CN101437807A - 被吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及其制备方法 - Google Patents

被吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及其制备方法 Download PDF

Info

Publication number
CN101437807A
CN101437807A CNA2007800159285A CN200780015928A CN101437807A CN 101437807 A CN101437807 A CN 101437807A CN A2007800159285 A CNA2007800159285 A CN A2007800159285A CN 200780015928 A CN200780015928 A CN 200780015928A CN 101437807 A CN101437807 A CN 101437807A
Authority
CN
China
Prior art keywords
alkyl
group
compound
methyl
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800159285A
Other languages
English (en)
Chinese (zh)
Inventor
马赛厄斯·埃克哈特
弗兰克·希梅尔斯巴赫
彼得·艾克尔曼
阿基姆·索尔
利奥·托马斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of CN101437807A publication Critical patent/CN101437807A/zh
Pending legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CNA2007800159285A 2006-05-03 2007-05-02 被吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及其制备方法 Pending CN101437807A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06113412.8 2006-05-03
EP06113412 2006-05-03
EP06124833.2 2006-11-27
EPPCT/EP2007/051411 2007-02-14

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201310616828.5A Division CN103601709A (zh) 2006-05-03 2007-05-02 吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及制备方法
CN201110219008.3A Division CN102351918B (zh) 2006-05-03 2007-05-02 被吡喃型葡萄糖基取代的苯甲腈衍生物及含所述化合物的药物组合物

Publications (1)

Publication Number Publication Date
CN101437807A true CN101437807A (zh) 2009-05-20

Family

ID=40711593

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800159285A Pending CN101437807A (zh) 2006-05-03 2007-05-02 被吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及其制备方法

Country Status (4)

Country Link
CN (1) CN101437807A (es)
ES (1) ES2369016T3 (es)
UA (1) UA94454C2 (es)
ZA (1) ZA200807712B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019185026A1 (zh) * 2018-03-30 2019-10-03 南京明德新药研发有限公司 作为SGLTs抑制剂的葡糖苷类衍生物及其应用
CN111511725A (zh) * 2017-12-19 2020-08-07 勃林格殷格翰维特梅迪卡有限公司 1-氰基-2-(4-环丙基-苄基)-4-(β-D-吡喃葡萄糖-1-基)-苯、L-脯氨酸和水的1:1:1共晶体的合成

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005092877A1 (de) * 2004-03-16 2005-10-06 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituierte benzol-derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005092877A1 (de) * 2004-03-16 2005-10-06 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituierte benzol-derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111511725A (zh) * 2017-12-19 2020-08-07 勃林格殷格翰维特梅迪卡有限公司 1-氰基-2-(4-环丙基-苄基)-4-(β-D-吡喃葡萄糖-1-基)-苯、L-脯氨酸和水的1:1:1共晶体的合成
CN111511725B (zh) * 2017-12-19 2024-04-09 勃林格殷格翰维特梅迪卡有限公司 1-氰基-2-(4-环丙基-苄基)-4-(β-D-吡喃葡萄糖-1-基)-苯、L-脯氨酸和水的1:1:1共晶体的合成
WO2019185026A1 (zh) * 2018-03-30 2019-10-03 南京明德新药研发有限公司 作为SGLTs抑制剂的葡糖苷类衍生物及其应用

Also Published As

Publication number Publication date
ES2369016T3 (es) 2011-11-24
ZA200807712B (en) 2010-10-27
UA94454C2 (en) 2011-05-10

Similar Documents

Publication Publication Date Title
CN102351918B (zh) 被吡喃型葡萄糖基取代的苯甲腈衍生物及含所述化合物的药物组合物
EP1989191B1 (en) Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
JP5384343B2 (ja) グルコピラノシル−置換シクロプロピルベンゼン誘導体、そのような化合物を含む医薬組成物、ｓｇｌｔ阻害剤としてのそれらの使用及びそれらの製造方法
CN103467423B (zh) 吡喃葡萄糖基取代的苯基衍生物、含该化合物的药物、其用途及其制造方法
CN101384576A (zh) 被吡喃型葡萄糖基取代的苯甲腈衍生物、含此化合物的药物组合物、其用途及其制备方法
CN101437807A (zh) 被吡喃型葡萄糖基取代的苯甲腈衍生物、含所述化合物的药物组合物、其用途及其制备方法
MX2008009165A (es) Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1130493

Country of ref document: HK

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1130493

Country of ref document: HK

C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20090520