CN101448845B - 用于不对称加成反应尤其加氢的过渡金属催化剂中的手性配体 - Google Patents

用于不对称加成反应尤其加氢的过渡金属催化剂中的手性配体 Download PDF

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CN101448845B
CN101448845B CN200780018505.9A CN200780018505A CN101448845B CN 101448845 B CN101448845 B CN 101448845B CN 200780018505 A CN200780018505 A CN 200780018505A CN 101448845 B CN101448845 B CN 101448845B
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alkyl
group
phenyl
perhaps
methyl
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CN101448845A (zh
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A·普法尔茨
Y·里博道伊尔
冯向东
B·拉马林加姆
B·普金
F·斯平德勒
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Solvias AG
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5022—Aromatic phosphines (P-C aromatic linkage)
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    • B01J31/1845—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing phosphorus
    • B01J31/1875—Phosphinites (R2P(OR), their isomeric phosphine oxides (R3P=O) and RO-substitution derivatives thereof)
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2495—Ligands comprising a phosphine-P atom and one or more further complexing phosphorus atoms covered by groups B01J31/1845 - B01J31/1885, e.g. phosphine/phosphinate or phospholyl/phosphonate ligands
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    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
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    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
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    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
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    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
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    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
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    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/822—Rhodium
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CN200780018505.9A 2006-05-23 2007-05-23 用于不对称加成反应尤其加氢的过渡金属催化剂中的手性配体 Active CN101448845B (zh)

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CH8312006 2006-05-23
CH00831/806 2006-05-23
PCT/EP2007/055026 WO2007135179A1 (en) 2006-05-23 2007-05-23 Chiral ligands used in transition metal catalysts for asymmetric addition reactions especially hydrogenation

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CN101448845B true CN101448845B (zh) 2012-12-12

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US (1) US8008529B2 (https=)
EP (1) EP2027134B1 (https=)
JP (1) JP5209611B2 (https=)
CN (1) CN101448845B (https=)
CA (1) CA2653150C (https=)
ES (1) ES2493634T3 (https=)
IL (1) IL195342A (https=)
WO (1) WO2007135179A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006117369A1 (de) * 2005-05-03 2006-11-09 Solvias Ag Ferrocenylliganden, herstellung und verwendung
US8415488B2 (en) 2007-11-20 2013-04-09 Solvias Ag Bidentate secondary phosphine oxide chiral ligands for use in asymmetric addition reactions
EP2186817A1 (en) * 2008-11-14 2010-05-19 Solvias AG Chiral ligands
CN112824422B (zh) * 2019-11-21 2023-01-13 中国科学院大连化学物理研究所 一种手性二茂铁-吲哚双膦配体及其制备方法和其应用
CN112480179B (zh) * 2020-11-24 2025-11-14 苏州鹏旭医药科技有限公司 一种取代二茂铁基二膦均相催化剂配体

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004099226A1 (en) * 2003-05-09 2004-11-18 Umicore Ag & Co. Kg Substituted ferrocenyldiphosphines as ligands for homogeneous hydrogenation catalysts
WO2005056568A1 (de) * 2003-12-12 2005-06-23 Solvias Ag Ferrocenyl-1, 2-diphosphine, deren herstellung und deren verwendung
WO2005068477A1 (en) * 2004-01-14 2005-07-28 Phoenix Chemicals Limited Metallocene-based chiral phosphine or arsine ligands
WO2006003195A1 (en) * 2004-07-05 2006-01-12 Solvias Ag Tetradentate ferrocene ligands and their use

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
JP2002527413A (ja) * 1998-10-13 2002-08-27 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 触媒用の重合体に担持された燐配位子

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004099226A1 (en) * 2003-05-09 2004-11-18 Umicore Ag & Co. Kg Substituted ferrocenyldiphosphines as ligands for homogeneous hydrogenation catalysts
WO2005056568A1 (de) * 2003-12-12 2005-06-23 Solvias Ag Ferrocenyl-1, 2-diphosphine, deren herstellung und deren verwendung
WO2005068477A1 (en) * 2004-01-14 2005-07-28 Phoenix Chemicals Limited Metallocene-based chiral phosphine or arsine ligands
WO2006003195A1 (en) * 2004-07-05 2006-01-12 Solvias Ag Tetradentate ferrocene ligands and their use

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CA2653150C (en) 2014-05-13
ES2493634T3 (es) 2014-09-12
US20090171114A1 (en) 2009-07-02
WO2007135179A1 (en) 2007-11-29
IL195342A (en) 2015-08-31
EP2027134A1 (en) 2009-02-25
EP2027134B1 (en) 2014-07-16
CN101448845A (zh) 2009-06-03
CA2653150A1 (en) 2007-11-29
IL195342A0 (en) 2009-08-03
US8008529B2 (en) 2011-08-30
JP2009537607A (ja) 2009-10-29
JP5209611B2 (ja) 2013-06-12

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