CN101384900B - 流体输送机构 - Google Patents

流体输送机构 Download PDF

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Publication number
CN101384900B
CN101384900B CN2007800059677A CN200780005967A CN101384900B CN 101384900 B CN101384900 B CN 101384900B CN 2007800059677 A CN2007800059677 A CN 2007800059677A CN 200780005967 A CN200780005967 A CN 200780005967A CN 101384900 B CN101384900 B CN 101384900B
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CN
China
Prior art keywords
room
fluid
chamber
opening
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007800059677A
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English (en)
Chinese (zh)
Other versions
CN101384900A (zh
Inventor
亚拉戴尔·M·哈吉斯
罗奈德·C·查堤莱尔
盖瑞·钱柏斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universal Biosensors Pty Ltd
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Universal Biosensors Pty Ltd
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Publication date
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Publication of CN101384900A publication Critical patent/CN101384900A/zh
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0025Valves using microporous membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0688Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0073Fabrication methods specifically adapted for microvalves
    • F16K2099/008Multi-layer fabrications
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0082Microvalves adapted for a particular use
    • F16K2099/0086Medical applications
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Reciprocating Pumps (AREA)
CN2007800059677A 2006-02-21 2007-02-15 流体输送机构 Expired - Fee Related CN101384900B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77467806P 2006-02-21 2006-02-21
US60/774,678 2006-02-21
PCT/IB2007/000370 WO2007096730A1 (en) 2006-02-21 2007-02-15 Fluid transfer mechanism

Publications (2)

Publication Number Publication Date
CN101384900A CN101384900A (zh) 2009-03-11
CN101384900B true CN101384900B (zh) 2013-06-05

Family

ID=38436990

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800059677A Expired - Fee Related CN101384900B (zh) 2006-02-21 2007-02-15 流体输送机构

Country Status (18)

Country Link
US (1) US8182765B2 (enExample)
EP (1) EP1987353B1 (enExample)
JP (1) JP5154452B2 (enExample)
KR (1) KR101345428B1 (enExample)
CN (1) CN101384900B (enExample)
AU (1) AU2007219203B2 (enExample)
BR (1) BRPI0708131A2 (enExample)
CA (1) CA2643370C (enExample)
DK (1) DK1987353T3 (enExample)
ES (1) ES2389382T3 (enExample)
IL (1) IL193352A (enExample)
MX (1) MX2008010719A (enExample)
NZ (1) NZ571322A (enExample)
PL (1) PL1987353T3 (enExample)
PT (1) PT1987353E (enExample)
TW (1) TWI402341B (enExample)
WO (1) WO2007096730A1 (enExample)
ZA (1) ZA200807527B (enExample)

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US8187541B2 (en) * 2006-09-18 2012-05-29 California Institute Of Technology Apparatus for detecting target molecules and related methods
EP2072133A1 (en) 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Multi-compartment device with magnetic particles
WO2010016916A2 (en) * 2008-08-07 2010-02-11 The University Of North Carolina At Chapel Hill Method of creating removable barriers in microfabricated fluidic devices
JP5847074B2 (ja) 2009-04-17 2016-01-20 ユニバーサル バイオセンサーズ ピーティーワイ リミテッドUniversal Biosensors Pty Limited 基板上対照検出
EP2451576B1 (en) * 2009-07-09 2019-06-12 Alere Switzerland GmbH Device and method for analyzing analyte in liquid sample
WO2012092394A1 (en) 2010-12-29 2012-07-05 Cardinal Health 414, Llc Closed vial fill system for aseptic dispensing
US8956518B2 (en) 2011-04-20 2015-02-17 Lifescan, Inc. Electrochemical sensors with carrier field
US20130020727A1 (en) 2011-07-15 2013-01-24 Cardinal Health 414, Llc. Modular cassette synthesis unit
US20130102772A1 (en) 2011-07-15 2013-04-25 Cardinal Health 414, Llc Systems, methods and devices for producing, manufacturing and control of radiopharmaceuticals-full
US9417332B2 (en) 2011-07-15 2016-08-16 Cardinal Health 414, Llc Radiopharmaceutical CZT sensor and apparatus
WO2013036617A1 (en) 2011-09-06 2013-03-14 President And Fellows Of Harvard College Microfluidic devices for multiplexed electrochemical detection
US9623407B2 (en) * 2015-03-27 2017-04-18 International Business Machines Corporation Microfluidic device with longitudinal and transverse liquid barriers for transverse flow mixing
WO2017040946A1 (en) * 2015-09-03 2017-03-09 The Charles Stark Draper Laboratory, Inc. Modular chemical sensor platform
US11499962B2 (en) 2017-11-17 2022-11-15 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10273528B1 (en) 2017-11-17 2019-04-30 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10512911B1 (en) 2018-12-07 2019-12-24 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US12239980B2 (en) 2018-12-07 2025-03-04 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
CN209829010U (zh) * 2019-03-01 2019-12-24 南京岚煜生物科技有限公司 一种多通道微流体凝血检测芯片
US11118223B2 (en) 2019-03-14 2021-09-14 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
WO2020194179A1 (en) * 2019-03-24 2020-10-01 Baldwa Mehul Biosensor for detection of analytes in a fluid

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US20040121450A1 (en) * 2002-12-19 2004-06-24 Pugia Michael J. Method and apparatus for splitting of specimens into multiple channels of a microfluidic device

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EP0057110A2 (en) * 1981-01-28 1982-08-04 EASTMAN KODAK COMPANY (a New Jersey corporation) Reaction vessel and method for combining liquids and reagents
US20040121450A1 (en) * 2002-12-19 2004-06-24 Pugia Michael J. Method and apparatus for splitting of specimens into multiple channels of a microfluidic device

Also Published As

Publication number Publication date
PT1987353E (pt) 2012-09-06
JP2009527676A (ja) 2009-07-30
IL193352A0 (en) 2009-05-04
NZ571322A (en) 2011-08-26
EP1987353B1 (en) 2012-06-13
CA2643370A1 (en) 2007-08-30
BRPI0708131A2 (pt) 2011-05-17
HK1124665A1 (en) 2009-07-17
ES2389382T3 (es) 2012-10-25
TW200813215A (en) 2008-03-16
EP1987353A1 (en) 2008-11-05
US8182765B2 (en) 2012-05-22
AU2007219203B2 (en) 2012-12-20
JP5154452B2 (ja) 2013-02-27
ZA200807527B (en) 2009-07-29
KR20090034298A (ko) 2009-04-07
US20090305431A1 (en) 2009-12-10
DK1987353T3 (da) 2012-09-10
CA2643370C (en) 2014-06-03
CN101384900A (zh) 2009-03-11
EP1987353A4 (en) 2010-11-17
WO2007096730A1 (en) 2007-08-30
KR101345428B1 (ko) 2013-12-27
PL1987353T3 (pl) 2012-11-30
AU2007219203A1 (en) 2007-08-30
TWI402341B (zh) 2013-07-21
MX2008010719A (es) 2008-09-01
IL193352A (en) 2014-01-30

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