CN101426520A - 通过给予组织因子途径抑制剂(tfpi)治疗社区获得性重症肺炎 - Google Patents

通过给予组织因子途径抑制剂(tfpi)治疗社区获得性重症肺炎 Download PDF

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Publication number
CN101426520A
CN101426520A CNA2005800144064A CN200580014406A CN101426520A CN 101426520 A CN101426520 A CN 101426520A CN A2005800144064 A CNA2005800144064 A CN A2005800144064A CN 200580014406 A CN200580014406 A CN 200580014406A CN 101426520 A CN101426520 A CN 101426520A
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CN
China
Prior art keywords
tfpi
ala
analog
close rate
nonglycosylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800144064A
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English (en)
Chinese (zh)
Inventor
A·克里西
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Novartis Vaccines and Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Publication of CN101426520A publication Critical patent/CN101426520A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNA2005800144064A 2004-03-17 2005-03-17 通过给予组织因子途径抑制剂(tfpi)治疗社区获得性重症肺炎 Pending CN101426520A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55468104P 2004-03-17 2004-03-17
US60/554,681 2004-03-17

Publications (1)

Publication Number Publication Date
CN101426520A true CN101426520A (zh) 2009-05-06

Family

ID=35394617

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800144064A Pending CN101426520A (zh) 2004-03-17 2005-03-17 通过给予组织因子途径抑制剂(tfpi)治疗社区获得性重症肺炎

Country Status (16)

Country Link
US (1) US20080286279A1 (https=)
EP (1) EP1729791A2 (https=)
JP (1) JP2007532486A (https=)
KR (1) KR20070007336A (https=)
CN (1) CN101426520A (https=)
AU (1) AU2005244249A1 (https=)
BR (1) BRPI0508992A (https=)
CA (1) CA2560103A1 (https=)
IL (1) IL178115A0 (https=)
MX (1) MXPA06010587A (https=)
NO (1) NO20064674L (https=)
RU (1) RU2006136267A (https=)
SG (1) SG150552A1 (https=)
TN (1) TNSN06295A1 (https=)
WO (1) WO2005110059A2 (https=)
ZA (1) ZA200608413B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102639556A (zh) * 2009-09-22 2012-08-15 X免疫股份公司 多肽及其用途
CN112587522A (zh) * 2020-12-03 2021-04-02 中国海洋大学 替加色罗在制备用于预防或治疗冠状病毒感染的药物中的应用

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102639556A (zh) * 2009-09-22 2012-08-15 X免疫股份公司 多肽及其用途
CN112587522A (zh) * 2020-12-03 2021-04-02 中国海洋大学 替加色罗在制备用于预防或治疗冠状病毒感染的药物中的应用
CN112587522B (zh) * 2020-12-03 2022-11-25 中国海洋大学 替加色罗在制备用于预防或治疗冠状病毒感染的药物中的应用

Also Published As

Publication number Publication date
WO2005110059A3 (en) 2009-04-09
SG150552A1 (en) 2009-03-30
JP2007532486A (ja) 2007-11-15
IL178115A0 (en) 2008-03-20
WO2005110059A2 (en) 2005-11-24
CA2560103A1 (en) 2005-11-24
EP1729791A2 (en) 2006-12-13
BRPI0508992A (pt) 2007-09-04
MXPA06010587A (es) 2007-03-29
ZA200608413B (en) 2008-06-25
TNSN06295A1 (en) 2007-12-03
NO20064674L (no) 2006-11-29
AU2005244249A1 (en) 2005-11-24
RU2006136267A (ru) 2008-04-27
US20080286279A1 (en) 2008-11-20
KR20070007336A (ko) 2007-01-15

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Open date: 20090506