CN101433632A - Antiradiation composition for improving immunity - Google Patents
Antiradiation composition for improving immunity Download PDFInfo
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- CN101433632A CN101433632A CNA2007101774940A CN200710177494A CN101433632A CN 101433632 A CN101433632 A CN 101433632A CN A2007101774940 A CNA2007101774940 A CN A2007101774940A CN 200710177494 A CN200710177494 A CN 200710177494A CN 101433632 A CN101433632 A CN 101433632A
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Abstract
The invention discloses a composition having the efficacies of improving immunity and resisting irradiation and a method fore preparing the same. The composition is prepared from raw materials such as integripetal rhodiola herb, astragalus root, green tea, spirulina and polyrhachis vicina. The composition has the efficacies of improving the immunity and resisting the irradiation.
Description
Technical field
The present invention relates to a kind of the have immunity of raising, radiation-resistant composition and method of making the same.
Background technology
Radiation can directly cause histiocyte amplifying nucleic acid, proteinic molecular structure to destroy and dysbolismus, particularly to the synthetic vigorous histoorgan of DNA, as: bone marrow, thymus, spleen, lymph node etc. cause the hematopoietic function obstacle.Be subjected to radiating people for a long time, can the chronic radiation disease take place because of the accumulation of radiation dose, its cardinal symptom is leukopenia, infertile, fatigue and weak and weakness etc.Ubiquity various rays and radioactive substance in human lives's the environment, also can not be ignored by the intravital radionuclide of the air admission of diet and absorption in addition.For reducing the harm that radiation caused, some radioprotectants arise at the historic moment.But traditional radioprotectant has certain toxic and side effects, and old friends more and more pay attention to the radiation resistance of Chinese herbal medicine and wholefood.
The Radix Astragali strengthens the activate the phagocytic capacity of mononuclear phagocyte in humoral immunization, and to somatic cell, natural killer cell discharges immunologic active material, inducement interferon, and many-sides such as interleukin show multiple physiologically active.One of its antiviral principle may be to improve the ability of patient's leukocyte inducement interferon, and IgE3 significantly increased after the normal person took Radix Astragali herb extractum sheet.The Radix Astragali can promote the phagocytic function of macrophage, can promote the propagation of B cell and suppress the total complement activity.
The Radix Astragali may be relevant with the generation of its adjusting IgG subclass to the regulating action of T cell and excretory cytokine thereof.
There is immunoregulation effect in Radix Astragali energy enhancing non-specific immunity function to body's immunity.
The Radix Astragali has the certain protection effect to the immune system injury due to the Co60 x radiation x.Body weight, leukocyte number and hepatocyte structure to experimental animal all have significant protective effect.Its mechanism of action may have non-oxidizability and remove the free radical effect with Radix Astragali total flavones, make immunocyte avoid the damage of lipid peroxidation relevant, Radix Astragali total flavones may also have the function that changes the immunocyte energy metabolism and promote lymphocytic cell division simultaneously.
Contain Quercetin in the Radix Rhodiolae; kaempferol; anthocyanin; rodalgin; alginin; rodalginin; rodalin and acylate, rhodalgisin; rhodalgiside; rhodalide; rhodioloside; rhodiocyanosideA; B; gossypetin-7-O-β-D-glucosyl group-a-L-rhamnoside; picein; skimmin; Isoquercitrin; the rutin glycoside; Arbutin; daucosterol; gossypitrin-8-glucose; glycoside in the handkerchief; heterodnedrin; lotaustralin; crenulatin; rhodioloside and Jujubogenin tyrosol; Rosavin-Rosin; rosari; rosavin; coumarin; tannin; volatile oil and fatty oils; aminoacid and polysaccharide compound.。Have radioprotective, anoxia enduring, resisting fatigue, cold-resistant, regulate effect such as human immunity.
Radix Rhodiolae all has potentiation to mouse cell and humoral immune function.Radix Rhodiolae can obviously improve quantity and the periphery blood T lymphocyte percentage rate and the special antibody secreting cell number of mice of spleen antibody-producting cell; The mixed lymphocyte reaction of delayed hypersensitivity intensity, special-shaped mice and the phagocytic function of macrophage all there is potentiation;
Radix Rhodiolae can resist the influence to body of x-ray radiation, microwave radiation, reduces that the splenocyte that causes because of x-ray radiation destroys and the generation of peripheral blood deformity erythrocyte, heart and liver lipid peroxide.Radix Rhodiolae improves the survival rate of Co60 roentgenization mice and to bone marrow hematogenesis the significant protection function can be arranged, and obviously raising is subjected to according to mice spleen T crust cell rate of rotation.
Tea polyphenols has radioprotective and improves immunity function.Laboratory observation can obviously improve and is subjected to irradiation mouse femur bone marrow nucleated cell number and dna content can significantly suppress its bone marrow of sternum polychromatic erythrocyte micronucleus number simultaneously to drinking certain density green tea immersion in advance, this may reduce the damage of DNA by the expression of inhibited oxidation effect and cytochrome P450 gene by two kinds of important tea polyphenols (theaflavin and abrownin), thereby alleviates the damage of irradiation to hereditary material.
Its nutritional labeling of spirulina mainly contains: protein (60-70%), the whole essential amino acids of human body, 13 1 carotene, unsaturated fatty acid, especially contain Y linolenic acid, multivitamin, trace element, contain abundant ferrum, also have polysaccharide, chlorophyll and distinctive phycocyanin.Experimental results show that spirulina polysaccharide and phycocyanin mice is subjected to the Co60 roentgenization after survival rate more much higher than matched group, and have hematopoietic stem cell to form, bone marrow nucleus quantity also increases.The main health care and the medical value of spirulina.The human spirulina mice of feeding is arranged, find that it all has enhancing to the immunoreation of thymus dependent, thymus independent antigen.Carotene, polysaccharide all have the function of direct adjusting and activate immunity reaction.
The Polyhachis vicina Roger body contains multiple compositions such as protein, aminoacid, and contained protein is up to 58.83%, considerably beyond foods such as the most normal human edible grain, oil, meat, egg, fowl, fishes.Polyhachis vicina Roger has dual regulation to immunologic function.Its water extract is a kind of immunostimulant, can promote organ hypertrophy, growths such as aged Mus thymus, spleen, blood leucocyte and lysozyme are increased improve the macrophage phagocytic ability, improve quantity and serum antibody level that antigen triggers back specific antibody cellulation.EaRFC, EtRFC and ANA positive cell and lymphocyte absolute value are raise, promote the formation and the lymphocytic conversion of immunoglobulin, significantly improve low immunologic function.On the other hand, assist the balance of T cell and suppressor T cell again by immunomodulating, play immunosuppressant.
Summary of the invention
The object of the invention is to provide a kind of the have immunity of raising, radiation-resistant compositions.
Another purpose of the present invention is to provide a kind of the have immunity of raising, radiation-resistant preparation of compositions method.
The present invention is implemented by the following technical programs.
Said composition can be made by the raw material of following weight portion:
Radix Rhodiolae 2-20 spirulina 2-15 green tea 10-60 Radix Astragali 3-20 Polyhachis vicina Roger 3-20
The raw material of above-mentioned weight portion can be preferably: Radix Rhodiolae 4 spirulinas 12 green tea 30 Radixs Astragali 8 Polyhachis vicina Roger 5
Radix Rhodiolae, the Radix Astragali, green tea all have radioprotective, improve the immunity effect.Spirulina is rich in nutritional labeling, also has radioprotective, improves the immunity effect.Polyhachis vicina Roger is rich in nutritional labeling, and immunologic function is had dual regulation.The present composition uses with above-mentioned material combination, can Synergistic.
Present composition functional trial result shows to have radioprotective, improve immunity.Cobalt 60 rays detect the recovery of its survival rate, myeloid element propagation and immunologic function with after penetrating mice.The result shows that the present composition has tangible radiate protective action.Select amynologic index such as lymphatic organ organ coefficient, delayed allergy, spleen antibody-producting cell number, macrophage phagocytic index to observe the present composition to the BALB/c mouse Immune Effects.The result shows, can increase the relative mass of BALB/c mouse thymus, the quantity that foot is opened up thickness and spleen antibody-producting cell in the 500-2000mg/kg dosage range.
The specific embodiment
The present invention is described further by embodiment.
Embodiment 1
The present composition can be made by the raw material of following weight portion:
Radix Rhodiolae 2 spirulinas 2 green tea 10 Radixs Astragali 3 Polyhachis vicina Roger 20
Embodiment 2
The present composition can be made by the raw material of following weight portion:
Radix Rhodiolae 20 spirulinas 15 green tea 60 Radixs Astragali 20 Polyhachis vicina Roger 3
Embodiment 3
The present composition can be made by the raw material of following weight portion:
Radix Rhodiolae 10 spirulinas 9 green tea 30 Radixs Astragali 12 Polyhachis vicina Roger 15
Embodiment 4
The present composition can be made by the raw material of following weight portion:
Radix Rhodiolae 16 spirulinas 9 green tea 23 Radixs Astragali 8 Polyhachis vicina Roger 9
Claims (2)
1, a kind of compositions that has radioprotective, improves the immunity effect is characterized in that said composition made by the raw material of following weight portion: Radix Rhodiolae 2-20, spirulina 2-15, green tea 10-60, Radix Astragali 3-20, Polyhachis vicina Roger 3-20.
2, compositions according to claim 1 is characterized in that said composition made by the raw material of following weight portion: Radix Rhodiolae 4, spirulina 12, green tea 30, the Radix Astragali 8, Polyhachis vicina Roger 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774940A CN101433632A (en) | 2007-11-16 | 2007-11-16 | Antiradiation composition for improving immunity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101774940A CN101433632A (en) | 2007-11-16 | 2007-11-16 | Antiradiation composition for improving immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101433632A true CN101433632A (en) | 2009-05-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CNA2007101774940A Pending CN101433632A (en) | 2007-11-16 | 2007-11-16 | Antiradiation composition for improving immunity |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173391A (en) * | 2013-05-27 | 2014-12-03 | 广州加原医药科技有限公司 | Application of root or stem of iodes vitiginea in preparation of health product having anti-radiation effect |
| CN105724988A (en) * | 2016-02-22 | 2016-07-06 | 叶芳 | Composite fruit and vegetable beverage capable of reducing computer radiation hazard |
| CN109865132A (en) * | 2019-04-01 | 2019-06-11 | 海南林恒制药股份有限公司 | A kind of preparation of spirulina tablet and its preparation method and application adjusting immunity |
-
2007
- 2007-11-16 CN CNA2007101774940A patent/CN101433632A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173391A (en) * | 2013-05-27 | 2014-12-03 | 广州加原医药科技有限公司 | Application of root or stem of iodes vitiginea in preparation of health product having anti-radiation effect |
| CN105724988A (en) * | 2016-02-22 | 2016-07-06 | 叶芳 | Composite fruit and vegetable beverage capable of reducing computer radiation hazard |
| CN109865132A (en) * | 2019-04-01 | 2019-06-11 | 海南林恒制药股份有限公司 | A kind of preparation of spirulina tablet and its preparation method and application adjusting immunity |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090520 |