CN101590064A - Aseptic skin sterilizing agent for external use - Google Patents
Aseptic skin sterilizing agent for external use Download PDFInfo
- Publication number
- CN101590064A CN101590064A CNA2008101001472A CN200810100147A CN101590064A CN 101590064 A CN101590064 A CN 101590064A CN A2008101001472 A CNA2008101001472 A CN A2008101001472A CN 200810100147 A CN200810100147 A CN 200810100147A CN 101590064 A CN101590064 A CN 101590064A
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- CN
- China
- Prior art keywords
- sterilization
- external use
- sterilizing agent
- ethanol
- mentholum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The present invention relates to prescription of a kind of broad-spectrum sterilization, sterilization and aseptic skin sterilizing agent for external use and preparation method thereof.Can be widely used in sterilization, sterilization and the infection of various skin body surfaces.The present invention has the following advantages: sterilization, sterilization and the infection that 1) can be widely used in various skin body surfaces.2) antibiotic and sterilizing is effective, and is harmless to the article of being sterilized.3) safety non-toxic, environmentally safe.4) good product performance, price are low, easy to use, but wide popularization and application.
Description
Technical field
The present invention relates to a kind of broad-spectrum sterilization, sterilization and aseptic skin sterilizing agent for external use, form by polyhexamethylene guanidine, salicylic acid, Mentholum, miconazole nitrate, benzalkonium bromide, ethanol.This product raw material is easy to get, and is simple for production, all effective to most of microbe, and this product all reaches 99.99% to the sterilizing rate of escherichia coli, staphylococcus aureus and Candida albicans.Anaerobe is also had great antibacterial action, and said preparation is to the skin nonirritant, and toxicity is low, can be widely used in sterilization, sterilization and the infection of various skin body surfaces.Existing antibiotic and sterilizing product variety is a lot, and the antibiotic and sterilizing performance differs, and the branch of high, medium and low effect is arranged.The effective ingredient of high effect disinfectants and content are directly proportional with price often; And toxic, corrosivity, penetrating odor have pollution to environment, to being sterilized article certain damage are arranged.Therefore, every profession and trade is wished that always a kind of antibiotic and sterilizing efficient height can be arranged, safety and stability, environmentally safe, article is not had the prevention hand-foot-mouth disease disinfectant solution of damage.
Background technology
The object of the present invention is to provide a kind ofly can overcome the insufficient aseptic skin sterilizing agent for external use of existing procucts, have antimicrobial efficiency height, good stability, characteristics such as human body nonhazardous, environmentally safe, security performance height.
Summary of the invention
Main points of the present invention are to select suitable component, and rationally are mixed, through heat, dissolve, technology such as mixing, cooling forms compound disinfectant.
The prescription following (component and percentage by weight % thereof) that the present invention selects: salicylic acid 2.5-3.0; Mentholum 3.0-3.5; Miconazole nitrate 0.6-0.8; Benzalkonium bromide 0.3-0.5; Polyhexamethylene guanidine 0.3-0.5; Ethanol 30.0-40.0; Purified water adds to 100.
Salicylic acid, benzalkonium bromide are during polyhexamethylene guanidine, ethanol are, low effect disinfectants, as every kind of single sterilization component of compound recipe.Miconazole nitrate mainly kills anaerobe, in this component any folk prescription the time all can not the killing bacteria spore, be mixed in proportion into compound recipe after, but can the killing bacteria spore by its synergistic characteristic, improved sterilization effect greatly.Contain multiple composition in the compound disinfectant, the content ratio of each single component reduces relatively, and is therefore also few to side effect such as people's toxicity and zests.
The preparation method of product of the present invention is:
1). with the 45 ℃ of dissolvings of heating in proportion of salicylic acid, benzalkonium bromide, polyhexamethylene guanidine, miconazole nitrate, Mentholum;
2). ethanol is dissolved in the water to add in the above-mentioned solution in proportion cools off again;
3). carried out mixing 5 minutes with 80 rev/mins, carry out packing after the cooling, check, warehousing after passing.
The present invention has the following advantages: sterilization, sterilization and the infection that 1) can be widely used in various skin body surfaces.2). antibiotic and sterilizing is effective, and is harmless to the article of being sterilized.3). safety non-toxic, environmentally safe.4). good product performance, price are low, easy to use, but wide popularization and application.
The specific embodiment
The present invention is described in further detail below in conjunction with embodiment:
Be configured according to following table institute column data (percentage by weight %) and described step thereof:
Prescription one:
Salicylic acid 2.5-3.0
Mentholum 3.0-3.5
Miconazole nitrate 0.6-0.8
Benzalkonium bromide 0.3-0.5
Polyhexamethylene guanidine 0.3-0.5
Ethanol 30.0-40.0
Purified water adds to 100.
Prescription two:
Salicylic acid 2.6-3.0
Mentholum 3.2-3.5
Miconazole nitrate 0.7-0.8
Benzalkonium bromide 0.4-0.5
Polyhexamethylene guanidine 0.4-0.5
Ethanol 30.2-40.0
Purified water adds to 100.
Prescription three:
Salicylic acid 2.5-2.8
Mentholum 3.0-3.2
Miconazole nitrate 0.6-0.7
Benzalkonium bromide 0.3-0.4
Polyhexamethylene guanidine 0.3-0.5
Ethanol 30.0-38.0
Purified water adds to 100.
Prescription four:
Salicylic acid 2.6-2.8
Mentholum 3.1-3.3
Miconazole nitrate 0.6-0.7
Benzalkonium bromide 0.4-0.5
Polyhexamethylene guanidine 0.3-0.4
Ethanol 33.0-37.0
Purified water adds to 100.
Claims (2)
1, the present invention relates to a kind of aseptic skin sterilizing agent for external use, it is characterized in that having following prescription (gram, every liter of distilled water of ml/): salicylic acid 2.5-3.0; Mentholum 3.0-3.5; Miconazole nitrate 0.6-0.8; Benzalkonium bromide 0.3-0.5; Polyhexamethylene guanidine 0.3-0.5; Ethanol 30.0-40.0; Purified water adds to 100.
2, the preparation method of the described aseptic skin sterilizing agent for external use of a kind of claim 1 is characterized in that having following step:
1). with the 45 ℃ of dissolvings of heating in proportion of salicylic acid, benzalkonium bromide, polyhexamethylene guanidine, miconazole nitrate, Mentholum;
2). ethanol is dissolved in the water to add in the above-mentioned solution in proportion cools off again;
3). carried out mixing 5 minutes with 80 rev/mins, carry out packing after the cooling, check, warehousing after passing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101001472A CN101590064A (en) | 2008-05-26 | 2008-05-26 | Aseptic skin sterilizing agent for external use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101001472A CN101590064A (en) | 2008-05-26 | 2008-05-26 | Aseptic skin sterilizing agent for external use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101590064A true CN101590064A (en) | 2009-12-02 |
Family
ID=41405064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101001472A Pending CN101590064A (en) | 2008-05-26 | 2008-05-26 | Aseptic skin sterilizing agent for external use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101590064A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306327A (en) * | 2014-11-02 | 2015-01-28 | 卫国刚 | Polyhexamethylene guanidine lotion |
| JP2018016620A (en) * | 2016-07-13 | 2018-02-01 | 大日本除蟲菊株式会社 | Aqueous bactericidal composition |
| WO2024015595A1 (en) * | 2022-07-14 | 2024-01-18 | Vetnique Labs, Llc | Compositions for treatment of ear conditions |
-
2008
- 2008-05-26 CN CNA2008101001472A patent/CN101590064A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306327A (en) * | 2014-11-02 | 2015-01-28 | 卫国刚 | Polyhexamethylene guanidine lotion |
| JP2018016620A (en) * | 2016-07-13 | 2018-02-01 | 大日本除蟲菊株式会社 | Aqueous bactericidal composition |
| WO2024015595A1 (en) * | 2022-07-14 | 2024-01-18 | Vetnique Labs, Llc | Compositions for treatment of ear conditions |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Liu Xia Document name: Notification of before Expiration of Request of Examination as to Substance |
|
| DD01 | Delivery of document by public notice |
Addressee: Liu Xia Document name: Notification that Application Deemed to be Withdrawn |
|
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091202 |