UA94454C2 - Glucopyranosyl-substituted benzonitrile derivatives - Google Patents

Glucopyranosyl-substituted benzonitrile derivatives

Info

Publication number
UA94454C2
UA94454C2 UAA200813468A UAA200813468A UA94454C2 UA 94454 C2 UA94454 C2 UA 94454C2 UA A200813468 A UAA200813468 A UA A200813468A UA A200813468 A UAA200813468 A UA A200813468A UA 94454 C2 UA94454 C2 UA 94454C2
Authority
UA
Ukraine
Prior art keywords
hydroxy
ethyl
methyl
butyl
glucopyranosyl
Prior art date
Application number
UAA200813468A
Other languages
Russian (ru)
Inventor
Маттиас Экхардт
Франк Химмельсбах
Петер Айкельманн
Ахим Зауэр
Лео Томас
Original Assignee
Бьёрингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бьёрингер Ингельхайм Интернациональ Гмбх filed Critical Бьёрингер Ингельхайм Интернациональ Гмбх
Publication of UA94454C2 publication Critical patent/UA94454C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

, (I)Glucopyranosyl substituted, benzonitrile derivatives defined according to formula I, including the tautomers, the stereoisomers thereof, the mixtures thereof and the salts thereof. The compounds according to the invention are suitable for the treatment of metabolic disorders, formula (I), wherein Rdenotes hydrogen, fluorine, chlorine, bromine, iodine, methyl, ethyl, propyl, isopropyl, butyl, sec-butyl, iso-butyl, tert-butyl, 3-methyl-but-l-yl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, 1-hydroxy-cyclopropyl, 1-hydroxy-cyclobutyl, 1-hydroxy-cyclopentyl, 1-hydroxy-cyclohexyl, difluoromethyl, trifluoromethyl, pentafluoroethyl, 2-hydroxyl-ethyl, hydrox-ymethyl, 3-hydroxy-propyl, 2-hydroxy-2-methyl-prop-1-yl, 3-hydroxy-3-methyl-but-l-yl, 1-hydroxy-l-methyl-ethyl, 2,2,2-trifluoro-l-hydroxy-1-methyl-ethyl, 2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl, 2-methoxy-ethyl, 2-ethoxy-ethyl, hydroxy, difiuoromethyloxy, trifluoromethyloxy, 2-methyloxy-ethyloxy, methylsulfanyl, methylsulfinyl, methlysulfonyl, ethylsulfinyl, ethylsulfonyl, trimethylsilyl or cyano.
UAA200813468A 2006-05-03 2007-05-02 Glucopyranosyl-substituted benzonitrile derivatives UA94454C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06113412 2006-05-03

Publications (1)

Publication Number Publication Date
UA94454C2 true UA94454C2 (en) 2011-05-10

Family

ID=40711593

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200813468A UA94454C2 (en) 2006-05-03 2007-05-02 Glucopyranosyl-substituted benzonitrile derivatives

Country Status (4)

Country Link
CN (1) CN101437807A (en)
ES (1) ES2369016T3 (en)
UA (1) UA94454C2 (en)
ZA (1) ZA200807712B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021506962A (en) * 2017-12-19 2021-02-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ Synthesis of 1: 1: 1 co-crystal consisting of 1-cyano-2- (4-cyclopropyl-benzyl) -4- (β-D-glucopyranos-1-yl) -benzene, L-proline and water
WO2019185026A1 (en) * 2018-03-30 2019-10-03 南京明德新药研发有限公司 Glucoside derivatives acting as inhibitors of sglts, and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1730131T1 (en) * 2004-03-16 2012-08-31 Boehringer Ingelheim Int Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof

Also Published As

Publication number Publication date
CN101437807A (en) 2009-05-20
ZA200807712B (en) 2010-10-27
ES2369016T3 (en) 2011-11-24

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