CN101450068A - Premixing agent for preventing and treating livestock nematodiasis - Google Patents
Premixing agent for preventing and treating livestock nematodiasis Download PDFInfo
- Publication number
- CN101450068A CN101450068A CNA2007101505639A CN200710150563A CN101450068A CN 101450068 A CN101450068 A CN 101450068A CN A2007101505639 A CNA2007101505639 A CN A2007101505639A CN 200710150563 A CN200710150563 A CN 200710150563A CN 101450068 A CN101450068 A CN 101450068A
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- nematodiasis
- ivermectin
- albendazole
- adjuvant
- livestock
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Abstract
The invention relates to a premixing agent for treating livestock nematodiasis, comprising ivermectin, albendazol and auxiliary materials. The premixing agent is mainly used for preventing and treating livestock digestive canal nematodiasis and so on parasitic insect disease, has good preventing and treating actions for livestock digestive canal nematodiasis and ectozoa. The invention can treat the nematodiasis, meanwhile can prevent and treat the infection of the livestock parasite in vitro, can effectively improve the parasite-expelling effect, and has high safety.
Description
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of pre-mixing agent that is used to prevent and treat livestock nematodiasis.
Background technology
The gastrointestinal tract nematicide is the main parasitic parasitosis of harm animal health, and ill domestic animal is become thin, fertility performance descends, efficiency of feed utilization reduces, premunition is poor, causes the tremendous economic loss to herding animal husbandry.It is reported that 90% disease is caused by parasitic disease in the Australian sheep husbandry, annual economic loss and expenses for prevention and control are then up to more than 300,000,000 dollars.Xinjiang herd sheep and cattle parasitic infection rate almost 100%, wherein 30% infects seriously, and mortality rate reaches 2%, annual about 1.2 hundred million yuans of economic loss.
For a long time, people have obtained effect preferably with chemicals control domestic animal gastrointestinal tract nematicide, and many natural or synthetic chemicalses constantly are found and develop the control that is used for the animal parasite disease.At present, domestic and international control to domestic animal gastrointestinal tract nematicide still mainly is with the regular anthelmintic of various anthelmintic drugs.But over past ten years, people day by day recognize the negative effect with the medical treatment parasitic disease.The equal widespread reports in countries in the world the Drug resistance of gastrointestinal tract nematicide to anthelmintic commonly used such as Albendazole, levamisole etc.; The flock of sheep that Australia, New Zealand have the Drug resistance of Albendazole is finished up to more than 90%.Abuse the chemical medicine anthelmintic for a long time, repeatedly, also cause medicine residual and accumulate in carcass, make the livestock products downgrade; And after animal took medicine, the polypide of discharge and infectious worm's ovum caused the pollution of environment and the animal subinfection again to the gastrointestinal tract nematicide again, thereby have further increased the dependency of animal to pest-resistant medicine, have reduced prevention effect, and difficulty of prevention and cure is further strengthened.
Summary of the invention
Based on above-mentioned situation, the object of the present invention is to provide a kind of novel pre-mixing agent prescription, be used to prevent and treat the pre-mixing agent of livestock nematodiasis.
The object of the present invention is achieved like this: represent to be respectively ivermectin 0.3%-0.9% with percentage by weight, albendazole 1%-3%, adjuvant 98.7%-96.1%.
Described adjuvant comprises: anhydrous glucose, oral glucose, maize cob meal etc. are preferably anhydrous glucose.
In order to obtain better effect, preferred ingredient is: ivermectin 0.6%, albendazole 2%, adjuvant 97.4%.
Tablet of the present invention can adopt the general process of industry, equipment preparation.The following method preparation of preferred employing comprises step:
Earlier albendazole, ivermectin are pulverized with used adjuvant, pulverized back mistake 60 mesh sieves; The adjuvant of getting albendazole, ivermectin and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly.
In order to verify therapeutic effect of the present invention, get medicine of the present invention and do the clinical efficacy test on pig farm, Jinghai county.Get 20 of the piglets of new birth, add pre-mixing agent of the present invention in feedstuff, logotype 7 days was a course of treatment.Through above-mentioned prevention anthelmintic, nematicide does not take place in the piglet of test in its whole growth process.By clinical trial as can be seen, medicine of the present invention curative effect aspect the treatment livestock nematodiasis is certain, is suitable for applying in herding is produced.
Beneficial effect: the present invention fills a prescription and adopts ivermectin and two kinds of compatibility of drugss of albendazole to use, and can also prevent and treat the verminal infection of domestic animal in the treatment nematicide, effectively raises and drives away parasitic effect, has higher safety simultaneously.While medicine of the present invention has overcome life-time service and has been easy to generate chemical sproof shortcoming with a kind of deworm, uses prescription of the present invention to carry out anthelmintic, has significant curative effect.
The specific embodiment
Embodiment 1: earlier albendazole 10g, ivermectin 3g and used adjuvant 987g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting albendazole, ivermectin and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain albendazole 10g, ivermectin 3g.
Be mainly used in parasitic insect diseases such as control domestic animal gastrointestinal nematode disease, domestic animal gastrointestinal nematode, ectozoa are had good preventing and therapeutical effect.Usage and dosage: mixed feeding: add pre-mixing agent 100g of the present invention in every 500kg feedstuff, logotype 7 days was a course of treatment.Indivedual dogs, horse are higher to this product sensitivity, Ying Shenyong; The pregnant domestic animal forbidding.
Embodiment 2: earlier albendazole 20g, ivermectin 6g and used adjuvant 974g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting albendazole, ivermectin and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain albendazole 20g, ivermectin 6g.
Be mainly used in parasitic insect diseases such as control domestic animal gastrointestinal nematode disease, domestic animal gastrointestinal nematode, ectozoa are had good preventing and therapeutical effect.Usage and dosage: mixed feeding: add pre-mixing agent 150g of the present invention in every 500kg feedstuff, logotype 7 days was a course of treatment.Indivedual dogs, horse are higher to this product sensitivity, Ying Shenyong; The pregnant domestic animal forbidding.
Embodiment 3: earlier albendazole 30g, ivermectin 9g and used adjuvant 961g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting albendazole, ivermectin and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of pre-mixing agent, wherein contain albendazole 30g, ivermectin 9g.
Be mainly used in parasitic insect diseases such as control domestic animal gastrointestinal nematode disease, domestic animal gastrointestinal nematode, ectozoa are had good preventing and therapeutical effect.Usage and dosage: mixed feeding: add pre-mixing agent 50g of the present invention in every 500kg feedstuff, logotype 7 days was a course of treatment.Indivedual dogs, horse are higher to this product sensitivity, Ying Shenyong; The pregnant domestic animal forbidding.
Claims (3)
1, a kind of pre-mixing agent that is used for the treatment of livestock nematodiasis is characterized in that the medicine that this pre-mixing agent comprises is: ivermectin, albendazole and adjuvant.
2, a kind of pre-mixing agent that is used for the treatment of livestock nematodiasis according to claim 1, it is characterized in that: represent to be respectively ivermectin 0.3%-0.9% with percentage by weight, albendazole 1%-3%, adjuvant 98.7%-96.1%, described adjuvant comprises: anhydrous glucose, oral glucose, maize cob meal etc. are preferably anhydrous glucose.
3, a kind of pre-mixing agent that is used for the treatment of livestock nematodiasis according to claim 1, it is characterized in that: preferred ingredient is: ivermectin 0.6%, albendazole 2%, adjuvant 97.4%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505639A CN101450068A (en) | 2007-11-29 | 2007-11-29 | Premixing agent for preventing and treating livestock nematodiasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505639A CN101450068A (en) | 2007-11-29 | 2007-11-29 | Premixing agent for preventing and treating livestock nematodiasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101450068A true CN101450068A (en) | 2009-06-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101505639A Pending CN101450068A (en) | 2007-11-29 | 2007-11-29 | Premixing agent for preventing and treating livestock nematodiasis |
Country Status (1)
| Country | Link |
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| CN (1) | CN101450068A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966197A (en) * | 2010-07-26 | 2011-02-09 | 天津生机集团股份有限公司 | Composition for treating bovine severe compound parasitic infection and preparation method thereof |
| CN102935084A (en) * | 2012-11-13 | 2013-02-20 | 河南亚卫动物药业有限公司 | Compound ivermectin sustained release tablet and preparation method thereof |
| CN103083348A (en) * | 2012-05-10 | 2013-05-08 | 重庆金邦动物药业有限公司 | Albendazole/ivermectin powder for livestock |
| CN103599118A (en) * | 2012-05-10 | 2014-02-26 | 四川德润通生物科技有限公司 | Veterinary albendazole/ivermectin dry suspension |
| CN105409986A (en) * | 2015-11-19 | 2016-03-23 | 安徽农业大学 | Nematicidal compound containing fluopyram and albendazole and application thereof |
| CN105412132A (en) * | 2014-09-12 | 2016-03-23 | 中牧实业股份有限公司黄冈动物药品厂 | Compound invermectin slow-release granules and preparation method thereof |
| CN106389456A (en) * | 2016-11-16 | 2017-02-15 | 佛山市正典生物技术有限公司 | Veterinary albendazole ivermectin premixing agent and preparation method thereof |
| CN107349212A (en) * | 2017-06-27 | 2017-11-17 | 广东温氏大华农生物科技有限公司 | A kind of albendazole ivermectin pre-mixing agent and preparation method thereof |
| CN107550922A (en) * | 2017-03-20 | 2018-01-09 | 安徽天安生物科技股份有限公司 | A kind of prescription for treating pig acarid disease |
| CN109043159A (en) * | 2018-08-24 | 2018-12-21 | 广东群林牧业有限公司 | A kind of internal expelling parasite ewe feed formulation method |
-
2007
- 2007-11-29 CN CNA2007101505639A patent/CN101450068A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966197A (en) * | 2010-07-26 | 2011-02-09 | 天津生机集团股份有限公司 | Composition for treating bovine severe compound parasitic infection and preparation method thereof |
| CN103083348A (en) * | 2012-05-10 | 2013-05-08 | 重庆金邦动物药业有限公司 | Albendazole/ivermectin powder for livestock |
| CN103599118A (en) * | 2012-05-10 | 2014-02-26 | 四川德润通生物科技有限公司 | Veterinary albendazole/ivermectin dry suspension |
| CN102935084A (en) * | 2012-11-13 | 2013-02-20 | 河南亚卫动物药业有限公司 | Compound ivermectin sustained release tablet and preparation method thereof |
| CN105412132A (en) * | 2014-09-12 | 2016-03-23 | 中牧实业股份有限公司黄冈动物药品厂 | Compound invermectin slow-release granules and preparation method thereof |
| CN105409986A (en) * | 2015-11-19 | 2016-03-23 | 安徽农业大学 | Nematicidal compound containing fluopyram and albendazole and application thereof |
| CN106389456A (en) * | 2016-11-16 | 2017-02-15 | 佛山市正典生物技术有限公司 | Veterinary albendazole ivermectin premixing agent and preparation method thereof |
| CN106389456B (en) * | 2016-11-16 | 2020-06-09 | 佛山市正典生物技术有限公司 | Albendazole ivermectin premix for livestock and preparation method thereof |
| CN107550922A (en) * | 2017-03-20 | 2018-01-09 | 安徽天安生物科技股份有限公司 | A kind of prescription for treating pig acarid disease |
| CN107349212A (en) * | 2017-06-27 | 2017-11-17 | 广东温氏大华农生物科技有限公司 | A kind of albendazole ivermectin pre-mixing agent and preparation method thereof |
| CN109043159A (en) * | 2018-08-24 | 2018-12-21 | 广东群林牧业有限公司 | A kind of internal expelling parasite ewe feed formulation method |
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| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090610 |