CN101443080B - 肽在控制辐射损伤中的用途 - Google Patents

肽在控制辐射损伤中的用途 Download PDF

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Publication number
CN101443080B
CN101443080B CN200780016562.3A CN200780016562A CN101443080B CN 101443080 B CN101443080 B CN 101443080B CN 200780016562 A CN200780016562 A CN 200780016562A CN 101443080 B CN101443080 B CN 101443080B
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CN
China
Prior art keywords
radiation
peptide
peptides
dose
pharmaceutical composition
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Expired - Fee Related
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CN200780016562.3A
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English (en)
Chinese (zh)
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CN101443080A (zh
Inventor
R·贝内
N·A·卡恩
R·M·卡尔顿
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Biotempt BV
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Biotempt BV
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Priority claimed from EP06076181A external-priority patent/EP1864692A1/en
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Publication of CN101443080A publication Critical patent/CN101443080A/zh
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Publication of CN101443080B publication Critical patent/CN101443080B/zh
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN200780016562.3A 2006-03-07 2007-03-06 肽在控制辐射损伤中的用途 Expired - Fee Related CN101443080B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US77989606P 2006-03-07 2006-03-07
US60/779,896 2006-03-07
US81187806P 2006-06-07 2006-06-07
EP06076181A EP1864692A1 (en) 2006-06-07 2006-06-07 Use of peptides for the control of radiation injury
US60/811,878 2006-06-07
EP06076181.4 2006-06-07
PCT/NL2007/050092 WO2007102735A1 (en) 2006-03-07 2007-03-06 Use of peptides for the control of radiation injury

Publications (2)

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CN101443080A CN101443080A (zh) 2009-05-27
CN101443080B true CN101443080B (zh) 2015-01-14

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CN200780016562.3A Expired - Fee Related CN101443080B (zh) 2006-03-07 2007-03-06 肽在控制辐射损伤中的用途

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JP (1) JP5307559B2 (enExample)
CN (1) CN101443080B (enExample)
IL (1) IL193910A (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6378307B2 (ja) * 2013-03-11 2018-08-22 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 肺機能を改善するためならびに放射線誘発肺合併症の予防および／または処置のための物質および方法
CN108484738B (zh) * 2018-03-28 2022-03-15 中国人民解放军军事科学院军事医学研究院 辐抗肽突变蛋白及其制备与纯化方法
CN118546262B (zh) * 2024-06-20 2025-07-29 首都医科大学 Ala-Gln-Gly的四聚体及其制备和应用
CN121102437A (zh) * 2025-11-07 2025-12-12 复旦大学 一种多肽在制备治疗放射性肠损伤药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572688A1 (en) * 1992-05-30 1993-12-08 Predrag Dr.Sc. Sikiric Peptides with organo-protective activity, the process for preparing them and their use in therapy
CN1238217A (zh) * 1999-06-24 1999-12-15 中国医学科学院血液学研究所 一种用于辐射损伤治疗的多肽类药物组合物
WO2001051508A1 (en) * 2000-01-14 2001-07-19 Science & Technology Corporation @ Unm Peptide inhibitors of lfa-1/icam-1 interaction
CN1717587A (zh) * 2002-11-25 2006-01-04 希克龙制药公司 使用α胸腺素防护辐射损伤的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2860637B2 (ja) * 1995-12-11 1999-02-24 末綱 陽子 新規なペプチドおよび活性化酸素阻害剤
JP2835504B2 (ja) * 1995-12-11 1998-12-14 末綱 陽子 新規なペプチドおよび活性化酸素阻害剤
JP3368735B2 (ja) * 1995-12-26 2003-01-20 住友金属工業株式会社 高強度・低延性非調質鋼
US20050227925A1 (en) * 2004-04-08 2005-10-13 Robbert Benner Compositions capable of reducing elevated blood urea concentration

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572688A1 (en) * 1992-05-30 1993-12-08 Predrag Dr.Sc. Sikiric Peptides with organo-protective activity, the process for preparing them and their use in therapy
CN1238217A (zh) * 1999-06-24 1999-12-15 中国医学科学院血液学研究所 一种用于辐射损伤治疗的多肽类药物组合物
WO2001051508A1 (en) * 2000-01-14 2001-07-19 Science & Technology Corporation @ Unm Peptide inhibitors of lfa-1/icam-1 interaction
CN1717587A (zh) * 2002-11-25 2006-01-04 希克龙制药公司 使用α胸腺素防护辐射损伤的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
《History of chemical and biological warfare agents》;Szinicz et al;《Toxicology》;20051030;第214卷(第3期);167-181 *
《Rapid screening of urinary proline-hydroxyproline dipeptide in bone turnover studies》;Husek P et al;《Journal of Chromatography B: Biomedical Sciences & Applications》;20020205;第767卷(第1期);169-174 *

Also Published As

Publication number Publication date
JP5307559B2 (ja) 2013-10-02
IL193910A (en) 2015-09-24
IL193910A0 (en) 2011-08-01
HK1129861A1 (en) 2009-12-11
JP2009529037A (ja) 2009-08-13
CN101443080A (zh) 2009-05-27

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