CN101411808B

CN101411808B - Method for preparing Chinese medicine for treating heat intestine and stomach type constipation

Info

Publication number: CN101411808B
Application number: CN2008101594482A
Authority: CN
Inventors: 戴桂兰; 潘新; 孙健
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-12-01
Filing date: 2008-12-01
Publication date: 2010-12-22
Anticipated expiration: 2028-12-01
Also published as: CN101411808A

Abstract

The invention relates to a method for preparing a traditional Chinese medicine for treating gastrointestinal broiling type constipation and belongs to the technical field of traditional Chinese medicine preparation method. At present, catharsis is often applied to the treatment of constipation to stimulate an intestinal wall receptor in order to increase the peristalsis of intestinal canals and the glandular secretion so as to accelerate excretion; however, the prior method has certain side effect and is taboo to pregnant women and infants. The method comprises the following technical proposal: rhubarb, senna, gardenia, fructus sophorae, radices sanguisorbae, cacumen platycladi, rumex japonicus root, fructus aurantii immaturus, magnolia officinalis, longstamen onion bulb, pericarpium arecae, walnut meat, angelica, figwort, semen sesami, semen cannabis, semen pruni, honey, almond, trichosanthes kirilowii, radices saussureae, semen raphani and liquorice are taken out, put to water of 1,350 millilitres, soaked for 30 minutes, decocted by mild fire; the decocted medical liquid is filtered through a gauze to remove residue; the decocted medical liquid is 500 millilitres, that is the traditional Chinese medicine for treating gastrointestinal broiling type constipation. The traditional Chinese medicine has the advantages of small side effect, good absorption in alimentary canal, stable curative effect and uneasy rebounding after the traditional Chinese medicine liquid is taken orally.

Description

A kind of Chinese medicinal preparation method for the treatment of heat intestine and stomach type constipation

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of heat intestine and stomach type constipation more specifically.

Background technology

Think at present: stool is often constipated obstructed, and defecation time prolongs, and excrement matter drying is hard or meaning is arranged just and the difficult defecation person is called constipation.Usually use catharsis in the treatment, stimulate the intestinal wall sensor, intestinal tube wriggling and glandular secretion are increased, or stop the enteral moisture absorption, feces is softened or quicken its drainage.1. using sulfated magnesium: nausea and vomiting can occur, take in a large number and can cause dehydration; 2. use phenolphthalein: can cause erythra, allergic colitis and bleeding tendency; 3. use Oleum Ricini: anemia of pregnant woman and baby avoid usefulness.Can cause nausea, high rushing down appears in a few peoples.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of heat intestine and stomach type constipation.Its pathogenic factor mainly is that the large intestine conduction function is not normal, and feces overstays at enteral, and moisture is absorbed, thus feces is too dry, hard or the enterokinesia that has a delicate constitution weak due to.There are " constipation caused by accumulation of heat ", " constipation of YIN type " to reach titles such as " spleen-constipation " in the treatise on Febrile Diseases.The present invention is meant heat intestine and stomach type constipation: constitution with overabundance of YANG, or insobriety usually, have a liking for the pungent savoury of food, so that gastrointestinal is red-hot, or after the calentura, waste heat is reluctant to leave, and consumption impairment of body fluid liquid causes intestinal scorching, and body fluid can not descend profit, so constipation with dry stool is difficult to discharge.Clinical manifestation: constipation with dry stool, oliguria with reddish urine, proctalgia in the time of just, or the abdominal part distension is arranged, xerostomia halitosis, vexed flushed complexion, dry and yellowish fur, arteries and veins bone number.

Its technical scheme is: get Radix Et Rhizoma Rhei 12 weight portions, Folium Sennae 9 weight portions, Fructus Gardeniae 9 weight portions, the Fructus Sophorae 12 weight portions, Radix Sanguisorbae 12 weight portions, Cacumen Platycladi 12 weight portions, Radix Rumicis Crispi 6 weight portions, Fructus Aurantii Immaturus 9 weight portions, Cortex Magnoliae Officinalis 9 weight portions, Bulbus Allii Macrostemonis 9 weight portions, Pericarpium Arecae 6 weight portions, Semen Persicae 12 weight portions, Radix Angelicae Sinensis 15 weight portions, Radix Scrophulariae 12 weight portions, Semen Sesami Nigrum 18 weight portions, Fructus Cannabis 6 weight portions, Semen Pruni 9 weight portions, Mel 9 weight portions, Semen Armeniacae Amarum 9 weight portions, Fructrs Trichosanthis 12 weight portions, the Radix Aucklandiae 9 weight portions, Semen Raphani 15 weight portions and Radix Glycyrrhizae 9 weight portions, above-mentioned medicine is put into 1350 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid removes slag with filtered through gauze, fried medicinal liquid is 500 milliliters altogether, is the Chinese medicine of treatment heat intestine and stomach type constipation.

The advantage of this invention is: make simply, this herb liquid side effect is little, toxicity is little.Oral back good absorbing in digestive tract, and stable curative effect are difficult for bounce-back.Avoided simultaneously that using sulfated magnesium, phenolphthalein, Oleum Ricini cause feel sick, untoward reaction and side effect such as vomiting, dehydration, erythra.Oral this Chinese medicine can make heat intestine and stomach type constipation obtain curing.Radix Et Rhizoma Rhei, Folium Sennae, the equal bitter in the mouth of this three flavor medicine of Fructus Gardeniae, cold in nature.Hardship can be rushed down down, the heat clearing away of cold energy.Effect with purging heat to relax the bowels.Wherein: Radix Et Rhizoma Rhei bowel relieving relieving constipation, eliminating fire and detoxication, eliminating blood stasis and inducing menstruation.The sedimentation of Radix Et Rhizoma Rhei bitter cold, abnormal smells from the patient is all thick.Power is apt to away suddenly, and the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels that can go directly is cleansed gastrointestinal retention, rushes down the blood system excess-heat clearly.Be used for the dry excrement of gastrointestinal dyspepsia, abdominal part distending pain, constipation.Or cause high fever with the high Sheng of excess-heat and do not move back unconsciousness and delirium.And can with the same usefulness of the medicine of a warm nature, following cold-excess syndrome is stagnant.Modern pharmacology confirms: the main component of Radix Et Rhizoma Rhei contains rheum-emodin and two kinds of materials of rheotannic acid.Its emodin can stimulate intestinal wall, improves intestinal and shrinks, secretes increase, makes intestinal contents be easy to discharge.Radix Et Rhizoma Rhei all has stronger vitro antibacterial activity to multiple gram negative bacterias such as multiple gram positive bacteria such as staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae and dysentery bacterium, Bacillus typhi, bacillus pyocyaneus, and the various skin fungus is also had in various degree bacteriostasis.Folium Sennae: sweet, bitter, cold.Go into large intestine channel.Purging heat to relax the bowels, the relieving distension of row water.The Folium Sennae bitter in the mouth is cold in nature, and matter is sticking and lubricate, rushes down and amasss heat and intestine moistening is dry so can go into large intestine, and the facilitating digestion effect is arranged, and is applicable to the disease of accumulation of heat food stagnation constipation, can manage it the water relieving distension again.Modern pharmacology confirms: the effective ingredient of Folium Sennae is that the cathartic acid class is about 15%, based on plain A of Senna fruit and B.At this moment, contain free anthraquinone derivative and mucus, calcium oxalate, phytosterol and fatty acid etc.Be the purgatives medicine that is good for the stomach.Fructus Gardeniae; Bitter, cold.Go into the heart, liver, lung, stomach, tri-jiao channel.The pathogenic fire purging relieving restlessness.The dampness removing that expels the heat-evil, cooling blood for hemostasis.The Fructus Gardeniae bitter cold is fallen clearly, and the property laxation is capable, the fire of the lung three warmers that can clear away heart-fire and diuresis.Modern pharmacology confirms: Fructus Gardeniae contains crocin, crocetin, Gardenia Yellow; And contain D-mannitol, B paddy propanol etc.That Fructus Gardeniae has is analgesic, calm, function of gallbladder promoting, antibacterial action.Can suppress the heating maincenter.Radix Et Rhizoma Rhei, Folium Sennae, the equal bitter in the mouth of Fructus Gardeniae are cold in nature, and the purging heat to relax the bowels effect is stronger, in the process of treatment heat intestine and stomach type constipation, play main therapeutical effect, so be monarch drug.The Fructus Sophorae, Radix Sanguisorbae, Cacumen Platycladi, Radix Rumicis Crispi, the equal bitter in the mouth of this 4 flavor medicine, cold in nature.All go into large intestine channel, cooling blood for hemostasis, the wherein double energy of Fructus Sophorae liver heat removing and eyesight improving; The double energy of Radix Sanguisorbae reducing swelling and alleviating pain; The double energy of Cacumen Platycladi growing and blacking hair; The double energy of Radix Rumicis Crispi parasite killing poison is treated the skin ulcer tinea, and clearing away damp-heat removes swollen itching.Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Bulbus Allii Macrostemonis, Pericarpium Arecae can be gone into stomach, large intestine channel, have the gas of capable gastrointestinal, the merit that stagnates of gastrointestinal.Fructus Aurantii Immaturus wherein: the dispelling the stagnated QI removing food stagnancy, circulation of qi promoting removes painful abdominal mass; Cortex Magnoliae Officinalis circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, lowering the adverse QI to relieve asthma; The Bulbus Allii Macrostemonis activating YANG and eliminating stagnation, making the adverse QI downward and promoting urination and defecation; Pericarpium Arecae therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, inducing diuresis to remove edema.Semen Persicae, Radix Angelicae Sinensis, Radix Scrophulariae, Semen Sesami Nigrum, Fructus Cannabis, Semen Pruni, Mel, Semen Armeniacae Amarum, Chinese juniper beach wormwood, this 9 flavor medical instrument has the merit of the laxation of moisturizing, loosening bowel to relieve constipation.Wherein Semen Persicae again can the removing blood stasis with potent drugs promoting the circulation of blood; The double energy of Radix Angelicae Sinensis tonifying blood and regulating menstruation, promoting blood circulation and stopping pain; Radix Scrophulariae is held concurrently and can be detoxified by pathogenic fire reducing; The double energy of Semen Sesami Nigrum nourishing the liver and kidney; Fructus Cannabis is held concurrently can nourish tonify deficiency; Semen Pruni is held concurrently and can be manageed it the water relieving distension; The double energy of Mel nourishing the lung to arrest cough, relieving spasm to stop pain; The double energy of Semen Armeniacae Amarum relieving cough and asthma; The double energy of Chinese juniper beach wormwood removing heat-phlegm, relieving epigastric distention and reducing the stagnation, carbuncle, loosening bowel to relieve constipation are treated in detumescence.The Fructus Sophorae, Radix Sanguisorbae, Cacumen Platycladi, Radix Rumicis Crispi, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Bulbus Allii Macrostemonis, Pericarpium Arecae, Semen Persicae, Radix Angelicae Sinensis, Radix Scrophulariae, Semen Sesami Nigrum, Fructus Cannabis, Semen Pruni, Mel, Semen Armeniacae Amarum, Chinese juniper beach wormwood, this 17 flavor medical instrument has the effect of the laxation of moisturizing, loosening bowel to relieve constipation, circulation of qi promoting, dispelling the stagnated QI, making the adverse QI downward and promoting urination and defecation, cooling blood for hemostasis.In the process of treatment heat intestine and stomach type constipation, can assist principal agent performance therapeutical effect, so be ministerial drug.The Radix Aucklandiae, Semen Raphani acrid in the mouth can loose, wherein Radix Aucklandiae suffering, hardship, temperature.Go into spleen, stomach, large intestine, tri-jiao channel.Promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion.Hot loose that hardship is fallen and temperature is logical, armaticity is dry, can rise to fall, current gastrointestinal, the three warmers stagnation of QI, all medicines of the rate focus of going directly.Semen Raphani; Hot, sweet, flat.Go into lung, spleen channel.Intestinal stasis relieving helps digestion, and lowering the adverse-rising QI to resolve phlegm is used for cards such as stagnation of QI due to dyspepsia, wrist abdominal distention is vexed, the belch food is smelly.The Radix Aucklandiae, Semen Raphani two medicines and the same usefulness of all medicines, its merit benefit is clear, so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.Can entangle the bias of all medicines, can separate the toxicity of all medicines again, so be messenger drug.Radix Et Rhizoma Rhei, Folium Sennae, Fructus Gardeniae, the Fructus Sophorae, Radix Sanguisorbae, Cacumen Platycladi, Radix Rumicis Crispi, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Bulbus Allii Macrostemonis, Pericarpium Arecae, Semen Persicae, Radix Angelicae Sinensis, Radix Scrophulariae, Semen Sesami Nigrum, Fructus Cannabis, Semen Pruni, Mel, Semen Armeniacae Amarum, Chinese juniper beach wormwood, the Radix Aucklandiae, Semen Raphani, Radix Glycyrrhizae.This 23 flavor medicine compatibility application has bowel relieving relieving constipation, purging heat to relax the bowels, pathogenic fire purging relieving restlessness, cooling blood for hemostasis, the circulation of qi promoting therapeutic method to keep the adverse QI flowing downwards, the merit that stagnates, moisturizes laxation, loosening bowel to relieve constipation of going.It is the ideal formulations of treatment heat intestine and stomach type constipation.Radix Et Rhizoma Rhei: bitter, cold.Go into stomach, large intestine, spleen, liver, pericardium channel.Bowel relieving relieving constipation, eliminating fire and detoxication, eliminating blood stasis and inducing menstruation.Folium Sennae: sweet, bitter, cold.Go into large intestine channel.Purging heat to relax the bowels, the relieving distension of row water.Fructus Gardeniae: bitter, cold.Go into the heart, liver, lung, stomach, tri-jiao channel.Pathogenic fire purging relieving restlessness, the dampness removing that expels the heat-evil, cooling blood for hemostasis.The Fructus Sophorae: hardship, cold.Go into liver, large intestine channel.Cooling blood for hemostasis, liver heat removing and eyesight improving.Radix Sanguisorbae: hardship, acid is slightly cold.Go into liver, stomach, large intestine channel.Cooling blood for hemostasis, reducing swelling and alleviating pain.Cacumen Platycladi: bitter, puckery, be slightly cold.Go into lung, liver, large intestine channel.Cooling blood for hemostasis, growing and blacking hair.Radix Rumicis Crispi: bitter, puckery, cold.Go into the heart, liver, large intestine channel.Cooling blood for hemostasis; The parasite killing poison is treated the skin ulcer tinea; Clearing away damp-heat removes swollen itching.Fructus Aurantii Immaturus: hardship is slightly cold.Go into spleen, stomach, large intestine channel.The dispelling the stagnated QI removing food stagnancy, circulation of qi promoting removes painful abdominal mass.Cortex Magnoliae Officinalis: bitter, hot, temperature.Go into spleen, stomach, large intestine channel.The circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, lowering the adverse QI to relieve asthma.Bulbus Allii Macrostemonis: hot, bitter, temperature.Go into lung, stomach, large intestine channel.Activating YANG and eliminating stagnation, making the adverse QI downward and promoting urination and defecation.Pericarpium Arecae: suffering, tepor.Go into spleen, stomach, large intestine channel, small intestine meridian.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, inducing diuresis to remove edema.Semen Persicae: bitter, sweet, flat.Go into the heart, liver, large intestine channel.Laxation is moisturized in the removing blood stasis with potent drugs promoting the circulation of blood.Radix Angelicae Sinensis: sweet, hot, sweet, temperature.Go into liver, the heart, spleen channel.Tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.Radix Scrophulariae: bitter, salty, be slightly cold.Go into kidney, lung meridian.Nourshing Yin and drynsessmoistening prescription, the pathogenic fire reducing detoxifcation.Semen Sesami Nigrum: sweet, flat.Go into spleen, lung, liver, kidney channel.Nourishing the liver and kidney is moisturized laxation.Fructus Cannabis: sweet, flat.Go into spleen, stomach, large intestine channel.Loosening bowel to relieve constipation nourishes tonify deficiency.Semen Pruni: hot, bitter, flat.Go into large intestine, small intestinal, spleen channel.Loosening bowel to relieve constipation, the relieving distension of row water.Mel: sweet, flat.Go into lung, spleen, large intestine channel.Loosening bowel to relieve constipation, nourishing the lung to arrest cough, emergency is ended carbuncle.Semen Armeniacae Amarum: bitter, hot, warm, slightly poisonous.Go into lung, large intestine channel.Relieving cough and asthma, loosening bowel to relieve constipation.Chinese juniper beach wormwood: sweet, cold.Go into lung, stomach, large intestine channel.Removing heat-phlegm, relieving epigastric distention and reducing the stagnation, carbuncle, loosening bowel to relieve constipation are treated in detumescence.The Radix Aucklandiae: hot, bitter, temperature.Go into spleen, stomach, large intestine, tri-jiao channel.Promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion.Semen Raphani: hot, sweet, flat.Go into lung, spleen channel.Intestinal stasis relieving helps digestion, lowering the adverse-rising QI to resolve phlegm.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, emergency is ended carbuncle, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.

The specific embodiment

Get Radix Et Rhizoma Rhei 12g, Folium Sennae 9g, Fructus Gardeniae 9g, Fructus Sophorae 12g, Radix Sanguisorbae 12g, Cacumen Platycladi 12g, Radix Rumicis Crispi 6g, Fructus Aurantii Immaturus 9g, Cortex Magnoliae Officinalis 9g, Bulbus Allii Macrostemonis 9g, Pericarpium Arecae 6g, Semen Persicae 12g, Radix Angelicae Sinensis 15g, Radix Scrophulariae 12g, Semen Sesami Nigrum 18g, Fructus Cannabis 6g, Semen Pruni 9g, Mel 9g, Semen Armeniacae Amarum 9g, Chinese juniper beach wormwood 12g, Radix Aucklandiae 9g, Semen Raphani 15g and Radix Glycyrrhizae 9g, above-mentioned medicine is put into 1350 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid removes slag with filtered through gauze, fried medicinal liquid is 500 milliliters altogether, is the Chinese medicine of treatment heat intestine and stomach type constipation.When the constipation patient need treat, each oral 250 milliliters, a twice-daily, fluid temperature is 36 ℃, three is a course of treatment, if still have symptoms such as constipation with dry stool, oliguria with reddish urine, obeys for second course of treatment again, so that recovery from illness.

Among the 338 routine heat intestine and stomach type constipation patients, male's 85 examples account for 25.15%; Women's 253 examples account for 74.85%, and the women is more than the male.

Among the patient of 338 routine heat intestine and stomach type constipations: 1～15 years old person, 12 examples account for 3.55%; 16～20 years old person's 13 examples account for 3.85%; 21～40,51 examples account for 15.09%; 41～60 years old person's 197 examples account for 58.28%; 61～85 years old person's 65 examples account for 19.23%.

The treatment natural law of 338 routine heat intestine and stomach type constipations is had nothing in common with each other.Wherein treat 1～3 day cured person, 171 examples account for 50.59%; 4～6 days persons, 129 examples account for 38.17%; 7～9 days persons, 30 examples account for 8.87%; 10～12 days persons, 3 examples account for 0.89%; 13～15 days persons, 3 examples account for 0.89%; 16～20 days persons, 2 examples account for 0.59%.

Information slip before and after the patient of 338 routine heat intestine and stomach type constipations

Claims

1. Chinese medicinal preparation method for the treatment of heat intestine and stomach type constipation, it is characterized in that: get Radix Et Rhizoma Rhei 12 weight portions, Folium Sennae 9 weight portions, Fructus Gardeniae 9 weight portions, the Fructus Sophorae 12 weight portions, Radix Sanguisorbae 12 weight portions, Cacumen Platycladi 12 weight portions, Radix Rumicis Crispi 6 weight portions, Fructus Aurantii Immaturus 9 weight portions, Cortex Magnoliae Officinalis 9 weight portions, Bulbus Allii Macrostemonis 9 weight portions, Pericarpium Arecae 6 weight portions, Semen Persicae 12 weight portions, Radix Angelicae Sinensis 15 weight portions, Radix Scrophulariae 12 weight portions, Semen Sesami Nigrum 18 weight portions, Fructus Cannabis 6 weight portions, Semen Pruni 9 weight portions, Mel 9 weight portions, Semen Armeniacae Amarum 9 weight portions, Chinese juniper beach wormwood 12 weight portions, the Radix Aucklandiae 9 weight portions, Semen Raphani 15 weight portions and Radix Glycyrrhizae 9 weight portions, above-mentioned medicine is put into 1350 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid removes slag with filtered through gauze, fried medicinal liquid is 500 milliliters altogether, is the Chinese medicine of treatment heat intestine and stomach type constipation.