CN101461379A - Composite lysozyme disinfecting liquid - Google Patents
Composite lysozyme disinfecting liquid Download PDFInfo
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- CN101461379A CN101461379A CNA2007101157202A CN200710115720A CN101461379A CN 101461379 A CN101461379 A CN 101461379A CN A2007101157202 A CNA2007101157202 A CN A2007101157202A CN 200710115720 A CN200710115720 A CN 200710115720A CN 101461379 A CN101461379 A CN 101461379A
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- lysozyme
- bacilli
- bactericidal
- disinfecting liquid
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Abstract
The invention relates to a complex lysozyme disinfectant, which is prepared by lysozyme and poly hexamethylene guanidine as a prescription system. The lysozyme enables bacilli or yeast to be dissolved with fungal cell wall, causing animalcule to die. Non-enzymatic solubilization of lysozyme products is the key factor of sterilization. Lysozyme still keeps bactericidal action after being heated and inactivated, which shows presence of non-enzymatic bactericidal action. Lysozyme can cooperate with a plurality of factors, thereby widening bactericidal spectrum and enhancing bactericidal potency. Poly hexamethylene guanidine has high activity, has strong compatibility to animalcule, so is easily adsorbed by all kinds of bacilli, fungi and virus with electronegativity, and is fast penetrated into bacterial cells, causes protein in the cells to freeze and denaturalize, thereby restraining fissiparity function. Through the synergistic disinfecting action of each component, main components-peptidoglycan and lipoprotein of all kinds of bacilli, fungi and virus cell walls are fast cracked, activity of lipoxygenase and epoxidase of bacilli is restrained, causing energy required for growth, propagation metabolize obtained through biooxidation to be damaged, basic vital activity of bacilli stops, thereby reaching bactericidal action.
Description
Technical field the present invention relates to a kind of composite lysozyme disinfecting liquid, and especially effectively sterilization component lysozyme, polyhexamethylene guanide are as the composite lysozyme disinfecting liquid of formula system.Composite lysozyme disinfecting liquid can be used for the antibiotic and sterilizing of various industries, every field, various article.Existing antibiotic and sterilizing product variety is a lot, and the antibiotic and sterilizing performance differs, and the branch of high, medium and low effect is arranged.The active ingredient of high effect disinfectants and content are directly proportional with price often; And toxic, corrosivity, penetrating odor have pollution to environment, to being sterilized article certain damage are arranged.Therefore, every profession and trade is wished that always a kind of antibiotic and sterilizing efficient height can be arranged, safety and stability, environmentally safe, article is not had the compound bio enzyme disinfecting liquid of damage.
Background technology the object of the present invention is to provide a kind of composite lysozyme antibiotic and sterilizing product that can overcome the existing procucts deficiency; Belong to the green compound bio enzyme product that nontoxic, tasteless, non-stimulated, no burn into does not have allergy, has no side effect, it is good to have a Disinfection Effect, keeps skin normal physiological environment, environment is not polluted absorption naturally, characteristics such as safety and stability.
Summary of the invention main points of the present invention are to select suitable component, and rationally prepare, through a kind of composite lysozyme disinfecting liquid that purifies, rationally is mixed, emulsion reaction forms.
The prescription following (component and percentage by weight % thereof) that the present invention selects: lysozyme 5.0-10.0; Polyhexamethylene guanide 0.5-0.8; Deionized water adds to 100.
Lysozyme can make bacterium or yeast and fungal cell wall dissolving, causes microbial death.The molten effect of non-enzyme of lysozyme product is that it kills one of principal element of bacterium.Lysozyme still can keep its bactericidal action after heated and inactivated, show the existence of non-enzyme and sterilizing effect.Lysozyme can be collaborative with the multiple factor, widens fungicidal spectrum, strengthens bactericidal potency.
Polyhexamethylene guanide has very high activity, microorganism there is very strong compatibility, so be easy to be usually electronegative each bacterioid, fungi, viral adsorbed, penetrate in the bacterial cell all sidedly fast, thereby make intracellular protein coagulating sex change suppress their schizogamy function.Crack the main component of each bacterioid, fungi, virocyte wall---peptide glycan and lipoprotein rapidly by the concurrent disinfection interaction energy of above-mentioned each component, and can suppress the activity of lipoxygenase and the epoxidase of bacterium, the required energy that bacterial growth, breeding, metabolism are obtained by biological oxidation is destroyed, the basic vital movement of bacterium stops, and reaches bactericidal action.
The preparation method of product of the present invention is:
1) by proportioning described component lysozyme is purified, rationally is mixed and carries out emulsion reaction again.
2) by proportioning described polyhexamethylene guanide is joined in the above-mentioned emulsion, stir, packing after sterilization is chilled to 30-40 ℃.
The present invention compares with existing disinfectant has following advantage: (1) sterilization effect is remarkable, keeps skin normal physiological environment, absorbs naturally; (2) nontoxic, non-stimulated, do not have an irritated non-corrosiveness.The green compound bio enzyme product that has no side effect.
(3) scope of application is wide, is suitable for the sterilization of every field personnel decontamination.(4) this product is the compound biological enzyme disinfectant, and chemical property is very stable, the term of validity 2 years.(5) fast volatilization leaves no trace, sterilization dispel flavor, carry, convenient and practical (6) technology is simple, cost is low.
The present invention is described in further detail below in conjunction with embodiment for embodiment:
Be configured according to listed data of following table (percentage by weight %) and affiliated step thereof: tables of data:
Prescription one:
Lysozyme 5.0-10.0
Polyhexamethylene guanide 0.5-0.8
Deionized water adds to 100
-------------------------------------------------------
Prescription two:
Lysozyme 6.0-10.0
Polyhexamethylene guanide 0.6-0.8
Deionized water adds to 100
-------------------------------------------------------
Prescription three:
Lysozyme 5.0-8.0
Polyhexamethylene guanide 0.5-0.7
Deionized water adds to 100
------------------------------------------------------
Prescription four:
Lysozyme 6.0-8.0
Polyhexamethylene guanide 0.6-0.7
Deionized water adds to 100.
-------------------------------------------------------
Claims (2)
- One kind with lysozyme, polyhexamethylene guanide as formula system, rationally be mixed in proportion, through a kind of composite lysozyme disinfecting liquid that purifies, rationally is mixed, emulsion reaction forms; It is characterized in that having following prescription (component and percentage by weight % thereof): lysozyme 10.0-20.0; Polyhexamethylene guanide 0.5-0.8; Deionized water adds to 100.
- 2. the preparation method of the described composite lysozyme disinfecting liquid of claim 1 is characterized in that having following step:1) by proportioning described component lysozyme is purified, rationally is mixed and carries out emulsion reaction again;2) by proportioning described polyhexamethylene guanide is joined in the above-mentioned emulsion, stir, packing after sterilization is chilled to 30-40 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101157202A CN101461379A (en) | 2007-12-18 | 2007-12-18 | Composite lysozyme disinfecting liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101157202A CN101461379A (en) | 2007-12-18 | 2007-12-18 | Composite lysozyme disinfecting liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101461379A true CN101461379A (en) | 2009-06-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101157202A Pending CN101461379A (en) | 2007-12-18 | 2007-12-18 | Composite lysozyme disinfecting liquid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101461379A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138567A (en) * | 2011-02-22 | 2011-08-03 | 刘俊阁 | Composite preparation for killing bacteria and removing algae under water environment |
| CN105755183A (en) * | 2016-03-25 | 2016-07-13 | 深圳市大地康恩生物科技有限公司 | Leather-soaking bio-enzyme bactericide |
| CN106029089A (en) * | 2014-02-21 | 2016-10-12 | 丘比株式会社 | Norovirus inactivator and method for producing same, method for inactivating norovirus, method for producing lysozyme component for norovirus inactivation use, prophylactic or therapeutic agent for norovirus infection, and external preparation for skin for norovirus inactivation purposes |
| CN108324933A (en) * | 2018-04-08 | 2018-07-27 | 山东鲁北药业有限公司 | Lysozyme disinfecting liquid and its preparation method and application |
| CN109395068A (en) * | 2018-11-26 | 2019-03-01 | 浙江舒是生物科技有限公司 | A kind of refractory wound Special sterilizing liquid |
| CN109497093A (en) * | 2018-11-26 | 2019-03-22 | 浙江舒是生物科技有限公司 | A kind of thimerosal |
| CN110511836A (en) * | 2019-08-26 | 2019-11-29 | 阎昭良 | A kind of cleaning milk dirt, cleaning and sterilizing piece of spot and preparation method thereof |
| CN111248226A (en) * | 2020-03-13 | 2020-06-09 | 硅羿科技（上海）有限公司 | Novel broad-spectrum disinfectant and preparation method thereof |
| CN111298108A (en) * | 2020-04-10 | 2020-06-19 | 亘元(天津)生物医药科技有限公司 | Long-acting compound enzyme disinfection composition for children and application thereof |
| CN112261873A (en) * | 2018-04-19 | 2021-01-22 | 优卡健康有限公司 | Surfaces, air, fabric, paint, plastic, silicone and wood, polyethylene; antimicrobial properties of metals and derivatives |
| CN113395961A (en) * | 2018-11-30 | 2021-09-14 | 优卡健康有限公司 | Woven, nonwoven, cotton, blended nonwoven-cotton, polyethylene and polypropylene and polystyrene masks with antimicrobial properties, wound dressings, underpants, brassieres, handkerchiefs, pads, scrubbing pads, disposable surgical gowns, disposable sheets |
| CN115399339A (en) * | 2022-09-19 | 2022-11-29 | 深圳市减化生物科技有限公司 | Biological bactericide, preparation method thereof and biological bactericide product |
-
2007
- 2007-12-18 CN CNA2007101157202A patent/CN101461379A/en active Pending
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138567A (en) * | 2011-02-22 | 2011-08-03 | 刘俊阁 | Composite preparation for killing bacteria and removing algae under water environment |
| CN106029089B (en) * | 2014-02-21 | 2020-12-29 | 丘比株式会社 | Norovirus inactivator and method for producing same |
| CN106029089A (en) * | 2014-02-21 | 2016-10-12 | 丘比株式会社 | Norovirus inactivator and method for producing same, method for inactivating norovirus, method for producing lysozyme component for norovirus inactivation use, prophylactic or therapeutic agent for norovirus infection, and external preparation for skin for norovirus inactivation purposes |
| US11160849B2 (en) | 2014-02-21 | 2021-11-02 | National University Corporation Tokyo University Of Marine Science And Technology | Norovirus deactivator and method for producing same, method for deactivating norovirus, method for producing lysozyme component for norovirus deactivation use, prophylactic or therapeutic agent for norovirus infection, and external preparation for skin for norovirus deactivation purposes |
| CN105755183A (en) * | 2016-03-25 | 2016-07-13 | 深圳市大地康恩生物科技有限公司 | Leather-soaking bio-enzyme bactericide |
| CN105755183B (en) * | 2016-03-25 | 2018-10-12 | 深圳市大地康恩生物科技有限公司 | Leather soaking biological enzyme fungicide |
| CN108324933A (en) * | 2018-04-08 | 2018-07-27 | 山东鲁北药业有限公司 | Lysozyme disinfecting liquid and its preparation method and application |
| CN112261873A (en) * | 2018-04-19 | 2021-01-22 | 优卡健康有限公司 | Surfaces, air, fabric, paint, plastic, silicone and wood, polyethylene; antimicrobial properties of metals and derivatives |
| CN109497093A (en) * | 2018-11-26 | 2019-03-22 | 浙江舒是生物科技有限公司 | A kind of thimerosal |
| CN109395068A (en) * | 2018-11-26 | 2019-03-01 | 浙江舒是生物科技有限公司 | A kind of refractory wound Special sterilizing liquid |
| CN113395961A (en) * | 2018-11-30 | 2021-09-14 | 优卡健康有限公司 | Woven, nonwoven, cotton, blended nonwoven-cotton, polyethylene and polypropylene and polystyrene masks with antimicrobial properties, wound dressings, underpants, brassieres, handkerchiefs, pads, scrubbing pads, disposable surgical gowns, disposable sheets |
| CN110511836A (en) * | 2019-08-26 | 2019-11-29 | 阎昭良 | A kind of cleaning milk dirt, cleaning and sterilizing piece of spot and preparation method thereof |
| CN111248226A (en) * | 2020-03-13 | 2020-06-09 | 硅羿科技（上海）有限公司 | Novel broad-spectrum disinfectant and preparation method thereof |
| CN111298108A (en) * | 2020-04-10 | 2020-06-19 | 亘元(天津)生物医药科技有限公司 | Long-acting compound enzyme disinfection composition for children and application thereof |
| CN115399339A (en) * | 2022-09-19 | 2022-11-29 | 深圳市减化生物科技有限公司 | Biological bactericide, preparation method thereof and biological bactericide product |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090624 |