WO2008005644A1 (en) | 2008-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130626 Termination date: 20190606 |